DOI: 10.1038/257185a0. Opiate receptor in normal and drug altered brain function*

Opiate receptor in normal and drug altered brain function*

10.1038/257185a0

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Authors 1

Solomon H. Snyder (first)

References 57 Referenced 159

Goldstein, A., Lowney, L. L., and Pal, B. K., Proc. natn. Acad. Sci. U.S.A., 68, 1742–1747 (1971). (10.1073/pnas.68.8.1742) / Proc. natn. Acad. Sci. U.S.A. by A Goldstein (1971)
Pert, C. B., and Snyder, S. H., Science, 179, 1011–1014 (1973). (10.1126/science.179.4077.1011) / Science by CB Pert (1973)
Pert, C. B., and Snyder, S. H., Proc. natn. Acad. Sci. U.S.A., 70, 2243–2247 (1973). (10.1073/pnas.70.8.2243) / Proc. natn. Acad. Sci. U.S.A. by CB Pert (1973)
Terenius, L., Acta Pharmacol. Toxicol., 32, 317–320 (1973). (10.1111/j.1600-0773.1973.tb01477.x) / Acta Pharmacol. Toxicol. by L Terenius (1973)
Simon, E. J., Hiller, J. M., and Edelman, I., Proc. natn. Acad. Sci. U.S.A., 70, 1947–1949 (1973). (10.1073/pnas.70.7.1947) / Proc. natn. Acad. Sci. U.S.A. by EJ Simon (1973)
Snyder, S. H., Pasternak, G. W., and Pert, C. B., in Handbook of Psychopharmacology (edit. by Iversen, L. L., Iversen, S. D., and Snyder, S. H.), 329–360. (Plenum, New York, 1975). / Handbook of Psychopharmacology by SH Snyder (1975)
Loh, H. H., Cho, T. M., Wu, Y.-C., and Way, E. L., Life Sci., 14, 2231–2245 (1974). (10.1016/0024-3205(74)90105-2) / Life Sci. by HH Loh (1974)
Abood, L. G.,, Hoss, W. P., Psychopharmacol. Commun., 1, 29–36 (1975). / Psychopharmacol. Commun. by LG Abood (1975)
Paton, W. D. M., Br. J. Pharmac. Chemother., 12, 119–127 (1957). (10.1111/j.1476-5381.1957.tb01373.x) / Br. J. Pharmac. Chemother. by WDM Paton (1957)
Kosterlitz, H. W., and Waterfield, A. A., A. Rev. Pharmac., 15, 29–47 (1975). (10.1146/annurev.pa.15.040175.000333) / A. Rev. Pharmac. by HW Kosterlitz (1975)
Creese, I., and Snyder, S. H., J. Pharmac. exp. Ther., 194, 205–219 (1975). / J. Pharmac. exp. Ther. by I Creese (1975)
Lasagna, L., Pharmac. Rev., 16, 47–83 (1964). / Pharmac. Rev. by L Lasagna (1964)
Pert, C. B., Pasternak, G. W., and Snyder, S. H., Science, 182, 1359–1361 (1973). (10.1126/science.182.4119.1359) / Science by CB Pert (1973)
Pert, C. B., and Snyder, S. H., Molec. Pharmac., 10, 868–879 (1974). / Molec. Pharmac. by CB Pert (1974)
Simon, E. J., Hiller, J. M., Groth, J., and Edelman, I., J. Pharmac. exp. Ther., 192, 531–537 (1975). / J. Pharmac. exp. Ther. by EJ Simon (1975)
Pasternak, G. W., and Snyder, S. H., Nature, 253, 563–565 (1975). (10.1038/253563a0) / Nature by GW Pasternak (1975)
Snyder, S. H., Neurosci. Res. Prog. Bull., 13, 137–141 (1975). / Neurosci. Res. Prog. Bull. by SH Snyder (1975)
Pasternak, G. W., and Snyder, S. H., Molec. Pharmac., 10, 183–193 (1974). / Molec. Pharmac. by GW Pasternak (1974)
Pasternak, G. W., and Snyder, S. H., Molec. Pharmac., 11, 478–484 (1975). / Molec. Pharmac. by GW Pasternak (1975)
Pasternak, G. W., Wilson, H. A., and Snyder, S. H., Molec. Pharmac., 11, 340–351 (1975). / Molec. Pharmac. by GW Pasternak (1975)
Wilson, H. A., Pasternak, G. W., and Snyder, S. H., Nature, 253, 448–450 (1975). (10.1038/253448a0) / Nature by HA Wilson (1975)
Pasternak, G. W., Snowman, A., and Snyder, S. H., Molec. Pharmac. (in the press).
Karlin, A., J. theor. Biol., 16, 306–320 (1967). (10.1016/0022-5193(67)90011-2) / J. theor. Biol. by A Karlin (1967)
Changeux, J. -P., and Podleski, T. R., Proc. natn. Acad. Sci. U.S.A., 59, 944–950 (1968). (10.1073/pnas.59.3.944) / Proc. natn. Acad. Sci. U.S.A. by J-P Changeux (1968)
Snyder, S. H., Biochem. Pharmac., 24, 1371–1374 (1975). (10.1016/0006-2952(75)90358-5) / Biochem. Pharmac. by SH Snyder (1975)
Young, A. B., and Snyder, S. H., Proc. natn. Acad. Sci. U.S.A., 70, 2832–2836 (1973). (10.1073/pnas.70.10.2832) / Proc. natn. Acad. Sci. U.S.A. by AB Young (1973)
Young, A. B., and Snyder, S. H., Proc. natn. Acad. Sci. U.S.A., 71, 4002–4005 (1974). (10.1073/pnas.71.10.4002) / Proc. natn. Acad. Sci. U.S.A. by AB Young (1974)
Nauta, W. J. H., Neurosci. Res. Prog. Bull., 13, 84–87 (1975). / Neurosci. Res. Prog. Bull. by WJH Nauta (1975)
Kuhar, M. J., Pert, C. B., and Snyder, S. H., Nature, 245, 447–450 (1973). (10.1038/245447a0) / Nature by MJ Kuhar (1973)
Hiller, J. M., Pearson, J., and Simon, E. J., Res. Commun. chem. pathol. Pharmac., 6, 1052–1062 (1973). / Res. Commun. chem. pathol. Pharmac. by JM Hiller (1973)
Pert, A., and Yaksh, T., Brain Res., 80, 135–140 (1974). (10.1016/0006-8993(74)90731-8) / Brain Res. by A Pert (1974)
Wei, E. L., Loh, H. H., and Way, E. L., J. pharmac. exp. Ther., 185, 108–115 (1973). / J. pharmac. exp. Ther. by EL Wei (1973)
Pert, C. B., Kuhar, M. J., and Snyder, S. H., Life Sci., 16, 1849–1854 (1975). (10.1016/0024-3205(75)90289-1) / Life Sci. by CB Pert (1975)
Pert, C. B., and Snyder, S. H., Life Sci., 16, 1623–1634 (1975). (10.1016/0024-3205(75)90080-6) / Life Sci. by CB Pert (1975)
Korf, J., Bunney, B. S., and Aghajanian, G. K., Eur. J. Pharmac., 25, 165–169 (1974). (10.1016/0014-2999(74)90045-4) / Eur. J. Pharmac. by J Korf (1974)
way, E. L., Neurosci. Res. Prog. Bull., 13, 112–118 (1975). / Neurosci. Res. Prog. Bull. by EL way (1975)
Pert, C. B., Aposhian, D., and Snyder, S. H., Brain Res., 75, 356–361 (1974). (10.1016/0006-8993(74)90761-6) / Brain Res. by CB Pert (1974)
Pert, C. B., Snowman, A. M., and Snyder, S. H., Brain Res., 70, 184–188 (1974). (10.1016/0006-8993(74)90228-5) / Brain Res. by CB Pert (1974)
Hughes, J., Brain Res., 88, 1–14 (1975). (10.1016/0006-8993(75)90391-1) / Brain Res. by J Hughes (1975)
Terenius, L., and Wahlström, A., Life Sci., 16, 1759–1764 (1975). (10.1016/0024-3205(75)90269-6) / Life Sci. by L Terenius (1975)
Pasternak, G. W., Goodman, R., and Snyder, S. H., Life Sci., 16, 1765–1769 (1975). (10.1016/0024-3205(75)90270-2) / Life Sci. by GW Pasternak (1975)
Hughes, J., Life Sci. (in the press).
Teschmacher, H., Opheim, K., Cox, B. M., and Goldstein, A., Life Sci., 16, 1771–1776 (1975). (10.1016/0024-3205(75)90271-4) / Life Sci. by H Teschmacher (1975)
Satoh, M., Zieglgansberger, F. W., and Herz, A., Brain Res., 82, 378–382 (1974). (10.1016/0006-8993(74)90624-6) / Brain Res. by M Satoh (1974)
Cochin, J., Fedn Proc., 29, 19–27 (1974). / Fedn Proc. by J Cochin (1974)
Collier, H. O. J., Adv. Drug Res., 3, 171–188 (1966). / Adv. Drug Res. by HOJ Collier (1966)
Goldstein, D. B., and Goldstein, A., Biochem. Pharmac., 8, 48 (Abstr. No. 152) (1961). (10.1016/0006-2952(61)90329-X) / Biochem. Pharmac. by DB Goldstein (1961)
Shuster, L., Nature, 189, 314–315 (1961). (10.1038/189314a0) / Nature by L Shuster (1961)
Martin, W. R., Fedn Proc., 29, 13–18 (1970). / Fedn Proc. by WR Martin (1970)
Klee, W. A., and Streaty, R. A., Nature, 248, 61–63 (1974). (10.1038/248061a0) / Nature by WA Klee (1974)
Klee, W. A., and Nirenberg, M., Proc. natn. Acad. Sci. U.S.A., 71, 3474–3477 (1974). (10.1073/pnas.71.9.3474) / Proc. natn. Acad. Sci. U.S.A. by WA Klee (1974)
Sharma, S. K., Nirenberg, M., and Klee, W. A., Proc. natn. Acad. Sci. U.S.A., 72, 590–594 (1974). (10.1073/pnas.72.2.590) / Proc. natn. Acad. Sci. U.S.A. by SK Sharma (1974)
Traber, J., Gullis, R., and Hamprecht, B., Life Sci., 16, 1863–1868 (1975). (10.1016/0024-3205(75)90292-1) / Life Sci. by J Traber (1975)
Klee, W. A., Sharma, S. K., and Nirenberg, M., Life Sci. (in the press).
Collier, H. O. J., and Roy, A. C., Nature, 248, 24–27 (1974). (10.1038/248024a0) / Nature by HOJ Collier (1974)
Collier, H. O. J., Francis, D. L., Henderson, G., and Schneider, C., Nature, 249, 471–473 (1974). (10.1038/249471a0) / Nature by HOJ Collier (1974)
Francis, D. L., Roy, A. C., and Collier, H. O. J., Life Sci., 16, 1901–1906 (1975). (10.1016/0024-3205(75)90299-4) / Life Sci. by DL Francis (1975)

Dates

Type	When
Created	20 years ago (Aug. 3, 2005, 2:02 p.m.)
Deposited	2 years, 3 months ago (May 16, 2023, 8:15 p.m.)
Indexed	4 months, 3 weeks ago (April 8, 2025, 9:58 p.m.)
Issued	50 years ago (Sept. 1, 1975)
Published	50 years ago (Sept. 1, 1975)
Published Print	50 years ago (Sept. 1, 1975)

Funders 0

None

BibTeX

@article{Snyder_1975, title={Opiate receptor in normal and drug altered brain function*}, volume={257}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/257185a0}, DOI={10.1038/257185a0}, number={5523}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Snyder, Solomon H.}, year={1975}, month=sep, pages={185–189} }

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