DOI: 10.1038/21913. DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage

DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage

10.1038/21913

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Jimenez, G. S., Bryntesson, F., Torres-Arzayus, M. I., Priestley, A., Beeche, M., Saito, S., Sakaguchi, K., Appella, E., Jeggo, P. A., Taccioli, G. E., Wahl, G. M., & Hubank, M. (1999). DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage. Nature, 400(6739), 81â83.

Authors 12

Gretchen S. Jimenez (first)
Fredrik Bryntesson (additional)
Maria I. Torres-Arzayus (additional)
Anne Priestley (additional)
Michelle Beeche (additional)
Shin'ichi Saito (additional)
Kazuyasu Sakaguchi (additional)
Ettore Appella (additional)
Penny A. Jeggo (additional)
Guillermo E. Taccioli (additional)
Geoffrey M. Wahl (additional)
Michael Hubank (additional)

References 19 Referenced 107

Levine, A. J. p53, the cellular gatekeeper for growth and division. Cell 88, 323–331 (1997). (10.1016/S0092-8674(00)81871-1) / Cell by AJ Levine (1997)
Prives, C. Signaling to p53: breaking the MDM2–p53 circuit. Cell 95, 5–8 (1998). (10.1016/S0092-8674(00)81774-2) / Cell by C Prives (1998)
Woo, R. A., McLure, K. G., Lees-Miller, S. P., Rancourt, D. E. & Lee, P. W. DNA-dependent protein kinase acts upstream of p53 in response to DNA damage. Nature 394, 700–704 (1998). (10.1038/29343) / Nature by RA Woo (1998)
Smith, G. C. & Jackson, S. P. The DNA-dependent protein kinase. Genes Dev. 13, 916–934 (1999). (10.1101/gad.13.8.916) / Genes Dev. by GC Smith (1999)
Taccioli, G. E. et al . Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity. Immunity 9, 355–366 (1998). (10.1016/S1074-7613(00)80618-4) / Immunity by GE Taccioli (1998)
Giaccia, A. J. & Kastan, M. B. The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev 12, 2973–2983 (1998). (10.1101/gad.12.19.2973) / Genes Dev by AJ Giaccia (1998)
Lees-Miller, S. P., Sakaguchi, K., Ullrich, S. J., Appella, E. & Anderson, C. W. Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. Mol. Cell. Biol. 12, 5041–5049 (1992). (10.1128/MCB.12.11.5041) / Mol. Cell. Biol. by SP Lees-Miller (1992)
Tibbetts, R. S. et al . Arole for ATR in the DNA damage-induced phosphorylation of p53. Genes Dev. 13, 152–157 (1999). (10.1101/gad.13.2.152) / Genes Dev. by RS Tibbetts (1999)
Jeggo, P. A. DNA-PK: at the cross-roads of biochemistry and genetics. Mutat. Res. 384, 1–14 (1997). (10.1016/S0921-8777(97)00009-8) / Mutat. Res. by PA Jeggo (1997)
Hainaut, P. et al . Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects. Nucleic Acids Res. 25, 151–157 (1997). (10.1093/nar/25.1.151) / Nucleic Acids Res. by P Hainaut (1997)
Rathmell, W. K., Kaufmann, W. K., Hurt, J. C., Byrd, L. L. & Chu, G. DNA-dependent protein kinase isnot required for accumulation of p53 or cell cycle arrest after DNA damage. Cancer Res. 57, 68–74 (1997). / Cancer Res. by WK Rathmell (1997)
Nussenzweig, A. et al . Requirement for Ku80 in growth and immunoglobulin V(D)J recombination. Nature 382, 551–555 (1996). (10.1038/382551a0) / Nature by A Nussenzweig (1996)
Huang, L. C., Clarkin, K. C. & Wahl, G. M. p53-dependent cell cycle arrests are preserved in DNA-activated protein kinase-deficient mouse fibroblasts. Cancer Res. 56, 2940–2944 (1996). / Cancer Res. by LC Huang (1996)
Gu, Y. et al . Growth retardation and leaky SCID phenotype of Ku70-deficient mice. Immunity 7, 653–665 (1997). (10.1016/S1074-7613(00)80386-6) / Immunity by Y Gu (1997)
Zhu, C., Bogue, M. A., Lim, D. S., Hasty, P. & Roth, D. B. Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell 86, 379–389 (1996). (10.1016/S0092-8674(00)80111-7) / Cell by C Zhu (1996)
Jongmans, W. et al . The role of ataxia telangiectasia and the DNA-dependent protein kinase in the p53-mediated cellular response to ionising radiation. Oncogene 13, 1133–1138 (1996). / Oncogene by W Jongmans (1996)
Linke, S. P., Clarkin, K. C., Di Leonardo, A., Tsou, A. & Wahl, G. M. Areversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. Genes Dev. 10, 934–947 (1996). (10.1101/gad.10.8.934) / Genes Dev. by SP Linke (1996)
Sakaguchi, K. et al . DNA damage activated p53 through a phosphorylation–acetylation cascade. Genes Dev. 12, 2831–2841 (1998). (10.1101/gad.12.18.2831) / Genes Dev. by K Sakaguchi (1998)
McLure, K. G. & Lee, P. W. How p53 binds DNA as a tetramer. EMBO J. 17, 3342–3350 (1998). (10.1093/emboj/17.12.3342) / EMBO J. by KG McLure (1998)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 4:41 a.m.)
Deposited	3 years, 8 months ago (Dec. 1, 2021, 3:10 p.m.)
Indexed	11 months, 2 weeks ago (Sept. 16, 2024, 11:50 a.m.)
Issued	26 years, 1 month ago (July 1, 1999)
Published	26 years, 1 month ago (July 1, 1999)
Published Print	26 years, 1 month ago (July 1, 1999)

Funders 0

None

BibTeX

@article{Jimenez_1999, title={DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage}, volume={400}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/21913}, DOI={10.1038/21913}, number={6739}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Jimenez, Gretchen S. and Bryntesson, Fredrik and Torres-Arzayus, Maria I. and Priestley, Anne and Beeche, Michelle and Saito, Shin’ichi and Sakaguchi, Kazuyasu and Appella, Ettore and Jeggo, Penny A. and Taccioli, Guillermo E. and Wahl, Geoffrey M. and Hubank, Michael}, year={1999}, month=jul, pages={81–83} }

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