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Imai, Y., Kimura, T., Murakami, A., Yajima, N., Sakamaki, K., & Yonehara, S. (1999). The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis. Nature, 398(6730), 777–785.

Authors 6
  1. Yuzuru Imai (first)
  2. Takaharu Kimura (additional)
  3. Akira Murakami (additional)
  4. Nobuyuki Yajima (additional)
  5. Kazuhiro Sakamaki (additional)
  6. Shin Yonehara (additional)
References 48 Referenced 203
  1. Itoh, N.et al. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66, 233– 243 (1991). (10.1016/0092-8674(91)90614-5) / Cell by N Itoh (1991)
  2. Nagata, S. Apoptosis by death factor. Cell 88, 355– 365 (1997). (10.1016/S0092-8674(00)81874-7) / Cell by S Nagata (1997)
  3. Yonehara, S., Ishii, A. & Yonehara, M. Acell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J. Exp. Med. 169, 1747– 1756 (1989). (10.1084/jem.169.5.1747) / J. Exp. Med. by S Yonehara (1989)
  4. Trauth, B. C.et al. Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 245, 301– 305 (1989). (10.1126/science.2787530) / Science by BC Trauth (1989)
  5. Suda, T., Takahashi, T., Golstein, P. & Nagata, S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75, 1169 –1178 (1993). (10.1016/0092-8674(93)90326-L) / Cell by T Suda (1993)
  6. Chinnaiyan, A. M., O'Rourke, K., Tewari, M. & Dixit, V. M. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81, 505– 512 (1995). (10.1016/0092-8674(95)90071-3) / Cell by AM Chinnaiyan (1995)
  7. Boldin, M. P.et al. Anovel protein that interacts with the death domain of Fas/APO1 contain a sequence motif related to the death domain. J. Biol. Chem. 270, 7795–7798 ( 1995). (10.1074/jbc.270.14.7795) / J. Biol. Chem. by MP Boldin (1995)
  8. Yeh, W. C.et al. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 279, 1954–1958 (1998). (10.1126/science.279.5358.1954) / Science by WC Yeh (1998)
  9. Zhang, J.et al. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 392, 296–300 (1998). (10.1038/32681) / Nature by J Zhang (1998)
  10. Kischkel, F. C.et al . Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 14, 5579–5588 ( 1995). (10.1002/j.1460-2075.1995.tb00245.x) / EMBO J. by FC Kischkel (1995)
  11. Boldin, M. P., Goncharov, T. M., Goltsev, Y. V. & Wallach, D. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 85, 803–815 (1996). (10.1016/S0092-8674(00)81265-9) / Cell by MP Boldin (1996)
  12. Muzio, M.et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 85, 817–827 ( 1996). (10.1016/S0092-8674(00)81266-0) / Cell by M Muzio (1996)
  13. Muzio, M.et al. An induced proximity model for caspase-8 activation. J. Biol. Chem. 273, 2926–2930 (1998). (10.1074/jbc.273.5.2926) / J. Biol. Chem. by M Muzio (1998)
  14. Yang, X., Chang, H. Y. & Baltimore, D. Autoproteolytic activation of pro-caspases by oligomerization. Mol. Cell 1, 319–325 (1998). (10.1016/S1097-2765(00)80032-5) / Mol. Cell by X Yang (1998)
  15. Enari, M., Talanian, R. V., Wong, W. W. & Nagata, S. Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380, 723– 726 (1996). (10.1038/380723a0) / Nature by M Enari (1996)
  16. Takahashi, A.et al. Affinity labeling displays the stepwise activation of ICR-related proteases by Fas, staurosporine, and CrmA-sensitive caspase-8. Oncogene 14, 2741–2752 ( 1997). (10.1038/sj.onc.1201131) / Oncogene by A Takahashi (1997)
  17. Fernandes-Alnemri, T., Litwack, G. & Alnemri, E. S. Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family. Cancer Res. 55, 2737 –2742 (1995). / Cancer Res. by T Fernandes-Alnemri (1995)
  18. Villa, P., Kaufmann, S. H. & Earnshaw, W. C. Caspases and caspase inhibitors. Trends Biochem. Sci. 22, 388–393 (1997). (10.1016/S0968-0004(97)01107-9) / Trends Biochem. Sci. by P Villa (1997)
  19. Rudel, T. & Bokoch, G. M. Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science 276, 1571–1571 ( 1997). (10.1126/science.276.5318.1571) / Science by T Rudel (1997)
  20. Enari, M.et al. Acaspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391, 43– 50 (1998). (10.1038/34112) / Nature by M Enari (1998)
  21. Chinnaiyan, A. M.et al. Role of CED-4 in the activation of CED-3. Nature 388, 728–729 ( 1997). (10.1038/41913) / Nature by AM Chinnaiyan (1997)
  22. Li, P.et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479–489 (1997). (10.1016/S0092-8674(00)80434-1) / Cell by P Li (1997)
  23. Perez, D. & White, E. E1B 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE. J. Cell Biol. 141, 1255–1266 (1998). (10.1083/jcb.141.5.1255) / J. Cell Biol. by D Perez (1998)
  24. Scaffidi, C.et al. Two CD95 (APO-1/Fas) signaling pathways. EMBO J. 17, 1675–1687 ( 1998). (10.1093/emboj/17.6.1675) / EMBO J. by C Scaffidi (1998)
  25. Kozak, M. The scanning model for translation: an update. J. Cell Biol. 108, 229–241 (1989). (10.1083/jcb.108.2.229) / J. Cell Biol. by M Kozak (1989)
  26. Walker, J. E., Saraste, M., Runswick, M. J. & Gay, N. J. Distantly related sequences in the alpha- and beta-subunits of ATP synthetase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1, 945–951 (1982). (10.1002/j.1460-2075.1982.tb01276.x) / EMBO J. by JE Walker (1982)
  27. Nigg, E. A. Nucleocytoplasmic transport: signals, mechanisms and regulation. Nature 386, 779–787 ( 1997). (10.1038/386779a0) / Nature by EA Nigg (1997)
  28. Wada, A., Fukuda, M., Mishima, M. & Nishida, E. Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein. EMBO J. 17, 1635– 1741 (1998). (10.1093/emboj/17.6.1635) / EMBO J. by A Wada (1998)
  29. Medema, J. P.et al. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16, 2794 –2804 (1997). (10.1093/emboj/16.10.2794) / EMBO J. by JP Medema (1997)
  30. Yang, X., Chang, H. Y. & Baltimore, D. Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. Science 281, 1355– 1357 (1998). (10.1126/science.281.5381.1355) / Science by X Yang (1998)
  31. Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T. & Alnemri, E. S. Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. Mol. Cell 1, 949–957 ( 1998). (10.1016/S1097-2765(00)80095-7) / Mol. Cell by SM Srinivasula (1998)
  32. Liu, X., Zou, H., Slaughter, C. & Wang, X. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89, 175– 184 (1997). (10.1016/S0092-8674(00)80197-X) / Cell by X Liu (1997)
  33. Stegh, A. H.et al. DEDD, a novel death effector domain-containing protein, targeted to the nucleolus. EMBO J. 17, 5974– 5986 (1998). (10.1093/emboj/17.20.5974) / EMBO J. by AH Stegh (1998)
  34. Medema, J. P., Scaffidi, C., Krammer, P. H. & Peter, M. E. Bcl-xL acts downstream of caspase-8 activation by the CD95 death-inducing signaling complex. J. Biol. Chem. 273, 3388 –3393 (1998). (10.1074/jbc.273.6.3388) / J. Biol. Chem. by JP Medema (1998)
  35. Li, H., Zhu, H., Xu, C. J. & Yuan, J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94, 491–501 (1998). (10.1016/S0092-8674(00)81590-1) / Cell by H Li (1998)
  36. Luo, X.et al. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94, 481–490 ( 1998). (10.1016/S0092-8674(00)81589-5) / Cell by X Luo (1998)
  37. Chinnaiyan, A. M., O'Rourke, K., Lane, B. R. & Dixit, V. M. Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death. Science 275, 1122– 1126 (1997). (10.1126/science.275.5303.1122) / Science by AM Chinnaiyan (1997)
  38. Hengartner, M. O. Apoptosis. CED-4 is a stranger no more. Nature 388, 714–715 (1997). (10.1038/41873) / Nature by MO Hengartner (1997)
  39. Yang, J.et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275, 1129– 1132 (1997). (10.1126/science.275.5303.1129) / Science by J Yang (1997)
  40. Kluck, R. M., Bossy-Wetzel, E., Green, D. R. & Newmeyer, D. D. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275, 1132– 1136 (1997). (10.1126/science.275.5303.1132) / Science by RM Kluck (1997)
  41. Pan, G., O'Rourke, K. & Dixit, V. M. Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex. J. Biol. Chem. 273, 5841– 5845 (1998). (10.1074/jbc.273.10.5841) / J. Biol. Chem. by G Pan (1998)
  42. Hu, Y.et al. Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation. Proc. Natl Acad. Sci. USA 95, 4386– 4391 (1998). (10.1073/pnas.95.8.4386) / Proc. Natl Acad. Sci. USA by Y Hu (1998)
  43. Sakamaki, K., Tsukumo, S. & Yonehara, S. Molecular cloning and characterization of mouse caspase-8. Eur. J. Biochem. 253, 399– 405 (1998). (10.1046/j.1432-1327.1998.2530399.x) / Eur. J. Biochem. by K Sakamaki (1998)
  44. 4. Sakamaki, K., Miyajima, I., Kitamura, T. & Miyajima, A. Critical cytoplasmic domains of the common beta subunit of the human GM- CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation. EMBO J. 11, 3541–3549 (1992). (10.1002/j.1460-2075.1992.tb05437.x) / EMBO J. by K Sakamaki (1992)
  45. Nishimura, Y.et al. Expression and function of mouse Fas antigen on immature and mature T cells. J. Immunol. 154, 4395– 4403 (1995). (10.4049/jimmunol.154.9.4395) / J. Immunol. by Y Nishimura (1995)
  46. Eberstadt, M.et al. NMR structure and mutagenesis of the FADD (Mort1) death-effector domain. Nature 392, 941– 945 (1998). (10.1038/31972) / Nature by M Eberstadt (1998)
  47. van der Biezen, E. A. & Jones, J. D. The NB-ARC domain: a novel signaling motif shared by plant resistance gene products and regulators of cell death in animals. Curr. Biol. 8, R226–227 (1998). (10.1016/S0960-9822(98)70145-9) / Curr. Biol. by EA van der Biezen (1998)
  48. Yonehara, S.et al. Involvement of apoptosis antigen Fas in clonal deletion of human thymocytes. Int. Immunol. 6, 1849– 1856 (1994). (10.1093/intimm/6.12.1849) / Int. Immunol. by S Yonehara (1994)
Dates
Type When
Created 23 years, 1 month ago (July 26, 2002, 4:39 a.m.)
Deposited 2 years, 4 months ago (April 20, 2023, 7:16 p.m.)
Indexed 2 months ago (June 30, 2025, 7:26 a.m.)
Issued 26 years, 4 months ago (April 29, 1999)
Published 26 years, 4 months ago (April 29, 1999)
Published Print 26 years, 4 months ago (April 29, 1999)
Funders 0

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@article{Imai_1999, title={The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis}, volume={398}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/19709}, DOI={10.1038/19709}, number={6730}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Imai, Yuzuru and Kimura, Takaharu and Murakami, Akira and Yajima, Nobuyuki and Sakamaki, Kazuhiro and Yonehara, Shin}, year={1999}, month=apr, pages={777–785} }