DOI: 10.1038/18899. A new secreted protein that binds to Wnt proteins and inhibits their activites

A new secreted protein that binds to Wnt proteins and inhibits their activites

10.1038/18899

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Hsieh, J.-C., Kodjabachian, L., Rebbert, M. L., Rattner, A., Smallwood, P. M., Samos, C. H., Nusse, R., Dawid, I. B., & Nathans, J. (1999). A new secreted protein that binds to Wnt proteins and inhibits their activites. Nature, 398(6726), 431â436.

Authors 9

Jen-Chih Hsieh (first)
Laurent Kodjabachian (additional)
Martha L. Rebbert (additional)
Amir Rattner (additional)
Philip M. Smallwood (additional)
Cynthia Harryman Samos (additional)
Roel Nusse (additional)
Igor B. Dawid (additional)
Jeremy Nathans (additional)

References 17 Referenced 597

Wodarz, A. & Nusse, R. Mechanisms of Wnt signaling in development. Annu. Rev. Cell Dev. Biol. 14, 59–88 (1998). (10.1146/annurev.cellbio.14.1.59) / Annu. Rev. Cell Dev. Biol. by A Wodarz (1998)
Moon, R. T., Brown, J. D. & Torres, M. WNTs modulate cell fate and behavior during vertebrate development. Trends Genet. 13, 157–162 (1997). (10.1016/S0168-9525(97)01093-7) / Trends Genet. by RT Moon (1997)
Glinka, A. et al. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 391, 357–362 (1998). (10.1038/34848) / Nature by A Glinka (1998)
Hoppler, S., Brown, J. D. & Moon, R. T. Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos. Genes Dev. 10, 2805–2817 (1996). (10.1101/gad.10.21.2805) / Genes Dev. by S Hoppler (1996)
Christian, J. L. & Moon, R. T. Interactions between XWnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus. Genes Dev. 7, 13–28 (1993). (10.1101/gad.7.1.13) / Genes Dev. by JL Christian (1993)
Moon, R. T. et al. Dissecting Wnt signaling pathways and Wnt-sensitive developmental processes through transient misexpression analyses in embryos of Xenopus laevis. Development (suppl.), 85–94 (1993). (10.1242/dev.119.Supplement.85)
van Leeuwen, F., Harryman Samos, C. & Nusse, R. Biological activity of soluble Wingless protein in cultured Drosophila imaginal disc cells. Nature 368, 342–344 (1994). (10.1038/368342a0) / Nature by F van Leeuwen (1994)
Piccolo, S., Sasai, Y., Lu, B. & DeRobertis, E. M. Dorsoventral patterning in Xenopus : inhibition of ventral signals by direct binding of chordin to BMP-4. Cell 86, 589–598 (1996). (10.1016/S0092-8674(00)80132-4) / Cell by S Piccolo (1996)
Zimmerman, L. B., De Jesus-Escobar, J. M. & Harland, R. M. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86, 599–606 (1996). (10.1016/S0092-8674(00)80133-6) / Cell by LB Zimmerman (1996)
Hsu, D. R., Economides, A. N., Wang, X., Eimon, P. M. & Harland, R. M. The Xenopus dorsalizing factor gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol. Cell 1, 673–683 (1998). (10.1016/S1097-2765(00)80067-2) / Mol. Cell by DR Hsu (1998)
Cadigan, K. M., Fish, M. P., Rulifson, E. J. & Nusse, R. Wingless repression of Drosophila frizzled2 expression shapes the Wingless morphogen gradient. Cell 93, 767–777 (1998). (10.1016/S0092-8674(00)81438-5) / Cell by KM Cadigan (1998)
Finch, P. W. et al. Purification and molecular cloning of a secreted frizzled-related antagonist of Wnt signaling. Proc. Natl Acad. Sci. USA 94, 6770–6775 (1997). (10.1073/pnas.94.13.6770) / Proc. Natl Acad. Sci. USA by PW Finch (1997)
Aruffo, A., Stamenkovic, I., Melnick, M., Underhill, C. B. & Seed, B. CD44 is the principal cell surface receptor for hyaluronate. Cell 61, 1303–1313 (1990). (10.1016/0092-8674(90)90694-A) / Cell by A Aruffo (1990)
Rebagliati, M. R., Toyoma, R., Haffter, P. & Dawid, I. B. Cyclops encodes a nodal-related factor involved in midline signaling. Proc. Natl Acad. Sci. USA 95, 9932–9937 (1998). (10.1073/pnas.95.17.9932) / Proc. Natl Acad. Sci. USA by MR Rebagliati (1998)
He, X., Saint-Jeannet, J.-P., Woodgett, J. R., Varmus, H. E. & Dawid, I. B. Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature 374, 617–622 (1995). (10.1038/374617a0) / Nature by X He (1995)
Peifer, M., Orsulic, S., Sweeton, D. & Wieschaus, E. Arole for the Drosophila segment polarity gene armadillo in cell adhesion and cytoskeletal integrity during oogenesis. Development 118, 1191–1207 (1993). (10.1242/dev.118.4.1191) / Development by M Peifer (1993)
Evan, G. I., Lewis, G. K., Ramsay, G. & Bishop, M. J. Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol. 5, 3610–3616 (1985). (10.1128/MCB.5.12.3610) / Mol. Cell. Biol. by GI Evan (1985)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 4:39 a.m.)
Deposited	3 years, 8 months ago (Dec. 1, 2021, 6:22 p.m.)
Indexed	1 week, 2 days ago (Aug. 19, 2025, 6:38 a.m.)
Issued	26 years, 4 months ago (April 1, 1999)
Published	26 years, 4 months ago (April 1, 1999)
Published Print	26 years, 4 months ago (April 1, 1999)

Funders 0

None

BibTeX

@article{Hsieh_1999, title={A new secreted protein that binds to Wnt proteins and inhibits their activites}, volume={398}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/18899}, DOI={10.1038/18899}, number={6726}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Hsieh, Jen-Chih and Kodjabachian, Laurent and Rebbert, Martha L. and Rattner, Amir and Smallwood, Philip M. and Samos, Cynthia Harryman and Nusse, Roel and Dawid, Igor B. and Nathans, Jeremy}, year={1999}, month=apr, pages={431–436} }

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