Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells
10.1038/14058
Crossref journal-article
Springer Science and Business Media LLC
Nature Cell Biology (297)
Bibliography

Rodriguez, A., Regnault, A., Kleijmeer, M., Ricciardi-Castagnoli, P., & Amigorena, S. (1999). Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells. Nature Cell Biology, 1(6), 362–368.

Authors 5
  1. Ana Rodriguez (first)
  2. Armelle Regnault (additional)
  3. Monique Kleijmeer (additional)
  4. Paola Ricciardi-Castagnoli (additional)
  5. Sebastian Amigorena (additional)
References 33 Referenced 430
  1. Pamer, E. & Cresswell, P. Mechanisms of MHC class I-restricted antigen processing. Annu. Rev. Immunol. 16, 323–358 (1998). (10.1146/annurev.immunol.16.1.323) / Annu. Rev. Immunol. by E Pamer (1998)
  2. Watts, C. Capture and processing of exogenous antigens for presentation on MHC molecules . Annu. Rev. Immunol. 15, 821– 850 (1997). (10.1146/annurev.immunol.15.1.821) / Annu. Rev. Immunol. by C Watts (1997)
  3. Germain, R. N. et al. Processing and presentation of endocytically acquired protein antigens by MHC class II and class I molecules. Immunol. Rev. 151, 5–30 (1996). (10.1111/j.1600-065X.1996.tb00701.x) / Immunol. Rev. by RN Germain (1996)
  4. Bevan, M. J. Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J. Exp. Med. 143, 1283–1288 (1976). (10.1084/jem.143.5.1283) / J. Exp. Med. by MJ Bevan (1976)
  5. Huang, A. Y. et al. Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science 264, 961–965 (1994). (10.1126/science.7513904) / Science by AY Huang (1994)
  6. Sigal, L., J., Crotty, S., Andino, R. & Rock, K. L. Cytotoxic T-cell immunity to virus-infected non-hematopoietic cells requires presentation of exogenous antigen. Nature 398, 77– 80 (1999). (10.1038/18038) / Nature by L Sigal (1999)
  7. Carbone, F. R., Kurts, C., Bennett, S. R., Miller, J. F. & Heath, W. R. Cross-presentation: a general mechanism for CTL immunity and tolerance. Immunol. Today 19, 368–373 (1998). (10.1016/S0167-5699(98)01301-2) / Immunol. Today by FR Carbone (1998)
  8. Huang, A. Y., Bruce, A. T., Pardoll, D. M. & Levitsky, H. I. In vivo cross-priming of MHC class I-restricted antigens requires the TAP transporter. Immunity 4, 349– 355 (1996). (10.1016/S1074-7613(00)80248-4) / Immunity by AY Huang (1996)
  9. Banchereau, J. & Steinman, R. M. Dendritic cells and the control of immunity. Nature 392, 245– 252 (1998). (10.1038/32588) / Nature by J Banchereau (1998)
  10. Albert, M. L., Sauter, B. & Bhardwaj, N. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 392, 86–89 (1998). (10.1038/32183) / Nature by ML Albert (1998)
  11. Regnault, A. et al. FcγR-mediated induction of dendritic cell maturation and MHC class I-restricted antigen presentation after immune complex internalization . J. Exp. Med. 189, 371– 380 (1999). (10.1084/jem.189.2.371) / J. Exp. Med. by A Regnault (1999)
  12. Norbury, C. C., Hewlett, L. J., Prescott, A. R., Shastri, N. & Watts, C. Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages. Immunity 3, 783–791 ( 1995). (10.1016/1074-7613(95)90067-5) / Immunity by CC Norbury (1995)
  13. Norbury, C. C., Chambers, B. J., Prescott, A. R., Ljunggren, H. G. & Watts, C. Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells. Eur. J. Immunol. 27, 280–288 (1997). (10.1002/eji.1830270141) / Eur. J. Immunol. by CC Norbury (1997)
  14. Yewdell, J., Norbury, C. & Bennink, J. Mechanisms of exogenous antigen presentation by MHC class I molecules in vitro and in vivo: implications for generating CD8+ T cell responses to infectious agents, tumors, transplants and vaccines . Adv. Immunol. (in the press). (10.1016/S0065-2776(08)60785-3)
  15. Winzler, C. et al. Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures. J. Exp. Med. 185, 317 –328 (1997). (10.1084/jem.185.2.317) / J. Exp. Med. by C Winzler (1997)
  16. Shastri, N. & Gonzalez, F. Endogenous generation and presentation of the ovalbumin peptide/Kb complex to T cells. J. Immunol. 150, 2724–2736 (1993). (10.4049/jimmunol.150.7.2724) / J. Immunol. by N Shastri (1993)
  17. Fenteany, G. et al. Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin. Science 268, 726–731 (1995). (10.1126/science.7732382) / Science by G Fenteany (1995)
  18. Kovacsovics-Bankowski, M., Clark, K., Benacerraf, B. & Rock, K. L. Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc. Natl Acad. Sci. USA 90, 4942–4946 ( 1993). (10.1073/pnas.90.11.4942) / Proc. Natl Acad. Sci. USA by M Kovacsovics-Bankowski (1993)
  19. Shen, Z., Reznikoff, G., Dranoff, G. & Rock, K. L. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. J. Immunol. 158, 2723–2730 (1997). (10.4049/jimmunol.158.6.2723) / J. Immunol. by Z Shen (1997)
  20. Mitchell, D. A., Nair, S. K. & Gilboa, E. Dendritic cell/macrophage precursors capture exogenous antigen for MHC class I presentation by dendritic cells. Eur. J. Immunol. 28, 1923–1933 ( 1998). (10.1002/(SICI)1521-4141(199806)28:06<1923::AID-IMMU1923>3.0.CO;2-9) / Eur. J. Immunol. by DA Mitchell (1998)
  21. Moore, M. W., Carbone, F. R. & Bevan, M. J. Introduction of soluble protein into the class I pathway of antigen processing and presentation. Cell 54, 777–785 (1988). (10.1016/S0092-8674(88)91043-4) / Cell by MW Moore (1988)
  22. Kovacsovics-Bankowski, M. & Rock, K. L. A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science 267, 243–246 ( 1995). (10.1126/science.7809629) / Science by M Kovacsovics-Bankowski (1995)
  23. Reis e Sousa, C. & Germain, R. N. Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis. J. Exp. Med. 182, 841–851 (1995). (10.1084/jem.182.3.841) / J. Exp. Med. by C Reis e Sousa (1995)
  24. Oh, Y. K., Harding, C. V. & Swanson, J. A. The efficiency of antigen delivery from macrophage phagosomes into cytoplasm for MHC class I-restricted antigen presentation . Vaccine 15, 511–518 (1997). (10.1016/S0264-410X(97)00221-1) / Vaccine by YK Oh (1997)
  25. Bachmann, M. F. et al. Dendritic cells process exogenous viral proteins and virus-like particles for class I presentation to CD8+ cytotoxic T lymphocytes. Eur. J. Immunol. 26, 2595–2600 (1996). (10.1002/eji.1830261109) / Eur. J. Immunol. by MF Bachmann (1996)
  26. Rescigno, M. et al. Bacteria-induced neo-biosynthesis, stabilization, and surface expression of functional class I molecules in mouse dendritic cells. Proc. Natl Acad. Sci. USA 95, 5229– 5234 (1998). (10.1073/pnas.95.9.5229) / Proc. Natl Acad. Sci. USA by M Rescigno (1998)
  27. Prina, E., Lang, T., Glaichenhaus, N. & Antoine, J.-C. Presentation of the protective parasite antigen LACK by Leishmania-infected macrophages. J. Immunol. 156, 4318– 4327 (1996). (10.4049/jimmunol.156.11.4318) / J. Immunol. by E Prina (1996)
  28. Sanderson, S. & Shastri, N. LacZ inducible, antigen/MHC-specific T cell hybrids. Int. Immunol. 6, 369– 376 (1994). (10.1093/intimm/6.3.369) / Int. Immunol. by S Sanderson (1994)
  29. Raposo, G., Kleijmeer, M. J., Posthuma, G., Slot, J. W. & Geuze, H. J. in Weir’s Handbook of Exp. Immunol. 5th edn Vol. 4 Ch. 208 (eds Herzenberg, L. A., Weir, D., Herzenberg, L. A. & Blackwell, C.) 1–11 (Blackwell Science, Cambridge, MA, 1997). / Weir’s Handbook of Exp. Immunol. by G Raposo (1997)
  30. Drake, J. R., Repasky, E. A. & Bankert, R. B. Endocytosis of antigen, anti-idiotype, and anti-immunoglobulin antibodies and receptor re-expression by murine B cells. J. Immunol. 143, 1768–1776 ( 1989). (10.4049/jimmunol.143.6.1768) / J. Immunol. by JR Drake (1989)
  31. Green, S. A., Zimmer, K. P., Griffiths, G. & Mellman, I. Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins. J. Cell Biol. 105, 1227–1240 (1987). (10.1083/jcb.105.3.1227) / J. Cell Biol. by SA Green (1987)
  32. Rodriguez, A., Webster, P., Ortego, J. & Andrews, N. W. Lysosomes behave as Ca2+-regulated exocytic vesicles in fibroblasts and epithelial cells. J. Cell Biol. 137, 93– 104 (1997). (10.1083/jcb.137.1.93) / J. Cell Biol. by A Rodriguez (1997)
  33. Press, B., Feng, Y., Hoflack, B. & Wandinger-Ness, A. Mutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartment. J. Cell Biol. 140, 1075–1089 ( 1998). (10.1083/jcb.140.5.1075) / J. Cell Biol. by B Press (1998)
Dates
Type When
Created 23 years, 1 month ago (July 26, 2002, 4:47 a.m.)
Deposited 2 years, 4 months ago (April 20, 2023, 7:54 p.m.)
Indexed 1 month ago (Aug. 2, 2025, 12:08 a.m.)
Issued 25 years, 11 months ago (Sept. 16, 1999)
Published 25 years, 11 months ago (Sept. 16, 1999)
Published Online 25 years, 11 months ago (Sept. 16, 1999)
Published Print 25 years, 11 months ago (Oct. 1, 1999)
Funders 0

None

@article{Rodriguez_1999, title={Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells}, volume={1}, ISSN={1476-4679}, url={http://dx.doi.org/10.1038/14058}, DOI={10.1038/14058}, number={6}, journal={Nature Cell Biology}, publisher={Springer Science and Business Media LLC}, author={Rodriguez, Ana and Regnault, Armelle and Kleijmeer, Monique and Ricciardi-Castagnoli, Paola and Amigorena, Sebastian}, year={1999}, month=sep, pages={362–368} }