Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2
10.1038/12491
Crossref journal-article
Springer Science and Business Media LLC
Nature Medicine (297)
Bibliography

Girod, A., Ried, M., Wobus, C., Lahm, H., Leike, K., Kleinschmidt, J., Deléage, G., & Hallek, M. (1999). Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2. Nature Medicine, 5(9), 1052–1056.

Authors 8
  1. Anne Girod (first)
  2. Martin Ried (additional)
  3. Christiane Wobus (additional)
  4. Harald Lahm (additional)
  5. Kristin Leike (additional)
  6. Jürgen Kleinschmidt (additional)
  7. Gilbert Deléage (additional)
  8. Michael Hallek (additional)
References 24 Referenced 218
  1. Kotin, R.M. Prospects for the use of adeno-associated virus as a vector for human gene therapy. Hum. Gene Ther. 5, 793– 801 (1994). (10.1089/hum.1994.5.7-793) / Hum. Gene Ther. by RM Kotin (1994)
  2. Hallek, M. et al. Recombinant adeno-associated virus vectors. IDrugs 1, 561–573 ( 1998). / IDrugs by M Hallek (1998)
  3. Mizukami, H., Young, N.S. & Brown, K.E. Adeno-associated virus type 2 binds to a 150-kilodalton cell membrane glycoprotein. Virology 217, 124–130 (1996). (10.1006/viro.1996.0099) / Virology by H Mizukami (1996)
  4. Summerford, C. & Samulski, R.J. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. J. Virol. 72, 1438–1445 (1998). (10.1128/JVI.72.2.1438-1445.1998) / J. Virol by C Summerford (1998)
  5. Summerford, C., Bartlett, J.S. & Samulski, R.J. αVβ5 integrin: a co-receptor for adeno-associated virus type 2 infection. Nature Med. 5, 78 –82 (1999). (10.1038/4768) / Nature Med. by C Summerford (1999)
  6. Qing, K. et al. Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2. Nature Med. 5, 71–77 (1999). (10.1038/4758) / Nature Med. by K Qing (1999)
  7. Hermonat, P.L., Labow, M.A., Wright, R., Berns, K.I. & Muzyczka, N. Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants. J. Virol. 51, 329–339 ( 1984). (10.1128/JVI.51.2.329-339.1984) / J. Virol. by PL Hermonat (1984)
  8. Tratschin, J.D., Miller, I.L. & Carter, B.J. Genetic analysis of adeno-associated virus: properties of deletion mutants constructed in vitro and evidence for an adeno-associated virus replication function. J. Virol. 51, 611–619 (1984). (10.1128/JVI.51.3.611-619.1984) / J. Virol. by JD Tratschin (1984)
  9. Ruffing, M., Heid, H. & Kleinschmidt, J.A. Mutations in the carboxy terminus of adeno-associated virus 2 capsid proteins affect viral infectivity: lack of an RGD integrin-binding motif. J. Gen. Virol. 75, 3385– 3392 (1994). (10.1099/0022-1317-75-12-3385) / J. Gen. Virol. by M Ruffing (1994)
  10. Tsao, J. et al. The three-dimensional structure of canine parvovirus and its functional implications. Science 251, 1456 –1464 (1991). (10.1126/science.2006420) / Science by J Tsao (1991)
  11. Geourjon, C. & Deléage, G. OPM: a self-optimized method for protein secondary structure prediction. Protein Eng. 7, 157–164 (1994). (10.1093/protein/7.2.157) / Protein Eng. by C Geourjon (1994)
  12. Thompson, J.D., Higgins, D.G. & Gibson, T.J. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Research 22, 4673–4680 ( 1994). (10.1093/nar/22.22.4673) / Nucleic Acids Research by JD Thompson (1994)
  13. Aumailley, M., Gerl, M., Sonnenberg, A., Deutzmann, R. & Timpl, R. Identification of the Arg-Gly-Asp sequence in laminin A chain as a latent cell-binding site being exposed in fragment P1. FEBS Lett. 262, 82–86 ( 1990). (10.1016/0014-5793(90)80159-G) / FEBS Lett. by M Aumailley (1990)
  14. White, J.M. Integrins as virus receptors. Curr. Biol. 3, 596–599 (1993). (10.1016/0960-9822(93)90007-B) / Curr. Biol. by JM White (1993)
  15. Valsesia-Wittmann, S. et al. Modifications in the binding domain of avian retrovirus envelope protein to redirect the host range of retroviral vectors. J. Virol. 68, 4609–4619 (1994). (10.1128/JVI.68.7.4609-4619.1994) / J. Virol. by S Valsesia-Wittmann (1994)
  16. Wistuba, A., Kern, A., Weger, S., Grimm, D. & Kleinschmidt, J.A. Subcellular compartimentalization of adeno-associated virus type 2 assembly. J. Virol. 71, 1341 –1352 (1997). (10.1128/JVI.71.2.1341-1352.1997) / J. Virol. by A Wistuba (1997)
  17. Stewart, P.L. et al. Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralization. EMBO J. 16, 1189–1198 (1997). (10.1093/emboj/16.6.1189) / EMBO J. by PL Stewart (1997)
  18. Yang, Q. et al. Development of novel cell surface CD34-targeted recombinant adenoassociated virus vectors for gene therapy. Hum. Gene Ther. 9, 1929–1937 ( 1998). (10.1089/hum.1998.9.13-1929) / Hum. Gene Ther. by Q Yang (1998)
  19. Bartlett, J.S., Kleinschmidt, J.A., Boucher, R.C. & Samulski, R.J. Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'γ)2 antibody. Nat. Biotech. 17, 181–186 ( 1999). (10.1038/6185) / Nat. Biotech. by JS Bartlett (1999)
  20. Smith, T.F. & Waterman, M.S. Identification of common molecular subsequences. J. Mol. Biol. 147, 195– 197 (1981). (10.1016/0022-2836(81)90087-5) / J. Mol. Biol. by TF Smith (1981)
  21. Kabsch, W. & Sander, C. Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. Biopolymers 22, 2577–2637 (1983). (10.1002/bip.360221211) / Biopolymers by W Kabsch (1983)
  22. Samulski, R.J., Chang, L.S. & Shenk, T. A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication. J. Virol. 61, 3096– 3101 (1987). (10.1128/JVI.61.10.3096-3101.1987) / J. Virol. by RJ Samulski (1987)
  23. Chiorini, J.A. et al. High-efficiency transfer of the T cell co-stimulatory molecule B7-2 to lymphoid cells using high-titer recombinant adeno-associated virus vectors. Hum. Gene Ther. 6, 1531– 1541 (1995). (10.1089/hum.1995.6.12-1531) / Hum. Gene Ther. by JA Chiorini (1995)
  24. Carrel, S., Sordat, B. & Merenda, C. Establishment of a cell line (Co-115) from a human colon carcinoma transplanted into nude mice. Cancer Res. 36, 3978–3984 (1976). / Cancer Res. by S Carrel (1976)
Dates
Type When
Created 23 years, 1 month ago (July 26, 2002, 4:43 a.m.)
Deposited 3 years, 9 months ago (Dec. 1, 2021, 3:07 p.m.)
Indexed 5 days, 22 hours ago (Aug. 31, 2025, 6:12 a.m.)
Issued 26 years ago (Sept. 1, 1999)
Published 26 years ago (Sept. 1, 1999)
Published Print 26 years ago (Sept. 1, 1999)
Funders 0

None

@article{Girod_1999, title={Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2}, volume={5}, ISSN={1546-170X}, url={http://dx.doi.org/10.1038/12491}, DOI={10.1038/12491}, number={9}, journal={Nature Medicine}, publisher={Springer Science and Business Media LLC}, author={Girod, Anne and Ried, Martin and Wobus, Christiane and Lahm, Harald and Leike, Kristin and Kleinschmidt, Jürgen and Deléage, Gilbert and Hallek, Michael}, year={1999}, month=sep, pages={1052–1056} }