DOI: 10.1038/10552. Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis

Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis

10.1038/10552

Crossref journal-article

Springer Science and Business Media LLC

Nature Medicine (297)

Bibliography

Moore, R. J., Owens, D. M., Stamp, G., Arnott, C., Burke, F., East, N., Holdsworth, H., Turner, L., Rollins, B., Pasparakis, M., Kollias, G., & Balkwill, F. (1999). Mice deficient in tumor necrosis factor-Î± are resistant to skin carcinogenesis. Nature Medicine, 5(7), 828â831.

Authors 12

Robert J. Moore (first)
David M. Owens (additional)
Gordon Stamp (additional)
Caroline Arnott (additional)
Frances Burke (additional)
Nick East (additional)
Hazel Holdsworth (additional)
Lynn Turner (additional)
Barrett Rollins (additional)
Manolis Pasparakis (additional)
George Kollias (additional)
Frances Balkwill (additional)

References 21 Referenced 659

Correa, P. Human gastric carcinogenesis: a multistep and multifactorial process–First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res. 52, 6735–6740 (1992). / Cancer Res. by P Correa (1992)
Palli, D. et al. General and cancer specific mortality of a population based cohort of patients with inflammatory bowel disease: the Florence Study. Gut 42, 175–179 ( 1998). (10.1136/gut.42.2.175) / Gut by D Palli (1998)
Brown, K., and Balmain, A. Transgenic mice and squamous multistage skin carcinogenesis. Cancer Metastasis Rev. 14, 113–124 (1995). (10.1007/BF00665795) / Cancer Metastasis Rev. by K Brown (1995)
Arbeit, J.A. Transgenic models of epidermal neoplasia and multistage carcinogenesis. Cancer Surv. 26, 7–34 ( 1996). / Cancer Surv. by JA Arbeit (1996)
Pasparakis, M., Alexopoulou, L., Episkopou, V. & Kollias, G. Immune and inflammatory responses in TNF-α deficient mice: A critical requirement for TNF-α in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centres, and in the maturation of the humoral immune response. J. Exp. Med. 184, 1397–1411 (1996). (10.1084/jem.184.4.1397) / J. Exp. Med. by M Pasparakis (1996)
Pasparakis, M. et al. Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor. Proc. Natl. Acad. Sci. USA 94, 6319–6323 ( 1997). (10.1073/pnas.94.12.6319) / Proc. Natl. Acad. Sci. USA by M Pasparakis (1997)
Fischer S.M. et al. Correlation of phorbol ester promotion in the resistant C57BL/6J mouse with sustained hyperplasia but not ornithine decarboxylase or protein kinase C. Cancer Res. 49, 6693– 6699 (1989). / Cancer Res. by SM Fischer (1989)
Reiners, J.J., Nesnow, S.,& Slaga, T.J. Murine susceptibilty to two-stage skin carcinogenesis is influenced by the agent used for promotion. Carcinogenesis 5, 301–307 (1984). (10.1093/carcin/5.3.301) / Carcinogenesis by JJ Reiners (1984)
Bradley P.P., Priebat, D.A., Christensen, R.D. & Rothstein, G. Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 78, 206–209 (1982). (10.1111/1523-1747.ep12506462) / J. Invest. Dermatol. by PP Bradley (1982)
Lu, B. et al. Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J. Exp. Med. 16, 601–608 ( 1998). (10.1084/jem.187.4.601) / J. Exp. Med. by B Lu (1998)
Komori, A. et al. Tumor necrosis factor acts as a tumor promoter in BALB/3T3 transformation. Cancer Res. 53, 1982– 1985 (1993). / Cancer Res. by A Komori (1993)
Suganuma, M. et al. A new process of cancer prevention mediated through inhibition of tumor necrosis factor α expression. Cancer Res. 56, 3711–3715 (1996). / Cancer Res. by M Suganuma (1996)
Robertson, F.K. Ross, M.S., Tober, K.L., Long, B.W. & Oberyszyn, T.M. Inhibition of pro-inflammatory cytokine gene expression and papilloma growth during murine multistage carcinogenesis by pentoxifyline. Carcinogenesis 17, 1719– 1728 (1996). (10.1093/carcin/17.8.1719) / Carcinogenesis by FK Robertson (1996)
Naylor, MS, Stamp, G.W., Foulkes, W.D., Eccles, D., & Balkwill, F.R. Tumor necrosis factor and its receptors–potential in disease progression. J. Clin. Invest. 91, 2194–2206 ( 1993). (10.1172/JCI116446) / J. Clin. Invest. by MS Naylor (1993)
Negus, R.P.M., Turner, L., Burke, F. & Balkwill, F.R. Hypoxia down-regulates MCP-1 expression: implications for macrophage distribution in tumors. J. Leucocyte Biol. 63, 758–765 (1998). (10.1002/jlb.63.6.758) / J. Leucocyte Biol. by RPM Negus (1998)
Malik, S.T.A., Naylor, S., East, N., Oliff, A. & Balkwill, FR. Cells secreting tumor necrosis factor show enhanced metastasis in nude mice. Eur. J. Cancer 26, 1031–1034 (1990). (10.1016/0277-5379(90)90044-T) / Eur. J. Cancer by STA Malik (1990)
Orosz, P. et al. Promotion of experimental liver metastasis by tumor necrosis factor. Int. J. Cancer 60, 867– 871 (1995). (10.1002/ijc.2910600624) / Int. J. Cancer by P Orosz (1995)
Eggermont, A.M.M. et al. Isolated limb perfusion with high dose tumor necrosis factor-α in combination with interferon-gamma and melphalan for irresectable extremity soft tissue sarcomas: A multicentre trial. J. Clin. Oncol. 14, 2653–2665 (1996). (10.1200/JCO.1996.14.10.2653) / J. Clin. Oncol. by AMM Eggermont (1996)
Feldmann, M., Elliott, M.J., Woody, J.N. & Maini, R.N. Anti-tumor necrosis factor-alpha therapy of rheumatoid arthritis. Adv. Immunol. 64, 283–350 (1997). (10.1016/S0065-2776(08)60891-3) / Adv. Immunol. by M Feldmann (1997)
Wilson, A.G. et al. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc. Natl. Acad. Sci. USA 94, 3195–3197 ( 1997). (10.1073/pnas.94.7.3195) / Proc. Natl. Acad. Sci. USA by AG Wilson (1997)
Warzocha, K. et al. Genetic polymorphisms in the tumor necrosis factor locus influence non-Hodgkin's lymphoma outcome. Blood 91, 3574–3581 (1998). (10.1182/blood.V91.10.3574) / Blood by K Warzocha (1998)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 4:43 a.m.)
Deposited	3 years, 9 months ago (Dec. 1, 2021, 3:46 p.m.)
Indexed	12 minutes ago (Sept. 3, 2025, 12:22 a.m.)
Issued	26 years, 2 months ago (July 1, 1999)
Published	26 years, 2 months ago (July 1, 1999)
Published Print	26 years, 2 months ago (July 1, 1999)

Funders 0

None

BibTeX

@article{Moore_1999, title={Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis}, volume={5}, ISSN={1546-170X}, url={http://dx.doi.org/10.1038/10552}, DOI={10.1038/10552}, number={7}, journal={Nature Medicine}, publisher={Springer Science and Business Media LLC}, author={Moore, Robert J. and Owens, David M. and Stamp, Gordon and Arnott, Caroline and Burke, Frances and East, Nick and Holdsworth, Hazel and Turner, Lynn and Rollins, Barrett and Pasparakis, Manolis and Kollias, George and Balkwill, Frances}, year={1999}, month=jul, pages={828–831} }

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