DOI: 10.1034/j.1600-0854.2002.030303.x. Type IVB Secretion by Intracellular Pathogens

Type IVB Secretion by Intracellular Pathogens

10.1034/j.1600-0854.2002.030303.x

Crossref journal-article

Wiley

Traffic (311)

Abstract

A growing number of pathogens are being found to possess specialized secretion systems which they use in various ways to subvert host defenses. One class, called type IV, are defined as having homology to the conjugal transfer systems of naturally occurring plasmids. It has been proposed that pathogens with type IV secretion systems have acquired and adapted the conjugal transfer systems of plasmids and now use them to export toxins. Several well‐characterized intracellular pathogens, including Legionella pneumophila, Coxiella burnetii, Brucella abortus, and Rickettsia prowazekii, contain type IV systems which are known or suspected to be of critical importance in their ability to cause disease. Specifically, these systems are believed to be the key factors determining intracellular fate, and thus the ability to replicate and cause disease.

Bibliography

Sexton, J. A., & Vogel, J. P. (2002). Type IVB Secretion by Intracellular Pathogens. Traffic, 3(3), 178â185. Portico.

Authors 2

Jessica A. Sexton (first)
Joseph P. Vogel (additional)

References 59 Referenced 139

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Dates

Type	When
Created	22 years, 5 months ago (March 12, 2003, 5:13 p.m.)
Deposited	1 year, 10 months ago (Oct. 13, 2023, 7:31 p.m.)
Indexed	2 days ago (Aug. 29, 2025, 6:18 a.m.)
Issued	23 years, 5 months ago (March 1, 2002)
Published	23 years, 5 months ago (March 1, 2002)
Published Online	23 years, 5 months ago (March 18, 2002)
Published Print	23 years, 5 months ago (March 1, 2002)

Funders 0

None

BibTeX

@article{Sexton_2002, title={Type IVB Secretion by Intracellular Pathogens}, volume={3}, ISSN={1600-0854}, url={http://dx.doi.org/10.1034/j.1600-0854.2002.030303.x}, DOI={10.1034/j.1600-0854.2002.030303.x}, number={3}, journal={Traffic}, publisher={Wiley}, author={Sexton, Jessica A. and Vogel, Joseph P.}, year={2002}, month=mar, pages={178–185} }

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