DOI: 10.1023/a:1020444330011. Rate-Limited Steps of Human Oral Absorption and QSAR Studies

Rate-Limited Steps of Human Oral Absorption and QSAR Studies

10.1023/a:1020444330011

Crossref journal-article

Springer Science and Business Media LLC

Pharmaceutical Research (297)

Bibliography

Zhao, Y. H., Abraham, M. H., Le, J., Hersey, A., Luscombe, C. N., Beck, G., Sherborne, B., & Cooper, I. (2002). Rate-Limited Steps of Human Oral Absorption and QSAR Studies. Pharmaceutical Research, 19(10), 1446â1457.

Authors 8

Yuan H. Zhao (first)
Michael H. Abraham (additional)
Joelle Le (additional)
Anne Hersey (additional)
Chris N. Luscombe (additional)
Gordon Beck (additional)
Brad Sherborne (additional)
Ian Cooper (additional)

References 29 Referenced 596

Y. C. Martin, E. Kutter, and V. Austel. Modern Drug Research-Paths to Better and Safer Drugs. Dekker, New York, 1989. / Modern Drug Research-Paths to Better and Safer Drugs by Y. C. Martin (1989)
P. O. Gubbins and K. E. Bertch. Drug absorption in gastrointestinal disease and surgery. Clinical pharmacokinetic and therapeutic implications. Clin.Pharmacokinet. 21:431-447 (1991). (10.2165/00003088-199121060-00004) / Clin. Pharmacokinet. by P. O. Gubbins (1991)
M. Gibaldi. Limitations of classical theories of drug absorption. In: Prescott and Nimmo (eds.), Drug Absorption: Proceeding of the Edinburgh International Conference, ADIS Press, Auckland, 1979 pp. 1-5. / Drug Absorption: Proceeding of the Edinburgh International Conference by M. Gibaldi (1979)
G. S. Banker and V. E. Sharma. Advances in controlled gastrointestinal absorption. In: Prescott and Nimmo (eds.), Drug Absorption: Proceeding of the Edinburgh International Conference, ADIS Press, Auckland, 1979 pp. 194-204. / Drug Absorption: Proceeding of the Edinburgh International Conference by G. S. Banker (1979)
J. B. Dressman, G. L. Amidon, and D. Fleisher. Absorption potential: estimating the fraction absorbed for orally-administered compounds. J.Pharm.Sci. 74:588-589 (1985). (10.1002/jps.2600740523) / J. Pharm. Sci. by J. B. Dressman (1985)
J. B. Dressman, G. L. Amidon, C. Reppas, and V. P. Shah. Dissolution testing as a prognostic tool for oral drug absorption: immediate dosage forms. Pharm.Res. 15:11-22 (1998). (10.1023/A:1011984216775) / Pharm. Res. by J. B. Dressman (1998)
J. C. Dearden. Molecular Structure and Drug Transport.Comprehensive Medicinal Chemistry. C. Hansch (ed.). Pegamar, Oxford, 1990 pp. 375-411. / Molecular Structure and Drug Transport.Comprehensive Medicinal Chemistry by J. C. Dearden (1990)
R. W. Foster. Basic Pharmacology. Reed Educational & Professional Publishing Ltd, Great Britain, 1996. / Basic Pharmacology by R. W. Foster (1996)
L. S. Schanker, D. J. Tocco, B. B. Brodie, and C. A. M. Hogben. Absorption of drugs from the rat small intestine. J.Pharmacol.Exp.Ther. 123:81-88 (1958). (10.1016/S0022-3565(25)12018-1) / J. Pharmacol. Exp. Ther. by L. S. Schanker (1958)
J. T. Dolusio, N. F. Billups, L. W. Dittert, E. T. Sugita, and J. V. Swintosky. Drug absorption I: An in situ rat gut technique yielding realistic absorption rates. J.Pharm.Sci. 58:1196-1200 (1969). (10.1002/jps.2600581006) / J. Pharm. Sci. by J. T. Dolusio (1969)
S. Yee. In vitro permeability across caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man-fact or myth. Pharm.Res. 14:763-766 (1997). (10.1023/A:1012102522787) / Pharm. Res. by S. Yee (1997)
Y. H. Zhao, J. Le, M. H. Abraham, A. Hersey, P. J. Eddershaw, C. N. Luscombe, D. Butina, G. Beck, B. Sherborne, I. Cooper, and J. A. Platts. Evaluation of human intestinal absorption data for use in QSAR studies and a quantitative relationship obtained with the Abraham descriptors. J.Pharm.Sci. 90:749-784 (2001). (10.1002/jps.1031) / J. Pharm. Sci. by Y. H. Zhao (2001)
C. A. Lipinski, F. Lombardo, B. W. Dominy, and P. J. Feeney. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv.Drug Deliv.Rev. 23:3-25 (1997). (10.1016/S0169-409X(96)00423-1) / Adv. Drug Deliv. Rev. by C. A. Lipinski (1997)
O. A. Raevsky, V. I. Fetisov, E. P. Trepalina, J. W. McFarland, and K. J. Schaper. Quantitative estimation of drug absorption in humans for passively transported compounds on the basis of their physical-chemical parameters. Quant.Struct.Act.Relat. 19:366-374 (2000). (10.1002/1521-3838(200010)19:4<366::AID-QSAR366>3.0.CO;2-E) / Quant. Struct. Act. Relat. by O. A. Raevsky (2000)
D. E. Clark. Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 1. Prediction of intestinal absorption. J.Pharm.Sci. 88:807-814 (1999). (10.1021/js9804011) / J. Pharm. Sci. by D. E. Clark (1999)
K. Palm, P. Stenberg, K. Luthman, and P. Artursson. Polar molecular surface properties predict and the intestinal absorption of drugs in humans. Pharm.Res. 14:568-571 (1997). (10.1023/A:1012188625088) / Pharm. Res. by K. Palm (1997)
M. D. Wessel, P. C. Jurs, J. W. Tolan, and S. M. Muskal. Prediction of human intestinal absorption of drugs from molecular structure. J.Chem.Inf.Comput.Sci. 38:726-735 (1998). (10.1021/ci980029a) / J. Chem. Inf. Comput. Sci. by M. D. Wessel (1998)
S. D. Krämer. Absorption prediction from physicochemical parameters. PSTT 2:36-42 (1999). / PSTT by S. D. Krämer (1999)
K. J. Schaper. Absorption of ionizable drugs: nonlinear dependence on logP, pKa and pH-quantitative relationships. Quant.Struct.Act.Relat. 1:13-27 (1982). (10.1002/qsar.19820010104) / Quant. Struct. Act. Relat. by K. J. Schaper (1982)
M. H. Abraham, H. S. Chadha, G. S. Whiting, and R. C. Mitchell. Hydrogen bonding. 32. An analysis of water-octanol and wateralkane partitioning and the delta log P parameter of Seiler. J.Pharm.Sci. 83:1085-1100 (1994). (10.1002/jps.2600830806) / J. Pharm. Sci. by M. H. Abraham (1994)
J. B. Dressman and D. Fleisher. Mixing-tank model for predicting dissolution rate control of oral absorption. J.Pharm.Sci. 75:109-116 (1986). (10.1002/jps.2600750202) / J. Pharm. Sci. by J. B. Dressman (1986)
B. Balon, B. U. Riebesehl, and B. W. Müller. Drug liposome partitioning as a tool for the prediction of human passive intestinal absorption. Pharm.Res. 16:890-896 (1999). (10.1023/A:1018882221008) / Pharm. Res. by B. Balon (1999)
J. A. Platts, M. H. Abraham, A. Hersey, and D. Butina. Estimation of molecular linear free energy relationship descriptors by a group contribution approach. 2. Prediction of partition coefficients. J.Chem.Inf.Comp.Sci. 40:71-80 (2000). (10.1021/ci990427t) / J. Chem. Inf. Comp. Sci. by J. A. Platts (2000)
W. K. Sietsema. The absorption oral bioavailability of selected drugs. Int.J.Clin.Pharmacol.Ther.Toxicol. 27:179-211 (1989). / Int. J. Clin. Pharmacol. Ther. Toxicol. by W. K. Sietsema (1989)
P. Michael Conn and G. F. Gebhart. Essentials of Pharmacology. F.A. Davis Company, Philadelphia, Pennsylvania, 1989. / Essentials of Pharmacology by P. Michael Conn (1989)
T. B. Binns. Absorption and Distribution of Drugs. E. & S. Livingstone LTD., Edinburgh and London, 1964. / Absorption and Distribution of Drugs by T. B. Binns (1964)
M. Rowland and T. N. Tozer. Clinical Pharmacokinetics: concepts and Applications. Lea & Febiger, Philadelphia, Pennsylvania, 1995. / Clinical Pharmacokinetics: concepts and Applications by M. Rowland (1995)
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G. L. Amidon, H. Lennernas, V. P. Shah, and J. R. Crison. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm.Res. 12:413-420 (1995). (10.1023/A:1016212804288) / Pharm. Res. by G. L. Amidon (1995)

Dates

Type	When
Created	22 years, 5 months ago (March 18, 2003, 8:55 a.m.)
Deposited	4 weeks, 2 days ago (Aug. 1, 2025, 4:51 a.m.)
Indexed	1 week, 5 days ago (Aug. 19, 2025, 6:44 a.m.)
Issued	22 years, 10 months ago (Oct. 1, 2002)
Published	22 years, 10 months ago (Oct. 1, 2002)
Published Print	22 years, 10 months ago (Oct. 1, 2002)

Funders 0

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BibTeX

@article{Zhao_2002, title={Rate-Limited Steps of Human Oral Absorption and QSAR Studies}, volume={19}, ISSN={1573-904X}, url={http://dx.doi.org/10.1023/a:1020444330011}, DOI={10.1023/a:1020444330011}, number={10}, journal={Pharmaceutical Research}, publisher={Springer Science and Business Media LLC}, author={Zhao, Yuan H. and Abraham, Michael H. and Le, Joelle and Hersey, Anne and Luscombe, Chris N. and Beck, Gordon and Sherborne, Brad and Cooper, Ian}, year={2002}, month=oct, pages={1446–1457} }

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