DOI: 10.1021/ja954131p. Evidence for the Importance of High-Valent FeO and of a Diketone in the Molecular Mechanism of Action of Antimalarial Trioxane Analogs of Artemisinin

Evidence for the Importance of High-Valent FeO and of a Diketone in the Molecular Mechanism of Action of Antimalarial Trioxane Analogs of Artemisinin

10.1021/ja954131p

Crossref journal-article

American Chemical Society (ACS)

Journal of the American Chemical Society (316)

Bibliography

Posner, G. H., Park, S. B., GonzÃ¡lez, L., Wang, D., Cumming, J. N., Klinedinst, D., Shapiro, T. A., & Bachi, M. D. (1996). Evidence for the Importance of High-Valent FeO and of a Diketone in the Molecular Mechanism of Action of Antimalarial Trioxane Analogs of Artemisinin. Journal of the American Chemical Society, 118(14), 3537â3538.

Authors 8

Gary H. Posner (first)
Sheldon B. Park (additional)
Lluïsa González (additional)
Dasong Wang (additional)
Jared N. Cumming (additional)
Donna Klinedinst (additional)
Theresa A. Shapiro (additional)
Mario D. Bachi (additional)

References 23 Referenced 83

10.1126/science.3887571 / Science by For (1985)
10.1016/S0040-4020(01)80810-3 / Tetrahedron by Avery M. A. (1994)
{'key': 'ja954131pb00003/ja954131pb00003_1', 'volume-title': 'Switzerland', 'author': 'Free Radicals', 'year': '1993'} / Switzerland by Free Radicals (1993)
10.1128/AAC.37.5.1108 / Antimicrob. Agents Chemother. by Meshnick S. R. (1993)
10.1016/0166-6851(94)90014-0 / Mol. Biochem. Parsitol. by Hong Y.-L. (1994)
10.1021/jm00013a001 / J. Med. Chem. by Posner G. H. (1995)
10.1021/ja00126a042 / J. Am. Chem. Soc. by Posner G. H. (1995)
10.1016/0040-4039(90)80167-K / Tetrahedron Lett. by Curran D. P. (1990)
10.1021/ja00866a026 / J. Am. Chem. Soc. by Kochi J. K. (1962)
{'key': 'ja954131pb00009/ja954131pb00009_2', 'volume-title': 'Free Radical Chain Reactions in Organic Synthesis', 'author': 'Motherwell W. B.', 'year': '1992'} / Free Radical Chain Reactions in Organic Synthesis by Motherwell W. B. (1992)
10.1039/P29780000145 / J. Chem. Soc., Perkin Trans. 2 by Davies A. G. (1978)
Approximate homolytic C−H bond dissociation energies (kcal/mol) are as follows: primary, 98; secondary, 94.5; tertiary, 91; PhCH2−H, 85; see: Solomons, T. W. G.OrganicChemistry, 5th ed.; John Wiley & Sons: New York, 1992, p 266.
10.1021/jo00359a022 / J. Org. Chem. by Ceccherelli P. (1986)
10.1002/hlca.19930760804 / Helv. Chim. Acta by Jefford C. W. (1993)
10.1002/hc.520060205 / Heteroat. Chem. by Posner G. H. (1995)
10.1097/00005072-199207000-00007 / J. Neuropathol. Exp. Neurol. by Pyle S. J. (1992)
10.1016/0006-2952(93)90425-V / Biochem. Pharmacol. by Yang Y.-Z. (1993)
{'key': 'ja954131pb00015/ja954131pb00015_2', 'first-page': '757', 'volume': '123', 'author': 'Asawamahasakda W.', 'year': '1994', 'journal-title': 'J. Lab. Clin. Med.'} / J. Lab. Clin. Med. by Asawamahasakda W. (1994)
10.1128/AAC.38.8.1854 / Antimicrob. Agents Chemother. by Asawamahasakda W. (1994)
10.1023/A:1018943329109 / Pharm. Res. (1993)
10.1021/ja00107a026 / J. Am. Chem. Soc. (1995)
10.1016/0040-4039(95)02329-1 / Tetrahedron Lett. by Posner G. H. (1996)
10.1016/0040-4039(95)02142-6 / Tetrahedron Lett. (1996)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 1:45 a.m.)
Deposited	2 years, 5 months ago (March 30, 2023, 9:55 a.m.)
Indexed	1 year, 10 months ago (Nov. 2, 2023, 10:22 a.m.)
Issued	29 years, 8 months ago (Jan. 1, 1996)
Published	29 years, 8 months ago (Jan. 1, 1996)
Published Online	29 years, 4 months ago (April 10, 1996)
Published Print	29 years, 8 months ago (Jan. 1, 1996)

Funders 0

None

BibTeX

@article{Posner_1996, title={Evidence for the Importance of High-Valent FeO and of a Diketone in the Molecular Mechanism of Action of Antimalarial Trioxane Analogs of Artemisinin}, volume={118}, ISSN={1520-5126}, url={http://dx.doi.org/10.1021/ja954131p}, DOI={10.1021/ja954131p}, number={14}, journal={Journal of the American Chemical Society}, publisher={American Chemical Society (ACS)}, author={Posner, Gary H. and Park, Sheldon B. and González, Lluïsa and Wang, Dasong and Cumming, Jared N. and Klinedinst, Donna and Shapiro, Theresa A. and Bachi, Mario D.}, year={1996}, month=jan, pages={3537–3538} }

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