DOI: 10.1021/ja052279v. Using Microfluidics to Observe the Effect of Mixing on Nucleation of Protein Crystals

Using Microfluidics to Observe the Effect of Mixing on Nucleation of Protein Crystals

10.1021/ja052279v

Crossref journal-article

American Chemical Society (ACS)

Journal of the American Chemical Society (316)

Bibliography

Chen, D. L., Gerdts, C. J., & Ismagilov, R. F. (2005). Using Microfluidics to Observe the Effect of Mixing on Nucleation of Protein Crystals. Journal of the American Chemical Society, 127(27), 9672â9673.

Authors 3

Delai L. Chen (first)
Cory J. Gerdts (additional)
Rustem F. Ismagilov (additional)

References 14 Referenced 132

{'key': 'ja052279vb00001/ja052279vb00001_1', 'volume-title': 'Crystallization of biological macromolecules', 'author': 'McPherson A.', 'year': '1999'} / Crystallization of biological macromolecules by McPherson A. (1999)
10.1073/pnas.110000497 / Proc. Natl. Acad. Sci. U.S.A. by Galkin O. (2000)
10.1016/S1047-8477(03)00034-0 / J. Struct. Biol. by Chernov A. A. (2003)
{'key': 'ja052279vb00004/ja052279vb00004_1', 'first-page': '528', 'volume': '27', 'author': 'Chen P. C.', 'year': '2004', 'journal-title': 'Chem. Eng. Technol.'} / Chem. Eng. Technol. by Chen P. C. (2004)
{'key': 'ja052279vb00005/ja052279vb00005_1', 'first-page': '355', 'volume': '354', 'author': 'Suga S.', 'year': '2003', 'journal-title': 'Chem. Commun.'} / Chem. Commun. by Suga S. (2003)
10.1002/anie.200390204 / Angew. Chem., Int. Ed. by Song H. (2003)
{'key': 'ja052279vb00007/ja052279vb00007_1', 'first-page': '11171', 'volume': '125', 'author': 'Zheng B.', 'year': '2003', 'journal-title': 'J. Am. Chem. Soc.'} / J. Am. Chem. Soc. by Zheng B. (2003)
{'key': 'ja052279vb00008/ja052279vb00008_1', 'first-page': '4666', 'volume': '83', 'author': 'Song H.', 'year': '2003', 'journal-title': 'Appl. Phys. Lett.'} / Appl. Phys. Lett. by Song H. (2003)
10.1126/science.1066238 / Science by Stroock A. D. (2002)
10.1039/b403378g / Lab Chip by Shestopalov I. (2004)
{'key': 'ja052279vb00011/ja052279vb00011_1', 'first-page': '31', 'volume': '142', 'author': 'Garcia-Ruiz J. M.', 'year': '2003', 'journal-title': 'J. Struct. Biol.'} / J. Struct. Biol. by Garcia-Ruiz J. M. (2003)
{'key': 'ja052279vb00013/ja052279vb00013_1', 'first-page': '16536', 'volume': '99', 'author': 'Hansen C. L.', 'year': '2002', 'journal-title': 'Proc. Natl. Acad. Sci. U.S.A.'} / Proc. Natl. Acad. Sci. U.S.A. by Hansen C. L. (2002)
{'key': 'ja052279vb00014/ja052279vb00014_1', 'first-page': '9133', 'volume': '19', 'author': 'Tice J. D.', 'year': '2003', 'journal-title': 'Langmuir'} / Langmuir by Tice J. D. (2003)
10.1021/ja031689l / J. Am. Chem. Soc. by Gerdts C. J. (2004)

Dates

Type	When
Created	20 years, 1 month ago (July 6, 2005, 8:23 a.m.)
Deposited	2 years, 5 months ago (March 30, 2023, 2:05 p.m.)
Indexed	1 month, 1 week ago (July 25, 2025, 6:09 a.m.)
Issued	20 years, 2 months ago (June 15, 2005)
Published	20 years, 2 months ago (June 15, 2005)
Published Online	20 years, 2 months ago (June 15, 2005)
Published Print	20 years, 1 month ago (July 13, 2005)

Funders 0

None

BibTeX

@article{Chen_2005, title={Using Microfluidics to Observe the Effect of Mixing on Nucleation of Protein Crystals}, volume={127}, ISSN={1520-5126}, url={http://dx.doi.org/10.1021/ja052279v}, DOI={10.1021/ja052279v}, number={27}, journal={Journal of the American Chemical Society}, publisher={American Chemical Society (ACS)}, author={Chen, Delai L. and Gerdts, Cory J. and Ismagilov, Rustem F.}, year={2005}, month=jun, pages={9672–9673} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        7,
        25
      ]
    ],
    "date-time": "2025-07-25T10:09:31Z",
    "timestamp": 1753438171413
  },
  "reference-count": 14,
  "publisher": "American Chemical Society (ACS)",
  "issue": "27",
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2005,
        7,
        13
      ]
    ]
  },
  "DOI": "10.1021/ja052279v",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2005,
        7,
        6
      ]
    ],
    "date-time": "2005-07-06T12:23:57Z",
    "timestamp": 1120652637000
  },
  "page": "9672-9673",
  "source": "Crossref",
  "is-referenced-by-count": 132,
  "title": "Using Microfluidics to Observe the Effect of Mixing on Nucleation of Protein Crystals",
  "prefix": "10.1021",
  "volume": "127",
  "author": [
    {
      "given": "Delai L.",
      "family": "Chen",
      "sequence": "first",
      "affiliation": [
        {
          "name": "Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637"
        }
      ]
    },
    {
      "given": "Cory J.",
      "family": "Gerdts",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637"
        }
      ]
    },
    {
      "given": "Rustem F.",
      "family": "Ismagilov",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637"
        }
      ]
    }
  ],
  "member": "316",
  "published-online": {
    "date-parts": [
      [
        2005,
        6,
        15
      ]
    ]
  },
  "reference": [
    {
      "key": "ja052279vb00001/ja052279vb00001_1",
      "volume-title": "Crystallization of biological macromolecules",
      "author": "McPherson A.",
      "year": "1999"
    },
    {
      "key": "ja052279vb00002/ja052279vb00002_1",
      "doi-asserted-by": "crossref",
      "first-page": "6281",
      "DOI": "10.1073/pnas.110000497",
      "volume": "97",
      "author": "Galkin O.",
      "year": "2000",
      "journal-title": "Proc. Natl. Acad. Sci. U.S.A."
    },
    {
      "key": "ja052279vb00003/ja052279vb00003_1",
      "doi-asserted-by": "crossref",
      "first-page": "3",
      "DOI": "10.1016/S1047-8477(03)00034-0",
      "volume": "142",
      "author": "Chernov A. A.",
      "year": "2003",
      "journal-title": "J. Struct. Biol."
    },
    {
      "key": "ja052279vb00004/ja052279vb00004_1",
      "first-page": "528",
      "volume": "27",
      "author": "Chen P. C.",
      "year": "2004",
      "journal-title": "Chem. Eng. Technol."
    },
    {
      "key": "ja052279vb00005/ja052279vb00005_1",
      "first-page": "355",
      "volume": "354",
      "author": "Suga S.",
      "year": "2003",
      "journal-title": "Chem. Commun."
    },
    {
      "key": "ja052279vb00006/ja052279vb00006_1",
      "doi-asserted-by": "crossref",
      "first-page": "772",
      "DOI": "10.1002/anie.200390204",
      "volume": "42",
      "author": "Song H.",
      "year": "2003",
      "journal-title": "Angew. Chem., Int. Ed."
    },
    {
      "key": "ja052279vb00007/ja052279vb00007_1",
      "first-page": "11171",
      "volume": "125",
      "author": "Zheng B.",
      "year": "2003",
      "journal-title": "J. Am. Chem. Soc."
    },
    {
      "key": "ja052279vb00008/ja052279vb00008_1",
      "first-page": "4666",
      "volume": "83",
      "author": "Song H.",
      "year": "2003",
      "journal-title": "Appl. Phys. Lett."
    },
    {
      "key": "ja052279vb00009/ja052279vb00009_1",
      "doi-asserted-by": "crossref",
      "first-page": "651",
      "DOI": "10.1126/science.1066238",
      "volume": "295",
      "author": "Stroock A. D.",
      "year": "2002",
      "journal-title": "Science"
    },
    {
      "key": "ja052279vb00010/ja052279vb00010_1",
      "doi-asserted-by": "crossref",
      "first-page": "321",
      "DOI": "10.1039/b403378g",
      "volume": "4",
      "author": "Shestopalov I.",
      "year": "2004",
      "journal-title": "Lab Chip"
    },
    {
      "key": "ja052279vb00011/ja052279vb00011_1",
      "first-page": "31",
      "volume": "142",
      "author": "Garcia-Ruiz J. M.",
      "year": "2003",
      "journal-title": "J. Struct. Biol."
    },
    {
      "key": "ja052279vb00013/ja052279vb00013_1",
      "first-page": "16536",
      "volume": "99",
      "author": "Hansen C. L.",
      "year": "2002",
      "journal-title": "Proc. Natl. Acad. Sci. U.S.A."
    },
    {
      "key": "ja052279vb00014/ja052279vb00014_1",
      "first-page": "9133",
      "volume": "19",
      "author": "Tice J. D.",
      "year": "2003",
      "journal-title": "Langmuir"
    },
    {
      "key": "ja052279vb00015/ja052279vb00015_1",
      "doi-asserted-by": "crossref",
      "first-page": "6331",
      "DOI": "10.1021/ja031689l",
      "volume": "126",
      "author": "Gerdts C. J.",
      "year": "2004",
      "journal-title": "J. Am. Chem. Soc."
    }
  ],
  "container-title": "Journal of the American Chemical Society",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://pubs.acs.org/doi/pdf/10.1021/ja052279v",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        3,
        30
      ]
    ],
    "date-time": "2023-03-30T18:05:32Z",
    "timestamp": 1680199532000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://pubs.acs.org/doi/10.1021/ja052279v"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2005,
        6,
        15
      ]
    ]
  },
  "references-count": 14,
  "journal-issue": {
    "issue": "27",
    "published-print": {
      "date-parts": [
        [
          2005,
          7,
          13
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1021/ja052279v"
  ],
  "URL": "http://dx.doi.org/10.1021/ja052279v",
  "relation": {},
  "ISSN": [
    "0002-7863",
    "1520-5126"
  ],
  "subject": [],
  "container-title-short": "J. Am. Chem. Soc.",
  "published": {
    "date-parts": [
      [
        2005,
        6,
        15
      ]
    ]
  }
}