DOI: 10.1021/bp00020a008. Transient Stirred‐Tank Reactors Operating with Immobilized Enzyme Systems: Analysis and Simulation Models and Their Experimental Checking

Transient Stirred‐Tank Reactors Operating with Immobilized Enzyme Systems: Analysis and Simulation Models and Their Experimental Checking

10.1021/bp00020a008

Crossref journal-article

Wiley

Biotechnology Progress (311)

Abstract

AbstractA mathematical model applicable to the analysis, design, and simulation of heterogeneous enzymatic processes reacting in a stirred‐tank reactor has been formulated. The model develops the unsteady‐state design equations for such reactors and also the diffusion reaction equation in the spherical catalyst particles for reversible Michaelis—Menten kinetics. This structured general model provides an overview of almost all of the processes occurring in an immobilized enzyme reactor system. Although the analysis presented here is limited to certain situations, it can be extended to other support geometries, enzyme kinetics, and reactor configurations. To check the model, the experimental data obtained with immobilized β‐galactosidase were compared to those theoretically predicted.

Bibliography

Santoyo, A. B., Carrasco, J. L. G., GÃ³mez, E. G., Rodriguez, J. B., & Morales, E. M. (1993). Transient StirredâTank Reactors Operating with Immobilized Enzyme Systems: Analysis and Simulation Models and Their Experimental Checking. Biotechnology Progress, 9(2), 166â173. Portico.

Authors 5

A. Bódalo Santoyo (first)
J. L. Gómez Carrasco (additional)
E. Gómez Gómez (additional)
J. Bastida Rodriguez (additional)
E. Martinez Morales (additional)

References 19 Referenced 16

{'key': 'e_1_2_1_2_1', 'first-page': '248', 'article-title': 'The Overall Rate of Substrate Uptake by Microbial Films. A Biological Rate Equation', 'volume': '52', 'author': 'Atkinson B.', 'year': '1974', 'journal-title': 'Trans. Inst. Chem. Eng.'} / Trans. Inst. Chem. Eng. / The Overall Rate of Substrate Uptake by Microbial Films. A Biological Rate Equation by Atkinson B. (1974)
10.1002/bit.260210209
10.1016/0141-0229(86)90153-5
10.1016/0032-9592(91)85025-J
{'key': 'e_1_2_1_6_1', 'first-page': '54', 'volume-title': 'Handbook of Enzyme Technology', 'author': 'Cheetham P. S. J.', 'year': '1985'} / Handbook of Enzyme Technology by Cheetham P. S. J. (1985)
10.1002/bit.260240707
10.1016/0022-5193(73)90153-7
10.1002/bit.260160303
10.1111/j.1745-4530.1977.tb00191.x
10.1016/0003-2697(72)90094-2
{'key': 'e_1_2_1_12_1', 'first-page': '99', 'volume-title': 'Chemical Reaction Engineering', 'author': 'Levenspiel O.', 'year': '1972'} / Chemical Reaction Engineering by Levenspiel O. (1972)
Manjón A.;Llorca F. I.;Bonete M. J.;Bastida J.;Iborra J. L.Properties of β‐Galactosidase Covalently Immobilized to Glycophase‐Coated Porous Glass.Process Biochem.1985 February 17–22.
10.1002/bit.260300405
{'key': 'e_1_2_1_15_1', 'first-page': '317', 'article-title': 'Diseño y Simulación de Reactores Tanque Continuo en Estado Estacionario Para Sistemas con Enzimas Inmovilizadas (Design and Simulation of Steady State Continuous Stirred Tank Reactors for Immobilized Enzyme Systems)', 'volume': '416', 'author': 'Martinez P.', 'year': '1988', 'journal-title': 'Afinidad'} / Afinidad / Diseño y Simulación de Reactores Tanque Continuo en Estado Estacionario Para Sistemas con Enzimas Inmovilizadas (Design and Simulation of Steady State Continuous Stirred Tank Reactors for Immobilized Enzyme Systems) by Martinez P. (1988)
10.1016/B978-0-12-492350-8.50009-8
10.1093/comjnl/7.4.308
10.1016/0009-2509(75)85091-3
{'key': 'e_1_2_1_19_1', 'first-page': '85', 'article-title': 'Optimization Via the Simplex Method', 'volume': '15', 'author': 'Tao B. Y.', 'year': '1988', 'journal-title': 'Chem. Eng.'} / Chem. Eng. / Optimization Via the Simplex Method by Tao B. Y. (1988)
{'key': 'e_1_2_1_20_1', 'first-page': '222', 'volume-title': 'Applied Biochemistry and Bioengineering. Volume 1: Immobilized Enzyme Principles', 'author': 'Vieth W. R.', 'year': '1976'} / Applied Biochemistry and Bioengineering. Volume 1: Immobilized Enzyme Principles by Vieth W. R. (1976)

Dates

Type	When
Created	20 years, 5 months ago (March 16, 2005, 3:18 p.m.)
Deposited	1 year, 10 months ago (Oct. 24, 2023, 3:15 p.m.)
Indexed	11 months, 3 weeks ago (Sept. 6, 2024, 3:06 a.m.)
Issued	32 years, 6 months ago (March 1, 1993)
Published	32 years, 6 months ago (March 1, 1993)
Published Online	16 years, 11 months ago (Sept. 5, 2008)
Published Print	32 years, 6 months ago (March 1, 1993)

Funders 0

None

BibTeX

@article{Santoyo_1993, title={Transient Stirred‐Tank Reactors Operating with Immobilized Enzyme Systems: Analysis and Simulation Models and Their Experimental Checking}, volume={9}, ISSN={1520-6033}, url={http://dx.doi.org/10.1021/bp00020a008}, DOI={10.1021/bp00020a008}, number={2}, journal={Biotechnology Progress}, publisher={Wiley}, author={Santoyo, A. Bódalo and Carrasco, J. L. Gómez and Gómez, E. Gómez and Rodriguez, J. Bastida and Morales, E. Martinez}, year={1993}, month=mar, pages={166–173} }

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