DOI: 10.1021/bi992399d. HIV-1 Protease Inhibitors: Enthalpic versus Entropic Optimization of the Binding Affinity

HIV-1 Protease Inhibitors: Enthalpic versus Entropic Optimization of the Binding Affinity

10.1021/bi992399d

Crossref journal-article

American Chemical Society (ACS)

Biochemistry (316)

Bibliography

Velazquez-Campoy, A., Todd, M. J., & Freire, E. (2000). HIV-1 Protease Inhibitors:â Enthalpic versus Entropic Optimization of the Binding Affinity. Biochemistry, 39(9), 2201â2207.

Authors 3

Adrian Velazquez-Campoy (first)
Matthew J. Todd (additional)
Ernesto Freire (additional)

References 17 Referenced 119

{'key': 'bi992399db00001/bi992399db00001_1', 'volume-title': 'Biochemistry 36, 6588−6596', 'author': 'Bardi J. S.', 'year': '1997'} / Biochemistry 36, 6588−6596 by Bardi J. S. (1997)
{'key': 'bi992399db00002/bi992399db00002_1', 'volume-title': 'Biochemistry 37, 5791−5797', 'author': 'Luque I.', 'year': '1998'} / Biochemistry 37, 5791−5797 by Luque I. (1998)
{'key': 'bi992399db00003/bi992399db00003_1', 'volume-title': 'Proteins 36, 147−156', 'author': 'Todd M. J.', 'year': '1999'} / Proteins 36, 147−156 by Todd M. J. (1999)
{'key': 'bi992399db00004/bi992399db00004_1', 'volume': '283', 'author': 'Todd M. J.', 'year': '1998', 'journal-title': 'J. Mol. Biol.'} / J. Mol. Biol. by Todd M. J. (1998)
{'key': 'bi992399db00005/bi992399db00005_1', 'volume-title': 'Biochemistry 37, 2105−2110', 'author': 'Louis J. M.', 'year': '1998'} / Biochemistry 37, 2105−2110 by Louis J. M. (1998)
{'key': 'bi992399db00006/bi992399db00006_1', 'volume-title': 'Biochemistry 35, 10279−10286', 'author': 'Hoog S. S.', 'year': '1996'} / Biochemistry 35, 10279−10286 by Hoog S. S. (1996)
{'key': 'bi992399db00007/bi992399db00007_1', 'volume-title': 'Adv. Protein Chem. 43, 313−361', 'author': 'Murphy K. P.', 'year': '1992'} / Adv. Protein Chem. 43, 313−361 by Murphy K. P. (1992)
{'key': 'bi992399db00008/bi992399db00008_1', 'volume-title': 'Funct., Genet. 15, 113−120.', 'author': 'Murphy K. P.', 'year': '1993'} / Funct., Genet. 15, 113−120. by Murphy K. P. (1993)
10.1006/jmbi.1995.0501 / J. Mol. Biol. by Gomez J. (1995)
{'key': 'bi992399db00010/bi992399db00010_1', 'volume-title': 'Funct., Genet. 22, 404−412.', 'author': 'Gomez J.', 'year': '1995'} / Funct., Genet. 22, 404−412. by Gomez J. (1995)
{'key': 'bi992399db00011/bi992399db00011_1', 'first-page': '84', 'volume': '20', 'author': 'Lee K. H.', 'year': '1994', 'journal-title': 'Genet.'} / Genet. by Lee K. H. (1994)
{'key': 'bi992399db00012/bi992399db00012_1', 'volume-title': 'Proteins 26, 123−133', 'author': 'Hilser V. J.', 'year': '1996'} / Proteins 26, 123−133 by Hilser V. J. (1996)
{'key': 'bi992399db00013/bi992399db00013_1', 'volume-title': 'Proteins 25, 143−156', 'author': 'Aquino J. A.', 'year': '1996'} / Proteins 25, 143−156 by Aquino J. A. (1996)
{'key': 'bi992399db00014/bi992399db00014_1', 'volume-title': 'Biochemistry 35, 13681−13688', 'author': 'Luque I.', 'year': '1996'} / Biochemistry 35, 13681−13688 by Luque I. (1996)
{'key': 'bi992399db00015/bi992399db00015_1', 'volume-title': 'Methods Enzymol. 295, 100−127', 'author': 'Luque I.', 'year': '1998'} / Methods Enzymol. 295, 100−127 by Luque I. (1998)
10.1006/jmbi.1998.2171 / J. Mol. Biol. by Hsiou Y. (1998)
{'key': 'bi992399dn00001/bi992399dn00001_1', 'volume-title': 'statine', 'author': 'Abbreviations'} / statine by Abbreviations

Dates

Type	When
Created	23 years ago (July 26, 2002, 1:51 a.m.)
Deposited	3 years, 10 months ago (Sept. 23, 2021, 11:19 p.m.)
Indexed	3 months, 2 weeks ago (May 7, 2025, 7:31 a.m.)
Issued	25 years, 6 months ago (Feb. 12, 2000)
Published	25 years, 6 months ago (Feb. 12, 2000)
Published Online	25 years, 6 months ago (Feb. 12, 2000)
Published Print	25 years, 5 months ago (March 1, 2000)

Funders 0

None

BibTeX

@article{Velazquez_Campoy_2000, title={HIV-1 Protease Inhibitors: Enthalpic versus Entropic Optimization of the Binding Affinity}, volume={39}, ISSN={1520-4995}, url={http://dx.doi.org/10.1021/bi992399d}, DOI={10.1021/bi992399d}, number={9}, journal={Biochemistry}, publisher={American Chemical Society (ACS)}, author={Velazquez-Campoy, Adrian and Todd, Matthew J. and Freire, Ernesto}, year={2000}, month=feb, pages={2201–2207} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        5,
        7
      ]
    ],
    "date-time": "2025-05-07T11:31:53Z",
    "timestamp": 1746617513345
  },
  "reference-count": 17,
  "publisher": "American Chemical Society (ACS)",
  "issue": "9",
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2000,
        3,
        1
      ]
    ]
  },
  "DOI": "10.1021/bi992399d",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        26
      ]
    ],
    "date-time": "2002-07-26T05:51:53Z",
    "timestamp": 1027662713000
  },
  "page": "2201-2207",
  "source": "Crossref",
  "is-referenced-by-count": 119,
  "title": "HIV-1 Protease Inhibitors:\u2009 Enthalpic versus Entropic Optimization of the Binding Affinity",
  "prefix": "10.1021",
  "volume": "39",
  "author": [
    {
      "given": "Adrian",
      "family": "Velazquez-Campoy",
      "sequence": "first",
      "affiliation": [
        {
          "name": "Department of Biology and Biocalorimetry Center, The Johns Hopkins University, Baltimore, Maryland 21218"
        }
      ]
    },
    {
      "given": "Matthew J.",
      "family": "Todd",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Biology and Biocalorimetry Center, The Johns Hopkins University, Baltimore, Maryland 21218"
        }
      ]
    },
    {
      "given": "Ernesto",
      "family": "Freire",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Biology and Biocalorimetry Center, The Johns Hopkins University, Baltimore, Maryland 21218"
        }
      ]
    }
  ],
  "member": "316",
  "published-online": {
    "date-parts": [
      [
        2000,
        2,
        12
      ]
    ]
  },
  "reference": [
    {
      "key": "bi992399db00001/bi992399db00001_1",
      "volume-title": "Biochemistry 36, 6588\u22126596",
      "author": "Bardi J. S.",
      "year": "1997"
    },
    {
      "key": "bi992399db00002/bi992399db00002_1",
      "volume-title": "Biochemistry 37, 5791\u22125797",
      "author": "Luque I.",
      "year": "1998"
    },
    {
      "key": "bi992399db00003/bi992399db00003_1",
      "volume-title": "Proteins 36, 147\u2212156",
      "author": "Todd M. J.",
      "year": "1999"
    },
    {
      "key": "bi992399db00004/bi992399db00004_1",
      "volume": "283",
      "author": "Todd M. J.",
      "year": "1998",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "bi992399db00005/bi992399db00005_1",
      "volume-title": "Biochemistry 37, 2105\u22122110",
      "author": "Louis J. M.",
      "year": "1998"
    },
    {
      "key": "bi992399db00006/bi992399db00006_1",
      "volume-title": "Biochemistry 35, 10279\u221210286",
      "author": "Hoog S. S.",
      "year": "1996"
    },
    {
      "key": "bi992399db00007/bi992399db00007_1",
      "volume-title": "Adv. Protein Chem. 43, 313\u2212361",
      "author": "Murphy K. P.",
      "year": "1992"
    },
    {
      "key": "bi992399db00008/bi992399db00008_1",
      "volume-title": "Funct., Genet. 15, 113\u2212120.",
      "author": "Murphy K. P.",
      "year": "1993"
    },
    {
      "key": "bi992399db00009/bi992399db00009_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1006/jmbi.1995.0501",
      "volume": "252",
      "author": "Gomez J.",
      "year": "1995",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "bi992399db00010/bi992399db00010_1",
      "volume-title": "Funct., Genet. 22, 404\u2212412.",
      "author": "Gomez J.",
      "year": "1995"
    },
    {
      "key": "bi992399db00011/bi992399db00011_1",
      "first-page": "84",
      "volume": "20",
      "author": "Lee K. H.",
      "year": "1994",
      "journal-title": "Genet."
    },
    {
      "key": "bi992399db00012/bi992399db00012_1",
      "volume-title": "Proteins 26, 123\u2212133",
      "author": "Hilser V. J.",
      "year": "1996"
    },
    {
      "key": "bi992399db00013/bi992399db00013_1",
      "volume-title": "Proteins 25, 143\u2212156",
      "author": "Aquino J. A.",
      "year": "1996"
    },
    {
      "key": "bi992399db00014/bi992399db00014_1",
      "volume-title": "Biochemistry 35, 13681\u221213688",
      "author": "Luque I.",
      "year": "1996"
    },
    {
      "key": "bi992399db00015/bi992399db00015_1",
      "volume-title": "Methods Enzymol. 295, 100\u2212127",
      "author": "Luque I.",
      "year": "1998"
    },
    {
      "key": "bi992399db00016/bi992399db00016_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1006/jmbi.1998.2171",
      "volume": "284",
      "author": "Hsiou Y.",
      "year": "1998",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "bi992399dn00001/bi992399dn00001_1",
      "volume-title": "statine",
      "author": "Abbreviations"
    }
  ],
  "container-title": "Biochemistry",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://pubs.acs.org/doi/pdf/10.1021/bi992399d",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2021,
        9,
        24
      ]
    ],
    "date-time": "2021-09-24T03:19:16Z",
    "timestamp": 1632453556000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://pubs.acs.org/doi/10.1021/bi992399d"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2000,
        2,
        12
      ]
    ]
  },
  "references-count": 17,
  "journal-issue": {
    "issue": "9",
    "published-print": {
      "date-parts": [
        [
          2000,
          3,
          1
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1021/bi992399d"
  ],
  "URL": "http://dx.doi.org/10.1021/bi992399d",
  "relation": {},
  "ISSN": [
    "0006-2960",
    "1520-4995"
  ],
  "subject": [],
  "container-title-short": "Biochemistry",
  "published": {
    "date-parts": [
      [
        2000,
        2,
        12
      ]
    ]
  }
}