DOI: 10.1021/bi960831a. Secondary H/T and D/T Isotope Effects in Enzymatic Enolization Reactions. Coupled Motion and Tunneling in the Triosephosphate Isomerase Reaction

Secondary H/T and D/T Isotope Effects in Enzymatic Enolization Reactions. Coupled Motion and Tunneling in the Triosephosphate Isomerase Reaction

10.1021/bi960831a

Crossref journal-article

American Chemical Society (ACS)

Biochemistry (316)

Bibliography

Alston, W. C., Kanska, M., & Murray, C. J. (1996). Secondary H/T and D/T Isotope Effects in Enzymatic Enolization Reactions. Coupled Motion and Tunneling in the Triosephosphate Isomerase Reaction. Biochemistry, 35(39), 12873â12881.

Authors 3

William C. Alston (first)
Marianna Kanska (additional)
Christopher J. Murray (additional)

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In principle, there may be a small contribution to the secondary isotope effect from the enediol(ate) to GAP isomerization step,k3. However, this isotope effect is expected to be small and slightly inverse (Cleland, 1987), as the C-1 carbon remains sp2hybridized in both species.
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Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 1:21 a.m.)
Deposited	3 years, 11 months ago (Sept. 22, 2021, 6:37 a.m.)
Indexed	3 months ago (June 6, 2025, 2:04 a.m.)
Issued	29 years, 8 months ago (Jan. 1, 1996)
Published	29 years, 8 months ago (Jan. 1, 1996)
Published Online	28 years, 11 months ago (Oct. 1, 1996)
Published Print	29 years, 8 months ago (Jan. 1, 1996)

Funders 0

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BibTeX

@article{Alston_1996, title={Secondary H/T and D/T Isotope Effects in Enzymatic Enolization Reactions. Coupled Motion and Tunneling in the Triosephosphate Isomerase Reaction}, volume={35}, ISSN={1520-4995}, url={http://dx.doi.org/10.1021/bi960831a}, DOI={10.1021/bi960831a}, number={39}, journal={Biochemistry}, publisher={American Chemical Society (ACS)}, author={Alston, William C. and Kanska, Marianna and Murray, Christopher J.}, year={1996}, month=jan, pages={12873–12881} }

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