DOI: 10.1021/bi025563x. Proton Transfers in the Photochemical Reaction Cycle of Proteorhodopsin

Proton Transfers in the Photochemical Reaction Cycle of Proteorhodopsin

10.1021/bi025563x

Crossref journal-article

American Chemical Society (ACS)

Biochemistry (316)

Bibliography

Dioumaev, A. K., Brown, L. S., Shih, J., Spudich, E. N., Spudich, J. L., & Lanyi, J. K. (2002). Proton Transfers in the Photochemical Reaction Cycle of Proteorhodopsin. Biochemistry, 41(17), 5348â5358.

Authors 6

Andrei K. Dioumaev (first)
Leonid S. Brown (additional)
Jennifer Shih (additional)
Elena N. Spudich (additional)
John L. Spudich (additional)
Janos K. Lanyi (additional)

References 58 Referenced 198

10.1146/annurev.cellbio.16.1.365 / Annu. Rev. Cell Dev. Biol. by Spudich J. L. (2000)
{'key': 'bi025563xb00002/bi025563xb00002_1', 'volume-title': 'NOP-1, binds retinal to form an archaeal rhodopsin-like photochemically reactive pigment. Biochemistry 38, 14138−14145.', 'author': 'Bieszke J. A.', 'year': '1999'} / NOP-1, binds retinal to form an archaeal rhodopsin-like photochemically reactive pigment. Biochemistry 38, 14138−14145. by Bieszke J. A. (1999)
{'key': 'bi025563xb00003/bi025563xb00003_1', 'volume-title': 'Characterization of an opsin gene from the ascomycete Leptosphaeria maculans. Genome 44, 167−171', 'author': 'Idnurm A.', 'year': '2001'} / Characterization of an opsin gene from the ascomycete Leptosphaeria maculans. Genome 44, 167−171 by Idnurm A. (2001)
{'key': 'bi025563xb00004/bi025563xb00004_1', 'volume': '276', 'author': 'Brown L. S.', 'year': '2001', 'journal-title': 'J. Biol. Chem.'} / J. Biol. Chem. by Brown L. S. (2001)
{'key': 'bi025563xb00005/bi025563xb00005_1', 'volume-title': 'Bacterial rhodopsin:\u2009 evidence for a new type of phototrophy in the sea. Science 289', 'author': 'Béjà O.', 'year': '2000'} / Bacterial rhodopsin: evidence for a new type of phototrophy in the sea. Science 289 by Béjà O. (2000)
{'key': 'bi025563xb00006/bi025563xb00006_1', 'volume-title': 'Proteorhodopsin phototrophy in the ocean. Nature 411, 786−789', 'author': 'Béjà O.', 'year': '2001'} / Proteorhodopsin phototrophy in the ocean. Nature 411, 786−789 by Béjà O. (2001)
{'key': 'bi025563xb00007/bi025563xb00007_1', 'volume': '270', 'author': 'Brown L. S.', 'year': '1995', 'journal-title': 'J. Biol. Chem.'} / J. Biol. Chem. by Brown L. S. (1995)
{'key': 'bi025563xb00008/bi025563xb00008_1', 'volume-title': 'Glutamate-194 to cysteine mutation inhibits fast light-induced proton release in bacteriorhodopsin. Biochemistry 36, 8671−8676', 'author': 'Balashov S. P.', 'year': '1997'} / Glutamate-194 to cysteine mutation inhibits fast light-induced proton release in bacteriorhodopsin. Biochemistry 36, 8671−8676 by Balashov S. P. (1997)
{'key': 'bi025563xb00009/bi025563xb00009_1', 'volume-title': 'An efficient site-directed mutagenesis method based on PCR. Biotechniques 17, 657−659', 'author': 'Chen B.', 'year': '1994'} / An efficient site-directed mutagenesis method based on PCR. Biotechniques 17, 657−659 by Chen B. (1994)
{'key': 'bi025563xb00010/bi025563xb00010_1', 'volume': '134', 'author': 'Elish M. E.', 'year': '1988', 'journal-title': 'J. Gen. Microbiol.'} / J. Gen. Microbiol. by Elish M. E. (1988)
{'key': 'bi025563xb00011/bi025563xb00011_1', 'volume-title': 'Fourier transform infrared spectra of a late intermediate of the bacteriorhodopsin photocycle suggest transient protonation of Asp-212. Biochemistry 38, 10070−10078', 'author': 'Dioumaev A. K.', 'year': '1999'} / Fourier transform infrared spectra of a late intermediate of the bacteriorhodopsin photocycle suggest transient protonation of Asp-212. Biochemistry 38, 10070−10078 by Dioumaev A. K. (1999)
{'key': 'bi025563xb00012/bi025563xb00012_1', 'volume-title': 'Coupling of the reisomerization of the retinal, proton uptake, and reprotonation of Asp-96 in the N photointermediate of bacteriorhodopsin. Biochemistry 40, 11308−11317', 'author': 'Dioumaev A. K.', 'year': '2001'} / Coupling of the reisomerization of the retinal, proton uptake, and reprotonation of Asp-96 in the N photointermediate of bacteriorhodopsin. Biochemistry 40, 11308−11317 by Dioumaev A. K. (2001)
10.1016/S0301-4622(96)02268-5 / Biophys. Chem. by Dioumaev A. K. (1997)
{'key': 'bi025563xb00014/bi025563xb00014_1', 'volume-title': 'Existence of a proton-transfer chain in bacteriorhodopsin:\u2009 participation of Glu-194 in the release of protons to the extracellular surface. Biochemistry 37, 2496−2506', 'author': 'Dioumaev A. K.', 'year': '1998'} / Existence of a proton-transfer chain in bacteriorhodopsin: participation of Glu-194 in the release of protons to the extracellular surface. Biochemistry 37, 2496−2506 by Dioumaev A. K. (1998)
{'key': 'bi025563xb00015/bi025563xb00015_1', 'volume-title': 'Titration of individual components in a mixture with resolution of difference spectra, pKs, and redox transitions. Anal. Chem. 54, 1147−1152', 'author': 'Shrager R. I.', 'year': '1982'} / Titration of individual components in a mixture with resolution of difference spectra, pKs, and redox transitions. Anal. Chem. 54, 1147−1152 by Shrager R. I. (1982)
10.1016/S0006-3495(98)74064-0 / Biophys. J. by Brown L. S. (1998)
10.1016/0014-5793(86)81045-6 / FEBS Lett. by Grzesiek S. (1986)
{'key': 'bi025563xb00018/bi025563xb00018_1', 'volume-title': 'Vibrational spectroscopy of bacteriorhodopsin mutants:\u2009 light-driven proton transport 5357 involves protonation changes of aspartic acid residues 85, 96, and 212. Biochemistry 27, 8516−8520', 'author': 'Braiman M. S.', 'year': '1988'} / Vibrational spectroscopy of bacteriorhodopsin mutants: light-driven proton transport 5357 involves protonation changes of aspartic acid residues 85, 96, and 212. Biochemistry 27, 8516−8520 by Braiman M. S. (1988)
{'key': 'bi025563xb00019/bi025563xb00019_1', 'volume-title': 'Proc. Natl. Acad. Sci. U.S.A. 88', 'author': 'Braiman M. S.', 'year': '1991'} / Proc. Natl. Acad. Sci. U.S.A. 88 by Braiman M. S. (1991)
Fahmy, K., Weidlich, O., Engelhard, M., Tittor, J., Oesterhelt, D., and Siebert, F. (1992) Identification of the proton acceptor of Schiff base deprotonation in bacteriorhodopsin: a Fourier transform infrared study of the mutant Asp85 → Glu in its natural lipid environment.Photochem. Photobiol.56, 1073−1083. (10.1111/j.1751-1097.1992.tb09731.x)
{'key': 'bi025563xb00021/bi025563xb00021_1', 'volume-title': 'Proc. Natl. Acad. Sci. U.S.A. 87', 'author': 'Subramaniam S.', 'year': '1990'} / Proc. Natl. Acad. Sci. U.S.A. 87 by Subramaniam S. (1990)
{'key': 'bi025563xb00022/bi025563xb00022_1', 'volume-title': 'Proc. Natl. Acad. Sci. U.S.A. 87', 'author': 'Otto H.', 'year': '1990'} / Proc. Natl. Acad. Sci. U.S.A. 87 by Otto H. (1990)
{'key': 'bi025563xb00023/bi025563xb00023_1', 'volume-title': 'Rhodopsin-like protein from the purple membrane of Halobacterium halobium. Nat. New Biol. 233, 149−152', 'author': 'Oesterhelt D.', 'year': '1971'} / Rhodopsin-like protein from the purple membrane of Halobacterium halobium. Nat. New Biol. 233, 149−152 by Oesterhelt D. (1971)
10.1016/0005-2728(92)90193-6 / Biochim. Biophys. Acta by Lanyi J. K. (1992)
{'key': 'bi025563xb00025/bi025563xb00025_1', 'volume': '71', 'author': 'Richter H.-T.', 'year': '1996', 'journal-title': 'Biophys. J.'} / Biophys. J. by Richter H.-T. (1996)
10.1016/S0006-3495(96)79591-7 / Biophys. J. by Balashov S. P. (1996)
{'key': 'bi025563xb00027/bi025563xb00027_1', 'volume': '8', 'author': 'Butt H.-J.', 'year': '1989', 'journal-title': 'EMBO J.'} / EMBO J. by Butt H.-J. (1989)
{'key': 'bi025563xb00028/bi025563xb00028_1', 'volume-title': 'Proc. Natl. Acad. Sci. U.S.A. 87', 'author': 'Sawatzki J.', 'year': '1990'} / Proc. Natl. Acad. Sci. U.S.A. 87 by Sawatzki J. (1990)
10.1021/j100242a011 / J. Phys. Chem. by Kakitani H. (1983)
{'key': 'bi025563xb00030/bi025563xb00030_1', 'volume': '91', 'author': 'Smith S. O.', 'year': '1987', 'journal-title': 'J. Phys. Chem.'} / J. Phys. Chem. by Smith S. O. (1987)
{'key': 'bi025563xb00031/bi025563xb00031_1', 'volume': '109', 'author': 'Smith S. O.', 'year': '1987', 'journal-title': 'J. Am. Chem. Soc.'} / J. Am. Chem. Soc. by Smith S. O. (1987)
{'key': 'bi025563xb00032/bi025563xb00032_1', 'volume-title': "Chromophore structure in bacteriorhodopsin's O640 photointermediate. Biochemistry 22, 6141−6148", 'author': 'Smith S. O.', 'year': '1983'} / Chromophore structure in bacteriorhodopsin's O640 photointermediate. Biochemistry 22, 6141−6148 by Smith S. O. (1983)
{'key': 'bi025563xb00033/bi025563xb00033_1', 'volume-title': 'Time-resolved Fourier transform infrared study of structural changes in the last steps of the photocycles of Glu-204 and Leu-93 mutants of bacteriorhodopsin. Biochemistry 36, 5134−5141', 'author': 'Kandori H.', 'year': '1997'} / Time-resolved Fourier transform infrared study of structural changes in the last steps of the photocycles of Glu-204 and Leu-93 mutants of bacteriorhodopsin. Biochemistry 36, 5134−5141 by Kandori H. (1997)
10.1021/jp971047i / J. Phys. Chem. B. by Zscherp C. (1997)
10.1016/S0006-3495(89)82761-4 / Biophys. J. by Váró G. (1989)
{'key': 'bi025563xb00036/bi025563xb00036_1', 'volume-title': 'The retinal Schiff base-counterion complex of bacteriorhodopsin:\u2009 changed geometry during the photocycle is a cause of proton transfer to aspartate 85. Biochemistry 33, 12001−12011', 'author': 'Brown L. S.', 'year': '1994'} / The retinal Schiff base-counterion complex of bacteriorhodopsin: changed geometry during the photocycle is a cause of proton transfer to aspartate 85. Biochemistry 33, 12001−12011 by Brown L. S. (1994)
{'key': 'bi025563xb00037/bi025563xb00037_1', 'volume-title': 'Proc. Natl. Acad. Sci. U.S.A. 86', 'author': 'Holz M.', 'year': '1989'} / Proc. Natl. Acad. Sci. U.S.A. 86 by Holz M. (1989)
{'key': 'bi025563xb00038/bi025563xb00038_1', 'volume-title': 'Proc. Natl. Acad. Sci. U.S.A. 86', 'author': 'Otto H.', 'year': '1989'} / Proc. Natl. Acad. Sci. U.S.A. 86 by Otto H. (1989)
10.1002/j.1460-2075.1989.tb08512.x / EMBO J. by Tittor J. (1989)
{'key': 'bi025563xb00040/bi025563xb00040_1', 'volume-title': 'Water is required for proton transfer from aspartate-96 to the bacteriorhodopsin Schiff base. Biochemistry 30, 10972−10979', 'author': 'Cao Y.', 'year': '1991'} / Water is required for proton transfer from aspartate-96 to the bacteriorhodopsin Schiff base. Biochemistry 30, 10972−10979 by Cao Y. (1991)
10.1016/0014-5793(92)81202-W / FEBS Lett. by Drachev L. A. (1992)
10.1021/jp963243f / J. Phys. Chem. B. by Delaney J. K. (1997)
{'key': 'bi025563xb00043/bi025563xb00043_1', 'volume-title': 'Pathways of proton release in the bacteriorhodopsin photocycle. Biochemistry 31, 8535−8543', 'author': 'Zimányi L.', 'year': '1992'} / Pathways of proton release in the bacteriorhodopsin photocycle. Biochemistry 31, 8535−8543 by Zimányi L. (1992)
Cao, Y., Brown, L. S., Needleman, R., and Lanyi, J. K. (1993) Relationship of proton uptake on the cytoplasmic surface and reisomerization of the retinal in the bacteriorhodopsin photocycle: An attempt to understand the complex kinetics of the pH changes and the N and O intermediates.Biochemistry32, 10239−10248. (10.1021/bi00089a046)
10.1016/S0006-3495(93)81264-5 / Biophys. J. by Hessling B. (1993)
{'key': 'bi025563xb00046/bi025563xb00046_1', 'volume-title': 'FTIR analysis of the SII540 intermediate of sensory rhodopsin II:\u2009 Asp73 is the Schiff base proton acceptor. Biochemistry 39, 2823−2830', 'author': 'Bergo V.', 'year': '2000'} / FTIR analysis of the SII540 intermediate of sensory rhodopsin II: Asp73 is the Schiff base proton acceptor. Biochemistry 39, 2823−2830 by Bergo V. (2000)
{'key': 'bi025563xb00047/bi025563xb00047_1', 'volume-title': 'Conformational changes of bacteriorhodopsin detected by Fourier transform infrared difference spectroscopy. Biochim. Biophys. Res. Commun. 103, 483−489', 'author': 'Rothschild K. J.', 'year': '1981'} / Conformational changes of bacteriorhodopsin detected by Fourier transform infrared difference spectroscopy. Biochim. Biophys. Res. Commun. 103, 483−489 by Rothschild K. J. (1981)
10.1016/0014-5793(82)80021-5 / FEBS Lett. by Siebert F. (1982)
10.1002/ijch.199500038 / Israel J. Chem. by Maeda A. (1995)
10.1002/ijch.199500029 / Israel J. Chem. by Althaus T. (1995)
{'key': 'bi025563xb00051/bi025563xb00051_1', 'volume-title': 'Fourier transform infrared study of the N intermediate of bacteriorhodopsin. Biochemistry 30, 6548−6556', 'author': 'Pfefferlé J.-M.', 'year': '1991'} / Fourier transform infrared study of the N intermediate of bacteriorhodopsin. Biochemistry 30, 6548−6556 by Pfefferlé J.-M. (1991)
10.1016/S0021-9258(18)99128-3 / J. Biol. Chem. by Bousché O. (1991)
{'key': 'bi025563xb00053/bi025563xb00053_1', 'volume-title': 'Infrared methods for monitoring the protonation state of carboxylic amino acids in the photocycle of bacteriorhodopsin. Biochemistry (Moscow) 66, 1269−1276', 'author': 'Dioumaev A. K.', 'year': '2001'} / Infrared methods for monitoring the protonation state of carboxylic amino acids in the photocycle of bacteriorhodopsin. Biochemistry (Moscow) 66, 1269−1276 by Dioumaev A. K. (2001)
10.1016/0016-7037(79)90184-4 / Geochim. Cosmochim. Acta by Millero F. J. (1979)
Weidlich, O., and Siebert, F. (1993) Time-resolved step scan FTIR investigations of the transition from KL to L in the bacteriorhodopsin photocycle. Identification of chromophore twists by assigning hydrogen out of plane (HOOP) bending vibrations.Appl. Spectrosc.47, 1394−1400. (10.1366/0003702934067351)
{'key': 'bi025563xb00056/bi025563xb00056_1', 'volume-title': 'Time-resolved infrared spectral analysis of the KL-to-L conversion in the photocycle of bacteriorhodopsin. Biochemistry 32, 867−871', 'author': 'Sasaki J.', 'year': '1993'} / Time-resolved infrared spectral analysis of the KL-to-L conversion in the photocycle of bacteriorhodopsin. Biochemistry 32, 867−871 by Sasaki J. (1993)
10.1021/jp961512w / J. Phys. Chem. B. by Dioumaev A. K. (1997)
{'key': 'bi025563xn00001/bi025563xn00001_1', 'volume-title': 'BR, bacteriorhodopsin', 'author': 'Abbreviations'} / BR, bacteriorhodopsin by Abbreviations

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 2:10 a.m.)
Deposited	2 years, 5 months ago (March 6, 2023, 3:52 a.m.)
Indexed	1 week, 1 day ago (Aug. 26, 2025, 3:15 a.m.)
Issued	23 years, 5 months ago (April 1, 2002)
Published	23 years, 5 months ago (April 1, 2002)
Published Online	23 years, 4 months ago (April 9, 2002)
Published Print	23 years, 5 months ago (April 1, 2002)

Funders 0

None

BibTeX

@article{Dioumaev_2002, title={Proton Transfers in the Photochemical Reaction Cycle of Proteorhodopsin}, volume={41}, ISSN={1520-4995}, url={http://dx.doi.org/10.1021/bi025563x}, DOI={10.1021/bi025563x}, number={17}, journal={Biochemistry}, publisher={American Chemical Society (ACS)}, author={Dioumaev, Andrei K. and Brown, Leonid S. and Shih, Jennifer and Spudich, Elena N. and Spudich, John L. and Lanyi, Janos K.}, year={2002}, month=apr, pages={5348–5358} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        26
      ]
    ],
    "date-time": "2025-08-26T07:15:14Z",
    "timestamp": 1756192514157
  },
  "reference-count": 58,
  "publisher": "American Chemical Society (ACS)",
  "issue": "17",
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2002,
        4,
        1
      ]
    ]
  },
  "DOI": "10.1021/bi025563x",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        26
      ]
    ],
    "date-time": "2002-07-26T06:10:37Z",
    "timestamp": 1027663837000
  },
  "page": "5348-5358",
  "source": "Crossref",
  "is-referenced-by-count": 198,
  "title": "Proton Transfers in the Photochemical Reaction Cycle of Proteorhodopsin",
  "prefix": "10.1021",
  "volume": "41",
  "author": [
    {
      "given": "Andrei K.",
      "family": "Dioumaev",
      "sequence": "first",
      "affiliation": [
        {
          "name": "Department of Physiology & Biophysics, University of California, Irvine, California 92697 and Department of Microbiology & Molecular Genetics and Structural Biology Center, The University of Texas Medical School, Houston, Texas 77030"
        }
      ]
    },
    {
      "given": "Leonid S.",
      "family": "Brown",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Physiology & Biophysics, University of California, Irvine, California 92697 and Department of Microbiology & Molecular Genetics and Structural Biology Center, The University of Texas Medical School, Houston, Texas 77030"
        }
      ]
    },
    {
      "given": "Jennifer",
      "family": "Shih",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Physiology & Biophysics, University of California, Irvine, California 92697 and Department of Microbiology & Molecular Genetics and Structural Biology Center, The University of Texas Medical School, Houston, Texas 77030"
        }
      ]
    },
    {
      "given": "Elena N.",
      "family": "Spudich",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Physiology & Biophysics, University of California, Irvine, California 92697 and Department of Microbiology & Molecular Genetics and Structural Biology Center, The University of Texas Medical School, Houston, Texas 77030"
        }
      ]
    },
    {
      "given": "John L.",
      "family": "Spudich",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Physiology & Biophysics, University of California, Irvine, California 92697 and Department of Microbiology & Molecular Genetics and Structural Biology Center, The University of Texas Medical School, Houston, Texas 77030"
        }
      ]
    },
    {
      "given": "Janos K.",
      "family": "Lanyi",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Physiology & Biophysics, University of California, Irvine, California 92697 and Department of Microbiology & Molecular Genetics and Structural Biology Center, The University of Texas Medical School, Houston, Texas 77030"
        }
      ]
    }
  ],
  "member": "316",
  "published-online": {
    "date-parts": [
      [
        2002,
        4,
        9
      ]
    ]
  },
  "reference": [
    {
      "key": "bi025563xb00001/bi025563xb00001_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1146/annurev.cellbio.16.1.365",
      "volume": "16",
      "author": "Spudich J. L.",
      "year": "2000",
      "journal-title": "Annu. Rev. Cell Dev. Biol."
    },
    {
      "key": "bi025563xb00002/bi025563xb00002_1",
      "volume-title": "NOP-1, binds retinal to form an archaeal rhodopsin-like photochemically reactive pigment. Biochemistry 38, 14138\u221214145.",
      "author": "Bieszke J. A.",
      "year": "1999"
    },
    {
      "key": "bi025563xb00003/bi025563xb00003_1",
      "volume-title": "Characterization of an opsin gene from the ascomycete Leptosphaeria maculans. Genome 44, 167\u2212171",
      "author": "Idnurm A.",
      "year": "2001"
    },
    {
      "key": "bi025563xb00004/bi025563xb00004_1",
      "volume": "276",
      "author": "Brown L. S.",
      "year": "2001",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "bi025563xb00005/bi025563xb00005_1",
      "volume-title": "Bacterial rhodopsin:\u2009 evidence for a new type of phototrophy in the sea. Science 289",
      "author": "B\u00e9j\u00e0 O.",
      "year": "2000"
    },
    {
      "key": "bi025563xb00006/bi025563xb00006_1",
      "volume-title": "Proteorhodopsin phototrophy in the ocean. Nature 411, 786\u2212789",
      "author": "B\u00e9j\u00e0 O.",
      "year": "2001"
    },
    {
      "key": "bi025563xb00007/bi025563xb00007_1",
      "volume": "270",
      "author": "Brown L. S.",
      "year": "1995",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "bi025563xb00008/bi025563xb00008_1",
      "volume-title": "Glutamate-194 to cysteine mutation inhibits fast light-induced proton release in bacteriorhodopsin. Biochemistry 36, 8671\u22128676",
      "author": "Balashov S. P.",
      "year": "1997"
    },
    {
      "key": "bi025563xb00009/bi025563xb00009_1",
      "volume-title": "An efficient site-directed mutagenesis method based on PCR. Biotechniques 17, 657\u2212659",
      "author": "Chen B.",
      "year": "1994"
    },
    {
      "key": "bi025563xb00010/bi025563xb00010_1",
      "volume": "134",
      "author": "Elish M. E.",
      "year": "1988",
      "journal-title": "J. Gen. Microbiol."
    },
    {
      "key": "bi025563xb00011/bi025563xb00011_1",
      "volume-title": "Fourier transform infrared spectra of a late intermediate of the bacteriorhodopsin photocycle suggest transient protonation of Asp-212. Biochemistry 38, 10070\u221210078",
      "author": "Dioumaev A. K.",
      "year": "1999"
    },
    {
      "key": "bi025563xb00012/bi025563xb00012_1",
      "volume-title": "Coupling of the reisomerization of the retinal, proton uptake, and reprotonation of Asp-96 in the N photointermediate of bacteriorhodopsin. Biochemistry 40, 11308\u221211317",
      "author": "Dioumaev A. K.",
      "year": "2001"
    },
    {
      "key": "bi025563xb00013/bi025563xb00013_1",
      "doi-asserted-by": "crossref",
      "first-page": "25",
      "DOI": "10.1016/S0301-4622(96)02268-5",
      "volume": "67",
      "author": "Dioumaev A. K.",
      "year": "1997",
      "journal-title": "Biophys. Chem."
    },
    {
      "key": "bi025563xb00014/bi025563xb00014_1",
      "volume-title": "Existence of a proton-transfer chain in bacteriorhodopsin:\u2009 participation of Glu-194 in the release of protons to the extracellular surface. Biochemistry 37, 2496\u22122506",
      "author": "Dioumaev A. K.",
      "year": "1998"
    },
    {
      "key": "bi025563xb00015/bi025563xb00015_1",
      "volume-title": "Titration of individual components in a mixture with resolution of difference spectra, pKs, and redox transitions. Anal. Chem. 54, 1147\u22121152",
      "author": "Shrager R. I.",
      "year": "1982"
    },
    {
      "key": "bi025563xb00016/bi025563xb00016_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1016/S0006-3495(98)74064-0",
      "volume": "75",
      "author": "Brown L. S.",
      "year": "1998",
      "journal-title": "Biophys. J."
    },
    {
      "key": "bi025563xb00017/bi025563xb00017_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1016/0014-5793(86)81045-6",
      "volume": "208",
      "author": "Grzesiek S.",
      "year": "1986",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "bi025563xb00018/bi025563xb00018_1",
      "volume-title": "Vibrational spectroscopy of bacteriorhodopsin mutants:\u2009 light-driven proton transport 5357 involves protonation changes of aspartic acid residues 85, 96, and 212. Biochemistry 27, 8516\u22128520",
      "author": "Braiman M. S.",
      "year": "1988"
    },
    {
      "key": "bi025563xb00019/bi025563xb00019_1",
      "volume-title": "Proc. Natl. Acad. Sci. U.S.A. 88",
      "author": "Braiman M. S.",
      "year": "1991"
    },
    {
      "key": "bi025563xb00020/bi025563xb00020_1",
      "doi-asserted-by": "crossref",
      "unstructured": "Fahmy, K., Weidlich, O., Engelhard, M., Tittor, J., Oesterhelt, D., and Siebert, F. (1992) Identification of the proton acceptor of Schiff base deprotonation in bacteriorhodopsin:\u2009 a Fourier transform infrared study of the mutant Asp85 \u2192 Glu in its natural lipid environment.Photochem. Photobiol.56, 1073\u22121083.",
      "DOI": "10.1111/j.1751-1097.1992.tb09731.x"
    },
    {
      "key": "bi025563xb00021/bi025563xb00021_1",
      "volume-title": "Proc. Natl. Acad. Sci. U.S.A. 87",
      "author": "Subramaniam S.",
      "year": "1990"
    },
    {
      "key": "bi025563xb00022/bi025563xb00022_1",
      "volume-title": "Proc. Natl. Acad. Sci. U.S.A. 87",
      "author": "Otto H.",
      "year": "1990"
    },
    {
      "key": "bi025563xb00023/bi025563xb00023_1",
      "volume-title": "Rhodopsin-like protein from the purple membrane of Halobacterium halobium. Nat. New Biol. 233, 149\u2212152",
      "author": "Oesterhelt D.",
      "year": "1971"
    },
    {
      "key": "bi025563xb00024/bi025563xb00024_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1016/0005-2728(92)90193-6",
      "volume": "1099",
      "author": "Lanyi J. K.",
      "year": "1992",
      "journal-title": "Biochim. Biophys. Acta"
    },
    {
      "key": "bi025563xb00025/bi025563xb00025_1",
      "volume": "71",
      "author": "Richter H.-T.",
      "year": "1996",
      "journal-title": "Biophys. J."
    },
    {
      "key": "bi025563xb00026/bi025563xb00026_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1016/S0006-3495(96)79591-7",
      "volume": "70",
      "author": "Balashov S. P.",
      "year": "1996",
      "journal-title": "Biophys. J."
    },
    {
      "key": "bi025563xb00027/bi025563xb00027_1",
      "volume": "8",
      "author": "Butt H.-J.",
      "year": "1989",
      "journal-title": "EMBO J."
    },
    {
      "key": "bi025563xb00028/bi025563xb00028_1",
      "volume-title": "Proc. Natl. Acad. Sci. U.S.A. 87",
      "author": "Sawatzki J.",
      "year": "1990"
    },
    {
      "key": "bi025563xb00029/bi025563xb00029_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1021/j100242a011",
      "volume": "87",
      "author": "Kakitani H.",
      "year": "1983",
      "journal-title": "J. Phys. Chem."
    },
    {
      "key": "bi025563xb00030/bi025563xb00030_1",
      "volume": "91",
      "author": "Smith S. O.",
      "year": "1987",
      "journal-title": "J. Phys. Chem."
    },
    {
      "key": "bi025563xb00031/bi025563xb00031_1",
      "volume": "109",
      "author": "Smith S. O.",
      "year": "1987",
      "journal-title": "J. Am. Chem. Soc."
    },
    {
      "key": "bi025563xb00032/bi025563xb00032_1",
      "volume-title": "Chromophore structure in bacteriorhodopsin's O640 photointermediate. Biochemistry 22, 6141\u22126148",
      "author": "Smith S. O.",
      "year": "1983"
    },
    {
      "key": "bi025563xb00033/bi025563xb00033_1",
      "volume-title": "Time-resolved Fourier transform infrared study of structural changes in the last steps of the photocycles of Glu-204 and Leu-93 mutants of bacteriorhodopsin. Biochemistry 36, 5134\u22125141",
      "author": "Kandori H.",
      "year": "1997"
    },
    {
      "key": "bi025563xb00034/bi025563xb00034_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1021/jp971047i",
      "volume": "101",
      "author": "Zscherp C.",
      "year": "1997",
      "journal-title": "J. Phys. Chem. B."
    },
    {
      "key": "bi025563xb00035/bi025563xb00035_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1016/S0006-3495(89)82761-4",
      "volume": "56",
      "author": "V\u00e1r\u00f3 G.",
      "year": "1989",
      "journal-title": "Biophys. J."
    },
    {
      "key": "bi025563xb00036/bi025563xb00036_1",
      "volume-title": "The retinal Schiff base-counterion complex of bacteriorhodopsin:\u2009 changed geometry during the photocycle is a cause of proton transfer to aspartate 85. Biochemistry 33, 12001\u221212011",
      "author": "Brown L. S.",
      "year": "1994"
    },
    {
      "key": "bi025563xb00037/bi025563xb00037_1",
      "volume-title": "Proc. Natl. Acad. Sci. U.S.A. 86",
      "author": "Holz M.",
      "year": "1989"
    },
    {
      "key": "bi025563xb00038/bi025563xb00038_1",
      "volume-title": "Proc. Natl. Acad. Sci. U.S.A. 86",
      "author": "Otto H.",
      "year": "1989"
    },
    {
      "key": "bi025563xb00039/bi025563xb00039_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1002/j.1460-2075.1989.tb08512.x",
      "volume": "8",
      "author": "Tittor J.",
      "year": "1989",
      "journal-title": "EMBO J."
    },
    {
      "key": "bi025563xb00040/bi025563xb00040_1",
      "volume-title": "Water is required for proton transfer from aspartate-96 to the bacteriorhodopsin Schiff base. Biochemistry 30, 10972\u221210979",
      "author": "Cao Y.",
      "year": "1991"
    },
    {
      "key": "bi025563xb00041/bi025563xb00041_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1016/0014-5793(92)81202-W",
      "volume": "313",
      "author": "Drachev L. A.",
      "year": "1992",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "bi025563xb00042/bi025563xb00042_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1021/jp963243f",
      "volume": "101",
      "author": "Delaney J. K.",
      "year": "1997",
      "journal-title": "J. Phys. Chem. B."
    },
    {
      "key": "bi025563xb00043/bi025563xb00043_1",
      "volume-title": "Pathways of proton release in the bacteriorhodopsin photocycle. Biochemistry 31, 8535\u22128543",
      "author": "Zim\u00e1nyi L.",
      "year": "1992"
    },
    {
      "key": "bi025563xb00044/bi025563xb00044_1",
      "doi-asserted-by": "crossref",
      "unstructured": "Cao, Y., Brown, L. S., Needleman, R., and Lanyi, J. K. (1993) Relationship of proton uptake on the cytoplasmic surface and reisomerization of the retinal in the bacteriorhodopsin photocycle:\u2009 An attempt to understand the complex kinetics of the pH changes and the N and O intermediates.Biochemistry32, 10239\u221210248.",
      "DOI": "10.1021/bi00089a046"
    },
    {
      "key": "bi025563xb00045/bi025563xb00045_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1016/S0006-3495(93)81264-5",
      "volume": "65",
      "author": "Hessling B.",
      "year": "1993",
      "journal-title": "Biophys. J."
    },
    {
      "key": "bi025563xb00046/bi025563xb00046_1",
      "volume-title": "FTIR analysis of the SII540 intermediate of sensory rhodopsin II:\u2009 Asp73 is the Schiff base proton acceptor. Biochemistry 39, 2823\u22122830",
      "author": "Bergo V.",
      "year": "2000"
    },
    {
      "key": "bi025563xb00047/bi025563xb00047_1",
      "volume-title": "Conformational changes of bacteriorhodopsin detected by Fourier transform infrared difference spectroscopy. Biochim. Biophys. Res. Commun. 103, 483\u2212489",
      "author": "Rothschild K. J.",
      "year": "1981"
    },
    {
      "key": "bi025563xb00048/bi025563xb00048_1",
      "doi-asserted-by": "crossref",
      "first-page": "87",
      "DOI": "10.1016/0014-5793(82)80021-5",
      "volume": "141",
      "author": "Siebert F.",
      "year": "1982",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "bi025563xb00049/bi025563xb00049_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1002/ijch.199500038",
      "volume": "35",
      "author": "Maeda A.",
      "year": "1995",
      "journal-title": "Israel J. Chem."
    },
    {
      "key": "bi025563xb00050/bi025563xb00050_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1002/ijch.199500029",
      "volume": "35",
      "author": "Althaus T.",
      "year": "1995",
      "journal-title": "Israel J. Chem."
    },
    {
      "key": "bi025563xb00051/bi025563xb00051_1",
      "volume-title": "Fourier transform infrared study of the N intermediate of bacteriorhodopsin. Biochemistry 30, 6548\u22126556",
      "author": "Pfefferl\u00e9 J.-M.",
      "year": "1991"
    },
    {
      "key": "bi025563xb00052/bi025563xb00052_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1016/S0021-9258(18)99128-3",
      "volume": "266",
      "author": "Bousch\u00e9 O.",
      "year": "1991",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "bi025563xb00053/bi025563xb00053_1",
      "volume-title": "Infrared methods for monitoring the protonation state of carboxylic amino acids in the photocycle of bacteriorhodopsin. Biochemistry (Moscow) 66, 1269\u22121276",
      "author": "Dioumaev A. K.",
      "year": "2001"
    },
    {
      "key": "bi025563xb00054/bi025563xb00054_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1016/0016-7037(79)90184-4",
      "volume": "43",
      "author": "Millero F. J.",
      "year": "1979",
      "journal-title": "Geochim. Cosmochim. Acta"
    },
    {
      "key": "bi025563xb00055/bi025563xb00055_1",
      "doi-asserted-by": "crossref",
      "unstructured": "Weidlich, O., and Siebert, F. (1993) Time-resolved step scan FTIR investigations of the transition from KL to L in the bacteriorhodopsin photocycle. Identification of chromophore twists by assigning hydrogen out of plane (HOOP) bending vibrations.Appl. Spectrosc.47, 1394\u22121400.",
      "DOI": "10.1366/0003702934067351"
    },
    {
      "key": "bi025563xb00056/bi025563xb00056_1",
      "volume-title": "Time-resolved infrared spectral analysis of the KL-to-L conversion in the photocycle of bacteriorhodopsin. Biochemistry 32, 867\u2212871",
      "author": "Sasaki J.",
      "year": "1993"
    },
    {
      "key": "bi025563xb00057/bi025563xb00057_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1021/jp961512w",
      "volume": "101",
      "author": "Dioumaev A. K.",
      "year": "1997",
      "journal-title": "J. Phys. Chem. B."
    },
    {
      "key": "bi025563xn00001/bi025563xn00001_1",
      "volume-title": "BR, bacteriorhodopsin",
      "author": "Abbreviations"
    }
  ],
  "container-title": "Biochemistry",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://pubs.acs.org/doi/pdf/10.1021/bi025563x",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        3,
        6
      ]
    ],
    "date-time": "2023-03-06T08:52:45Z",
    "timestamp": 1678092765000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://pubs.acs.org/doi/10.1021/bi025563x"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2002,
        4,
        1
      ]
    ]
  },
  "references-count": 58,
  "journal-issue": {
    "issue": "17",
    "published-print": {
      "date-parts": [
        [
          2002,
          4,
          1
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1021/bi025563x"
  ],
  "URL": "http://dx.doi.org/10.1021/bi025563x",
  "relation": {},
  "ISSN": [
    "0006-2960",
    "1520-4995"
  ],
  "subject": [],
  "container-title-short": "Biochemistry",
  "published": {
    "date-parts": [
      [
        2002,
        4,
        1
      ]
    ]
  }
}