DOI: 10.1021/bc010103m. Polyester Dendritic Systems for Drug Delivery Applications: In Vitro and In Vivo Evaluation

Polyester Dendritic Systems for Drug Delivery Applications: In Vitro and In Vivo Evaluation

10.1021/bc010103m

Crossref journal-article

American Chemical Society (ACS)

Bioconjugate Chemistry (316)

Bibliography

Padilla De JesÃºs, O. L., Ihre, H. R., Gagne, L., FrÃ©chet, J. M. J., & Szoka, F. C. (2002). Polyester Dendritic Systems for Drug Delivery Applications:â In Vitro and In Vivo Evaluation. Bioconjugate Chemistry, 13(3), 453â461.

Authors 5

Omayra L. Padilla De Jesús (first)
Henrik R. Ihre (additional)
Lucie Gagne (additional)
Jean M. J. Fréchet (additional)
Francis C. Szoka (additional)

References 46 Referenced 417

{'key': 'bc010103mb00001/bc010103mb00001_1', 'volume-title': 'New Methods of Drug Delivery. Science 249, 1527−1533', 'author': 'Langer R.', 'year': '1990'} / New Methods of Drug Delivery. Science 249, 1527−1533 by Langer R. (1990)
{'key': 'bc010103mb00002/bc010103mb00002_1', 'volume-title': 'The Role of Polymer Conjugates in the Diagnosis and Treatment of Cancer. S. T. P. Pharma Sciences 6, 237−263', 'author': 'Duncan R.', 'year': '1996'} / The Role of Polymer Conjugates in the Diagnosis and Treatment of Cancer. S. T. P. Pharma Sciences 6, 237−263 by Duncan R. (1996)
{'key': 'bc010103mb00003/bc010103mb00003_1', 'volume-title': 'Conjugates of Anticancer Agents and Polymers:\u2009 Advantages of Macromolecular Therapeutics in Vivo. Bioconjugate Chem. 3, 351−362', 'author': 'Maeda H.', 'year': '1992'} / Conjugates of Anticancer Agents and Polymers: Advantages of Macromolecular Therapeutics in Vivo. Bioconjugate Chem. 3, 351−362 by Maeda H. (1992)
10.1016/S0168-3659(00)00302-3 / J. Control. Release by Mehvar (2000)
{'key': 'bc010103mb00005/bc010103mb00005_1', 'volume-title': 'A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy:\u2009 Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent SMANCS. Cancer Res. 46, 6387−6392', 'author': 'Matsumura R. B.', 'year': '1986'} / A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy: Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent SMANCS. Cancer Res. 46, 6387−6392 by Matsumura R. B. (1986)
{'key': 'bc010103mb00006/bc010103mb00006_1', 'volume-title': 'H+-Induced and Ca-2+-Induced Fusion and Destabilization of Liposomes. Biochemistry 24, 3099−3106', 'author': 'Ellens H.', 'year': '1985'} / H+-Induced and Ca-2+-Induced Fusion and Destabilization of Liposomes. Biochemistry 24, 3099−3106 by Ellens H. (1985)
{'key': 'bc010103mb00007/bc010103mb00007_1', 'volume-title': 'Dendrimers with hydrophobic 461 cores and the formation of supramolecular dendrimer-surfactant assemblies. Langmuir 12, 3136−3141', 'author': 'Watkins D. M.', 'year': '1997'} / Dendrimers with hydrophobic 461 cores and the formation of supramolecular dendrimer-surfactant assemblies. Langmuir 12, 3136−3141 by Watkins D. M. (1997)
{'key': 'bc010103mb00008/bc010103mb00008_1', 'volume': '1', 'author': 'Hawker C. J.', 'year': '1993', 'journal-title': 'J. Chem. Soc., Perkin Trans.'} / J. Chem. Soc., Perkin Trans. by Hawker C. J. (1993)
{'key': 'bc010103mb00009/bc010103mb00009_1', 'volume-title': 'Liposome Encapsulated Doxorubicin Targeted to CD44:\u2009 a Strategy to Kill CD44-Overexpressing Tumor Cells. Cancer Res. 61, 2592−2601', 'author': 'Eliaz R.', 'year': '2001'} / Liposome Encapsulated Doxorubicin Targeted to CD44: a Strategy to Kill CD44-Overexpressing Tumor Cells. Cancer Res. 61, 2592−2601 by Eliaz R. (2001)
10.1097/00001813-199206000-00001 / Drug-polymer Conjugates: Potential for Improved Chemotherapy. Anticancer Drugs 3, 175−210 by Duncan R. (1992)
{'key': 'bc010103mb00011/bc010103mb00011_1', 'volume-title': 'Doxorubicin-loaded Nanospheres bypass Tumour Cell Multidrug Resistance. Biochem. Pharmacol. 44, 509−517', 'author': 'Cuvier C.', 'year': '1992'} / Doxorubicin-loaded Nanospheres bypass Tumour Cell Multidrug Resistance. Biochem. Pharmacol. 44, 509−517 by Cuvier C. (1992)
10.1016/S0168-3659(97)00235-6 / J. Control. Release by Omelyanenko V. (1998)
10.1016/S0168-3659(99)00248-5 / J. Control. Release by Maeda H. (2000)
{'key': 'bc010103mb00014/bc010103mb00014_1', 'volume': '9', 'author': 'Seymour L. W.', 'year': '1992', 'journal-title': 'Crit. Rev. Ther. Drug'} / Crit. Rev. Ther. Drug by Seymour L. W. (1992)
{'key': 'bc010103mb00015/bc010103mb00015_1', 'volume': '31', 'author': 'Seymour L. W.', 'year': '1995', 'journal-title': 'Eur. J. Cancer'} / Eur. J. Cancer by Seymour L. W. (1995)
10.1615/CritRevTherDrugCarrierSyst.v17.i2.20 / Crit. Rev. Ther. Drug by Greenwald R. B. (2000)
{'key': 'bc010103mb00017/bc010103mb00017_1', 'first-page': '94', 'volume': '5', 'author': 'Vasey P. A.', 'year': '1999', 'journal-title': 'Cancer Res.'} / Cancer Res. by Vasey P. A. (1999)
10.1016/S0168-3659(99)00141-8 / J. Control. Release by Ulbrich K. (2000)
{'key': 'bc010103mb00019/bc010103mb00019_1', 'volume-title': 'Designing Dendrimers for Drug Delivery. Pharm. Sci. Technol. Today 2, 393−401', 'author': 'Liu M.', 'year': '1999'} / Designing Dendrimers for Drug Delivery. Pharm. Sci. Technol. Today 2, 393−401 by Liu M. (1999)
{'key': 'bc010103mb00020/bc010103mb00020_1', 'volume': '37', 'author': 'Liu M.', 'year': '1999', 'journal-title': 'J. Polym. Sci., Polym. Chem.'} / J. Polym. Sci., Polym. Chem. by Liu M. (1999)
{'key': 'bc010103mb00021/bc010103mb00021_1', 'volume-title': 'Design of Dendritic Macromolecules Containing Folate or Methotrexate Residues. Bioconjugate Chem. 10, 1115−1121', 'author': 'Kono K.', 'year': '1999'} / Design of Dendritic Macromolecules Containing Folate or Methotrexate Residues. Bioconjugate Chem. 10, 1115−1121 by Kono K. (1999)
{'key': 'bc010103mb00022/bc010103mb00022_1', 'volume-title': "Convergent synthesis and ‘surface' functionalization of a dendritic analogue of poly(ethylene glycol). Chem. Commun. 14, 1329−1330", 'author': 'Grayson S. M.', 'year': '1999'} / Convergent synthesis and ‘surface' functionalization of a dendritic analogue of poly(ethylene glycol). Chem. Commun. 14, 1329−1330 by Grayson S. M. (1999)
{'key': 'bc010103mb00023/bc010103mb00023_1', 'first-page': '131', 'volume': '65', 'author': 'Liu M.', 'year': '2000', 'journal-title': 'J. Control. Release'} / J. Control. Release by Liu M. (2000)
{'key': 'bc010103mb00024/bc010103mb00024_1', 'volume-title': 'Poly(Amidoamine) (PAMAM) Dendrimers: From Biomimicry to Drug Delivery and Biomedical Applications. Drug Discovery Today 6, 427−436', 'author': 'Esfand R.', 'year': '2001'} / Poly(Amidoamine) (PAMAM) Dendrimers: From Biomimicry to Drug Delivery and Biomedical Applications. Drug Discovery Today 6, 427−436 by Esfand R. (2001)
{'key': 'bc010103mb00025/bc010103mb00025_1', 'volume-title': 'Activation of the Complement System by Synthetic DNA Complexes:\u2009 A Potential Barrier for Intravenous Gene Delivery. Hum. Gene Ther. 7, 1441−1450', 'author': 'Plank C.', 'year': '1996'} / Activation of the Complement System by Synthetic DNA Complexes: A Potential Barrier for Intravenous Gene Delivery. Hum. Gene Ther. 7, 1441−1450 by Plank C. (1996)
{'key': 'bc010103mb00026/bc010103mb00026_1', 'volume-title': 'Genealogically Directed Synthesis − Starburst Cascade Dendrimers and Hyperbranched Structures. Top. Curr. Chem. 165, 193−313', 'author': 'Tomalia D. A.', 'year': '1993'} / Genealogically Directed Synthesis − Starburst Cascade Dendrimers and Hyperbranched Structures. Top. Curr. Chem. 165, 193−313 by Tomalia D. A. (1993)
{'key': 'bc010103mb00027/bc010103mb00027_1', 'volume-title': 'Molecular Architecture, and Interfacial Energy. Science 263, 1710−1715.', 'author': 'Fréchet J. M. J.', 'year': '1994'} / Molecular Architecture, and Interfacial Energy. Science 263, 1710−1715. by Fréchet J. M. J. (1994)
{'key': 'bc010103mb00028/bc010103mb00028_1', 'volume-title': 'Synthesis, Perspectives, VCH:\u2009 Weinheim, Germany.', 'author': 'Newkome G. R.', 'year': '1996'} / Synthesis, Perspectives, VCH: Weinheim, Germany. by Newkome G. R. (1996)
10.1295/polymj.17.117 / Polym. J. by Tomalia D. A. (1985)
{'key': 'bc010103mb00030/bc010103mb00030_1', 'volume-title': 'Poliamidoamine Cascade Polymers Mediate Efficient Transfection of Cells in Culture. Bioconjugate Chem. 4, 372−379', 'author': 'Haensler J.', 'year': '1993'} / Poliamidoamine Cascade Polymers Mediate Efficient Transfection of Cells in Culture. Bioconjugate Chem. 4, 372−379 by Haensler J. (1993)
10.1016/S0168-3659(99)00246-1 / J. Control. Release by Malik N. (2000)
{'key': 'bc010103mb00032/bc010103mb00032_1', 'volume': '75', 'author': 'Supattapone S.', 'year': '2001', 'journal-title': 'J. Virol.'} / J. Virol. by Supattapone S. (2001)
{'key': 'bc010103mb00033/bc010103mb00033_1', 'volume-title': 'Proc. Int. Symp. Controlled Release Bioact. Mater. 23', 'author': 'Duncan R.', 'year': '1996'} / Proc. Int. Symp. Controlled Release Bioact. Mater. 23 by Duncan R. (1996)
10.1021/ja00177a027 / J. Am. Chem. Soc. by Hawker C. J. (1990)
Ihre, H. R., Padilla De Jesús, O. L., Szoka, F. C., Jr., and Fréchet, J. M. J. (2002) Polyester Dendritic Systems for Drug Delivery Applications: Design, Synthesis, and Characterization.Bioconjugate Chem. 13, 443−452. (10.1021/bc010102u)
10.1093/jnci/82.13.1107 / J. Natl. Cancer Inst. (Bethesda) by Skehan P. (1990)
{'key': 'bc010103mb00037/bc010103mb00037_1', 'volume': '21', 'author': 'Larwood D. J.', 'year': '1984', 'journal-title': 'J. Label. Comput. Radiopharmaceut.'} / J. Label. Comput. Radiopharmaceut. by Larwood D. J. (1984)
{'key': 'bc010103mb00038/bc010103mb00038_1', 'volume-title': 'Direct nca electrophilic radioiodination of tyrosine analogues', 'author': 'Krummeich C.', 'year': '1994'} / Direct nca electrophilic radioiodination of tyrosine analogues by Krummeich C. (1994)
{'key': 'bc010103mb00039/bc010103mb00039_1', 'volume-title': 'Targeting of drugs to the liver. Semin. Liver Dis. 15, 202−56', 'author': 'Meijer D. K.', 'year': '1995'} / Targeting of drugs to the liver. Semin. Liver Dis. 15, 202−56 by Meijer D. K. (1995)
10.3109/10611869608996824 / J. Drug Target. by Francis G. E. (1996)
{'key': 'bc010103mb00041/bc010103mb00041_1', 'volume-title': 'New Hydrazone Derivatives of Adriamycin and Their Immunoconjugates- a Correlation between Acid Stability and Cytotoxicity. Bioconjugate Chem. 2, 133−141', 'author': 'Kaneko T.', 'year': '1991'} / New Hydrazone Derivatives of Adriamycin and Their Immunoconjugates- a Correlation between Acid Stability and Cytotoxicity. Bioconjugate Chem. 2, 133−141 by Kaneko T. (1991)
{'key': 'bc010103mb00042/bc010103mb00042_1', 'volume-title': 'Chemoselective ligation reactions with proteins, oligosaccharides and cells. TIBTECH 16, 506−511', 'author': 'Lemieux G. A.', 'year': '1998'} / Chemoselective ligation reactions with proteins, oligosaccharides and cells. TIBTECH 16, 506−511 by Lemieux G. A. (1998)
10.1007/978-1-4615-4823-2 / Enzyme Prodrug Strategies for Cancer Therapy by Melton R. G. (1999)
{'key': 'bc010103mb00044/bc010103mb00044_1', 'volume-title': 'Disposition and tumor localization of mitomycin C-Dextran Conjugates in Mice. Pharm. Res. 4, 293−300', 'author': 'Takakura Y.', 'year': '1987'} / Disposition and tumor localization of mitomycin C-Dextran Conjugates in Mice. Pharm. Res. 4, 293−300 by Takakura Y. (1987)
{'key': 'bc010103mb00045/bc010103mb00045_1', 'volume-title': 'Liposomal doxorubicin circumvents PSC 833-free drug interactions, resulting in effective therapy of multidrug-resistant solid tumors. Cancer Res. 57, 5246−5253', 'author': 'Krishna R.', 'year': '1997'} / Liposomal doxorubicin circumvents PSC 833-free drug interactions, resulting in effective therapy of multidrug-resistant solid tumors. Cancer Res. 57, 5246−5253 by Krishna R. (1997)
10.1016/S0168-3659(02)00016-0 / J. Controlled Release by Hovorka O. (2002)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 2:09 a.m.)
Deposited	3 years, 11 months ago (Sept. 22, 2021, 7:31 p.m.)
Indexed	1 week, 6 days ago (Aug. 23, 2025, 9:12 p.m.)
Issued	23 years, 4 months ago (April 24, 2002)
Published	23 years, 4 months ago (April 24, 2002)
Published Online	23 years, 4 months ago (April 24, 2002)
Published Print	23 years, 4 months ago (May 1, 2002)

Funders 0

None

BibTeX

@article{Padilla_De_Jes_s_2002, title={Polyester Dendritic Systems for Drug Delivery Applications: In Vitro and In Vivo Evaluation}, volume={13}, ISSN={1520-4812}, url={http://dx.doi.org/10.1021/bc010103m}, DOI={10.1021/bc010103m}, number={3}, journal={Bioconjugate Chemistry}, publisher={American Chemical Society (ACS)}, author={Padilla De Jesús, Omayra L. and Ihre, Henrik R. and Gagne, Lucie and Fréchet, Jean M. J. and Szoka, Francis C.}, year={2002}, month=apr, pages={453–461} }

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      "volume-title": "The Role of Polymer Conjugates in the Diagnosis and Treatment of Cancer. S. T. P. Pharma Sciences 6, 237\u2212263",
      "author": "Duncan R.",
      "year": "1996"
    },
    {
      "key": "bc010103mb00003/bc010103mb00003_1",
      "volume-title": "Conjugates of Anticancer Agents and Polymers:\u2009 Advantages of Macromolecular Therapeutics in Vivo. Bioconjugate Chem. 3, 351\u2212362",
      "author": "Maeda H.",
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      "key": "bc010103mb00005/bc010103mb00005_1",
      "volume-title": "A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy:\u2009 Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent SMANCS. Cancer Res. 46, 6387\u22126392",
      "author": "Matsumura R. B.",
      "year": "1986"
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    {
      "key": "bc010103mb00006/bc010103mb00006_1",
      "volume-title": "H+-Induced and Ca-2+-Induced Fusion and Destabilization of Liposomes. Biochemistry 24, 3099\u22123106",
      "author": "Ellens H.",
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    },
    {
      "key": "bc010103mb00007/bc010103mb00007_1",
      "volume-title": "Dendrimers with hydrophobic 461 cores and the formation of supramolecular dendrimer-surfactant assemblies. Langmuir 12, 3136\u22123141",
      "author": "Watkins D. M.",
      "year": "1997"
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      "key": "bc010103mb00008/bc010103mb00008_1",
      "volume": "1",
      "author": "Hawker C. J.",
      "year": "1993",
      "journal-title": "J. Chem. Soc., Perkin Trans."
    },
    {
      "key": "bc010103mb00009/bc010103mb00009_1",
      "volume-title": "Liposome Encapsulated Doxorubicin Targeted to CD44:\u2009 a Strategy to Kill CD44-Overexpressing Tumor Cells. Cancer Res. 61, 2592\u22122601",
      "author": "Eliaz R.",
      "year": "2001"
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    },
    {
      "key": "bc010103mb00022/bc010103mb00022_1",
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    },
    {
      "key": "bc010103mb00023/bc010103mb00023_1",
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    },
    {
      "key": "bc010103mb00024/bc010103mb00024_1",
      "volume-title": "Poly(Amidoamine) (PAMAM) Dendrimers: From Biomimicry to Drug Delivery and Biomedical Applications. Drug Discovery Today 6, 427\u2212436",
      "author": "Esfand R.",
      "year": "2001"
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      "key": "bc010103mb00025/bc010103mb00025_1",
      "volume-title": "Activation of the Complement System by Synthetic DNA Complexes:\u2009 A Potential Barrier for Intravenous Gene Delivery. Hum. Gene Ther. 7, 1441\u22121450",
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      "year": "1996"
    },
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      "key": "bc010103mb00026/bc010103mb00026_1",
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    },
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    },
    {
      "key": "bc010103mb00028/bc010103mb00028_1",
      "volume-title": "Synthesis, Perspectives, VCH:\u2009 Weinheim, Germany.",
      "author": "Newkome G. R.",
      "year": "1996"
    },
    {
      "key": "bc010103mb00029/bc010103mb00029_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1295/polymj.17.117",
      "volume": "17",
      "author": "Tomalia D. A.",
      "year": "1985",
      "journal-title": "Polym. J."
    },
    {
      "key": "bc010103mb00030/bc010103mb00030_1",
      "volume-title": "Poliamidoamine Cascade Polymers Mediate Efficient Transfection of Cells in Culture. Bioconjugate Chem. 4, 372\u2212379",
      "author": "Haensler J.",
      "year": "1993"
    },
    {
      "key": "bc010103mb00031/bc010103mb00031_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1016/S0168-3659(99)00246-1",
      "volume": "65",
      "author": "Malik N.",
      "year": "2000",
      "journal-title": "J. Control. Release"
    },
    {
      "key": "bc010103mb00032/bc010103mb00032_1",
      "volume": "75",
      "author": "Supattapone S.",
      "year": "2001",
      "journal-title": "J. Virol."
    },
    {
      "key": "bc010103mb00033/bc010103mb00033_1",
      "volume-title": "Proc. Int. Symp. Controlled Release Bioact. Mater. 23",
      "author": "Duncan R.",
      "year": "1996"
    },
    {
      "key": "bc010103mb00034/bc010103mb00034_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1021/ja00177a027",
      "volume": "112",
      "author": "Hawker C. J.",
      "year": "1990",
      "journal-title": "J. Am. Chem. Soc."
    },
    {
      "key": "bc010103mb00035/bc010103mb00035_1",
      "doi-asserted-by": "crossref",
      "unstructured": "Ihre, H. R., Padilla De Jes\u00fas, O. L., Szoka, F. C., Jr., and Fr\u00e9chet, J. M. J. (2002) Polyester Dendritic Systems for Drug Delivery Applications:\u2009 Design, Synthesis, and Characterization.Bioconjugate Chem. 13, 443\u2212452.",
      "DOI": "10.1021/bc010102u"
    },
    {
      "key": "bc010103mb00036/bc010103mb00036_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1093/jnci/82.13.1107",
      "volume": "82",
      "author": "Skehan P.",
      "year": "1990",
      "journal-title": "J. Natl. Cancer Inst. (Bethesda)"
    },
    {
      "key": "bc010103mb00037/bc010103mb00037_1",
      "volume": "21",
      "author": "Larwood D. J.",
      "year": "1984",
      "journal-title": "J. Label. Comput. Radiopharmaceut."
    },
    {
      "key": "bc010103mb00038/bc010103mb00038_1",
      "volume-title": "Direct nca electrophilic radioiodination of tyrosine analogues",
      "author": "Krummeich C.",
      "year": "1994"
    },
    {
      "key": "bc010103mb00039/bc010103mb00039_1",
      "volume-title": "Targeting of drugs to the liver. Semin. Liver Dis. 15, 202\u221256",
      "author": "Meijer D. K.",
      "year": "1995"
    },
    {
      "key": "bc010103mb00040/bc010103mb00040_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.3109/10611869608996824",
      "volume": "3",
      "author": "Francis G. E.",
      "year": "1996",
      "journal-title": "J. Drug Target."
    },
    {
      "key": "bc010103mb00041/bc010103mb00041_1",
      "volume-title": "New Hydrazone Derivatives of Adriamycin and Their Immunoconjugates- a Correlation between Acid Stability and Cytotoxicity. Bioconjugate Chem. 2, 133\u2212141",
      "author": "Kaneko T.",
      "year": "1991"
    },
    {
      "key": "bc010103mb00042/bc010103mb00042_1",
      "volume-title": "Chemoselective ligation reactions with proteins, oligosaccharides and cells. TIBTECH 16, 506\u2212511",
      "author": "Lemieux G. A.",
      "year": "1998"
    },
    {
      "key": "bc010103mb00043/bc010103mb00043_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1007/978-1-4615-4823-2",
      "volume-title": "Enzyme Prodrug Strategies for Cancer Therapy",
      "author": "Melton R. G.",
      "year": "1999"
    },
    {
      "key": "bc010103mb00044/bc010103mb00044_1",
      "volume-title": "Disposition and tumor localization of mitomycin C-Dextran Conjugates in Mice. Pharm. Res. 4, 293\u2212300",
      "author": "Takakura Y.",
      "year": "1987"
    },
    {
      "key": "bc010103mb00045/bc010103mb00045_1",
      "volume-title": "Liposomal doxorubicin circumvents PSC 833-free drug interactions, resulting in effective therapy of multidrug-resistant solid tumors. Cancer Res. 57, 5246\u22125253",
      "author": "Krishna R.",
      "year": "1997"
    },
    {
      "key": "bc010103mb00046/bc010103mb00046_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1016/S0168-3659(02)00016-0",
      "volume": "80",
      "author": "Hovorka O.",
      "year": "2002",
      "journal-title": "J. Controlled Release"
    }
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