DOI: 10.1021/bc0000637. A Nonviral DNA Delivery System Based on Surface Modified Silica-Nanoparticles Can Efficiently Transfect Cells in Vitro

A Nonviral DNA Delivery System Based on Surface Modified Silica-Nanoparticles Can Efficiently Transfect Cells in Vitro

10.1021/bc0000637

Crossref journal-article

American Chemical Society (ACS)

Bioconjugate Chemistry (316)

Bibliography

Kneuer, C., Sameti, M., Bakowsky, U., Schiestel, T., Schirra, H., Schmidt, H., & Lehr, C.-M. (2000). A Nonviral DNA Delivery System Based on Surface Modified Silica-Nanoparticles Can Efficiently Transfect Cells in Vitro. Bioconjugate Chemistry, 11(6), 926â932.

Authors 7

Carsten Kneuer (first)
Mohammad Sameti (additional)
Udo Bakowsky (additional)
Thomas Schiestel (additional)
Hermann Schirra (additional)
Helmut Schmidt (additional)
Claus-Michael Lehr (additional)

References 31 Referenced 302

{'key': 'bc0000637b00001/bc0000637b00001_1', 'volume-title': 'Stable and monodisperse lipoplex formulations for gene delivery. Gene Ther. 5, 1272−1282', 'author': 'Zelphati O.', 'year': '1998'} / Stable and monodisperse lipoplex formulations for gene delivery. Gene Ther. 5, 1272−1282 by Zelphati O. (1998)
{'key': 'bc0000637b00002/bc0000637b00002_1', 'volume-title': 'Proc. Natl. Acad. Sci. U.S.A. 92', 'author': 'Boussif O.', 'year': '1995'} / Proc. Natl. Acad. Sci. U.S.A. 92 by Boussif O. (1995)
{'key': 'bc0000637b00003/bc0000637b00003_1', 'volume-title': 'Polyamidoamine Cascade Polymers Mediate Efficient transfection of Cells in Culture. Bioconjugate Chem. 4, 372−379', 'author': 'Haensler J.', 'year': '1993'} / Polyamidoamine Cascade Polymers Mediate Efficient transfection of Cells in Culture. Bioconjugate Chem. 4, 372−379 by Haensler J. (1993)
{'key': 'bc0000637b00004/bc0000637b00004_1', 'volume-title': 'A novel DNA-peptide complex for efficient gene transfer and expression in mammalian cells. Gene Ther. 3, 448−457', 'author': 'Gottschalk S.', 'year': '1996'} / A novel DNA-peptide complex for efficient gene transfer and expression in mammalian cells. Gene Ther. 3, 448−457 by Gottschalk S. (1996)
{'key': 'bc0000637b00005/bc0000637b00005_1', 'volume-title': 'Proc. Natl. Acad. Sci. U.S.A. 95', 'author': 'Blessing T.', 'year': '1998'} / Proc. Natl. Acad. Sci. U.S.A. 95 by Blessing T. (1998)
{'key': 'bc0000637b00006/bc0000637b00006_1', 'volume-title': 'Proc. Natl. Acad. Sci. U.S.A. 87', 'author': 'Wagner E.', 'year': '1990'} / Proc. Natl. Acad. Sci. U.S.A. 87 by Wagner E. (1990)
{'key': 'bc0000637b00007/bc0000637b00007_1', 'volume-title': 'Proc. Natl. Acad. Sci. U.S.A. 89', 'author': 'Wagner E.', 'year': '1992'} / Proc. Natl. Acad. Sci. U.S.A. 89 by Wagner E. (1992)
{'key': 'bc0000637b00008/bc0000637b00008_1', 'volume-title': 'High efficiency polyoma DNA transfection of chloroquine treated cells. Nucleic Acids Res. 11, 1295−1308', 'author': 'Luthman H.', 'year': '1983'} / High efficiency polyoma DNA transfection of chloroquine treated cells. Nucleic Acids Res. 11, 1295−1308 by Luthman H. (1983)
{'key': 'bc0000637b00009/bc0000637b00009_1', 'volume-title': 'Proc. Natl. Acad. Sci. U.S.A. 89', 'author': 'Wagner E.', 'year': '1992'} / Proc. Natl. Acad. Sci. U.S.A. 89 by Wagner E. (1992)
10.1073/pnas.96.1.91 / Proc. Natl. Acad. Sci. U.S.A. by Zanta M. A. (1999)
{'key': 'bc0000637b00011/bc0000637b00011_1', 'first-page': '64', 'volume': '34', 'author': 'Pouton C. W.', 'year': '1998', 'journal-title': 'Adv. Drug Delivery Rev.'} / Adv. Drug Delivery Rev. by Pouton C. W. (1998)
10.1006/bbrc.1997.6568 / Biochem. Biophys. Res. Commun. by Mizuguchi H. (1997)
{'key': 'bc0000637b00013/bc0000637b00013_1', 'first-page': '20', 'volume': '34', 'author': 'Pouton C. W.', 'year': '1998', 'journal-title': 'Adv. Drug Delivery Rev.'} / Adv. Drug Delivery Rev. by Pouton C. W. (1998)
10.1016/S0169-409X(98)00005-2 / Adv. Drug Delivery Rev. by Plank C. (1998)
10.1016/S0169-409X(98)00004-0 / Adv. Drug Delivery Rev. by Mönkkönen J. (1998)
Cotten, M. (1994) Adenovirus-Augmented, Receptor-Mediated Gene Delivery and some Solutions to the Common Toxicity Problems. InThe Molecular Repertoire of Adenoviruses III - Biology and Pathogenesis. Current Topics in Microbiology and Immunology199(W. Doerfler and P. Möhm, Eds.) pp 283−295, Springer-Verlag, Berlin. (10.1007/978-3-642-79586-2_13)
{'key': 'bc0000637b00017/bc0000637b00017_1', 'volume-title': 'Int. J. Pharm', 'author': 'Kneuer C.', 'year': '2000'} / Int. J. Pharm by Kneuer C. (2000)
{'key': 'bc0000637b00018/bc0000637b00018_1', 'volume-title': 'Effect of Size and serum Proteins on Transfection Efficiency of Poly((2-dimethylamino)ethyl Methacrylate)-Plasmid Nanoparticles. Pharm. Res. 13, 1038−1042', 'author': 'Cherng J. Y.', 'year': '1996'} / Effect of Size and serum Proteins on Transfection Efficiency of Poly((2-dimethylamino)ethyl Methacrylate)-Plasmid Nanoparticles. Pharm. Res. 13, 1038−1042 by Cherng J. Y. (1996)
{'key': 'bc0000637b00019/bc0000637b00019_1', 'volume-title': 'Improved packing of poly(ethylenimine)/DNA complexes increases transfection efficiency. Gene Ther. 6, 1380−1388', 'author': 'Godbey W. T.', 'year': '1999'} / Improved packing of poly(ethylenimine)/DNA complexes increases transfection efficiency. Gene Ther. 6, 1380−1388 by Godbey W. T. (1999)
{'key': 'bc0000637b00020/bc0000637b00020_1', 'first-page': '64', 'volume': '16', 'author': 'Wu Y. L.', 'year': '1993', 'journal-title': 'Shih Yen Sheng Wu Hsueh Pao'} / Shih Yen Sheng Wu Hsueh Pao by Wu Y. L. (1993)
10.1016/0014-5793(94)80185-1 / FEBS Lett. by Yaroslavov A. A. (1994)
{'key': 'bc0000637b00022/bc0000637b00022_1', 'first-page': '36', 'volume': '1110', 'author': 'Takahashi H.', 'year': '1992', 'journal-title': 'Biochim. Biophys. Acta'} / Biochim. Biophys. Acta by Takahashi H. (1992)
{'key': 'bc0000637b00023/bc0000637b00023_1', 'volume-title': 'Synthesis of polyallylamine derivatives and their use as gene transfer vectors in vitro. Bioconjugate Chem. 10, 877−883', 'author': 'Boussif O.', 'year': '1999'} / Synthesis of polyallylamine derivatives and their use as gene transfer vectors in vitro. Bioconjugate Chem. 10, 877−883 by Boussif O. (1999)
{'key': 'bc0000637b00024/bc0000637b00024_1', 'volume-title': 'Accurate determination of DNA content in single cell nuclei stained with Hoechst 33258 fluorochrome at high salt concentration. Histochemistry 87 (4), 331−338', 'author': 'Araki T.', 'year': '1987'} / Accurate determination of DNA content in single cell nuclei stained with Hoechst 33258 fluorochrome at high salt concentration. Histochemistry 87 (4), 331−338 by Araki T. (1987)
{'key': 'bc0000637b00025/bc0000637b00025_1', 'volume-title': 'Nanoparticle DNA Carrier with Poly(l-lysine) Grafted Polysaccharide Coplolymer and Poly(d,l-lactic acid). Bioconjugate Chem. 8, 735−742', 'author': 'Maruyama A.', 'year': '1997'} / Nanoparticle DNA Carrier with Poly(l-lysine) Grafted Polysaccharide Coplolymer and Poly(d,l-lactic acid). Bioconjugate Chem. 8, 735−742 by Maruyama A. (1997)
{'key': 'bc0000637b00026/bc0000637b00026_1', 'volume-title': 'Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery. Gene Ther. 6, 643−650', 'author': 'Dash P. R.', 'year': '1999'} / Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery. Gene Ther. 6, 643−650 by Dash P. R. (1999)
{'key': 'bc0000637b00027/bc0000637b00027_1', 'volume-title': 'On the mechanism of DNA transfection:\u2009 efficient gene transfer without viruses. Gene Ther. 4, 1313−1321', 'author': 'Coonrod A.', 'year': '1997'} / On the mechanism of DNA transfection: efficient gene transfer without viruses. Gene Ther. 4, 1313−1321 by Coonrod A. (1997)
{'key': 'bc0000637b00028/bc0000637b00028_1', 'volume-title': 'Chloroquine and amphipathic peptide helices show synergistic transfection in vitro. Gene Ther. 5, 409−414', 'author': 'Wolfert M. A.', 'year': '1998'} / Chloroquine and amphipathic peptide helices show synergistic transfection in vitro. Gene Ther. 5, 409−414 by Wolfert M. A. (1998)
{'key': 'bc0000637b00029/bc0000637b00029_1', 'volume-title': 'Putative Role of Chloroquine in Gene Transfer into a Human Hepatoma Cell Line by DNA/Lactosylated Polylysine Complexes. Exp. Cell. Res. 225, 186−194', 'author': 'Erbacher P.', 'year': '1996'} / Putative Role of Chloroquine in Gene Transfer into a Human Hepatoma Cell Line by DNA/Lactosylated Polylysine Complexes. Exp. Cell. Res. 225, 186−194 by Erbacher P. (1996)
{'key': 'bc0000637b00030/bc0000637b00030_1', 'volume-title': 'The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther. 4, 823−832', 'author': 'Tang M. X.', 'year': '1999'} / The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther. 4, 823−832 by Tang M. X. (1999)
{'key': 'bc0000637b00031/bc0000637b00031_1', 'volume-title': 'Calpain Contributes to Silica-Induced IκB-α Degradation and Nuclear factor-κB Activation. Arch. Biochem. Biophys. 342 (2), 383−388', 'author': 'Chen F.', 'year': '1997'} / Calpain Contributes to Silica-Induced IκB-α Degradation and Nuclear factor-κB Activation. Arch. Biochem. Biophys. 342 (2), 383−388 by Chen F. (1997)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 1:51 a.m.)
Deposited	2 years, 5 months ago (March 14, 2023, 7:04 a.m.)
Indexed	3 hours, 10 minutes ago (Sept. 3, 2025, 6:10 a.m.)
Issued	24 years, 10 months ago (Nov. 1, 2000)
Published	24 years, 10 months ago (Nov. 1, 2000)
Published Online	24 years, 10 months ago (Nov. 3, 2000)
Published Print	24 years, 10 months ago (Nov. 1, 2000)

Funders 0

None

BibTeX

@article{Kneuer_2000, title={A Nonviral DNA Delivery System Based on Surface Modified Silica-Nanoparticles Can Efficiently Transfect Cells in Vitro}, volume={11}, ISSN={1520-4812}, url={http://dx.doi.org/10.1021/bc0000637}, DOI={10.1021/bc0000637}, number={6}, journal={Bioconjugate Chemistry}, publisher={American Chemical Society (ACS)}, author={Kneuer, Carsten and Sameti, Mohammad and Bakowsky, Udo and Schiestel, Thomas and Schirra, Hermann and Schmidt, Helmut and Lehr, Claus-Michael}, year={2000}, month=nov, pages={926–932} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        9,
        3
      ]
    ],
    "date-time": "2025-09-03T10:10:27Z",
    "timestamp": 1756894227467
  },
  "reference-count": 31,
  "publisher": "American Chemical Society (ACS)",
  "issue": "6",
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2000,
        11,
        1
      ]
    ]
  },
  "DOI": "10.1021/bc0000637",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        26
      ]
    ],
    "date-time": "2002-07-26T05:51:32Z",
    "timestamp": 1027662692000
  },
  "page": "926-932",
  "source": "Crossref",
  "is-referenced-by-count": 302,
  "title": "A Nonviral DNA Delivery System Based on Surface Modified Silica-Nanoparticles Can Efficiently Transfect Cells in Vitro",
  "prefix": "10.1021",
  "volume": "11",
  "author": [
    {
      "given": "Carsten",
      "family": "Kneuer",
      "sequence": "first",
      "affiliation": [
        {
          "name": "Department of Biopharmaceutics and Pharmaceutical Technology, Saarland University, 66041 Saarbr\u00fccken, Germany, Institute for New Materials gemGmbH, Im Stadtwald, 66123 Saarbr\u00fccken, Germany, and Department of Physiological Chemistry, University of Groningen, Groningen, The Netherlands"
        }
      ]
    },
    {
      "given": "Mohammad",
      "family": "Sameti",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Biopharmaceutics and Pharmaceutical Technology, Saarland University, 66041 Saarbr\u00fccken, Germany, Institute for New Materials gemGmbH, Im Stadtwald, 66123 Saarbr\u00fccken, Germany, and Department of Physiological Chemistry, University of Groningen, Groningen, The Netherlands"
        }
      ]
    },
    {
      "given": "Udo",
      "family": "Bakowsky",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Biopharmaceutics and Pharmaceutical Technology, Saarland University, 66041 Saarbr\u00fccken, Germany, Institute for New Materials gemGmbH, Im Stadtwald, 66123 Saarbr\u00fccken, Germany, and Department of Physiological Chemistry, University of Groningen, Groningen, The Netherlands"
        }
      ]
    },
    {
      "given": "Thomas",
      "family": "Schiestel",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Biopharmaceutics and Pharmaceutical Technology, Saarland University, 66041 Saarbr\u00fccken, Germany, Institute for New Materials gemGmbH, Im Stadtwald, 66123 Saarbr\u00fccken, Germany, and Department of Physiological Chemistry, University of Groningen, Groningen, The Netherlands"
        }
      ]
    },
    {
      "given": "Hermann",
      "family": "Schirra",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Biopharmaceutics and Pharmaceutical Technology, Saarland University, 66041 Saarbr\u00fccken, Germany, Institute for New Materials gemGmbH, Im Stadtwald, 66123 Saarbr\u00fccken, Germany, and Department of Physiological Chemistry, University of Groningen, Groningen, The Netherlands"
        }
      ]
    },
    {
      "given": "Helmut",
      "family": "Schmidt",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Biopharmaceutics and Pharmaceutical Technology, Saarland University, 66041 Saarbr\u00fccken, Germany, Institute for New Materials gemGmbH, Im Stadtwald, 66123 Saarbr\u00fccken, Germany, and Department of Physiological Chemistry, University of Groningen, Groningen, The Netherlands"
        }
      ]
    },
    {
      "given": "Claus-Michael",
      "family": "Lehr",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Biopharmaceutics and Pharmaceutical Technology, Saarland University, 66041 Saarbr\u00fccken, Germany, Institute for New Materials gemGmbH, Im Stadtwald, 66123 Saarbr\u00fccken, Germany, and Department of Physiological Chemistry, University of Groningen, Groningen, The Netherlands"
        }
      ]
    }
  ],
  "member": "316",
  "published-online": {
    "date-parts": [
      [
        2000,
        11,
        3
      ]
    ]
  },
  "reference": [
    {
      "key": "bc0000637b00001/bc0000637b00001_1",
      "volume-title": "Stable and monodisperse lipoplex formulations for gene delivery. Gene Ther. 5, 1272\u22121282",
      "author": "Zelphati O.",
      "year": "1998"
    },
    {
      "key": "bc0000637b00002/bc0000637b00002_1",
      "volume-title": "Proc. Natl. Acad. Sci. U.S.A. 92",
      "author": "Boussif O.",
      "year": "1995"
    },
    {
      "key": "bc0000637b00003/bc0000637b00003_1",
      "volume-title": "Polyamidoamine Cascade Polymers Mediate Efficient transfection of Cells in Culture. Bioconjugate Chem. 4, 372\u2212379",
      "author": "Haensler J.",
      "year": "1993"
    },
    {
      "key": "bc0000637b00004/bc0000637b00004_1",
      "volume-title": "A novel DNA-peptide complex for efficient gene transfer and expression in mammalian cells. Gene Ther. 3, 448\u2212457",
      "author": "Gottschalk S.",
      "year": "1996"
    },
    {
      "key": "bc0000637b00005/bc0000637b00005_1",
      "volume-title": "Proc. Natl. Acad. Sci. U.S.A. 95",
      "author": "Blessing T.",
      "year": "1998"
    },
    {
      "key": "bc0000637b00006/bc0000637b00006_1",
      "volume-title": "Proc. Natl. Acad. Sci. U.S.A. 87",
      "author": "Wagner E.",
      "year": "1990"
    },
    {
      "key": "bc0000637b00007/bc0000637b00007_1",
      "volume-title": "Proc. Natl. Acad. Sci. U.S.A. 89",
      "author": "Wagner E.",
      "year": "1992"
    },
    {
      "key": "bc0000637b00008/bc0000637b00008_1",
      "volume-title": "High efficiency polyoma DNA transfection of chloroquine treated cells. Nucleic Acids Res. 11, 1295\u22121308",
      "author": "Luthman H.",
      "year": "1983"
    },
    {
      "key": "bc0000637b00009/bc0000637b00009_1",
      "volume-title": "Proc. Natl. Acad. Sci. U.S.A. 89",
      "author": "Wagner E.",
      "year": "1992"
    },
    {
      "key": "bc0000637b00010/bc0000637b00010_1",
      "doi-asserted-by": "crossref",
      "first-page": "96",
      "DOI": "10.1073/pnas.96.1.91",
      "volume": "96",
      "author": "Zanta M. A.",
      "year": "1999",
      "journal-title": "Proc. Natl. Acad. Sci. U.S.A."
    },
    {
      "key": "bc0000637b00011/bc0000637b00011_1",
      "first-page": "64",
      "volume": "34",
      "author": "Pouton C. W.",
      "year": "1998",
      "journal-title": "Adv. Drug Delivery Rev."
    },
    {
      "key": "bc0000637b00012/bc0000637b00012_1",
      "doi-asserted-by": "crossref",
      "first-page": "18",
      "DOI": "10.1006/bbrc.1997.6568",
      "volume": "234",
      "author": "Mizuguchi H.",
      "year": "1997",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "bc0000637b00013/bc0000637b00013_1",
      "first-page": "20",
      "volume": "34",
      "author": "Pouton C. W.",
      "year": "1998",
      "journal-title": "Adv. Drug Delivery Rev."
    },
    {
      "key": "bc0000637b00014/bc0000637b00014_1",
      "doi-asserted-by": "crossref",
      "first-page": "36",
      "DOI": "10.1016/S0169-409X(98)00005-2",
      "volume": "34",
      "author": "Plank C.",
      "year": "1998",
      "journal-title": "Adv. Drug Delivery Rev."
    },
    {
      "key": "bc0000637b00015/bc0000637b00015_1",
      "doi-asserted-by": "crossref",
      "first-page": "50",
      "DOI": "10.1016/S0169-409X(98)00004-0",
      "volume": "34",
      "author": "M\u00f6nkk\u00f6nen J.",
      "year": "1998",
      "journal-title": "Adv. Drug Delivery Rev."
    },
    {
      "key": "bc0000637b00016/bc0000637b00016_1",
      "doi-asserted-by": "crossref",
      "unstructured": "Cotten, M. (1994) Adenovirus-Augmented, Receptor-Mediated Gene Delivery and some Solutions to the Common Toxicity Problems. InThe Molecular Repertoire of Adenoviruses III - Biology and Pathogenesis. Current Topics in Microbiology and Immunology199(W. Doerfler and P. M\u00f6hm, Eds.) pp 283\u2212295, Springer-Verlag, Berlin.",
      "DOI": "10.1007/978-3-642-79586-2_13"
    },
    {
      "key": "bc0000637b00017/bc0000637b00017_1",
      "volume-title": "Int. J. Pharm",
      "author": "Kneuer C.",
      "year": "2000"
    },
    {
      "key": "bc0000637b00018/bc0000637b00018_1",
      "volume-title": "Effect of Size and serum Proteins on Transfection Efficiency of Poly((2-dimethylamino)ethyl Methacrylate)-Plasmid Nanoparticles. Pharm. Res. 13, 1038\u22121042",
      "author": "Cherng J. Y.",
      "year": "1996"
    },
    {
      "key": "bc0000637b00019/bc0000637b00019_1",
      "volume-title": "Improved packing of poly(ethylenimine)/DNA complexes increases transfection efficiency. Gene Ther. 6, 1380\u22121388",
      "author": "Godbey W. T.",
      "year": "1999"
    },
    {
      "key": "bc0000637b00020/bc0000637b00020_1",
      "first-page": "64",
      "volume": "16",
      "author": "Wu Y. L.",
      "year": "1993",
      "journal-title": "Shih Yen Sheng Wu Hsueh Pao"
    },
    {
      "key": "bc0000637b00021/bc0000637b00021_1",
      "doi-asserted-by": "crossref",
      "DOI": "10.1016/0014-5793(94)80185-1",
      "volume": "340",
      "author": "Yaroslavov A. A.",
      "year": "1994",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "bc0000637b00022/bc0000637b00022_1",
      "first-page": "36",
      "volume": "1110",
      "author": "Takahashi H.",
      "year": "1992",
      "journal-title": "Biochim. Biophys. Acta"
    },
    {
      "key": "bc0000637b00023/bc0000637b00023_1",
      "volume-title": "Synthesis of polyallylamine derivatives and their use as gene transfer vectors in vitro. Bioconjugate Chem. 10, 877\u2212883",
      "author": "Boussif O.",
      "year": "1999"
    },
    {
      "key": "bc0000637b00024/bc0000637b00024_1",
      "volume-title": "Accurate determination of DNA content in single cell nuclei stained with Hoechst 33258 fluorochrome at high salt concentration. Histochemistry 87 (4), 331\u2212338",
      "author": "Araki T.",
      "year": "1987"
    },
    {
      "key": "bc0000637b00025/bc0000637b00025_1",
      "volume-title": "Nanoparticle DNA Carrier with Poly(l-lysine) Grafted Polysaccharide Coplolymer and Poly(d,l-lactic acid). Bioconjugate Chem. 8, 735\u2212742",
      "author": "Maruyama A.",
      "year": "1997"
    },
    {
      "key": "bc0000637b00026/bc0000637b00026_1",
      "volume-title": "Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery. Gene Ther. 6, 643\u2212650",
      "author": "Dash P. R.",
      "year": "1999"
    },
    {
      "key": "bc0000637b00027/bc0000637b00027_1",
      "volume-title": "On the mechanism of DNA transfection:\u2009 efficient gene transfer without viruses. Gene Ther. 4, 1313\u22121321",
      "author": "Coonrod A.",
      "year": "1997"
    },
    {
      "key": "bc0000637b00028/bc0000637b00028_1",
      "volume-title": "Chloroquine and amphipathic peptide helices show synergistic transfection in vitro. Gene Ther. 5, 409\u2212414",
      "author": "Wolfert M. A.",
      "year": "1998"
    },
    {
      "key": "bc0000637b00029/bc0000637b00029_1",
      "volume-title": "Putative Role of Chloroquine in Gene Transfer into a Human Hepatoma Cell Line by DNA/Lactosylated Polylysine Complexes. Exp. Cell. Res. 225, 186\u2212194",
      "author": "Erbacher P.",
      "year": "1996"
    },
    {
      "key": "bc0000637b00030/bc0000637b00030_1",
      "volume-title": "The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther. 4, 823\u2212832",
      "author": "Tang M. X.",
      "year": "1999"
    },
    {
      "key": "bc0000637b00031/bc0000637b00031_1",
      "volume-title": "Calpain Contributes to Silica-Induced I\u03baB-\u03b1 Degradation and Nuclear factor-\u03baB Activation. Arch. Biochem. Biophys. 342 (2), 383\u2212388",
      "author": "Chen F.",
      "year": "1997"
    }
  ],
  "container-title": "Bioconjugate Chemistry",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://pubs.acs.org/doi/pdf/10.1021/bc0000637",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        3,
        14
      ]
    ],
    "date-time": "2023-03-14T11:04:54Z",
    "timestamp": 1678791894000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://pubs.acs.org/doi/10.1021/bc0000637"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2000,
        11,
        1
      ]
    ]
  },
  "references-count": 31,
  "journal-issue": {
    "issue": "6",
    "published-print": {
      "date-parts": [
        [
          2000,
          11,
          1
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1021/bc0000637"
  ],
  "URL": "http://dx.doi.org/10.1021/bc0000637",
  "relation": {},
  "ISSN": [
    "1043-1802",
    "1520-4812"
  ],
  "subject": [],
  "container-title-short": "Bioconjugate Chem.",
  "published": {
    "date-parts": [
      [
        2000,
        11,
        1
      ]
    ]
  }
}