DOI: 10.1017/s0950268800057216. The coccoid forms of<i>Helicobacter pylori</i>. Criteria for their viability

The coccoid forms ofHelicobacter pylori. Criteria for their viability

10.1017/s0950268800057216

Crossref journal-article

Cambridge University Press (CUP)

Epidemiology and Infection (56)

Abstract

SummaryThe fact thatHelicobacter pylorican revert to a coccoid form has stimulated speculation about its role in transmission and as a possible cause of reinfection in duodenal ulcer disease. Bismuth subcitrate (32 μg/ml), bismuth subsalicylate (64 μg/ml), amoxicillin (0·05 μg/ml) and erythromycin (4 μg/ml) inhibited the growth ofH. pyloriand stimulated the formation the formation of basically respiring but non-culturable coccoid structures. The presence of polyphosphates as energy and phosphorus source permits a certain level of endogenous metabolism to preserve RNA and DNA, as well as structural components like cell wall, cell membrane and cytoplasma for at least 3 months. However, the applied standard laboratory methods were insufficient for regrowth ofH. pyloriout of the coccoid form.

Bibliography

Bode, G., Mauch, F., & Malfertheiner, P. (1993). The coccoid forms ofHelicobacter pylori. Criteria for their viability. Epidemiology and Infection, 111(3), 483â490.

Authors 3

G. Bode (first)
F. Mauch (additional)
P. Malfertheiner (additional)

References 31 Referenced 167

10.1099/00222615-38-1-6
{'key': 'S0950268800057216_ref030', 'first-page': '1545', 'article-title': 'Drug therapy for Helicobacter pylori infection: problems and pitfalls', 'volume': '85', 'author': 'Glupczynski', 'year': '1990', 'journal-title': 'Am J Gastroenterol'} / Am J Gastroenterol / Drug therapy for Helicobacter pylori infection: problems and pitfalls by Glupczynski (1990)
10.1139/m88-076
{'key': 'S0950268800057216_ref027', 'first-page': '115', 'article-title': 'Effects of acquatic environmental stress on enteric bacterial pathogens', 'volume': '70', 'author': 'McFeters', 'year': '1991', 'journal-title': 'J Appl Bacteriol'} / J Appl Bacteriol / Effects of acquatic environmental stress on enteric bacterial pathogens by McFeters (1991)
10.1128/AEM.55.2.495-499.1989 / Appl Environ Microbiol / In situ survival of Vibrio cholerae and Escherichia coli in a tropical rain forest watershed by Perez-Rosas (1989)
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{'key': 'S0950268800057216_ref013', 'first-page': '99', 'volume-title': 'Principles and techniques of electron microscopy', 'volume': '2', 'author': 'Haschemeyer', 'year': '1972'} / Principles and techniques of electron microscopy by Haschemeyer (1972)
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{'key': 'S0950268800057216_ref021', 'first-page': '179', 'article-title': 'Polymorphism in Helicobacter pylori – a key function for recurrent infection ?', 'volume': '87', 'author': 'Bode', 'year': '1992', 'journal-title': 'Med Klin'} / Med Klin / Polymorphism in Helicobacter pylori – a key function for recurrent infection ? by Bode (1992)
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10.1136/jcp.43.7.609-b
10.1128/AEM.57.11.3388-3389.1991 / Appl Environ Microbiol / Recovery of injured Campylobacter jejuni cells after animal passage by Saha (1991)
10.1128/AEM.52.3.531-538.1986 / Appl Environ Microbiol / Viable but nonculturable stage of Campylobacter jejuni and its role in survival in the natural aquatic environment by Rollins (1986)
10.1128/IAI.60.2.606-611.1992 / Infect Immun / Helicobacter mustelae isolation from feces of ferrets: evidence to support fecal–oral transmission of a gastric Helicobacter by Fox (1992)
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10.1128/JB.164.1.338-343.1985 / J Bacteriol / Morphological forms and viability of Campylobacter species studied by electron microscopy by Ng (1985)
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15. Bode G , Mauch F , Ditschuneit H , Malfertheiner P . Identification and characterization of polyphosphates in Helicobacter pylori. In press.
{'key': 'S0950268800057216_ref017', 'first-page': '35', 'article-title': 'Coccoid forms of Helicobacter pylori are viable', 'volume': '23', 'author': 'Bode', 'year': '1991', 'journal-title': 'Ital J Gastroenterol'} / Ital J Gastroenterol / Coccoid forms of Helicobacter pylori are viable by Bode (1991)
10.1017/S095026880004872X

Dates

Type	When
Created	16 years, 3 months ago (May 15, 2009, 4:50 a.m.)
Deposited	5 years, 3 months ago (May 18, 2020, 1:04 a.m.)
Indexed	15 hours, 1 minute ago (Sept. 3, 2025, 6:51 a.m.)
Issued	31 years, 9 months ago (Dec. 1, 1993)
Published	31 years, 9 months ago (Dec. 1, 1993)
Published Online	16 years, 3 months ago (May 15, 2009)
Published Print	31 years, 9 months ago (Dec. 1, 1993)

Funders 0

None

BibTeX

@article{Bode_1993, title={The coccoid forms ofHelicobacter pylori. Criteria for their viability}, volume={111}, ISSN={1469-4409}, url={http://dx.doi.org/10.1017/s0950268800057216}, DOI={10.1017/s0950268800057216}, number={3}, journal={Epidemiology and Infection}, publisher={Cambridge University Press (CUP)}, author={Bode, G. and Mauch, F. and Malfertheiner, P.}, year={1993}, month=dec, pages={483–490} }

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