DOI: 10.1017/s0022172400046507. Interactions of TRIC agents with macrophages and BHK-21 cells observed by electron microscopy

Interactions of TRIC agents with macrophages and BHK-21 cells observed by electron microscopy

10.1017/s0022172400046507

Crossref journal-article

Cambridge University Press (CUP)

Journal of Hygiene (56)

Abstract

SUMMARYTRIC agents do not multiply in mouse peritoneal macrophages in culture but have a toxic effect on them, whereas they multiply readily in BHK-21 cells. Sections of macrophages and of BHK-21 cells fixed during the first 90 min after inoculation were examined by electron microscopy. Macrophages ingested all forms of the organism, which were eventually degraded in lysosomes. However, elementary bodies were distinguished from other TRIC particles by the delay in their transfer to lysosomes. BHK-21 cells ingested elementary bodies selectively, and in these cells the organisms were neither found in lysosomes nor degraded. Instead they showed morphological changes that probably represented an early stage of development.

Bibliography

Lawn, A. M., Blyth, W. A., & Taverne, J. (1973). Interactions of TRIC agents with macrophages and BHK-21 cells observed by electron microscopy. Journal of Hygiene, 71(3), 515â528.

Authors 3

A. M. Lawn (first)
W. A. Blyth (additional)
Janice Taverne (additional)

References 15 Referenced 41

Tamura A. (1971). Observations on early changes in Chlamydia psittaci following infection of L cells. Bacteriological Proceedings, p. 90.
10.1038/195923a0
10.1128/JB.110.2.706-721.1972 / Journal of Bacteriology / Interaction of L cells and Chlamydia psittaci: entry of the parasite and host responses to its development by Friis (1972)
10.1083/jcb.38.3.615
10.1038/221658a0
10.1084/jem.136.5.1173
{'key': 'S0022172400046507_ref006', 'first-page': '278', 'article-title': 'Electron microscopic study of phagocytosis of Histoplasma capsulatum by hamster peritoneal macrophages', 'volume': '23', 'author': 'Dumont', 'year': '1970', 'journal-title': 'Laboratory Investigation'} / Laboratory Investigation / Electron microscopic study of phagocytosis of Histoplasma capsulatum by hamster peritoneal macrophages by Dumont (1970)
10.1002/path.1711020105
{'key': 'S0022172400046507_ref014', 'first-page': '88', 'volume-title': 'Trachoma and Related Disorders', 'author': 'Taverne', 'year': '1971'} / Trachoma and Related Disorders by Taverne (1971)
10.1099/00221287-37-2-271
10.1084/jem.134.3.713
10.1083/jcb.50.3.859
10.1016/S0022-5320(72)90088-3
10.1083/jcb.25.2.407
10.1128/JB.90.5.1387-1404.1965 / Journal of Bacteriology / Comparison of the ultrastructure of several Rickettsiae, ornithosis virus and Mycoplasma in tissue culture by Anderson (1965)

Dates

Type	When
Created	16 years, 3 months ago (May 15, 2009, 6:06 a.m.)
Deposited	5 years, 3 months ago (May 18, 2020, 1:13 a.m.)
Indexed	1 year, 10 months ago (Oct. 29, 2023, 8:19 a.m.)
Issued	52 years ago (Sept. 1, 1973)
Published	52 years ago (Sept. 1, 1973)
Published Online	16 years, 3 months ago (May 15, 2009)
Published Print	52 years ago (Sept. 1, 1973)

Funders 0

None

BibTeX

@article{Lawn_1973, title={Interactions of TRIC agents with macrophages and BHK-21 cells observed by electron microscopy}, volume={71}, ISSN={0022-1724}, url={http://dx.doi.org/10.1017/s0022172400046507}, DOI={10.1017/s0022172400046507}, number={3}, journal={Journal of Hygiene}, publisher={Cambridge University Press (CUP)}, author={Lawn, A. M. and Blyth, W. A. and Taverne, Janice}, year={1973}, month=sep, pages={515–528} }

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