DOI: 10.1016/j.ymthe.2005.03.038. Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes

Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes

10.1016/j.ymthe.2005.03.038

Crossref journal-article

Elsevier BV

Molecular Therapy (78)

Bibliography

Rejman, J., Bragonzi, A., & Conese, M. (2005). Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes. Molecular Therapy, 12(3), 468â474.

Authors 3

Joanna Rejman (first)
Alessandra Bragonzi (additional)
Massimo Conese (additional)

References 40 Referenced 730

{'key': '10.1016/j.ymthe.2005.03.038_bib1', 'first-page': '710', 'article-title': 'Cationic liposome-mediated gene transfer', 'volume': '2', 'author': 'Gao', 'year': '1995', 'journal-title': 'Gene Ther.'} / Gene Ther. / Cationic liposome-mediated gene transfer by Gao (1995)
10.1038/sj.gt.3301110 / Gene Ther. / Nonviral gene therapy: promises and challenges by Li (2000)
10.1038/sj.gt.3300717 / Gene Ther. / Polyethylenimine-based intravenous delivery of transgenes to mouse lung by Goula (1998)
10.1038/sj.gt.3300503 / Gene Ther. / ExGen 500 is an efficient vector for gene delivery to lung epithelial cells in vitro and in vivo by Ferrari (1997)
10.1038/sj.gt.3301039 / Gene Ther. / Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs by Bragonzi (1999)
10.1016/0005-2736(95)00219-7 / Biochim. Biophys. Acta / Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes by Friend (1996)
10.1074/jbc.M111257200 / J. Biol. Chem. / Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis by Zuhorn (2002)
{'key': '10.1016/j.ymthe.2005.03.038_bib8', 'first-page': '1010', 'article-title': 'An electron microscopy study into the mechanism of gene transfer with lipopolyamines', 'volume': '3', 'author': 'Labat-Moleur', 'year': '1996', 'journal-title': 'Gene Ther.'} / Gene Ther. / An electron microscopy study into the mechanism of gene transfer with lipopolyamines by Labat-Moleur (1996)
10.1074/jbc.272.2.1117 / J. Biol. Chem. / Loss of binding and entry of liposome–DNA complexes decreases transfection efficiency in differentiated airway epithelial cells by Matsui (1997)
10.1016/0005-2736(95)80016-9 / Biochim. Biophys. Acta / The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer by Farhood (1995)
10.1126/science.281.5373.78 / Science / An inverted hexagonal phase of cationic liposome–DNA complexes related to DNA release and delivery by Koltover (1998)
10.1074/jbc.M106199200 / J. Biol. Chem. / Molecular shape of the cationic lipid controls the structure of cationic lipid/dioleylphosphatidylethanolamine–DNA complexes and the efficiency of gene delivery by Smisterova (2001)
10.1021/bi9602019 / Biochemistry / Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection by Xu (1996)
10.1021/bc00023a012 / Bioconjugate Chem. / Polyamidoamine cascade polymers mediate efficient transfection of cells in culture by Haensler (1993)
10.1073/pnas.92.16.7297 / Proc. Natl. Acad. Sci. USA / A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine by Boussif (1995)
10.2533/chimia.1997.34 / Chimia / The proton sponge: a trick to enter cells the viruses did not exploit by Behr (1997)
10.1038/sj.gt.3301282 / Gene Ther. / Biodistribution and transgene expression with nonviral cationic vector/DNA complexes in the lungs by Bragonzi (2000)
10.1002/jgm.173 / J. Gene Med. / Polyethylenimine-mediated gene delivery: a mechanistic study by Kichler (2001)
10.1242/jcs.113.19.3509 / J. Cell Sci. / Isoforms of caveolin-1 and caveolar structure by Fujimoto (2000)
10.1208/ps030321 / AAPS PharmSci. / DNA/polyethylenimine transfection particles: influence of ligands, polymer size, and PEGylation on internalization and gene expression by Ogris (2001)
10.1042/bj20031253 / Biochem. J. / Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis by Rejman (2004)
10.1002/(SICI)1521-2254(200003/04)2:2<128::AID-JGM95>3.0.CO;2-W / J. Gene Med. / Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse by Zou (2000)
10.1038/sj.gt.3301113 / Gene Ther. / Rapid crossing of the pulmonary endothelial barrier by polyethylenimine/DNA complexes by Goula (2000)
10.1002/jgm.187 / J. Gene Med. / Different behaviour of branched and linear polyethylenimine for gene delivery in vitro and in vivo by Wightman (2001)
10.1016/S0006-2952(98)00098-7 / Biochem. Pharmacol. / Effects of polyethyleneimine on endocytosis and lysosome stability by Klemm (1998)
10.1006/bbrc.2000.3809 / Biochem. Biophys. Res. Commun. / Uptake and intracellular fate of polyethylenimine in vivo by Lecocq (2000)
10.1002/1097-4636(20000905)51:3<321::AID-JBM5>3.0.CO;2-R / J. Biomed. Mater. Res. / Poly(ethylenimine)-mediated transfection: a new paradigm for gene delivery by Godbey (2000)
10.1016/S0168-3659(02)00129-3 / J. Controlled Release / Intracellular route and transcriptional competence of polyethylenimine–DNA complexes by Bieber (2002)
10.1016/S1286-4579(01)01423-X / Microbes Infect. / Caveolae as portals of entry for microbes by Shin (2001)
10.1126/science.2200126 / Science / Toxoplasma gondii: fusion competence of parasitophorous vacuoles in Fc receptor-transfected fibroblasts by Joiner (1990)
10.1038/sj.gt.3301506 / Gene Ther. / On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids by Hafez (2001)
10.1006/mthe.2002.0631 / Mol. Ther. / On the kinetics of polyplex endocytic trafficking: implications for gene delivery vector design by Forrest (2002)
10.1016/0092-8674(83)90356-2 / Cell / Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts by Larkin (1983)
10.1083/jcb.123.5.1107 / J. Cell Biol. / Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation by Wang (1993)
10.1006/excr.1999.4652 / Exp. Cell Res. / Tyrosine phosphorylation of caveolin-1 in the endothelium by Aoki (1999)
10.1006/bbrc.1999.1082 / Biochem. Biophys. Res. Commun. / Spatial organization of EGF receptor transmodulation by PDGF by Liu (1999)
10.1083/jcb.127.5.1217 / J. Cell Biol. / Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules by Schnitzer (1994)
10.1083/jcb.141.4.905 / J. Cell Biol. / Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains by Orlandi (1998)
10.1083/jcb.200102084 / J. Cell Biol. / Clathrin-dependent and -independent internalization of plasma membrane sphingolipids initiates two Golgi targeting pathways by Puri (2001)
10.1089/10430349950017284 / Hum. Gene Ther. / Restoration of bacterial killing activity of human respiratory cystic fibrosis cells through cationic vector-mediated CFTR gene transfer by Biffi (1999)

Dates

Type	When
Created	20 years, 2 months ago (June 20, 2005, 4:04 p.m.)
Deposited	2 years, 4 months ago (May 3, 2023, 9:07 a.m.)
Indexed	1 week, 5 days ago (Aug. 23, 2025, 1:01 a.m.)
Issued	20 years ago (Sept. 1, 2005)
Published	20 years ago (Sept. 1, 2005)
Published Print	20 years ago (Sept. 1, 2005)

Funders 0

None

BibTeX

@article{Rejman_2005, title={Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes}, volume={12}, ISSN={1525-0016}, url={http://dx.doi.org/10.1016/j.ymthe.2005.03.038}, DOI={10.1016/j.ymthe.2005.03.038}, number={3}, journal={Molecular Therapy}, publisher={Elsevier BV}, author={Rejman, Joanna and Bragonzi, Alessandra and Conese, Massimo}, year={2005}, month=sep, pages={468–474} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        23
      ]
    ],
    "date-time": "2025-08-23T05:01:40Z",
    "timestamp": 1755925300032
  },
  "reference-count": 40,
  "publisher": "Elsevier BV",
  "issue": "3",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2005,
            9,
            1
          ]
        ],
        "date-time": "2005-09-01T00:00:00Z",
        "timestamp": 1125532800000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    },
    {
      "start": {
        "date-parts": [
          [
            2016,
            10,
            7
          ]
        ],
        "date-time": "2016-10-07T00:00:00Z",
        "timestamp": 1475798400000
      },
      "content-version": "vor",
      "delay-in-days": 4054,
      "URL": "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2005,
        9
      ]
    ]
  },
  "DOI": "10.1016/j.ymthe.2005.03.038",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2005,
        6,
        20
      ]
    ],
    "date-time": "2005-06-20T20:04:24Z",
    "timestamp": 1119297864000
  },
  "page": "468-474",
  "source": "Crossref",
  "is-referenced-by-count": 730,
  "title": "Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes",
  "prefix": "10.1016",
  "volume": "12",
  "author": [
    {
      "given": "Joanna",
      "family": "Rejman",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Alessandra",
      "family": "Bragonzi",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Massimo",
      "family": "Conese",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib1",
      "first-page": "710",
      "article-title": "Cationic liposome-mediated gene transfer",
      "volume": "2",
      "author": "Gao",
      "year": "1995",
      "journal-title": "Gene Ther."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib2",
      "doi-asserted-by": "crossref",
      "first-page": "31",
      "DOI": "10.1038/sj.gt.3301110",
      "article-title": "Nonviral gene therapy: promises and challenges",
      "volume": "7",
      "author": "Li",
      "year": "2000",
      "journal-title": "Gene Ther."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib3",
      "doi-asserted-by": "crossref",
      "first-page": "1291",
      "DOI": "10.1038/sj.gt.3300717",
      "article-title": "Polyethylenimine-based intravenous delivery of transgenes to mouse lung",
      "volume": "5",
      "author": "Goula",
      "year": "1998",
      "journal-title": "Gene Ther."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib4",
      "doi-asserted-by": "crossref",
      "first-page": "1100",
      "DOI": "10.1038/sj.gt.3300503",
      "article-title": "ExGen 500 is an efficient vector for gene delivery to lung epithelial cells in vitro and in vivo",
      "volume": "4",
      "author": "Ferrari",
      "year": "1997",
      "journal-title": "Gene Ther."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib5",
      "doi-asserted-by": "crossref",
      "first-page": "1995",
      "DOI": "10.1038/sj.gt.3301039",
      "article-title": "Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs",
      "volume": "6",
      "author": "Bragonzi",
      "year": "1999",
      "journal-title": "Gene Ther."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib6",
      "doi-asserted-by": "crossref",
      "first-page": "41",
      "DOI": "10.1016/0005-2736(95)00219-7",
      "article-title": "Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes",
      "volume": "1278",
      "author": "Friend",
      "year": "1996",
      "journal-title": "Biochim. Biophys. Acta"
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "18021",
      "DOI": "10.1074/jbc.M111257200",
      "article-title": "Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis",
      "volume": "277",
      "author": "Zuhorn",
      "year": "2002",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib8",
      "first-page": "1010",
      "article-title": "An electron microscopy study into the mechanism of gene transfer with lipopolyamines",
      "volume": "3",
      "author": "Labat-Moleur",
      "year": "1996",
      "journal-title": "Gene Ther."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "1117",
      "DOI": "10.1074/jbc.272.2.1117",
      "article-title": "Loss of binding and entry of liposome\u2013DNA complexes decreases transfection efficiency in differentiated airway epithelial cells",
      "volume": "272",
      "author": "Matsui",
      "year": "1997",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "289",
      "DOI": "10.1016/0005-2736(95)80016-9",
      "article-title": "The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer",
      "volume": "1235",
      "author": "Farhood",
      "year": "1995",
      "journal-title": "Biochim. Biophys. Acta"
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib11",
      "doi-asserted-by": "crossref",
      "first-page": "78",
      "DOI": "10.1126/science.281.5373.78",
      "article-title": "An inverted hexagonal phase of cationic liposome\u2013DNA complexes related to DNA release and delivery",
      "volume": "281",
      "author": "Koltover",
      "year": "1998",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "47615",
      "DOI": "10.1074/jbc.M106199200",
      "article-title": "Molecular shape of the cationic lipid controls the structure of cationic lipid/dioleylphosphatidylethanolamine\u2013DNA complexes and the efficiency of gene delivery",
      "volume": "276",
      "author": "Smisterova",
      "year": "2001",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "5616",
      "DOI": "10.1021/bi9602019",
      "article-title": "Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection",
      "volume": "35",
      "author": "Xu",
      "year": "1996",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib14",
      "doi-asserted-by": "crossref",
      "first-page": "372",
      "DOI": "10.1021/bc00023a012",
      "article-title": "Polyamidoamine cascade polymers mediate efficient transfection of cells in culture",
      "volume": "4",
      "author": "Haensler",
      "year": "1993",
      "journal-title": "Bioconjugate Chem."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "7297",
      "DOI": "10.1073/pnas.92.16.7297",
      "article-title": "A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine",
      "volume": "92",
      "author": "Boussif",
      "year": "1995",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib16",
      "doi-asserted-by": "crossref",
      "first-page": "34",
      "DOI": "10.2533/chimia.1997.34",
      "article-title": "The proton sponge: a trick to enter cells the viruses did not exploit",
      "volume": "51",
      "author": "Behr",
      "year": "1997",
      "journal-title": "Chimia"
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib17",
      "doi-asserted-by": "crossref",
      "first-page": "1753",
      "DOI": "10.1038/sj.gt.3301282",
      "article-title": "Biodistribution and transgene expression with nonviral cationic vector/DNA complexes in the lungs",
      "volume": "7",
      "author": "Bragonzi",
      "year": "2000",
      "journal-title": "Gene Ther."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "135",
      "DOI": "10.1002/jgm.173",
      "article-title": "Polyethylenimine-mediated gene delivery: a mechanistic study",
      "volume": "3",
      "author": "Kichler",
      "year": "2001",
      "journal-title": "J. Gene Med."
    },
    {
      "issue": "Pt 19",
      "key": "10.1016/j.ymthe.2005.03.038_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "3509",
      "DOI": "10.1242/jcs.113.19.3509",
      "article-title": "Isoforms of caveolin-1 and caveolar structure",
      "volume": "113",
      "author": "Fujimoto",
      "year": "2000",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "E21",
      "DOI": "10.1208/ps030321",
      "article-title": "DNA/polyethylenimine transfection particles: influence of ligands, polymer size, and PEGylation on internalization and gene expression",
      "volume": "3",
      "author": "Ogris",
      "year": "2001",
      "journal-title": "AAPS PharmSci."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "159",
      "DOI": "10.1042/bj20031253",
      "article-title": "Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis",
      "volume": "377",
      "author": "Rejman",
      "year": "2004",
      "journal-title": "Biochem. J."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "128",
      "DOI": "10.1002/(SICI)1521-2254(200003/04)2:2<128::AID-JGM95>3.0.CO;2-W",
      "article-title": "Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse",
      "volume": "2",
      "author": "Zou",
      "year": "2000",
      "journal-title": "J. Gene Med."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "499",
      "DOI": "10.1038/sj.gt.3301113",
      "article-title": "Rapid crossing of the pulmonary endothelial barrier by polyethylenimine/DNA complexes",
      "volume": "7",
      "author": "Goula",
      "year": "2000",
      "journal-title": "Gene Ther."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "362",
      "DOI": "10.1002/jgm.187",
      "article-title": "Different behaviour of branched and linear polyethylenimine for gene delivery in vitro and in vivo",
      "volume": "3",
      "author": "Wightman",
      "year": "2001",
      "journal-title": "J. Gene Med."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "41",
      "DOI": "10.1016/S0006-2952(98)00098-7",
      "article-title": "Effects of polyethyleneimine on endocytosis and lysosome stability",
      "volume": "56",
      "author": "Klemm",
      "year": "1998",
      "journal-title": "Biochem. Pharmacol."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "414",
      "DOI": "10.1006/bbrc.2000.3809",
      "article-title": "Uptake and intracellular fate of polyethylenimine in vivo",
      "volume": "278",
      "author": "Lecocq",
      "year": "2000",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "321",
      "DOI": "10.1002/1097-4636(20000905)51:3<321::AID-JBM5>3.0.CO;2-R",
      "article-title": "Poly(ethylenimine)-mediated transfection: a new paradigm for gene delivery",
      "volume": "51",
      "author": "Godbey",
      "year": "2000",
      "journal-title": "J. Biomed. Mater. Res."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "441",
      "DOI": "10.1016/S0168-3659(02)00129-3",
      "article-title": "Intracellular route and transcriptional competence of polyethylenimine\u2013DNA complexes",
      "volume": "82",
      "author": "Bieber",
      "year": "2002",
      "journal-title": "J. Controlled Release"
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "755",
      "DOI": "10.1016/S1286-4579(01)01423-X",
      "article-title": "Caveolae as portals of entry for microbes",
      "volume": "3",
      "author": "Shin",
      "year": "2001",
      "journal-title": "Microbes Infect."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "641",
      "DOI": "10.1126/science.2200126",
      "article-title": "Toxoplasma gondii: fusion competence of parasitophorous vacuoles in Fc receptor-transfected fibroblasts",
      "volume": "249",
      "author": "Joiner",
      "year": "1990",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "1188",
      "DOI": "10.1038/sj.gt.3301506",
      "article-title": "On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids",
      "volume": "8",
      "author": "Hafez",
      "year": "2001",
      "journal-title": "Gene Ther."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "57",
      "DOI": "10.1006/mthe.2002.0631",
      "article-title": "On the kinetics of polyplex endocytic trafficking: implications for gene delivery vector design",
      "volume": "6",
      "author": "Forrest",
      "year": "2002",
      "journal-title": "Mol. Ther."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "273",
      "DOI": "10.1016/0092-8674(83)90356-2",
      "article-title": "Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts",
      "volume": "33",
      "author": "Larkin",
      "year": "1983",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "1107",
      "DOI": "10.1083/jcb.123.5.1107",
      "article-title": "Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation",
      "volume": "123",
      "author": "Wang",
      "year": "1993",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "629",
      "DOI": "10.1006/excr.1999.4652",
      "article-title": "Tyrosine phosphorylation of caveolin-1 in the endothelium",
      "volume": "253",
      "author": "Aoki",
      "year": "1999",
      "journal-title": "Exp. Cell Res."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "695",
      "DOI": "10.1006/bbrc.1999.1082",
      "article-title": "Spatial organization of EGF receptor transmodulation by PDGF",
      "volume": "261",
      "author": "Liu",
      "year": "1999",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib37",
      "doi-asserted-by": "crossref",
      "first-page": "1217",
      "DOI": "10.1083/jcb.127.5.1217",
      "article-title": "Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules",
      "volume": "127",
      "author": "Schnitzer",
      "year": "1994",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib38",
      "doi-asserted-by": "crossref",
      "first-page": "905",
      "DOI": "10.1083/jcb.141.4.905",
      "article-title": "Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains",
      "volume": "141",
      "author": "Orlandi",
      "year": "1998",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib39",
      "doi-asserted-by": "crossref",
      "first-page": "535",
      "DOI": "10.1083/jcb.200102084",
      "article-title": "Clathrin-dependent and -independent internalization of plasma membrane sphingolipids initiates two Golgi targeting pathways",
      "volume": "154",
      "author": "Puri",
      "year": "2001",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/j.ymthe.2005.03.038_bib40",
      "doi-asserted-by": "crossref",
      "first-page": "1923",
      "DOI": "10.1089/10430349950017284",
      "article-title": "Restoration of bacterial killing activity of human respiratory cystic fibrosis cells through cationic vector-mediated CFTR gene transfer",
      "volume": "10",
      "author": "Biffi",
      "year": "1999",
      "journal-title": "Hum. Gene Ther."
    }
  ],
  "container-title": "Molecular Therapy",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S1525001605001875?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S1525001605001875?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        5,
        3
      ]
    ],
    "date-time": "2023-05-03T13:07:55Z",
    "timestamp": 1683119275000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S1525001605001875"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2005,
        9
      ]
    ]
  },
  "references-count": 40,
  "journal-issue": {
    "issue": "3",
    "published-print": {
      "date-parts": [
        [
          2005,
          9
        ]
      ]
    }
  },
  "alternative-id": [
    "S1525001605001875"
  ],
  "URL": "http://dx.doi.org/10.1016/j.ymthe.2005.03.038",
  "relation": {},
  "ISSN": [
    "1525-0016"
  ],
  "subject": [],
  "container-title-short": "Molecular Therapy",
  "published": {
    "date-parts": [
      [
        2005,
        9
      ]
    ]
  }
}