DOI: 10.1016/j.tins.2004.05.013. Milestones of neuronal development in the adult hippocampus

Milestones of neuronal development in the adult hippocampus

10.1016/j.tins.2004.05.013

Crossref journal-article

Elsevier BV

Trends in Neurosciences (78)

Bibliography

Kempermann, G., Jessberger, S., Steiner, B., & Kronenberg, G. (2004). Milestones of neuronal development in the adult hippocampus. Trends in Neurosciences, 27(8), 447â452.

Authors 4

Gerd Kempermann (first)
Sebastian Jessberger (additional)
Barbara Steiner (additional)
Golo Kronenberg (additional)

References 50 Referenced 1,144

10.1523/JNEUROSCI.12-09-03642.1992 / J. Neurosci. / Adrenal hormones suppress cell division in the adult rat dentate gyrus by Gould (1992)
10.1038/6368 / Nat. Neurosci. / Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus by Van Praag (1999)
10.1038/6365 / Nat. Neurosci. / Learning enhances adult neurogenesis in the hippocampal formation by Gould (1999)
10.1038/386493a0 / Nature / More hippocampal neurons in adult mice living in an enriched environment by Kempermann (1997)
10.1523/JNEUROSCI.18-19-07768.1998 / J. Neurosci. / Increased neurogenesis in the dentate gyrus after transient ischemia in gerbils by Liu (1998)
10.1016/S0306-4522(97)00127-9 / Neuroscience / Lesion-induced proliferation of neuronal progenitor cells in the dentate gyrus of the adult rat by Gould (1997)
10.1073/pnas.94.19.10432 / Proc. Natl. Acad. Sci. U. S. A. / Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures by Bengzon (1997)
10.1523/JNEUROSCI.17-10-03727.1997 / J. Neurosci. / Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus by Parent (1997)
10.1016/S0079-6123(02)35012-X / Prog. Brain Res. / Seizure-induced neurogenesis: are more new neurons good for an adult brain? by Parent (2002)
10.1038/sj.mp.4000712 / Mol. Psychiatry / Adult brain neurogenesis and psychiatry: a novel theory of depression by Jacobs (2000)
D'Sa, C. and Duman, R.S. (2002) Antidepressants and neuroplasticity. Bipolar Disord. 4, 183–194. (10.1034/j.1399-5618.2002.01203.x)
10.1016/S0006-3223(03)00319-6 / Biol. Psychiatry / Depressed new neurons? – Adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression by Kempermann (2003)
10.1016/S0165-3806(01)00243-7 / Brain Res. Dev. Brain Res. / Is it all DNA repair? Methodological considerations for detecting neurogenesis in the adult brain by Cooper-Kuhn (2002)
10.1016/S0165-3806(01)00324-8 / Brain Res. Dev. Brain Res. / Dynamics of cell proliferation in the adult dentate gyrus of two inbred strains of mice by Hayes (2002)
10.1523/JNEUROSCI.16-06-02027.1996 / J. Neurosci. / Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation by Kuhn (1996)
10.1242/dev.00203 / Development / Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice by Kempermann (2003)
10.1007/BF00250261 / Exp. Brain Res. / Evidence that granule cells generated in the dentate gyrus of adult rats extend axonal projections by Stanfield (1988)
10.1111/j.1460-9568.2003.02986.x / Eur. J. Neurosci. / Adult-born hippocampal neurons mature into activity-dependent responsiveness by Jessberger (2003)
10.1523/JNEUROSCI.21-18-07153.2001 / J. Neurosci. / Astrocytes give rise to new neurons in the adult mammalian hippocampus by Seri (2001)
10.1016/S1044-7431(03)00060-5 / Mol. Cell. Neurosci. / Subpopulation of nestin-expressing progenitor cells in the adult murine hippocampus shows electrophysiological and morphological characteristics of astrocytes by Filippov (2003)
10.1002/glia.10337 / Glia / Differential regulation of gliogenesis in the context of adult hippocampal neurogenesis in mice by Steiner (2004)
10.1016/S0304-3940(00)01368-9 / Neurosci. Lett. / Analysis of neurogenesis and programmed cell death reveals a self-renewing capacity in the adult rat brain by Biebl (2000)
10.1038/7449 / Nat. Med. / Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective by Young (1999)
10.1523/JNEUROSCI.23-28-09357.2003 / J. Neurosci. / Two distinct subpopulations of nestin-positive cells in adult mouse dentate gyrus by Fukuda (2003)
10.1002/cne.10945 / J. Comp. Neurol. / Subpopulations of proliferating cells of the adult hippocampus respond differently to physiologic neurogenic stimuli by Kronenberg (2003)
10.1242/dev.127.24.5253 / Development / Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage by Malatesta (2000)
10.1038/35055553 / Nature / Neurons derived from radial glial cells establish radial units in neocortex by Noctor (2001)
10.1523/JNEUROSCI.22-08-03161.2002 / J. Neurosci. / Dividing precursor cells of the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia by Noctor (2002)
10.1002/glia.10250 / Glia / Radial glia diversity: a matter of cell fate by Kriegstein (2003)
10.1073/pnas.202035899 / Proc. Natl. Acad. Sci. U. S. A. / Reelin, Disabled 1, and β1 integrins are required for the formation of the radial glial scaffold in the hippocampus by Forster (2002)
10.1523/JNEUROSCI.17-13-05046.1997 / J. Neurosci. / Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain by Doetsch (1997)
10.1016/S0092-8674(00)80783-7 / Cell / Subventricular zone astrocytes are neural stem cells in the adult mammalian brain by Doetsch (1999)
10.1038/35067582 / Nat. Rev. Neurosci. / A unified hypothesis on the lineage of neural stem cells by Alvarez-Buylla (2001)
10.1523/JNEUROSCI.22-07-02679.2002 / J. Neurosci. / Enriched odor exposure increases the number of newborn neurons in the adult olfactory bulb and improves odor memory by Rochefort (2002)
10.1046/j.1460-9568.2003.02647.x / Eur. J. Neurosci. / Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis by Brown (2003)
10.1523/JNEUROSCI.22-05-01784.2002 / J. Neurosci. / Adult rodent neurogenic regions: the ventricular subependyma contains neural stem cells, but the dentate gyrus contains restricted progenitors by Seaberg (2002)
10.1006/mcne.1996.0595 / Mol. Cell. Neurosci. / The adult rat hippocampus contains primordial neural stem cells by Palmer (1997)
10.1073/pnas.94.19.10409 / Proc. Natl. Acad. Sci. U. S. A. / Genetic influence on neurogenesis in the dentate gyrus of adult mice by Kempermann (1997)
10.1523/JNEUROSCI.18-09-03206.1998 / J. Neurosci. / Experience-induced neurogenesis in the senescent dentate gyrus by Kempermann (1998)
10.1016/S0306-4522(99)00538-2 / Neuroscience / Microglia and astrocytes in the adult rat brain: comparative immunocytochemical analysis demonstrates the efficacy of lipocortin 1 immunoreactivity by Savchenko (2000)
10.1002/cne.10874 / J. Comp. Neurol. / Transient expression of doublecortin during adult neurogenesis by Brown (2003)
10.1016/S1044-7431(03)00207-0 / Mol. Cell. Neurosci. / Transient calretinin-expression defines early postmitotic step of neuronal differentiation in adult hippocampal neurogenesis of mice by Brandt (2003)
10.1523/JNEUROSCI.13-06-02351.1993 / J. Neurosci. / Highly polysialylated neural cell adhesion molecule (NCAM-H) is expressed by newly generated granule cells in the dentate gyrus of the adult rat by Seki (1993)
10.1002/jnr.10387 / J. Neurosci. Res. / Expression patterns of immature neuronal markers PSA-NCAM, CRMP-4 and NeuroD in the hippocampus of young adult and aged rodents by Seki (2002)
10.1146/annurev.cellbio.17.1.387 / Annu. Rev. Cell Dev. Biol. / Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations by Weissman (2001)
10.1016/S0166-2236(03)00031-6 / Trends Neurosci. / Stem and progenitor cells: the premature desertion of rigorous definitions by Seaberg (2003)
10.1002/(SICI)1096-9861(19991011)413:1<146::AID-CNE10>3.0.CO;2-B / J. Comp. Neurol. / Rapid extension of axons into the CA3 region by adult-generated granule cells by Hastings (1999)
10.1016/S0168-0102(01)00314-5 / Neurosci. Res. / Cell dynamics of calretinin-immunoreactive neurons in the rostral migratory stream after ibotenate-induced lesions in the forebrain by Li (2002)
10.1046/j.1460-9568.1998.00397.x / Eur. J. Neurosci. / Proliferation, migration and differentiation of neuronal progenitor cells in the adult mouse subventricular zone surgically separated from its olfactory bulb by Jankovski (1998)
10.1038/4151030a / Nature / Functional neurogenesis in the adult hippocampus by van Praag (2002)

Dates

Type	When
Created	21 years, 2 months ago (June 15, 2004, 3:32 p.m.)
Deposited	4 years, 2 months ago (June 23, 2021, 5:35 a.m.)
Indexed	2 days, 23 hours ago (Aug. 28, 2025, 8:50 a.m.)
Issued	21 years ago (Aug. 1, 2004)
Published	21 years ago (Aug. 1, 2004)
Published Print	21 years ago (Aug. 1, 2004)

Funders 0

None

BibTeX

@article{Kempermann_2004, title={Milestones of neuronal development in the adult hippocampus}, volume={27}, ISSN={0166-2236}, url={http://dx.doi.org/10.1016/j.tins.2004.05.013}, DOI={10.1016/j.tins.2004.05.013}, number={8}, journal={Trends in Neurosciences}, publisher={Elsevier BV}, author={Kempermann, Gerd and Jessberger, Sebastian and Steiner, Barbara and Kronenberg, Golo}, year={2004}, month=aug, pages={447–452} }

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      "author": "Kempermann",
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      "volume": "18",
      "author": "Liu",
      "year": "1998",
      "journal-title": "J. Neurosci."
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      "article-title": "Lesion-induced proliferation of neuronal progenitor cells in the dentate gyrus of the adult rat",
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      "author": "Bengzon",
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      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
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      "volume": "17",
      "author": "Parent",
      "year": "1997",
      "journal-title": "J. Neurosci."
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      "DOI": "10.1016/S0079-6123(02)35012-X",
      "article-title": "Seizure-induced neurogenesis: are more new neurons good for an adult brain?",
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      "year": "2002",
      "journal-title": "Prog. Brain Res."
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      "volume": "5",
      "author": "Jacobs",
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      "author": "Kempermann",
      "year": "2003",
      "journal-title": "Biol. Psychiatry"
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      "volume": "134",
      "author": "Cooper-Kuhn",
      "year": "2002",
      "journal-title": "Brain Res. Dev. Brain Res."
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      "volume": "134",
      "author": "Hayes",
      "year": "2002",
      "journal-title": "Brain Res. Dev. Brain Res."
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      "volume": "16",
      "author": "Kuhn",
      "year": "1996",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "391",
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      "volume": "130",
      "author": "Kempermann",
      "year": "2003",
      "journal-title": "Development"
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      "volume": "72",
      "author": "Stanfield",
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      "volume": "18",
      "author": "Jessberger",
      "year": "2003",
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      "article-title": "Astrocytes give rise to new neurons in the adult mammalian hippocampus",
      "volume": "21",
      "author": "Seri",
      "year": "2001",
      "journal-title": "J. Neurosci."
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      "author": "Filippov",
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      "journal-title": "Mol. Cell. Neurosci."
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      "volume": "46",
      "author": "Steiner",
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      "journal-title": "Glia"
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      "volume": "291",
      "author": "Biebl",
      "year": "2000",
      "journal-title": "Neurosci. Lett."
    },
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      "first-page": "448",
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      "author": "Young",
      "year": "1999",
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      "volume": "23",
      "author": "Fukuda",
      "year": "2003",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB25",
      "doi-asserted-by": "crossref",
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      "volume": "467",
      "author": "Kronenberg",
      "year": "2003",
      "journal-title": "J. Comp. Neurol."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "5253",
      "DOI": "10.1242/dev.127.24.5253",
      "article-title": "Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage",
      "volume": "127",
      "author": "Malatesta",
      "year": "2000",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "714",
      "DOI": "10.1038/35055553",
      "article-title": "Neurons derived from radial glial cells establish radial units in neocortex",
      "volume": "409",
      "author": "Noctor",
      "year": "2001",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "3161",
      "DOI": "10.1523/JNEUROSCI.22-08-03161.2002",
      "article-title": "Dividing precursor cells of the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia",
      "volume": "22",
      "author": "Noctor",
      "year": "2002",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "37",
      "DOI": "10.1002/glia.10250",
      "article-title": "Radial glia diversity: a matter of cell fate",
      "volume": "43",
      "author": "Kriegstein",
      "year": "2003",
      "journal-title": "Glia"
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "13178",
      "DOI": "10.1073/pnas.202035899",
      "article-title": "Reelin, Disabled 1, and \u03b21 integrins are required for the formation of the radial glial scaffold in the hippocampus",
      "volume": "99",
      "author": "Forster",
      "year": "2002",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "5046",
      "DOI": "10.1523/JNEUROSCI.17-13-05046.1997",
      "article-title": "Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain",
      "volume": "17",
      "author": "Doetsch",
      "year": "1997",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "703",
      "DOI": "10.1016/S0092-8674(00)80783-7",
      "article-title": "Subventricular zone astrocytes are neural stem cells in the adult mammalian brain",
      "volume": "97",
      "author": "Doetsch",
      "year": "1999",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "287",
      "DOI": "10.1038/35067582",
      "article-title": "A unified hypothesis on the lineage of neural stem cells",
      "volume": "2",
      "author": "Alvarez-Buylla",
      "year": "2001",
      "journal-title": "Nat. Rev. Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "2679",
      "DOI": "10.1523/JNEUROSCI.22-07-02679.2002",
      "article-title": "Enriched odor exposure increases the number of newborn neurons in the adult olfactory bulb and improves odor memory",
      "volume": "22",
      "author": "Rochefort",
      "year": "2002",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "2042",
      "DOI": "10.1046/j.1460-9568.2003.02647.x",
      "article-title": "Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis",
      "volume": "17",
      "author": "Brown",
      "year": "2003",
      "journal-title": "Eur. J. Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "1784",
      "DOI": "10.1523/JNEUROSCI.22-05-01784.2002",
      "article-title": "Adult rodent neurogenic regions: the ventricular subependyma contains neural stem cells, but the dentate gyrus contains restricted progenitors",
      "volume": "22",
      "author": "Seaberg",
      "year": "2002",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "389",
      "DOI": "10.1006/mcne.1996.0595",
      "article-title": "The adult rat hippocampus contains primordial neural stem cells",
      "volume": "8",
      "author": "Palmer",
      "year": "1997",
      "journal-title": "Mol. Cell. Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "10409",
      "DOI": "10.1073/pnas.94.19.10409",
      "article-title": "Genetic influence on neurogenesis in the dentate gyrus of adult mice",
      "volume": "94",
      "author": "Kempermann",
      "year": "1997",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "3206",
      "DOI": "10.1523/JNEUROSCI.18-09-03206.1998",
      "article-title": "Experience-induced neurogenesis in the senescent dentate gyrus",
      "volume": "18",
      "author": "Kempermann",
      "year": "1998",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "195",
      "DOI": "10.1016/S0306-4522(99)00538-2",
      "article-title": "Microglia and astrocytes in the adult rat brain: comparative immunocytochemical analysis demonstrates the efficacy of lipocortin 1 immunoreactivity",
      "volume": "96",
      "author": "Savchenko",
      "year": "2000",
      "journal-title": "Neuroscience"
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1002/cne.10874",
      "article-title": "Transient expression of doublecortin during adult neurogenesis",
      "volume": "467",
      "author": "Brown",
      "year": "2003",
      "journal-title": "J. Comp. Neurol."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "603",
      "DOI": "10.1016/S1044-7431(03)00207-0",
      "article-title": "Transient calretinin-expression defines early postmitotic step of neuronal differentiation in adult hippocampal neurogenesis of mice",
      "volume": "24",
      "author": "Brandt",
      "year": "2003",
      "journal-title": "Mol. Cell. Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "2351",
      "DOI": "10.1523/JNEUROSCI.13-06-02351.1993",
      "article-title": "Highly polysialylated neural cell adhesion molecule (NCAM-H) is expressed by newly generated granule cells in the dentate gyrus of the adult rat",
      "volume": "13",
      "author": "Seki",
      "year": "1993",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "327",
      "DOI": "10.1002/jnr.10387",
      "article-title": "Expression patterns of immature neuronal markers PSA-NCAM, CRMP-4 and NeuroD in the hippocampus of young adult and aged rodents",
      "volume": "70",
      "author": "Seki",
      "year": "2002",
      "journal-title": "J. Neurosci. Res."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "387",
      "DOI": "10.1146/annurev.cellbio.17.1.387",
      "article-title": "Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations",
      "volume": "17",
      "author": "Weissman",
      "year": "2001",
      "journal-title": "Annu. Rev. Cell Dev. Biol."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "125",
      "DOI": "10.1016/S0166-2236(03)00031-6",
      "article-title": "Stem and progenitor cells: the premature desertion of rigorous definitions",
      "volume": "26",
      "author": "Seaberg",
      "year": "2003",
      "journal-title": "Trends Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "146",
      "DOI": "10.1002/(SICI)1096-9861(19991011)413:1<146::AID-CNE10>3.0.CO;2-B",
      "article-title": "Rapid extension of axons into the CA3 region by adult-generated granule cells",
      "volume": "413",
      "author": "Hastings",
      "year": "1999",
      "journal-title": "J. Comp. Neurol."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "123",
      "DOI": "10.1016/S0168-0102(01)00314-5",
      "article-title": "Cell dynamics of calretinin-immunoreactive neurons in the rostral migratory stream after ibotenate-induced lesions in the forebrain",
      "volume": "42",
      "author": "Li",
      "year": "2002",
      "journal-title": "Neurosci. Res."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "3853",
      "DOI": "10.1046/j.1460-9568.1998.00397.x",
      "article-title": "Proliferation, migration and differentiation of neuronal progenitor cells in the adult mouse subventricular zone surgically separated from its olfactory bulb",
      "volume": "10",
      "author": "Jankovski",
      "year": "1998",
      "journal-title": "Eur. J. Neurosci."
    },
    {
      "key": "10.1016/j.tins.2004.05.013_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "1030",
      "DOI": "10.1038/4151030a",
      "article-title": "Functional neurogenesis in the adult hippocampus",
      "volume": "415",
      "author": "van Praag",
      "year": "2002",
      "journal-title": "Nature"
    }
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