DOI: 10.1016/j.tibs.2008.04.007. Viral IRES RNA structures and ribosome interactions

Viral IRES RNA structures and ribosome interactions

10.1016/j.tibs.2008.04.007

Crossref journal-article

Elsevier BV

Trends in Biochemical Sciences (78)

Bibliography

Kieft, J. S. (2008). Viral IRES RNA structures and ribosome interactions. Trends in Biochemical Sciences, 33(6), 274â283.

Authors 1

Jeffrey S. Kieft (first)

References 71 Referenced 201

{'key': '10.1016/j.tibs.2008.04.007_bib1', 'series-title': 'Translational Control in Biology and Medicine', 'first-page': '87', 'article-title': 'The mechanism of translation initiation in eukaryotes', 'author': 'Pestova', 'year': '2007'} / Translational Control in Biology and Medicine / The mechanism of translation initiation in eukaryotes by Pestova (2007)
10.1128/JVI.62.8.2636-2643.1988 / J. Virol. / A segment of the 5′ nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation by Jang (1988)
10.1038/334320a0 / Nature / Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA by Pelletier (1988)
{'key': '10.1016/j.tibs.2008.04.007_bib4', 'series-title': 'Translational Control in Biology and Medicine', 'first-page': '129', 'article-title': 'Translation initiation by viral internal ribosome entry sites', 'author': 'Doudna', 'year': '2007'} / Translational Control in Biology and Medicine / Translation initiation by viral internal ribosome entry sites by Doudna (2007)
{'key': '10.1016/j.tibs.2008.04.007_bib5', 'series-title': 'Translational Control in Biology and Medicine', 'first-page': '155', 'article-title': 'Translation initiation via cellular internal ribosome entry sites', 'author': 'Elroy-Stein', 'year': '2007'} / Translational Control in Biology and Medicine / Translation initiation via cellular internal ribosome entry sites by Elroy-Stein (2007)
10.1126/science.7536344 / Science / Initiation of protein synthesis by the eukaryotic translational apparatus on circular RNAs by Chen (1995)
10.1261/rna.157806 / RNA / Searching for IRES by Baird (2006)
10.1016/j.tibs.2007.11.002 / Trends Biochem. Sci. / Was the initiation of translation in early eukaryotes IRES-driven? by Hernandez (2008)
10.1016/0168-1702(92)90143-W / Virus Res. / A cis-acting element within the hepatitis A virus 5′-non-coding region required for in vitro translation by Glass (1992)
10.1128/JVI.66.3.1476-1483.1992 / J. Virol. / Internal ribosome entry site within hepatitis C virus RNA by Tsukiyama-Kohara (1992)
10.1128/JVI.64.10.4625-4631.1990 / J. Virol. / Functional analysis of the internal translation initiation site of foot-and-mouth disease virus by Kuhn (1990)
10.1128/JVI.75.1.181-191.2001 / J. Virol. / The human immunodeficiency virus type 1 gag gene encodes an internal ribosome entry site by Buck (2001)
10.1128/JVI.77.7.3939-3949.2003 / J. Virol. / The leader of human immunodeficiency virus type 1 genomic RNA harbors an internal ribosome entry segment that is active during the G2/M phase of the cell cycle by Brasey (2003)
10.1016/j.virusres.2005.10.011 / Virus Res. / Divergent IRES elements in invertebrates by Jan (2006)
10.1073/pnas.2535183100 / Proc. Natl Acad. Sci. U. S. A. / Divergent tRNA-like element supports initiation, elongation, and termination of protein biosynthesis by Jan (2003)
10.1101/sqb.2001.66.285 / Cold Spring Harb. Symp. Quant. Biol. / Initiator Met-tRNA-independent translation mediated by an internal ribosome entry site element in cricket paralysis virus-like insect viruses by Jan (2001)
10.1016/S0092-8674(00)00055-6 / Cell / Initiation of protein synthesis from the A site of the ribosome by Wilson (2000)
10.1128/MCB.20.14.4990-4999.2000 / Mol. Cell. Biol. / Naturally occurring dicistronic cricket paralysis virus RNA is regulated by two internal ribosome entry sites by Wilson (2000)
10.1073/pnas.010426997 / Proc. Natl Acad. Sci. U. S. A. / Methionine-independent initiation of translation in the capsid protein of an insect RNA virus by Sasaki (2000)
10.1128/JVI.73.2.1219-1226.1999 / J. Virol. / Translation initiation at the CUU codon is mediated by the internal ribosome entry site of an insect picorna-like virus in vitro by Sasaki (1999)
10.1101/gad.1040803 / Genes Dev. / Translation elongation after assembly of ribosomes on the Cricket paralysis virus internal ribosomal entry site without initiation factors or initiator tRNA by Pestova (2003)
10.1017/S1355838201001741 / RNA / A tertiary structure model of the internal ribosome entry site (IRES) for methionine-independent initiation of translation by Kanamori (2001)
10.1016/S0022-2836(02)01099-9 / J. Mol. Biol. / Factorless ribosome assembly on the internal ribosome entry site of cricket paralysis virus by Jan (2002)
10.1093/nar/gkg336 / Nucleic Acids Res. / Structural elements in the internal ribosome entry site of Plautia stali intestine virus responsible for binding with ribosomes by Nishiyama (2003)
10.1261/rna.7184705 / RNA / A preformed compact ribosome-binding domain in the cricket paralysis-like virus IRES RNAs by Costantino (2005)
10.1126/science.1133281 / Science / Structural basis for ribosome recruitment and manipulation by a viral IRES RNA by Pfingsten (2006)
10.1016/j.cell.2004.08.001 / Cell / Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes; the IRES functions as an RNA-based translation factor by Spahn (2004)
10.1038/nsmb1351 / Nat. Struct. Mol. Biol. / tRNA-mRNA mimicry drives translation initiation from a viral IRES by Costantino (2008)
10.1038/nsmb1177 / Nat. Struct. Mol. Biol. / Structure of the ribosome-bound cricket paralysis virus IRES RNA by Schuler (2006)
10.1038/sj.embor.7400240 / EMBO Rep. / Position of the CrPV IRES on the 40S subunit and factor dependence of IRES/80S ribosome assembly by Pestova (2004)
10.1016/j.jmb.2007.04.076 / J. Mol. Biol. / Conservation and diversity among the three-dimensional folds of the Dicistroviridae intergenic region IRESes by Pfingsten (2007)
10.1093/nar/gkl1121 / Nucleic Acids Res. / Eukaryotic ribosomal protein RPS25 interacts with the conserved loop region in a dicistroviral intergenic internal ribosome entry site by Nishiyama (2007)
10.1074/jbc.M610887200 / J. Biol. Chem. / Binding mode of the first aminoacyl-tRNA in translation initiation mediated by Plautia stali intestine virus IRES by Yamamoto (2007)
10.1038/nsmb1060 / Nat. Struct. Mol. Biol. / The hybrid state of tRNA binding is an authentic translation elongation intermediate by Dorner (2006)
10.1074/jbc.M610887200 / J. Biol. Chem. / Binding mode of the first aminoacyl-tRNA in translation initiation mediated by Plautia stali intestine virus internal ribosome entry site by Yamamoto (2007)
10.1126/science.1058409 / Science / Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit by Spahn (2001)
10.1016/S0092-8674(03)00476-8 / Cell / Locking and unlocking of ribosomal motions by Valle (2003)
10.1093/nar/20.19.5041 / Nucleic Acids Res. / Secondary structure of the 5′ nontranslated regions of hepatitis C virus and pestivirus genomic RNAs by Brown (1992)
10.1006/jmbi.1999.3095 / J. Mol. Biol. / The hepatitis C virus internal ribosome entry site adopts an ion-dependent tertiary fold by Kieft (1999)
10.1002/anie.200603807 / Angew. Chem. Int. Ed. Engl. / Functional architecture of HCV IRES domain II stabilized by divalent metal ions in the crystal and in solution by Dibrov (2007)
10.1038/nsb1004 / Nat. Struct. Biol. / Structure of HCV IRES domain II determined by NMR by Lukavsky (2003)
{'key': '10.1016/j.tibs.2008.04.007_bib42', 'first-page': '375', 'article-title': 'A conserved RNA structure within the HCV IRES eIF3-binding site', 'volume': '9', 'author': 'Collier', 'year': '2002', 'journal-title': 'Nat. Struct. Biol.'} / Nat. Struct. Biol. / A conserved RNA structure within the HCV IRES eIF3-binding site by Collier (2002)
{'key': '10.1016/j.tibs.2008.04.007_bib43', 'first-page': '370', 'article-title': 'Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation', 'volume': '9', 'author': 'Kieft', 'year': '2002', 'journal-title': 'Nat. Struct. Biol.'} / Nat. Struct. Biol. / Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation by Kieft (2002)
10.1038/81951 / Nat. Struct. Biol. / Structures of two RNA domains essential for hepatitis C virus internal ribosome entry site function by Lukavsky (2000)
10.1017/S1355838200000935 / RNA / A potential RNA drug target in the hepatitis C virus internal ribosomal entry site by Klinck (2000)
10.1016/j.jmb.2004.08.095 / J. Mol. Biol. / Mutational and structural analysis of stem-loop IIIC of the hepatitis C virus and GB virus B internal ribosome entry sites by Rijnbrand (2004)
10.1038/sj.emboj.7601549 / EMBO J. / HCV and CSFV IRES domain II mediate eIF2 release during 80S ribosome assembly by Locker (2007)
10.1017/S1355838201001790 / RNA / Mechanism of ribosome recruitment by hepatitis C IRES RNA by Kieft (2001)
10.1128/JVI.74.14.6242-6250.2000 / J. Virol. / An enzymatic footprinting analysis of the interaction of 40S ribosomal subunits with the internal ribosomal entry site of hepatitis C virus by Kolupaeva (2000)
10.1016/j.str.2005.08.008 / Structure / Structure of the hepatitis C virus IRES bound to the human 80S ribosome: remodeling of the HCV IRES by Boehringer (2005)
10.1073/pnas.0407402101 / Proc. Natl Acad. Sci. U. S. A. / Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA by Ji (2004)
10.1016/j.cell.2004.09.038 / Cell / The pathway of HCV IRES-mediated translation initiation by Otto (2004)
10.1017/S1355838202022057 / RNA / Ribosomal proteins mediate the hepatitis C virus IRES–HeLa 40S interaction by Otto (2002)
10.1126/science.1118977 / Science / Structural roles for human translation factor eIF3 in initiation of protein synthesis by Siridechadilok (2005)
10.1101/gad.12.1.67 / Genes Dev. / A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs by Pestova (1998)
10.1016/j.molcel.2007.03.018 / Mol. Cell / The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome by Passmore (2007)
10.1038/nrmicro1558 / Nat. Rev. Microbiol. / Structural and mechanistic insights into hepatitis C viral translation initiation by Fraser (2007)
10.1126/science.1131127 / Science / Structure of the 70S ribosome complexed with mRNA and tRNA by Selmer (2006)
10.1261/rna.5208104 / RNA / Structural variant of the intergenic internal ribosome entry site elements in dicistroviruses and computational search for their counterparts by Hatakeyama (2004)
10.1099/0022-1317-83-4-915 / J. Gen. Virol. / Shrimp Taura syndrome virus: genomic characterization and similarity with members of the genus Cricket paralysis-like viruses by Mari (2002)
10.1128/JVI.71.1.451-457.1997 / J. Virol. / Internal entry of ribosomes is directed by the 5′ noncoding region of classical swine fever virus and is dependent on the presence of an RNA pseudoknot upstream of the initiation codon by Rijnbrand (1997)
10.1128/JVI.78.9.4487-4497.2004 / J. Virol. / Functional and structural similarities between the internal ribosome entry sites of hepatitis C virus and porcine teschovirus, a picornavirus by Pisarev (2004)
10.1006/jmbi.1994.1516 / J. Mol. Biol. / Starting window, a distinct element in the cap-independent internal initiation of translation on picornaviral RNA by Pilipenko (1994)
10.1016/0042-6822(92)90523-R / Virology / Initiation of translation of human rhinovirus RNA: mapping the internal ribosome entry site by Borman (1992)
10.1146/annurev.biochem.75.103004.142733 / Annu. Rev. Biochem. / The tmRNA system for translational surveillance and ribosome rescue by Moore (2007)
10.1007/PL00000795 / Cell. Mol. Life Sci. / Novel features in the tRNA-like world of plant viral RNAs by Fechter (2001)
10.2174/1389203023380837 / Curr. Protein Pept. Sci. / Is tRNA binding or tRNA mimicry mandatory for translation factors? by Kristensen (2002)
10.1074/jbc.M304052200 / J. Biol. Chem. / Detection of tRNA-like structure through RNase P cleavage of viral internal ribosome entry site RNAs near the AUG start triplet by Lyons (2003)
10.1093/nar/gki290 / Nucleic Acids Res. / Characterizing the function and structural organization of the 5′ tRNA-like motif within the hepatitis C virus quasispecies by Piron (2005)
10.1261/rna.506607 / RNA / Characterization of a cyanobacterial RNase P ribozyme recognition motif in the IRES of foot-and-mouth disease virus reveals a unique structural element by Serrano (2007)
10.1016/j.biochi.2007.05.009 / Biochimie / RNase P RNA mediated cleavage: substrate recognition and catalysis by Kirsebom (2007)

Dates

Type	When
Created	17 years, 2 months ago (May 29, 2008, 6:42 a.m.)
Deposited	5 years, 3 months ago (May 5, 2020, 8:41 p.m.)
Indexed	2 weeks ago (Aug. 7, 2025, 4:31 p.m.)
Issued	17 years, 2 months ago (June 1, 2008)
Published	17 years, 2 months ago (June 1, 2008)
Published Print	17 years, 2 months ago (June 1, 2008)

Funders 0

None

BibTeX

@article{Kieft_2008, title={Viral IRES RNA structures and ribosome interactions}, volume={33}, ISSN={0968-0004}, url={http://dx.doi.org/10.1016/j.tibs.2008.04.007}, DOI={10.1016/j.tibs.2008.04.007}, number={6}, journal={Trends in Biochemical Sciences}, publisher={Elsevier BV}, author={Kieft, Jeffrey S.}, year={2008}, month=jun, pages={274–283} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        7
      ]
    ],
    "date-time": "2025-08-07T20:31:43Z",
    "timestamp": 1754598703446
  },
  "reference-count": 71,
  "publisher": "Elsevier BV",
  "issue": "6",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2008,
            6,
            1
          ]
        ],
        "date-time": "2008-06-01T00:00:00Z",
        "timestamp": 1212278400000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2008,
        6
      ]
    ]
  },
  "DOI": "10.1016/j.tibs.2008.04.007",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2008,
        5,
        29
      ]
    ],
    "date-time": "2008-05-29T10:42:19Z",
    "timestamp": 1212057739000
  },
  "page": "274-283",
  "source": "Crossref",
  "is-referenced-by-count": 201,
  "title": "Viral IRES RNA structures and ribosome interactions",
  "prefix": "10.1016",
  "volume": "33",
  "author": [
    {
      "given": "Jeffrey S.",
      "family": "Kieft",
      "sequence": "first",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/j.tibs.2008.04.007_bib1",
      "series-title": "Translational Control in Biology and Medicine",
      "first-page": "87",
      "article-title": "The mechanism of translation initiation in eukaryotes",
      "author": "Pestova",
      "year": "2007"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib2",
      "doi-asserted-by": "crossref",
      "first-page": "2636",
      "DOI": "10.1128/JVI.62.8.2636-2643.1988",
      "article-title": "A segment of the 5\u2032 nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation",
      "volume": "62",
      "author": "Jang",
      "year": "1988",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib3",
      "doi-asserted-by": "crossref",
      "first-page": "320",
      "DOI": "10.1038/334320a0",
      "article-title": "Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA",
      "volume": "334",
      "author": "Pelletier",
      "year": "1988",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib4",
      "series-title": "Translational Control in Biology and Medicine",
      "first-page": "129",
      "article-title": "Translation initiation by viral internal ribosome entry sites",
      "author": "Doudna",
      "year": "2007"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib5",
      "series-title": "Translational Control in Biology and Medicine",
      "first-page": "155",
      "article-title": "Translation initiation via cellular internal ribosome entry sites",
      "author": "Elroy-Stein",
      "year": "2007"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib6",
      "doi-asserted-by": "crossref",
      "first-page": "415",
      "DOI": "10.1126/science.7536344",
      "article-title": "Initiation of protein synthesis by the eukaryotic translational apparatus on circular RNAs",
      "volume": "268",
      "author": "Chen",
      "year": "1995",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "1755",
      "DOI": "10.1261/rna.157806",
      "article-title": "Searching for IRES",
      "volume": "12",
      "author": "Baird",
      "year": "2006",
      "journal-title": "RNA"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib8",
      "doi-asserted-by": "crossref",
      "first-page": "58",
      "DOI": "10.1016/j.tibs.2007.11.002",
      "article-title": "Was the initiation of translation in early eukaryotes IRES-driven?",
      "volume": "33",
      "author": "Hernandez",
      "year": "2008",
      "journal-title": "Trends Biochem. Sci."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "15",
      "DOI": "10.1016/0168-1702(92)90143-W",
      "article-title": "A cis-acting element within the hepatitis A virus 5\u2032-non-coding region required for in vitro translation",
      "volume": "26",
      "author": "Glass",
      "year": "1992",
      "journal-title": "Virus Res."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "1476",
      "DOI": "10.1128/JVI.66.3.1476-1483.1992",
      "article-title": "Internal ribosome entry site within hepatitis C virus RNA",
      "volume": "66",
      "author": "Tsukiyama-Kohara",
      "year": "1992",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib11",
      "doi-asserted-by": "crossref",
      "first-page": "4625",
      "DOI": "10.1128/JVI.64.10.4625-4631.1990",
      "article-title": "Functional analysis of the internal translation initiation site of foot-and-mouth disease virus",
      "volume": "64",
      "author": "Kuhn",
      "year": "1990",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "181",
      "DOI": "10.1128/JVI.75.1.181-191.2001",
      "article-title": "The human immunodeficiency virus type 1 gag gene encodes an internal ribosome entry site",
      "volume": "75",
      "author": "Buck",
      "year": "2001",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "3939",
      "DOI": "10.1128/JVI.77.7.3939-3949.2003",
      "article-title": "The leader of human immunodeficiency virus type 1 genomic RNA harbors an internal ribosome entry segment that is active during the G2/M phase of the cell cycle",
      "volume": "77",
      "author": "Brasey",
      "year": "2003",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib14",
      "doi-asserted-by": "crossref",
      "first-page": "16",
      "DOI": "10.1016/j.virusres.2005.10.011",
      "article-title": "Divergent IRES elements in invertebrates",
      "volume": "119",
      "author": "Jan",
      "year": "2006",
      "journal-title": "Virus Res."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "15410",
      "DOI": "10.1073/pnas.2535183100",
      "article-title": "Divergent tRNA-like element supports initiation, elongation, and termination of protein biosynthesis",
      "volume": "100",
      "author": "Jan",
      "year": "2003",
      "journal-title": "Proc. Natl Acad. Sci. U. S. A."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib16",
      "doi-asserted-by": "crossref",
      "first-page": "285",
      "DOI": "10.1101/sqb.2001.66.285",
      "article-title": "Initiator Met-tRNA-independent translation mediated by an internal ribosome entry site element in cricket paralysis virus-like insect viruses",
      "volume": "66",
      "author": "Jan",
      "year": "2001",
      "journal-title": "Cold Spring Harb. Symp. Quant. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib17",
      "doi-asserted-by": "crossref",
      "first-page": "511",
      "DOI": "10.1016/S0092-8674(00)00055-6",
      "article-title": "Initiation of protein synthesis from the A site of the ribosome",
      "volume": "102",
      "author": "Wilson",
      "year": "2000",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "4990",
      "DOI": "10.1128/MCB.20.14.4990-4999.2000",
      "article-title": "Naturally occurring dicistronic cricket paralysis virus RNA is regulated by two internal ribosome entry sites",
      "volume": "20",
      "author": "Wilson",
      "year": "2000",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "1512",
      "DOI": "10.1073/pnas.010426997",
      "article-title": "Methionine-independent initiation of translation in the capsid protein of an insect RNA virus",
      "volume": "97",
      "author": "Sasaki",
      "year": "2000",
      "journal-title": "Proc. Natl Acad. Sci. U. S. A."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "1219",
      "DOI": "10.1128/JVI.73.2.1219-1226.1999",
      "article-title": "Translation initiation at the CUU codon is mediated by the internal ribosome entry site of an insect picorna-like virus in vitro",
      "volume": "73",
      "author": "Sasaki",
      "year": "1999",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "181",
      "DOI": "10.1101/gad.1040803",
      "article-title": "Translation elongation after assembly of ribosomes on the Cricket paralysis virus internal ribosomal entry site without initiation factors or initiator tRNA",
      "volume": "17",
      "author": "Pestova",
      "year": "2003",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "266",
      "DOI": "10.1017/S1355838201001741",
      "article-title": "A tertiary structure model of the internal ribosome entry site (IRES) for methionine-independent initiation of translation",
      "volume": "7",
      "author": "Kanamori",
      "year": "2001",
      "journal-title": "RNA"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "889",
      "DOI": "10.1016/S0022-2836(02)01099-9",
      "article-title": "Factorless ribosome assembly on the internal ribosome entry site of cricket paralysis virus",
      "volume": "324",
      "author": "Jan",
      "year": "2002",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "2434",
      "DOI": "10.1093/nar/gkg336",
      "article-title": "Structural elements in the internal ribosome entry site of Plautia stali intestine virus responsible for binding with ribosomes",
      "volume": "31",
      "author": "Nishiyama",
      "year": "2003",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "332",
      "DOI": "10.1261/rna.7184705",
      "article-title": "A preformed compact ribosome-binding domain in the cricket paralysis-like virus IRES RNAs",
      "volume": "11",
      "author": "Costantino",
      "year": "2005",
      "journal-title": "RNA"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "1450",
      "DOI": "10.1126/science.1133281",
      "article-title": "Structural basis for ribosome recruitment and manipulation by a viral IRES RNA",
      "volume": "314",
      "author": "Pfingsten",
      "year": "2006",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "465",
      "DOI": "10.1016/j.cell.2004.08.001",
      "article-title": "Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes; the IRES functions as an RNA-based translation factor",
      "volume": "118",
      "author": "Spahn",
      "year": "2004",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "57",
      "DOI": "10.1038/nsmb1351",
      "article-title": "tRNA-mRNA mimicry drives translation initiation from a viral IRES",
      "volume": "15",
      "author": "Costantino",
      "year": "2008",
      "journal-title": "Nat. Struct. Mol. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "1092",
      "DOI": "10.1038/nsmb1177",
      "article-title": "Structure of the ribosome-bound cricket paralysis virus IRES RNA",
      "volume": "13",
      "author": "Schuler",
      "year": "2006",
      "journal-title": "Nat. Struct. Mol. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "906",
      "DOI": "10.1038/sj.embor.7400240",
      "article-title": "Position of the CrPV IRES on the 40S subunit and factor dependence of IRES/80S ribosome assembly",
      "volume": "5",
      "author": "Pestova",
      "year": "2004",
      "journal-title": "EMBO Rep."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "856",
      "DOI": "10.1016/j.jmb.2007.04.076",
      "article-title": "Conservation and diversity among the three-dimensional folds of the Dicistroviridae intergenic region IRESes",
      "volume": "370",
      "author": "Pfingsten",
      "year": "2007",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "1514",
      "DOI": "10.1093/nar/gkl1121",
      "article-title": "Eukaryotic ribosomal protein RPS25 interacts with the conserved loop region in a dicistroviral intergenic internal ribosome entry site",
      "volume": "35",
      "author": "Nishiyama",
      "year": "2007",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "7770",
      "DOI": "10.1074/jbc.M610887200",
      "article-title": "Binding mode of the first aminoacyl-tRNA in translation initiation mediated by Plautia stali intestine virus IRES",
      "volume": "282",
      "author": "Yamamoto",
      "year": "2007",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "234",
      "DOI": "10.1038/nsmb1060",
      "article-title": "The hybrid state of tRNA binding is an authentic translation elongation intermediate",
      "volume": "13",
      "author": "Dorner",
      "year": "2006",
      "journal-title": "Nat. Struct. Mol. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "7770",
      "DOI": "10.1074/jbc.M610887200",
      "article-title": "Binding mode of the first aminoacyl-tRNA in translation initiation mediated by Plautia stali intestine virus internal ribosome entry site",
      "volume": "282",
      "author": "Yamamoto",
      "year": "2007",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "1959",
      "DOI": "10.1126/science.1058409",
      "article-title": "Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit",
      "volume": "291",
      "author": "Spahn",
      "year": "2001",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib37",
      "doi-asserted-by": "crossref",
      "first-page": "123",
      "DOI": "10.1016/S0092-8674(03)00476-8",
      "article-title": "Locking and unlocking of ribosomal motions",
      "volume": "114",
      "author": "Valle",
      "year": "2003",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib38",
      "doi-asserted-by": "crossref",
      "first-page": "5041",
      "DOI": "10.1093/nar/20.19.5041",
      "article-title": "Secondary structure of the 5\u2032 nontranslated regions of hepatitis C virus and pestivirus genomic RNAs",
      "volume": "20",
      "author": "Brown",
      "year": "1992",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib39",
      "doi-asserted-by": "crossref",
      "first-page": "513",
      "DOI": "10.1006/jmbi.1999.3095",
      "article-title": "The hepatitis C virus internal ribosome entry site adopts an ion-dependent tertiary fold",
      "volume": "292",
      "author": "Kieft",
      "year": "1999",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib40",
      "doi-asserted-by": "crossref",
      "first-page": "226",
      "DOI": "10.1002/anie.200603807",
      "article-title": "Functional architecture of HCV IRES domain II stabilized by divalent metal ions in the crystal and in solution",
      "volume": "46",
      "author": "Dibrov",
      "year": "2007",
      "journal-title": "Angew. Chem. Int. Ed. Engl."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib41",
      "doi-asserted-by": "crossref",
      "first-page": "1033",
      "DOI": "10.1038/nsb1004",
      "article-title": "Structure of HCV IRES domain II determined by NMR",
      "volume": "10",
      "author": "Lukavsky",
      "year": "2003",
      "journal-title": "Nat. Struct. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib42",
      "first-page": "375",
      "article-title": "A conserved RNA structure within the HCV IRES eIF3-binding site",
      "volume": "9",
      "author": "Collier",
      "year": "2002",
      "journal-title": "Nat. Struct. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib43",
      "first-page": "370",
      "article-title": "Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation",
      "volume": "9",
      "author": "Kieft",
      "year": "2002",
      "journal-title": "Nat. Struct. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib44",
      "doi-asserted-by": "crossref",
      "first-page": "1105",
      "DOI": "10.1038/81951",
      "article-title": "Structures of two RNA domains essential for hepatitis C virus internal ribosome entry site function",
      "volume": "7",
      "author": "Lukavsky",
      "year": "2000",
      "journal-title": "Nat. Struct. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib45",
      "doi-asserted-by": "crossref",
      "first-page": "1423",
      "DOI": "10.1017/S1355838200000935",
      "article-title": "A potential RNA drug target in the hepatitis C virus internal ribosomal entry site",
      "volume": "6",
      "author": "Klinck",
      "year": "2000",
      "journal-title": "RNA"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib46",
      "doi-asserted-by": "crossref",
      "first-page": "805",
      "DOI": "10.1016/j.jmb.2004.08.095",
      "article-title": "Mutational and structural analysis of stem-loop IIIC of the hepatitis C virus and GB virus B internal ribosome entry sites",
      "volume": "343",
      "author": "Rijnbrand",
      "year": "2004",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib47",
      "doi-asserted-by": "crossref",
      "first-page": "795",
      "DOI": "10.1038/sj.emboj.7601549",
      "article-title": "HCV and CSFV IRES domain II mediate eIF2 release during 80S ribosome assembly",
      "volume": "26",
      "author": "Locker",
      "year": "2007",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib48",
      "doi-asserted-by": "crossref",
      "first-page": "194",
      "DOI": "10.1017/S1355838201001790",
      "article-title": "Mechanism of ribosome recruitment by hepatitis C IRES RNA",
      "volume": "7",
      "author": "Kieft",
      "year": "2001",
      "journal-title": "RNA"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib49",
      "doi-asserted-by": "crossref",
      "first-page": "6242",
      "DOI": "10.1128/JVI.74.14.6242-6250.2000",
      "article-title": "An enzymatic footprinting analysis of the interaction of 40S ribosomal subunits with the internal ribosomal entry site of hepatitis C virus",
      "volume": "74",
      "author": "Kolupaeva",
      "year": "2000",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib50",
      "doi-asserted-by": "crossref",
      "first-page": "1695",
      "DOI": "10.1016/j.str.2005.08.008",
      "article-title": "Structure of the hepatitis C virus IRES bound to the human 80S ribosome: remodeling of the HCV IRES",
      "volume": "13",
      "author": "Boehringer",
      "year": "2005",
      "journal-title": "Structure"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib51",
      "doi-asserted-by": "crossref",
      "first-page": "16990",
      "DOI": "10.1073/pnas.0407402101",
      "article-title": "Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA",
      "volume": "101",
      "author": "Ji",
      "year": "2004",
      "journal-title": "Proc. Natl Acad. Sci. U. S. A."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib52",
      "doi-asserted-by": "crossref",
      "first-page": "369",
      "DOI": "10.1016/j.cell.2004.09.038",
      "article-title": "The pathway of HCV IRES-mediated translation initiation",
      "volume": "119",
      "author": "Otto",
      "year": "2004",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib53",
      "doi-asserted-by": "crossref",
      "first-page": "913",
      "DOI": "10.1017/S1355838202022057",
      "article-title": "Ribosomal proteins mediate the hepatitis C virus IRES\u2013HeLa 40S interaction",
      "volume": "8",
      "author": "Otto",
      "year": "2002",
      "journal-title": "RNA"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib54",
      "doi-asserted-by": "crossref",
      "first-page": "1513",
      "DOI": "10.1126/science.1118977",
      "article-title": "Structural roles for human translation factor eIF3 in initiation of protein synthesis",
      "volume": "310",
      "author": "Siridechadilok",
      "year": "2005",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib55",
      "doi-asserted-by": "crossref",
      "first-page": "67",
      "DOI": "10.1101/gad.12.1.67",
      "article-title": "A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs",
      "volume": "12",
      "author": "Pestova",
      "year": "1998",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib56",
      "doi-asserted-by": "crossref",
      "first-page": "41",
      "DOI": "10.1016/j.molcel.2007.03.018",
      "article-title": "The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome",
      "volume": "26",
      "author": "Passmore",
      "year": "2007",
      "journal-title": "Mol. Cell"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib57",
      "doi-asserted-by": "crossref",
      "first-page": "29",
      "DOI": "10.1038/nrmicro1558",
      "article-title": "Structural and mechanistic insights into hepatitis C viral translation initiation",
      "volume": "5",
      "author": "Fraser",
      "year": "2007",
      "journal-title": "Nat. Rev. Microbiol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib58",
      "doi-asserted-by": "crossref",
      "first-page": "1935",
      "DOI": "10.1126/science.1131127",
      "article-title": "Structure of the 70S ribosome complexed with mRNA and tRNA",
      "volume": "313",
      "author": "Selmer",
      "year": "2006",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib59",
      "doi-asserted-by": "crossref",
      "first-page": "779",
      "DOI": "10.1261/rna.5208104",
      "article-title": "Structural variant of the intergenic internal ribosome entry site elements in dicistroviruses and computational search for their counterparts",
      "volume": "10",
      "author": "Hatakeyama",
      "year": "2004",
      "journal-title": "RNA"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib60",
      "doi-asserted-by": "crossref",
      "first-page": "915",
      "DOI": "10.1099/0022-1317-83-4-915",
      "article-title": "Shrimp Taura syndrome virus: genomic characterization and similarity with members of the genus Cricket paralysis-like viruses",
      "volume": "83",
      "author": "Mari",
      "year": "2002",
      "journal-title": "J. Gen. Virol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib61",
      "doi-asserted-by": "crossref",
      "first-page": "451",
      "DOI": "10.1128/JVI.71.1.451-457.1997",
      "article-title": "Internal entry of ribosomes is directed by the 5\u2032 noncoding region of classical swine fever virus and is dependent on the presence of an RNA pseudoknot upstream of the initiation codon",
      "volume": "71",
      "author": "Rijnbrand",
      "year": "1997",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib62",
      "doi-asserted-by": "crossref",
      "first-page": "4487",
      "DOI": "10.1128/JVI.78.9.4487-4497.2004",
      "article-title": "Functional and structural similarities between the internal ribosome entry sites of hepatitis C virus and porcine teschovirus, a picornavirus",
      "volume": "78",
      "author": "Pisarev",
      "year": "2004",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib63",
      "doi-asserted-by": "crossref",
      "first-page": "398",
      "DOI": "10.1006/jmbi.1994.1516",
      "article-title": "Starting window, a distinct element in the cap-independent internal initiation of translation on picornaviral RNA",
      "volume": "241",
      "author": "Pilipenko",
      "year": "1994",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib64",
      "doi-asserted-by": "crossref",
      "first-page": "685",
      "DOI": "10.1016/0042-6822(92)90523-R",
      "article-title": "Initiation of translation of human rhinovirus RNA: mapping the internal ribosome entry site",
      "volume": "188",
      "author": "Borman",
      "year": "1992",
      "journal-title": "Virology"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib65",
      "doi-asserted-by": "crossref",
      "first-page": "101",
      "DOI": "10.1146/annurev.biochem.75.103004.142733",
      "article-title": "The tmRNA system for translational surveillance and ribosome rescue",
      "volume": "76",
      "author": "Moore",
      "year": "2007",
      "journal-title": "Annu. Rev. Biochem."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib66",
      "doi-asserted-by": "crossref",
      "first-page": "1547",
      "DOI": "10.1007/PL00000795",
      "article-title": "Novel features in the tRNA-like world of plant viral RNAs",
      "volume": "58",
      "author": "Fechter",
      "year": "2001",
      "journal-title": "Cell. Mol. Life Sci."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib67",
      "doi-asserted-by": "crossref",
      "first-page": "133",
      "DOI": "10.2174/1389203023380837",
      "article-title": "Is tRNA binding or tRNA mimicry mandatory for translation factors?",
      "volume": "3",
      "author": "Kristensen",
      "year": "2002",
      "journal-title": "Curr. Protein Pept. Sci."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib68",
      "doi-asserted-by": "crossref",
      "first-page": "26844",
      "DOI": "10.1074/jbc.M304052200",
      "article-title": "Detection of tRNA-like structure through RNase P cleavage of viral internal ribosome entry site RNAs near the AUG start triplet",
      "volume": "278",
      "author": "Lyons",
      "year": "2003",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib69",
      "doi-asserted-by": "crossref",
      "first-page": "1487",
      "DOI": "10.1093/nar/gki290",
      "article-title": "Characterizing the function and structural organization of the 5\u2032 tRNA-like motif within the hepatitis C virus quasispecies",
      "volume": "33",
      "author": "Piron",
      "year": "2005",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib70",
      "doi-asserted-by": "crossref",
      "first-page": "849",
      "DOI": "10.1261/rna.506607",
      "article-title": "Characterization of a cyanobacterial RNase P ribozyme recognition motif in the IRES of foot-and-mouth disease virus reveals a unique structural element",
      "volume": "13",
      "author": "Serrano",
      "year": "2007",
      "journal-title": "RNA"
    },
    {
      "key": "10.1016/j.tibs.2008.04.007_bib71",
      "doi-asserted-by": "crossref",
      "first-page": "1183",
      "DOI": "10.1016/j.biochi.2007.05.009",
      "article-title": "RNase P RNA mediated cleavage: substrate recognition and catalysis",
      "volume": "89",
      "author": "Kirsebom",
      "year": "2007",
      "journal-title": "Biochimie"
    }
  ],
  "container-title": "Trends in Biochemical Sciences",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0968000408000911?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0968000408000911?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2020,
        5,
        6
      ]
    ],
    "date-time": "2020-05-06T00:41:01Z",
    "timestamp": 1588725661000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0968000408000911"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2008,
        6
      ]
    ]
  },
  "references-count": 71,
  "journal-issue": {
    "issue": "6",
    "published-print": {
      "date-parts": [
        [
          2008,
          6
        ]
      ]
    }
  },
  "alternative-id": [
    "S0968000408000911"
  ],
  "URL": "http://dx.doi.org/10.1016/j.tibs.2008.04.007",
  "relation": {},
  "ISSN": [
    "0968-0004"
  ],
  "subject": [],
  "container-title-short": "Trends in Biochemical Sciences",
  "published": {
    "date-parts": [
      [
        2008,
        6
      ]
    ]
  }
}