Tumor cells caught in the act of invading: their strategy for enhanced cell motility
10.1016/j.tcb.2005.01.003
Crossref journal-article
Elsevier BV
Trends in Cell Biology (78)
Bibliography

Wang, W., Goswami, S., Sahai, E., Wyckoff, J. B., Segall, J. E., & Condeelis, J. S. (2005). Tumor cells caught in the act of invading: their strategy for enhanced cell motility. Trends in Cell Biology, 15(3), 138–145.

Authors 6
  1. Weigang Wang (first)
  2. Sumanta Goswami (additional)
  3. Erik Sahai (additional)
  4. Jeffrey B. Wyckoff (additional)
  5. Jeffrey E. Segall (additional)
  6. John S. Condeelis (additional)
References 74 Referenced 218
  1. {'key': '10.1016/j.tcb.2005.01.003_bib1', 'first-page': '190', 'article-title': 'Biochemical mechanisms of tumor invasion and metastases', 'volume': '5', 'author': 'Liotta', 'year': '1987', 'journal-title': 'Clin. Physiol. Biochem.'} / Clin. Physiol. Biochem. / Biochemical mechanisms of tumor invasion and metastases by Liotta (1987)
  2. {'issue': 'Suppl. 18', 'key': '10.1016/j.tcb.2005.01.003_bib2', 'first-page': '5054s', 'article-title': 'Tumor invasion and metastasis: an imbalance of positive and negative regulation', 'volume': '51', 'author': 'Liotta', 'year': '1991', 'journal-title': 'Cancer Res.'} / Cancer Res. / Tumor invasion and metastasis: an imbalance of positive and negative regulation by Liotta (1991)
  3. {'key': '10.1016/j.tcb.2005.01.003_bib3', 'first-page': '147', 'article-title': 'Cell motility, a principal requirement for metastasis', 'volume': '59', 'author': 'Stracke', 'year': '1991', 'journal-title': 'EXS'} / EXS / Cell motility, a principal requirement for metastasis by Stracke (1991)
  4. 10.1038/35020106 / Nature / Genomic analysis of metastasis reveals an essential role for RhoC by Clark (2000)
  5. 10.1073/pnas.1232344100 / Proc. Natl. Acad. Sci. U. S. A. / A role for LIM kinase in cancer invasion by Yoshioka (2003)
  6. 10.1007/s002800051091 / Cancer Chemother. Pharmacol. / Critical determinants of cancer metastasis: rationale for therapy by Fidler (1999)
  7. 10.1002/(SICI)1097-0142(19971015)80:8+<1529::AID-CNCR2>3.0.CO;2-F / Cancer / General mechanisms of metastasis by Woodhouse (1997)
  8. 10.1158/0008-5472.CAN-04-1136 / Cancer Res. / Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors by Wang (2004)
  9. 10.1016/S1357-2725(00)00035-2 / Int. J. Biochem. Cell Biol. / Intracellular signaling events at the leading edge of migrating cells by Maghazachi (2000)
  10. 10.1038/nrc1231 / Nat. Rev. Cancer / Intravital imaging of cell movement in tumours by Condeelis (2003)
  11. {'key': '10.1016/j.tcb.2005.01.003_bib11', 'first-page': '6278', 'article-title': 'Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling', 'volume': '62', 'author': 'Wang', 'year': '2002', 'journal-title': 'Cancer Res.'} / Cancer Res. / Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling by Wang (2002)
  12. 10.1038/35077241 / Nature / The microenvironment of the tumour–host interface by Liotta (2001)
  13. 10.1126/science.887927 / Science / Metastasis results from preexisting variant cells within a malignant tumor by Fidler (1977)
  14. 10.1038/ng1060 / Nat. Genet. / A molecular signature of metastasis in primary solid tumors by Ramaswamy (2003)
  15. 10.1126/science.274.5289.998 / Science / Laser capture microdissection by Emmert-Buck (1996)
  16. 10.1002/path.892 / J. Pathol. / Use of laser capture microdissection, cDNA microarrays, and tissue microarrays in advancing our understanding of prostate cancer by Rubin (2001)
  17. 10.1016/S1535-6108(03)00132-6 / Cancer Cell / A multigenic program mediating breast cancer metastasis to bone by Kang (2003)
  18. 10.1002/ijc.1564 / Int. J. Cancer / Differential display analysis of breast carcinoma cells enriched by immunomagnetic target cell selection: gene expression profiles in bone marrow target cells by Ree (2002)
  19. {'key': '10.1016/j.tcb.2005.01.003_bib19', 'first-page': '2504', 'article-title': 'A critical step in metastasis: in vivo analysis of intravasation at the primary tumor', 'volume': '60', 'author': 'Wyckoff', 'year': '2000', 'journal-title': 'Cancer Res.'} / Cancer Res. / A critical step in metastasis: in vivo analysis of intravasation at the primary tumor by Wyckoff (2000)
  20. {'key': '10.1016/j.tcb.2005.01.003_bib20', 'first-page': '5401', 'article-title': 'The collection of the motile population of cells from a living tumor', 'volume': '60', 'author': 'Wyckoff', 'year': '2000', 'journal-title': 'Cancer Res.'} / Cancer Res. / The collection of the motile population of cells from a living tumor by Wyckoff (2000)
  21. {'key': '10.1016/j.tcb.2005.01.003_bib21', 'series-title': '5th Abercrombie Symposium on Cell Behaviour', 'article-title': 'Chemotaxis of cancer cells during invasion and metastasis', 'author': 'Condeelis', 'year': '2003'} / 5th Abercrombie Symposium on Cell Behaviour / Chemotaxis of cancer cells during invasion and metastasis by Condeelis (2003)
  22. 10.1016/S0959-8049(01)00231-3 / Eur. J. Cancer / EGFR and cancer prognosis by Nicholson (2001)
  23. 10.1016/0140-6736(93)91348-P / Lancet / Secretion of epidermal growth factor by macrophages associated with breast carcinoma by O'Sullivan (1993)
  24. 10.1002/ijc.10481 / Int. J. Cancer / Peripheral lymph node stromal cells can promote growth and tumorigenicity of breast carcinoma cells through the release of IGF-I and EGF by LeBedis (2002)
  25. 10.1186/1472-6750-3-13 / BMC Biotechnol. / Gene expression analysis on small numbers of invasive cells collected by chemotaxis from primary mammary tumors of the mouse by Wang (2003)
  26. 10.1158/0008-5472.CAN-04-1449 / Cancer Res. / A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors by Wyckoff (2004)
  27. Goswami, S. et al. Macrophages promote the invasion of carcinoma cells via a paracrine loop. Cancer Res. (in press)
  28. 10.1038/nrc1256 / Nat. Rev. Cancer / Tumour-educated macrophages promote tumour progression and metastasis by Pollard (2004)
  29. 10.1084/jem.193.6.727 / J. Exp. Med. / Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy by Lin (2001)
  30. 10.1158/0008-5472.CAN-04-2027 / Cancer Res. / Breast cancer cells isolated by chemotaxis from primary tumors show increased survival and resistance to chemotherapy by Goswami (2004)
  31. 10.1074/jbc.R300010200 / J. Biol. Chem. / Eukaryotic chemotaxis: distinctions between directional sensing and polarization by Devreotes (2003)
  32. 10.1083/jcb.200405156 / J. Cell Biol. / Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation by Mouneimne (2004)
  33. {'key': '10.1016/j.tcb.2005.01.003_bib33', 'first-page': '2632', 'article-title': 'Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer', 'volume': '9', 'author': 'Kamai', 'year': '2003', 'journal-title': 'Clin. Cancer Res.'} / Clin. Cancer Res. / Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer by Kamai (2003)
  34. 10.1002/ijc.20094 / Int. J. Cancer / Human Mena protein, a serex-defined antigen overexpressed in breast cancer eliciting both humoral and CD8+ T-cell immune response by Di Modugno (2004)
  35. 10.1038/modpathol.3800062 / Mod. Pathol. / Involvement of Arp2/3 complex in the process of colorectal carcinogenesis by Otsubo (2004)
  36. 10.1074/jbc.M306196200 / J. Biol. Chem. / LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: implications in prostate cancer by Davila (2003)
  37. 10.1126/science.1094561 / Science / Cofilin promotes actin polymerization and defines the direction of cell motility by Ghosh (2004)
  38. 10.1073/pnas.121146098 / Proc. Natl. Acad. Sci. U. S. A. / The physiological significance of β-actin mRNA localization in determining cell polarity and directional motility by Shestakova (2001)
  39. 10.1038/nature01423 / Nature / Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity by Etienne-Manneville (2003)
  40. 10.1016/j.ceb.2003.11.010 / Curr. Opin. Cell Biol. / Cortical control of microtubule stability and polarization by Gundersen (2004)
  41. {'key': '10.1016/j.tcb.2005.01.003_bib41', 'first-page': '1202', 'article-title': 'Correlation of β-actin messenger RNA localization with metastatic potential in rat adenocarcinoma cell lines', 'volume': '59', 'author': 'Shestakova', 'year': '1999', 'journal-title': 'Cancer Res.'} / Cancer Res. / Correlation of β-actin messenger RNA localization with metastatic potential in rat adenocarcinoma cell lines by Shestakova (1999)
  42. 10.1126/science.284.5415.765 / Science / A cell's sense of direction by Parent (1999)
  43. 10.1016/S1534-5807(02)00292-7 / Dev. Cell / Temporal and spatial regulation of chemotaxis by Iijima (2002)
  44. 10.1016/S0022-4804(03)00202-6 / J. Surg. Res. / Therapeutic significance of Y-27632, a Rho-kinase inhibitor, on the established liver fibrosis by Murata (2003)
  45. 10.1016/S0014-2999(02)02869-8 / Eur. J. Pharmacol. / Wf-536 prevents tumor metastasis by inhibiting both tumor motility and angiogenic actions by Nakajima (2003)
  46. 10.1038/415530a / Nature / Gene expression profiling predicts clinical outcome of breast cancer by van't Veer (2002)
  47. 10.1016/S0092-8674(00)81683-9 / Cell / The hallmarks of cancer by Hanahan (2000)
  48. 10.1038/418823a / Nature / A progression puzzle by Bernards (2002)
  49. 10.1016/S0140-6736(02)09838-0 / Lancet / Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer by Klein (2002)
  50. 10.1038/nrc725 / Nat. Rev. Cancer / Rho-GTPases and cancer by Sahai (2002)
  51. {'key': '10.1016/j.tcb.2005.01.003_bib51', 'first-page': '1359', 'article-title': 'Requirement of RhoA activity for increased nuclear factor κB activity and PC-3 human prostate cancer cell invasion', 'volume': '63', 'author': 'Hodge', 'year': '2003', 'journal-title': 'Cancer Res.'} / Cancer Res. / Requirement of RhoA activity for increased nuclear factor κB activity and PC-3 human prostate cancer cell invasion by Hodge (2003)
  52. 10.1038/sj.onc.1206910 / Oncogene / Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells by Fernandis (2004)
  53. 10.1023/A:1006188129423 / Breast Cancer Res. Treat. / Differentially expressed genes associated with the metastatic phenotype in breast cancer by Kirschmann (1999)
  54. 10.1002/1097-0215(200002)9999:9999<::AID-IJC1094>3.0.CO;2-M / Int. J. Cancer / Gene expression profiling of malignant mesothelioma cell lines: cDNA array study by Kettunen (2001)
  55. {'key': '10.1016/j.tcb.2005.01.003_bib55', 'first-page': '2309', 'article-title': 'Increased expression of S100A4, a metastasis-associated gene, in human colorectal adenocarcinomas', 'volume': '3', 'author': 'Takenaga', 'year': '1997', 'journal-title': 'Clin. Cancer Res.'} / Clin. Cancer Res. / Increased expression of S100A4, a metastasis-associated gene, in human colorectal adenocarcinomas by Takenaga (1997)
  56. {'key': '10.1016/j.tcb.2005.01.003_bib56', 'first-page': '2015', 'article-title': 'Identification of rat pancreatic carcinoma genes associated with lymphogenous metastasis', 'volume': '22', 'author': 'Tarbe', 'year': '2002', 'journal-title': 'Anticancer Res.'} / Anticancer Res. / Identification of rat pancreatic carcinoma genes associated with lymphogenous metastasis by Tarbe (2002)
  57. {'key': '10.1016/j.tcb.2005.01.003_bib57', 'first-page': '6418', 'article-title': 'RhoGDI2 is an invasion and metastasis suppressor gene in human cancer', 'volume': '62', 'author': 'Gildea', 'year': '2002', 'journal-title': 'Cancer Res.'} / Cancer Res. / RhoGDI2 is an invasion and metastasis suppressor gene in human cancer by Gildea (2002)
  58. {'key': '10.1016/j.tcb.2005.01.003_bib58', 'first-page': '3750', 'article-title': 'Metastasis-associated differences in gene expression in a murine model of osteosarcoma', 'volume': '61', 'author': 'Khanna', 'year': '2001', 'journal-title': 'Cancer Res.'} / Cancer Res. / Metastasis-associated differences in gene expression in a murine model of osteosarcoma by Khanna (2001)
  59. 10.1038/sj.neo.7900185 / Neoplasia / Genome-wide screening of genes showing altered expression in liver metastases of human colorectal cancers by cDNA microarray by Yanagawa (2001)
  60. 10.1158/1078-0432.CCR-03-0210 / Clin. Cancer Res. / Pak-1 expression increases with progression of colorectal carcinomas to metastasis by Carter (2004)
  61. 10.1038/sj.bjc.6601050 / Br. J. Cancer / FAK overexpression is correlated with tumour invasiveness and lymph node metastasis in oesophageal squamous cell carcinoma by Miyazaki (2003)
  62. 10.1007/BF03402191 / Mol. Med. / Changes in tumorigenesis- and angiogenesis-related gene transcript abundance profiles in ovarian cancer detected by tailored high density cDNA arrays by Martoglio (2000)
  63. 10.1038/sj.onc.1205570 / Oncogene / Expression profiling of microdissected pancreatic adenocarcinomas by Crnogorac-Jurcevic (2002)
  64. 10.1038/sj.onc.1203703 / Oncogene / Distinct pattern of expression of differentiation and growth-related genes in squamous cell carcinomas of the head and neck revealed by the use of laser capture microdissection and cDNA arrays by Leethanakul (2000)
  65. 10.1093/carcin/bgh159 / Carcinogenesis / Enhanced expression of 14-3-3σ in pancreatic cancer and its role in cell cycle regulation and apoptosis by Guweidhi (2004)
  66. 10.1097/01.sla.0000128681.76786.07 / Ann. Surg. / Inflammatory mechanisms contributing to pancreatic cancer development by Farrow (2004)
  67. 10.1002/pmic.200300466 / Proteomics / Application of laser capture microdissection combined with two-dimensional electrophoresis for the discovery of differentially regulated proteins in pancreatic ductal adenocarcinoma by Shekouh (2003)
  68. 10.1002/pmic.200300382 / Proteomics / An approach to the proteomic analysis of a breast cancer cell line (SKBR-3) by Wu (2003)
  69. 10.1186/1477-3163-2-5 / J. Carcinog. / BRCA1/2 mutation screening and LOH analysis of lung adenocarcinoma tissue in a multiple-cancer patient with a strong family history of breast cancer by Boettger (2003)
  70. 10.1002/cncr.10354 / Cancer / Macrophage migration inhibitory factor evaluation compared with prostate specific antigen as a biomarker in patients with prostate carcinoma by Meyer-Siegler (2002)
  71. 10.1002/1615-9861(200201)2:1<76::AID-PROT76>3.0.CO;2-O / Proteomics / Proteomic analysis and identification of new biomarkers and therapeutic targets for invasive ovarian cancer by Jones (2002)
  72. 10.1038/nbt0402-387 / Nat. Biotechnol. / Combined transcriptome and genome analysis of single micrometastatic cells by Klein (2002)
  73. {'key': '10.1016/j.tcb.2005.01.003_bib73', 'first-page': '2503', 'article-title': 'Neural Wiskott–Aldrich syndrome protein is involved in hepatocyte growth factor-induced migration, invasion, and tubulogenesis of epithelial cells', 'volume': '62', 'author': 'Yamaguchi', 'year': '2002', 'journal-title': 'Cancer Res.'} / Cancer Res. / Neural Wiskott–Aldrich syndrome protein is involved in hepatocyte growth factor-induced migration, invasion, and tubulogenesis of epithelial cells by Yamaguchi (2002)
  74. 10.1038/nrc1075 / Nat Rev. Cancer / Tumour-cell invasion and migration: diversity and escape mechanisms by Friedl (2003)
Dates
Type When
Created 20 years, 6 months ago (Feb. 11, 2005, 4:16 a.m.)
Deposited 6 years, 7 months ago (Jan. 28, 2019, 8:52 a.m.)
Indexed 3 months, 3 weeks ago (May 13, 2025, 5:25 a.m.)
Issued 20 years, 6 months ago (March 1, 2005)
Published 20 years, 6 months ago (March 1, 2005)
Published Print 20 years, 6 months ago (March 1, 2005)
Funders 0

None

@article{Wang_2005, title={Tumor cells caught in the act of invading: their strategy for enhanced cell motility}, volume={15}, ISSN={0962-8924}, url={http://dx.doi.org/10.1016/j.tcb.2005.01.003}, DOI={10.1016/j.tcb.2005.01.003}, number={3}, journal={Trends in Cell Biology}, publisher={Elsevier BV}, author={Wang, Weigang and Goswami, Sumanta and Sahai, Erik and Wyckoff, Jeffrey B. and Segall, Jeffrey E. and Condeelis, John S.}, year={2005}, month=mar, pages={138–145} }