DOI: 10.1016/j.str.2013.09.012. Structure of the Dodecameric Yersinia enterocolitica Secretin YscC and Its Trypsin-Resistant Core

Structure of the Dodecameric Yersinia enterocolitica Secretin YscC and Its Trypsin-Resistant Core

10.1016/j.str.2013.09.012

Crossref journal-article

Elsevier BV

Structure (78)

Bibliography

Kowal, J., Chami, M., Ringler, P., MÃ¼ller, S. A., Kudryashev, M., CastaÃ±o-DÃez, D., Amstutz, M., Cornelis, G. R., Stahlberg, H., & Engel, A. (2013). Structure of the Dodecameric Yersinia enterocolitica Secretin YscC and Its Trypsin-Resistant Core. Structure, 21(12), 2152â2161.

Authors 10

Julia Kowal (first)
Mohamed Chami (additional)
Philippe Ringler (additional)
Shirley A. Müller (additional)
Mikhail Kudryashev (additional)
Daniel Castaño-Díez (additional)
Marlise Amstutz (additional)
Guy R. Cornelis (additional)
Henning Stahlberg (additional)
Andreas Engel (additional)

References 51 Referenced 35

10.1046/j.1365-2958.1996.344874.x / Mol. Microbiol. / Flagellar assembly in Salmonella typhimurium by Aizawa (1996)
10.1073/pnas.1013888108 / Proc. Natl. Acad. Sci. USA / Translocation of surface-localized effectors in type III secretion by Akopyan (2011)
10.1371/journal.ppat.1003307 / PLoS Pathog. / A refined model of the prototypical Salmonella SPI-1 T3SS basal body reveals the molecular basis for its assembly by Bergeron (2013)
10.1371/journal.ppat.1002923 / PLoS Pathog. / Structure and assembly of a trans-periplasmic channel for type IV pili in Neisseria meningitidis by Berry (2012)
10.1046/j.1365-2958.1998.00677.x / Mol. Microbiol. / Formation of oligomeric rings by XcpQ and PilQ, which are involved in protein transport across the outer membrane of Pseudomonas aeruginosa by Bitter (1998)
10.1128/JB.186.16.5366-5375.2004 / J. Bacteriol. / Role of the pilot protein YscW in the biogenesis of the YscC secretin in Yersinia enterocolitica by Burghout (2004)
10.1128/JB.186.14.4645-4654.2004 / J. Bacteriol. / Structure and electrophysiological properties of the YscC secretin from the type III secretion system of Yersinia enterocolitica by Burghout (2004)
10.1074/jbc.M110.212688 / J. Biol. Chem. / Structure and function of PilQ, a secretin of the DNA transporter from the thermophilic bacterium Thermus thermophilus HB27 by Burkhardt (2011)
10.1074/jbc.M111.334912 / J. Biol. Chem. / Unusual N-terminal ααβαββα fold of PilQ from Thermus thermophilus mediates ring formation and is essential for piliation by Burkhardt (2012)
10.1016/j.jsb.2011.12.017 / J. Struct. Biol. / Dynamo: a flexible, user-friendly development tool for subtomogram averaging of cryo-EM data in high-performance computing environments by Castaño-Díez (2012)
10.1074/jbc.M504463200 / J. Biol. Chem. / Structural insights into the secretin PulD and its trypsin-resistant core by Chami (2005)
10.1128/CMR.00013-07 / Clin. Microbiol. Rev. / Type III secretion systems and disease by Coburn (2007)
10.1074/jbc.M405971200 / J. Biol. Chem. / Structure of the Neisseria meningitidis outer membrane PilQ secretin complex at 12 A resolution by Collins (2004)
10.1073/pnas.97.16.8778 / Proc. Natl. Acad. Sci. USA / Molecular and cell biology aspects of plague by Cornelis (2000)
10.1038/nrmicro1526 / Nat. Rev. Microbiol. / The type III secretion injectisome by Cornelis (2006)
10.1038/nrmicro2091 / Nat. Rev. Microbiol. / Symbiotic use of pathogenic strategies: rhizobial protein secretion systems by Deakin (2009)
10.1038/emboj.2010.84 / EMBO J. / Deciphering the assembly of the Yersinia type III secretion injectisome by Diepold (2010)
10.1111/j.1365-2958.2011.07830.x / Mol. Microbiol. / The assembly of the export apparatus (YscR,S,T,U,V) of the Yersinia type III secretion apparatus occurs independently of other structural components and involves the formation of an YscV oligomer by Diepold (2011)
10.1002/j.1460-2075.1993.tb05775.x / EMBO J. / The portal protein of bacteriophage SPP1: a DNA pump with 13-fold symmetry by Dube (1993)
10.1073/pnas.1116126109 / Proc. Natl. Acad. Sci. USA / Structure of a type III secretion needle at 7-Å resolution provides insights into its assembly and signaling mechanisms by Fujii (2012)
10.1007/BF00283883 / Mol. Gen. Genet. / A superfamily of proteins involved in different secretion pathways in gram-negative bacteria: modular structure and specificity of the N-terminal domain by Genin (1994)
10.1038/sj.emboj.7601402 / EMBO J. / Bacterial outer membrane secretin PulD assembles and inserts into the inner membrane in the absence of its pilotin by Guilvout (2006)
10.1016/j.jmb.2008.06.055 / J. Mol. Biol. / In vitro multimerization and membrane insertion of bacterial outer membrane secretin PulD by Guilvout (2008)
10.1002/j.1460-2075.1996.tb00434.x / EMBO J. / Insertion of an outer membrane protein in Escherichia coli requires a chaperone-like protein by Hardie (1996)
10.1038/nsmb.1599 / Nat. Struct. Mol. Biol. / Three-dimensional reconstruction of the Shigella T3SS transmembrane regions reveals 12-fold symmetry and novel features throughout by Hodgkinson (2009)
10.1371/journal.pone.0016624 / PLoS ONE / Structural characterization of outer membrane components of the type IV pili system in pathogenic Neisseria by Jain (2011)
10.1073/pnas.200209497 / Proc. Natl. Acad. Sci. USA / Contribution of Salmonella typhimurium type III secretion components to needle complex formation by Kimbrough (2000)
10.1016/S1286-4579(01)01512-X / Microbes Infect. / Assembly of the type III secretion needle complex of Salmonella typhimurium by Kimbrough (2002)
10.1016/j.str.2008.11.011 / Structure / Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody by Korotkov (2009)
10.1016/j.tibs.2011.04.002 / Trends Biochem. Sci. / Secretins: dynamic channels for protein transport across membranes by Korotkov (2011)
10.1371/journal.ppat.1002228 / PLoS Pathog. / Structural and functional studies on the interaction of GspC and GspD in the type II secretion system by Korotkov (2011)
10.1098/rstb.2011.0205 / Philos. Trans. R. Soc. Lond. B Biol. Sci. / The blueprint of the type-3 injectisome by Kosarewicz (2012)
10.1046/j.1365-2958.1997.6141981.x / Mol. Microbiol. / The outer membrane component, YscC, of the Yop secretion machinery of Yersinia enterocolitica forms a ring-shaped multimeric complex by Koster (1997)
10.7554/eLife.00792 / eLife / In situ structural analysis of the Yersinia enterocolitica injectisome by Kudryashev (2013)
10.1038/nature11079 / Nature / Atomic model of the type III secretion system needle by Loquet (2012)
10.1016/j.bbamcr.2004.04.005 / Biochim. Biophys. Acta / Type III flagellar protein export and flagellar assembly by Macnab (2004)
10.1126/science.1102610 / Science / Structural insights into the assembly of the type III secretion needle complex by Marlovits (2004)
10.2533/chimia.2006.749 / Chimia (Aarau) / Biological scanning transmission electron microscopy: imaging and single molecule mass determination by Müller (2006)
10.1016/0304-3991(92)90022-C / Ultramicroscopy / Factors influencing the precision of quantitative scanning transmission electron microscopy by Müller (1992)
10.1016/S0022-2836(02)01246-9 / J. Mol. Biol. / Structure of the filamentous phage pIV multimer by cryo-electron microscopy by Opalka (2003)
10.1006/jsbi.2001.4369 / J. Struct. Biol. / A novel neural network technique for analysis and classification of EM single-particle images by Pascual-Montano (2001)
10.1016/S1047-8477(02)00008-4 / J. Struct. Biol. / Quantitative self-organizing maps for clustering electron tomograms by Pascual-Montano (2002)
10.1038/nsmb.1910 / Nat. Struct. Mol. Biol. / Structure of the cholera toxin secretion channel in its closed state by Reichow (2010)
10.1016/j.jmb.2003.07.013 / J. Mol. Biol. / Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy by Rosenthal (2003)
10.1128/JB.01137-10 / J. Bacteriol. / A C-terminal region of Yersinia pestis YscD binds the outer membrane secretin YscC by Ross (2011)
10.1128/mBio.00158-10 / MBio / Interactions of the transmembrane polymeric rings of the Salmonella enterica serovar Typhimurium type III secretion system by Sanowar (2010)
10.1126/science.1199358 / Science / Three-dimensional model of Salmonella’s needle complex at subnanometer resolution by Schraidt (2011)
10.1038/nsmb.1603 / Nat. Struct. Mol. Biol. / A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system by Spreter (2009)
10.1074/jbc.M112.432096 / J. Biol. Chem. / New insights into the assembly of bacterial secretins: structural studies of the periplasmic domain of XcpQ from Pseudomonas aeruginosa by Van der Meeren (2013)
10.1073/pnas.1008053107 / Proc. Natl. Acad. Sci. USA / Organization and coordinated assembly of the type III secretion export apparatus by Wagner (2010)
10.1074/jbc.M112.346338 / J. Biol. Chem. / Cysteine scanning mutagenesis and disulfide mapping analysis of arrangement of GspC and GspD protomers within the type 2 secretion system by Wang (2012)

Dates

Type	When
Created	11 years, 10 months ago (Oct. 24, 2013, 6:32 p.m.)
Deposited	6 years ago (July 31, 2019, 4:40 a.m.)
Indexed	2 months ago (June 28, 2025, 12:01 p.m.)
Issued	11 years, 8 months ago (Dec. 1, 2013)
Published	11 years, 8 months ago (Dec. 1, 2013)
Published Print	11 years, 8 months ago (Dec. 1, 2013)

Funders 0

None

BibTeX

@article{Kowal_2013, title={Structure of the Dodecameric Yersinia enterocolitica Secretin YscC and Its Trypsin-Resistant Core}, volume={21}, ISSN={0969-2126}, url={http://dx.doi.org/10.1016/j.str.2013.09.012}, DOI={10.1016/j.str.2013.09.012}, number={12}, journal={Structure}, publisher={Elsevier BV}, author={Kowal, Julia and Chami, Mohamed and Ringler, Philippe and Müller, Shirley A. and Kudryashev, Mikhail and Castaño-Díez, Daniel and Amstutz, Marlise and Cornelis, Guy R. and Stahlberg, Henning and Engel, Andreas}, year={2013}, month=dec, pages={2152–2161} }

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      "author": "Akopyan",
      "year": "2011",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
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      "article-title": "A refined model of the prototypical Salmonella SPI-1 T3SS basal\u00a0body reveals the molecular basis for its assembly",
      "volume": "9",
      "author": "Bergeron",
      "year": "2013",
      "journal-title": "PLoS Pathog."
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      "first-page": "e1002923",
      "DOI": "10.1371/journal.ppat.1002923",
      "article-title": "Structure and assembly of a trans-periplasmic channel for type IV pili in Neisseria meningitidis",
      "volume": "8",
      "author": "Berry",
      "year": "2012",
      "journal-title": "PLoS Pathog."
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    {
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      "first-page": "209",
      "DOI": "10.1046/j.1365-2958.1998.00677.x",
      "article-title": "Formation of oligomeric rings by XcpQ and PilQ, which are involved in protein transport across the outer membrane of Pseudomonas aeruginosa",
      "volume": "27",
      "author": "Bitter",
      "year": "1998",
      "journal-title": "Mol. Microbiol."
    },
    {
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      "doi-asserted-by": "crossref",
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      "DOI": "10.1128/JB.186.16.5366-5375.2004",
      "article-title": "Role of the pilot protein YscW in the biogenesis of the YscC secretin in Yersinia enterocolitica",
      "volume": "186",
      "author": "Burghout",
      "year": "2004",
      "journal-title": "J.\u00a0Bacteriol."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "4645",
      "DOI": "10.1128/JB.186.14.4645-4654.2004",
      "article-title": "Structure and electrophysiological properties of the YscC secretin from the type III secretion system of Yersinia enterocolitica",
      "volume": "186",
      "author": "Burghout",
      "year": "2004",
      "journal-title": "J.\u00a0Bacteriol."
    },
    {
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      "doi-asserted-by": "crossref",
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      "author": "Burkhardt",
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      "journal-title": "J.\u00a0Biol. Chem."
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      "volume": "287",
      "author": "Burkhardt",
      "year": "2012",
      "journal-title": "J.\u00a0Biol. Chem."
    },
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      "author": "Casta\u00f1o-D\u00edez",
      "year": "2012",
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      "author": "Chami",
      "year": "2005",
      "journal-title": "J.\u00a0Biol. Chem."
    },
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      "article-title": "Type III secretion systems and disease",
      "volume": "20",
      "author": "Coburn",
      "year": "2007",
      "journal-title": "Clin. Microbiol. Rev."
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    {
      "key": "10.1016/j.str.2013.09.012_bib13",
      "doi-asserted-by": "crossref",
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      "DOI": "10.1074/jbc.M405971200",
      "article-title": "Structure of the Neisseria meningitidis outer membrane PilQ secretin complex at 12 A resolution",
      "volume": "279",
      "author": "Collins",
      "year": "2004",
      "journal-title": "J.\u00a0Biol. Chem."
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      "author": "Cornelis",
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      "journal-title": "Proc. Natl. Acad. Sci. USA"
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      "article-title": "The type III secretion injectisome",
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      "author": "Cornelis",
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      "journal-title": "Nat. Rev. Microbiol."
    },
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      "first-page": "312",
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      "author": "Deakin",
      "year": "2009",
      "journal-title": "Nat. Rev. Microbiol."
    },
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      "first-page": "1928",
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      "volume": "29",
      "author": "Diepold",
      "year": "2010",
      "journal-title": "EMBO J."
    },
    {
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      "first-page": "502",
      "DOI": "10.1111/j.1365-2958.2011.07830.x",
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      "author": "Diepold",
      "year": "2011",
      "journal-title": "Mol. Microbiol."
    },
    {
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      "doi-asserted-by": "crossref",
      "first-page": "1303",
      "DOI": "10.1002/j.1460-2075.1993.tb05775.x",
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      "volume": "12",
      "author": "Dube",
      "year": "1993",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "4461",
      "DOI": "10.1073/pnas.1116126109",
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      "volume": "109",
      "author": "Fujii",
      "year": "2012",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "112",
      "DOI": "10.1007/BF00283883",
      "article-title": "A superfamily of proteins involved in different secretion pathways in gram-negative bacteria: modular structure and specificity of the N-terminal domain",
      "volume": "243",
      "author": "Genin",
      "year": "1994",
      "journal-title": "Mol. Gen. Genet."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "5241",
      "DOI": "10.1038/sj.emboj.7601402",
      "article-title": "Bacterial outer membrane secretin PulD assembles and inserts into the inner membrane in the absence of its pilotin",
      "volume": "25",
      "author": "Guilvout",
      "year": "2006",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "13",
      "DOI": "10.1016/j.jmb.2008.06.055",
      "article-title": "In\u00a0vitro multimerization and membrane insertion of bacterial outer membrane secretin PulD",
      "volume": "382",
      "author": "Guilvout",
      "year": "2008",
      "journal-title": "J.\u00a0Mol. Biol."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "978",
      "DOI": "10.1002/j.1460-2075.1996.tb00434.x",
      "article-title": "Insertion of an outer membrane protein in Escherichia coli requires a chaperone-like protein",
      "volume": "15",
      "author": "Hardie",
      "year": "1996",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "477",
      "DOI": "10.1038/nsmb.1599",
      "article-title": "Three-dimensional reconstruction of the Shigella T3SS transmembrane regions reveals 12-fold symmetry and novel features throughout",
      "volume": "16",
      "author": "Hodgkinson",
      "year": "2009",
      "journal-title": "Nat. Struct. Mol. Biol."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "e16624",
      "DOI": "10.1371/journal.pone.0016624",
      "article-title": "Structural characterization of outer membrane components of the type IV pili system in pathogenic Neisseria",
      "volume": "6",
      "author": "Jain",
      "year": "2011",
      "journal-title": "PLoS ONE"
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "11008",
      "DOI": "10.1073/pnas.200209497",
      "article-title": "Contribution of Salmonella typhimurium type III secretion components to needle complex formation",
      "volume": "97",
      "author": "Kimbrough",
      "year": "2000",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "75",
      "DOI": "10.1016/S1286-4579(01)01512-X",
      "article-title": "Assembly of the type III secretion needle complex of Salmonella typhimurium",
      "volume": "4",
      "author": "Kimbrough",
      "year": "2002",
      "journal-title": "Microbes Infect."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "255",
      "DOI": "10.1016/j.str.2008.11.011",
      "article-title": "Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody",
      "volume": "17",
      "author": "Korotkov",
      "year": "2009",
      "journal-title": "Structure"
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "433",
      "DOI": "10.1016/j.tibs.2011.04.002",
      "article-title": "Secretins: dynamic channels for protein transport across membranes",
      "volume": "36",
      "author": "Korotkov",
      "year": "2011",
      "journal-title": "Trends Biochem. Sci."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "e1002228",
      "DOI": "10.1371/journal.ppat.1002228",
      "article-title": "Structural and functional studies on the interaction of GspC and GspD in the type II secretion system",
      "volume": "7",
      "author": "Korotkov",
      "year": "2011",
      "journal-title": "PLoS Pathog."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "1140",
      "DOI": "10.1098/rstb.2011.0205",
      "article-title": "The blueprint of the type-3 injectisome",
      "volume": "367",
      "author": "Kosarewicz",
      "year": "2012",
      "journal-title": "Philos. Trans. R. Soc. Lond. B Biol. Sci."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "789",
      "DOI": "10.1046/j.1365-2958.1997.6141981.x",
      "article-title": "The outer membrane component, YscC, of the Yop secretion machinery of Yersinia enterocolitica forms a ring-shaped multimeric complex",
      "volume": "26",
      "author": "Koster",
      "year": "1997",
      "journal-title": "Mol. Microbiol."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "e00792",
      "DOI": "10.7554/eLife.00792",
      "article-title": "In situ structural analysis of the Yersinia enterocolitica injectisome",
      "volume": "2",
      "author": "Kudryashev",
      "year": "2013",
      "journal-title": "eLife"
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "276",
      "DOI": "10.1038/nature11079",
      "article-title": "Atomic model of the type III secretion system needle",
      "volume": "486",
      "author": "Loquet",
      "year": "2012",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "207",
      "DOI": "10.1016/j.bbamcr.2004.04.005",
      "article-title": "Type III flagellar protein export and flagellar assembly",
      "volume": "1694",
      "author": "Macnab",
      "year": "2004",
      "journal-title": "Biochim. Biophys. Acta"
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib37",
      "doi-asserted-by": "crossref",
      "first-page": "1040",
      "DOI": "10.1126/science.1102610",
      "article-title": "Structural insights into the assembly of the type III secretion needle complex",
      "volume": "306",
      "author": "Marlovits",
      "year": "2004",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib38",
      "doi-asserted-by": "crossref",
      "first-page": "749",
      "DOI": "10.2533/chimia.2006.749",
      "article-title": "Biological scanning transmission electron microscopy: imaging and single molecule mass determination",
      "volume": "60",
      "author": "M\u00fcller",
      "year": "2006",
      "journal-title": "Chimia (Aarau)"
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib39",
      "doi-asserted-by": "crossref",
      "first-page": "317",
      "DOI": "10.1016/0304-3991(92)90022-C",
      "article-title": "Factors influencing the precision of quantitative scanning transmission electron microscopy",
      "volume": "46",
      "author": "M\u00fcller",
      "year": "1992",
      "journal-title": "Ultramicroscopy"
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib40",
      "doi-asserted-by": "crossref",
      "first-page": "461",
      "DOI": "10.1016/S0022-2836(02)01246-9",
      "article-title": "Structure of the filamentous phage pIV multimer by cryo-electron microscopy",
      "volume": "325",
      "author": "Opalka",
      "year": "2003",
      "journal-title": "J.\u00a0Mol. Biol."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib41",
      "doi-asserted-by": "crossref",
      "first-page": "233",
      "DOI": "10.1006/jsbi.2001.4369",
      "article-title": "A novel neural network technique for analysis and classification of EM single-particle images",
      "volume": "133",
      "author": "Pascual-Montano",
      "year": "2001",
      "journal-title": "J.\u00a0Struct. Biol."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib42",
      "doi-asserted-by": "crossref",
      "first-page": "114",
      "DOI": "10.1016/S1047-8477(02)00008-4",
      "article-title": "Quantitative self-organizing maps for clustering electron tomograms",
      "volume": "138",
      "author": "Pascual-Montano",
      "year": "2002",
      "journal-title": "J.\u00a0Struct. Biol."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib43",
      "doi-asserted-by": "crossref",
      "first-page": "1226",
      "DOI": "10.1038/nsmb.1910",
      "article-title": "Structure of the cholera toxin secretion channel in its closed state",
      "volume": "17",
      "author": "Reichow",
      "year": "2010",
      "journal-title": "Nat. Struct. Mol. Biol."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib44",
      "doi-asserted-by": "crossref",
      "first-page": "721",
      "DOI": "10.1016/j.jmb.2003.07.013",
      "article-title": "Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy",
      "volume": "333",
      "author": "Rosenthal",
      "year": "2003",
      "journal-title": "J.\u00a0Mol. Biol."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib45",
      "doi-asserted-by": "crossref",
      "first-page": "2276",
      "DOI": "10.1128/JB.01137-10",
      "article-title": "A C-terminal region of Yersinia pestis YscD binds the outer membrane secretin YscC",
      "volume": "193",
      "author": "Ross",
      "year": "2011",
      "journal-title": "J.\u00a0Bacteriol."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib46",
      "doi-asserted-by": "crossref",
      "DOI": "10.1128/mBio.00158-10",
      "article-title": "Interactions of the transmembrane polymeric rings of the Salmonella enterica serovar Typhimurium type III secretion system",
      "volume": "1",
      "author": "Sanowar",
      "year": "2010",
      "journal-title": "MBio"
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib47",
      "doi-asserted-by": "crossref",
      "first-page": "1192",
      "DOI": "10.1126/science.1199358",
      "article-title": "Three-dimensional model of Salmonella\u2019s needle complex at subnanometer resolution",
      "volume": "331",
      "author": "Schraidt",
      "year": "2011",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib48",
      "doi-asserted-by": "crossref",
      "first-page": "468",
      "DOI": "10.1038/nsmb.1603",
      "article-title": "A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system",
      "volume": "16",
      "author": "Spreter",
      "year": "2009",
      "journal-title": "Nat. Struct. Mol. Biol."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib49",
      "doi-asserted-by": "crossref",
      "first-page": "1214",
      "DOI": "10.1074/jbc.M112.432096",
      "article-title": "New insights into the assembly of bacterial secretins: structural studies of the periplasmic domain of XcpQ from Pseudomonas aeruginosa",
      "volume": "288",
      "author": "Van der Meeren",
      "year": "2013",
      "journal-title": "J.\u00a0Biol. Chem."
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib50",
      "doi-asserted-by": "crossref",
      "first-page": "17745",
      "DOI": "10.1073/pnas.1008053107",
      "article-title": "Organization and coordinated assembly of the type\u00a0III secretion export apparatus",
      "volume": "107",
      "author": "Wagner",
      "year": "2010",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.str.2013.09.012_bib51",
      "doi-asserted-by": "crossref",
      "first-page": "19082",
      "DOI": "10.1074/jbc.M112.346338",
      "article-title": "Cysteine scanning mutagenesis and disulfide mapping analysis of arrangement of GspC and GspD protomers within the type 2 secretion system",
      "volume": "287",
      "author": "Wang",
      "year": "2012",
      "journal-title": "J.\u00a0Biol. Chem."
    }
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