DOI: 10.1016/j.str.2004.11.006. A Vinculin Binding Domain from the Talin Rod Unfolds to Form a Complex with the Vinculin Head

A Vinculin Binding Domain from the Talin Rod Unfolds to Form a Complex with the Vinculin Head

10.1016/j.str.2004.11.006

Crossref journal-article

Elsevier BV

Structure (78)

Bibliography

Fillingham, I., Gingras, A. R., Papagrigoriou, E., Patel, B., Emsley, J., Critchley, D. R., Roberts, G. C. K., & Barsukov, I. L. (2005). A Vinculin Binding Domain from the Talin Rod Unfolds to Form a Complex with the Vinculin Head. Structure, 13(1), 65â74.

Authors 8

Ian Fillingham (first)
Alexandre R. Gingras (additional)
Evangelos Papagrigoriou (additional)
Bipin Patel (additional)
Jonas Emsley (additional)
David R. Critchley (additional)
Gordon C.K. Roberts (additional)
Igor L. Barsukov (additional)

References 50 Referenced 98

10.1242/jcs.108.10.3317 / J. Cell Sci. / Down regulation of talin alters cell adhesion and the processing of the α5β1 integrin by Albiges-Rizo (1995)
10.1016/S0092-8674(00)81549-4 / Cell / Crystal structure of the vinculin tail suggests a pathway for activation by Bakolitsa (1999)
10.1074/jbc.M303850200 / J. Biol. Chem. / Phosphatidylinositol phosphate kinase type 1γ and β1-integrin cytoplasmic domain bind to the same region in the talin FERM domain by Barsukov (2003)
10.1042/0264-6021:3410257 / Biochem. J. / Talin contains three similar vinculin-binding sites predicted to form an amphipathic helix by Bass (1999)
10.1002/(SICI)1097-0169(1997)36:4<363::AID-CM6>3.0.CO;2-6 / Cell Motil. Cytoskeleton / Monoclonal antibodies recognizing the N- and C-terminal regions of talin disrupt actin stress fibers when microinjected into human fibroblasts by Bolton (1997)
10.1016/S1534-5807(02)00290-3 / Dev. Cell / Talin is essential for integrin function in Drosophila by Brown (2002)
{'key': '10.1016/j.str.2004.11.006_bib7', 'first-page': '905', 'article-title': 'Crystallography and NMR system (CNS): a new software system for macromolecular structure determination', 'volume': 'D54', 'author': 'Brunger', 'year': '1998', 'journal-title': 'Acta Crystallogr.'} / Acta Crystallogr. / Crystallography and NMR system (CNS): a new software system for macromolecular structure determination by Brunger (1998)
10.1242/jcs.01014 / J. Cell Sci. / Integrin activation by Calderwood (2004)
10.1074/jbc.270.28.16995 / J. Biol. Chem. / Interaction of focal adhesion kinase with the cytoskeletal protein talin by Chen (1995)
10.1023/A:1008392405740 / J. Biolmol. NMR / Protein backbone angle restraints from searching a database for chemical shift and sequence homology by Cornilescu (1999)
10.1242/jcs.00705 / J. Cell Sci. / Talin loss-of-function uncovers roles in cell contractility and migration in C. elegans by Cram (2003)
10.1007/BF00197809 / J. Biomol. NMR / Nmrpipe—a multidimensional spectral processing system based on Unix pipes by Delaglio (1995)
10.1038/nature01147 / Nature / Recruitment and regulation of phosphatidylinositol phosphate kinase type Iγ by the FERM domain of talin by Di Paolo (2002)
10.1016/S1097-2765(02)00823-7 / Mol. Cell / Structural determinants of integrin recognition by talin by Garcia-Alvarez (2003)
10.1083/jcb.200302001 / J. Cell Biol. / Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation by Giannone (2003)
10.1038/381531a0 / Nature / Regulation of vinculin binding to talin and actin by phosphatidylinositol-4–5-bisphosphate by Gilmore (1996)
10.1242/jcs.109.11.2715 / J. Cell Sci. / Talin contains three actin-binding sites, each of which is adjacent to a vinculin-binding site by Hemmings (1996)
10.1016/S0022-2836(02)00241-3 / J. Mol. Biol. / Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA by Herrmann (2002)
10.1093/nar/25.1.231 / Nucleic Acids Res. / DALI/FSSP classification of three dimensional protein folds by Holm (1997)
10.1016/0263-7855(96)00018-5 / J. Mol. Graph. / VMD—visual molecular dynamics by Humphrey (1996)
10.1016/S0960-9822(98)70199-X / Curr. Biol. / The interaction of the cell-contact proteins VASP and vinculin is regulated by phosphatidylinositol-4,5-bisphosphate by Huttelmaier (1998)
10.1074/jbc.M403076200 / J. Biol. Chem. / Structural basis for amplifying vinculin activation by talin by Izard (2004)
10.1038/nature02281 / Nature / Vinculin activation by talin through helical bundle conversion by Izard (2004)
10.1038/nature01805 / Nature / Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin by Jiang (2003)
10.1016/0962-8924(96)10022-2 / Trends Cell Biol. / Crosstalk between cell adhesion molecules: vinculin as a paradigm for regulation by conformation by Jockusch (1996)
10.1007/BF00404272 / J. Biomol. NMR / NMR VIEW—a computer-program for the visualization and analysis of nmr data by Johnson (1994)
10.1074/jbc.275.1.95 / J. Biol. Chem. / Actin activates a cryptic dimerization potential of the vinculin tail domain by Johnson (2000)
10.1126/science.1084174 / Science / Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins by Kim (2003)
10.1107/S0021889891004399 / J. Appl. Crystallogr. / MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures by Kraulis (1991)
10.1007/BF00228148 / J. Biomol. NMR / AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR by Laskowski (1996)
10.1038/nature01082 / Nature / Type Iγ phosphatidylinositol phosphate kinase targets and regulates focal adhesions by Ling (2002)
10.1016/S0076-6879(01)39310-2 / Methods Enzymol. / Assigning ambiguous NOEs with ARIA by Linge (2001)
10.1242/jcs.113.20.3563 / J. Cell Sci. / Integrin cytoplasmic domain-binding proteins by Liu (2000)
10.1023/A:1011254402785 / J. Biomol. NMR / A method for efficient isotopic labeling of recombinant proteins by Marley (2001)
10.1074/jbc.M102373200 / J. Biol. Chem. / Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides by Martel (2001)
10.1073/pnas.94.11.5679 / Proc. Natl. Acad. Sci. USA / The I/LWEQ module: a conserved sequence that signifies F-actin binding in functionally diverse proteins from yeast to mammals by McCann (1997)
10.1006/jsbi.1999.4094 / J. Struct. Biol. / XtalView Xfit—a versatile program for manipulating atomic coordinates and electron density by McRee (1999)
10.1002/1097-0177(2000)9999:9999<::AID-DVDY1079>3.0.CO;2-Y / Dev. Dyn. / Disruption of the talin gene arrests mouse development at the gastrulation stage by Monkley (2000)
10.1016/S0076-6879(01)39311-4 / Methods Enzymol. / Automatic determination of protein backbone resonance assignments from triple resonance NMR data by Moseley (2001)
10.1021/bi00445a003 / Biochemistry / Stereospecific nuclear magnetic resonance assignments of the methyl groups of valine and leucine in the DNA-binding domain of the 434 repressor by biosynthetically directed fractional carbon-13 labeling by Neri (1989)
10.1242/jcs.102.4.753 / J. Cell Sci. / Microinjection of antibodies against talin inhibits the spreading and migration of fibroblasts by Nuckolls (1992)
10.1038/sj.emboj.7600285 / EMBO J. / Activation of a vinculin binding site in the talin rod involves rearrangement of a five helix bundle by Papagrigoriou (2004)
10.1083/jcb.142.4.1121 / J. Cell Biol. / Disruption of the talin gene compromises focal adhesion assembly in undifferentiated but not differentiated ES cells by Priddle (1998)
10.1016/S0079-6565(98)00025-9 / Prog. NMR Spectrosc. / Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients by Sattler (1999)
10.1126/science.1086652 / Science / Talin binding to integrin beta tails: a final common step in integrin activation by Tadokoro (2003)
10.1074/jbc.M400947200 / J. Biol. Chem. / A fluorescence cell biology approach to map the second integrin binding site of talin to a 130-amino acid sequence within the rodd domain by Tremuth (2004)
10.1111/j.1432-1033.1997.0430a.x / Eur. J. Biochem. / Energy-filtered electron microscopy reveals that talin is a highly flexible protein composed of a series of globular domains by Winkler (1997)
10.1007/BF00175245 / J. Biomol. NMR / The 13C chemical-shift index: a simple method for the identification of protein secondary structure using 13C chemical-shift data by Wishart (1994)
10.1074/jbc.M108587200 / J. Biol. Chem. / Localization of an integrin binding site to the C terminus of talin by Xing (2001)
10.1242/dev.125.2.327 / Development / Vinculin knockout results in heart and brain defects during embryonic development by Xu (1998)

Dates

Type	When
Created	20 years, 7 months ago (Jan. 12, 2005, 7:18 a.m.)
Deposited	4 years, 1 month ago (July 3, 2021, 6:46 p.m.)
Indexed	9 months ago (Nov. 19, 2024, 10:52 a.m.)
Issued	20 years, 7 months ago (Jan. 1, 2005)
Published	20 years, 7 months ago (Jan. 1, 2005)
Published Print	20 years, 7 months ago (Jan. 1, 2005)

Funders 0

None

BibTeX

@article{Fillingham_2005, title={A Vinculin Binding Domain from the Talin Rod Unfolds to Form a Complex with the Vinculin Head}, volume={13}, ISSN={0969-2126}, url={http://dx.doi.org/10.1016/j.str.2004.11.006}, DOI={10.1016/j.str.2004.11.006}, number={1}, journal={Structure}, publisher={Elsevier BV}, author={Fillingham, Ian and Gingras, Alexandre R. and Papagrigoriou, Evangelos and Patel, Bipin and Emsley, Jonas and Critchley, David R. and Roberts, Gordon C.K. and Barsukov, Igor L.}, year={2005}, month=jan, pages={65–74} }

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      "article-title": "Crystal structure of the vinculin tail suggests a pathway for activation",
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      "author": "Bakolitsa",
      "year": "1999",
      "journal-title": "Cell"
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    {
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      "doi-asserted-by": "crossref",
      "first-page": "31202",
      "DOI": "10.1074/jbc.M303850200",
      "article-title": "Phosphatidylinositol phosphate kinase type 1\u03b3 and \u03b21-integrin cytoplasmic domain bind to the same region in the talin FERM domain",
      "volume": "278",
      "author": "Barsukov",
      "year": "2003",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib4",
      "doi-asserted-by": "crossref",
      "first-page": "257",
      "DOI": "10.1042/0264-6021:3410257",
      "article-title": "Talin contains three similar vinculin-binding sites predicted to form an amphipathic helix",
      "volume": "341",
      "author": "Bass",
      "year": "1999",
      "journal-title": "Biochem. J."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib5",
      "doi-asserted-by": "crossref",
      "first-page": "363",
      "DOI": "10.1002/(SICI)1097-0169(1997)36:4<363::AID-CM6>3.0.CO;2-6",
      "article-title": "Monoclonal antibodies recognizing the N- and C-terminal regions of talin disrupt actin stress fibers when microinjected into human fibroblasts",
      "volume": "36",
      "author": "Bolton",
      "year": "1997",
      "journal-title": "Cell Motil. Cytoskeleton"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib6",
      "doi-asserted-by": "crossref",
      "first-page": "569",
      "DOI": "10.1016/S1534-5807(02)00290-3",
      "article-title": "Talin is essential for integrin function in Drosophila",
      "volume": "3",
      "author": "Brown",
      "year": "2002",
      "journal-title": "Dev. Cell"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib7",
      "first-page": "905",
      "article-title": "Crystallography and NMR system (CNS): a new software system for macromolecular structure determination",
      "volume": "D54",
      "author": "Brunger",
      "year": "1998",
      "journal-title": "Acta Crystallogr."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib8",
      "doi-asserted-by": "crossref",
      "first-page": "657",
      "DOI": "10.1242/jcs.01014",
      "article-title": "Integrin activation",
      "volume": "117",
      "author": "Calderwood",
      "year": "2004",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "16995",
      "DOI": "10.1074/jbc.270.28.16995",
      "article-title": "Interaction of focal adhesion kinase with the cytoskeletal protein talin",
      "volume": "270",
      "author": "Chen",
      "year": "1995",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "289",
      "DOI": "10.1023/A:1008392405740",
      "article-title": "Protein backbone angle restraints from searching a database for chemical shift and sequence homology",
      "volume": "13",
      "author": "Cornilescu",
      "year": "1999",
      "journal-title": "J. Biolmol. NMR"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib11",
      "doi-asserted-by": "crossref",
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      "volume": "116",
      "author": "Cram",
      "year": "2003",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "277",
      "DOI": "10.1007/BF00197809",
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      "volume": "6",
      "author": "Delaglio",
      "year": "1995",
      "journal-title": "J. Biomol. NMR"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "85",
      "DOI": "10.1038/nature01147",
      "article-title": "Recruitment and regulation of phosphatidylinositol phosphate kinase type I\u03b3 by the FERM domain of talin",
      "volume": "420",
      "author": "Di Paolo",
      "year": "2002",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib14",
      "doi-asserted-by": "crossref",
      "first-page": "49",
      "DOI": "10.1016/S1097-2765(02)00823-7",
      "article-title": "Structural determinants of integrin recognition by talin",
      "volume": "11",
      "author": "Garcia-Alvarez",
      "year": "2003",
      "journal-title": "Mol. Cell"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "409",
      "DOI": "10.1083/jcb.200302001",
      "article-title": "Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation",
      "volume": "163",
      "author": "Giannone",
      "year": "2003",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib16",
      "doi-asserted-by": "crossref",
      "first-page": "531",
      "DOI": "10.1038/381531a0",
      "article-title": "Regulation of vinculin binding to talin and actin by phosphatidylinositol-4\u20135-bisphosphate",
      "volume": "381",
      "author": "Gilmore",
      "year": "1996",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib17",
      "doi-asserted-by": "crossref",
      "first-page": "2715",
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      "article-title": "Talin contains three actin-binding sites, each of which is adjacent to a vinculin-binding site",
      "volume": "109",
      "author": "Hemmings",
      "year": "1996",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "209",
      "DOI": "10.1016/S0022-2836(02)00241-3",
      "article-title": "Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA",
      "volume": "319",
      "author": "Herrmann",
      "year": "2002",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "231",
      "DOI": "10.1093/nar/25.1.231",
      "article-title": "DALI/FSSP classification of three dimensional protein folds",
      "volume": "25",
      "author": "Holm",
      "year": "1997",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "33",
      "DOI": "10.1016/0263-7855(96)00018-5",
      "article-title": "VMD\u2014visual molecular dynamics",
      "volume": "14",
      "author": "Humphrey",
      "year": "1996",
      "journal-title": "J. Mol. Graph."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "479",
      "DOI": "10.1016/S0960-9822(98)70199-X",
      "article-title": "The interaction of the cell-contact proteins VASP and vinculin is regulated by phosphatidylinositol-4,5-bisphosphate",
      "volume": "8",
      "author": "Huttelmaier",
      "year": "1998",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "27667",
      "DOI": "10.1074/jbc.M403076200",
      "article-title": "Structural basis for amplifying vinculin activation by talin",
      "volume": "279",
      "author": "Izard",
      "year": "2004",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "171",
      "DOI": "10.1038/nature02281",
      "article-title": "Vinculin activation by talin through helical bundle conversion",
      "volume": "427",
      "author": "Izard",
      "year": "2004",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "334",
      "DOI": "10.1038/nature01805",
      "article-title": "Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin",
      "volume": "424",
      "author": "Jiang",
      "year": "2003",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "311",
      "DOI": "10.1016/0962-8924(96)10022-2",
      "article-title": "Crosstalk between cell adhesion molecules: vinculin as a paradigm for regulation by conformation",
      "volume": "6",
      "author": "Jockusch",
      "year": "1996",
      "journal-title": "Trends Cell Biol."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "603",
      "DOI": "10.1007/BF00404272",
      "article-title": "NMR VIEW\u2014a computer-program for the visualization and analysis of nmr data",
      "volume": "4",
      "author": "Johnson",
      "year": "1994",
      "journal-title": "J. Biomol. NMR"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "95",
      "DOI": "10.1074/jbc.275.1.95",
      "article-title": "Actin activates a cryptic dimerization potential of the vinculin tail domain",
      "volume": "275",
      "author": "Johnson",
      "year": "2000",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "1720",
      "DOI": "10.1126/science.1084174",
      "article-title": "Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins",
      "volume": "301",
      "author": "Kim",
      "year": "2003",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "946",
      "DOI": "10.1107/S0021889891004399",
      "article-title": "MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures",
      "volume": "24",
      "author": "Kraulis",
      "year": "1991",
      "journal-title": "J. Appl. Crystallogr."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "477",
      "DOI": "10.1007/BF00228148",
      "article-title": "AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR",
      "volume": "8",
      "author": "Laskowski",
      "year": "1996",
      "journal-title": "J. Biomol. NMR"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "89",
      "DOI": "10.1038/nature01082",
      "article-title": "Type I\u03b3 phosphatidylinositol phosphate kinase targets and regulates focal adhesions",
      "volume": "420",
      "author": "Ling",
      "year": "2002",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "71",
      "DOI": "10.1016/S0076-6879(01)39310-2",
      "article-title": "Assigning ambiguous NOEs with ARIA",
      "volume": "339",
      "author": "Linge",
      "year": "2001",
      "journal-title": "Methods Enzymol."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "3563",
      "DOI": "10.1242/jcs.113.20.3563",
      "article-title": "Integrin cytoplasmic domain-binding proteins",
      "volume": "113",
      "author": "Liu",
      "year": "2000",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "71",
      "DOI": "10.1023/A:1011254402785",
      "article-title": "A method for efficient isotopic labeling of recombinant proteins",
      "volume": "20",
      "author": "Marley",
      "year": "2001",
      "journal-title": "J. Biomol. NMR"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "21217",
      "DOI": "10.1074/jbc.M102373200",
      "article-title": "Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides",
      "volume": "276",
      "author": "Martel",
      "year": "2001",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "5679",
      "DOI": "10.1073/pnas.94.11.5679",
      "article-title": "The I/LWEQ module: a conserved sequence that signifies F-actin binding in functionally diverse proteins from yeast to mammals",
      "volume": "94",
      "author": "McCann",
      "year": "1997",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib37",
      "doi-asserted-by": "crossref",
      "first-page": "156",
      "DOI": "10.1006/jsbi.1999.4094",
      "article-title": "XtalView Xfit\u2014a versatile program for manipulating atomic coordinates and electron density",
      "volume": "125",
      "author": "McRee",
      "year": "1999",
      "journal-title": "J. Struct. Biol."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib38",
      "doi-asserted-by": "crossref",
      "first-page": "560",
      "DOI": "10.1002/1097-0177(2000)9999:9999<::AID-DVDY1079>3.0.CO;2-Y",
      "article-title": "Disruption of the talin gene arrests mouse development at the gastrulation stage",
      "volume": "219",
      "author": "Monkley",
      "year": "2000",
      "journal-title": "Dev. Dyn."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib39",
      "doi-asserted-by": "crossref",
      "first-page": "91",
      "DOI": "10.1016/S0076-6879(01)39311-4",
      "article-title": "Automatic determination of protein backbone resonance assignments from triple resonance NMR data",
      "volume": "339",
      "author": "Moseley",
      "year": "2001",
      "journal-title": "Methods Enzymol."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib40",
      "doi-asserted-by": "crossref",
      "first-page": "7510",
      "DOI": "10.1021/bi00445a003",
      "article-title": "Stereospecific nuclear magnetic resonance assignments of the methyl groups of valine and leucine in the DNA-binding domain of the 434 repressor by biosynthetically directed fractional carbon-13 labeling",
      "volume": "28",
      "author": "Neri",
      "year": "1989",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib41",
      "doi-asserted-by": "crossref",
      "first-page": "753",
      "DOI": "10.1242/jcs.102.4.753",
      "article-title": "Microinjection of antibodies against talin inhibits the spreading and migration of fibroblasts",
      "volume": "102",
      "author": "Nuckolls",
      "year": "1992",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib42",
      "doi-asserted-by": "crossref",
      "first-page": "2942",
      "DOI": "10.1038/sj.emboj.7600285",
      "article-title": "Activation of a vinculin binding site in the talin rod involves rearrangement of a five helix bundle",
      "volume": "23",
      "author": "Papagrigoriou",
      "year": "2004",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib43",
      "doi-asserted-by": "crossref",
      "first-page": "1121",
      "DOI": "10.1083/jcb.142.4.1121",
      "article-title": "Disruption of the talin gene compromises focal adhesion assembly in undifferentiated but not differentiated ES cells",
      "volume": "142",
      "author": "Priddle",
      "year": "1998",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib44",
      "doi-asserted-by": "crossref",
      "first-page": "93",
      "DOI": "10.1016/S0079-6565(98)00025-9",
      "article-title": "Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients",
      "volume": "34",
      "author": "Sattler",
      "year": "1999",
      "journal-title": "Prog. NMR Spectrosc."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib45",
      "doi-asserted-by": "crossref",
      "first-page": "103",
      "DOI": "10.1126/science.1086652",
      "article-title": "Talin binding to integrin beta tails: a final common step in integrin activation",
      "volume": "302",
      "author": "Tadokoro",
      "year": "2003",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib46",
      "doi-asserted-by": "crossref",
      "first-page": "22258",
      "DOI": "10.1074/jbc.M400947200",
      "article-title": "A fluorescence cell biology approach to map the second integrin binding site of talin to a 130-amino acid sequence within the rodd domain",
      "volume": "279",
      "author": "Tremuth",
      "year": "2004",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib47",
      "doi-asserted-by": "crossref",
      "first-page": "430",
      "DOI": "10.1111/j.1432-1033.1997.0430a.x",
      "article-title": "Energy-filtered electron microscopy reveals that talin is a highly flexible protein composed of a series of globular domains",
      "volume": "243",
      "author": "Winkler",
      "year": "1997",
      "journal-title": "Eur. J. Biochem."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib48",
      "doi-asserted-by": "crossref",
      "first-page": "171",
      "DOI": "10.1007/BF00175245",
      "article-title": "The 13C chemical-shift index: a simple method for the identification of protein secondary structure using 13C chemical-shift data",
      "volume": "4",
      "author": "Wishart",
      "year": "1994",
      "journal-title": "J. Biomol. NMR"
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib49",
      "doi-asserted-by": "crossref",
      "first-page": "44373",
      "DOI": "10.1074/jbc.M108587200",
      "article-title": "Localization of an integrin binding site to the C terminus of talin",
      "volume": "276",
      "author": "Xing",
      "year": "2001",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.str.2004.11.006_bib50",
      "doi-asserted-by": "crossref",
      "first-page": "327",
      "DOI": "10.1242/dev.125.2.327",
      "article-title": "Vinculin knockout results in heart and brain defects during embryonic development",
      "volume": "125",
      "author": "Xu",
      "year": "1998",
      "journal-title": "Development"
    }
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