DOI: 10.1016/j.pupt.2012.02.002. Safety and pharmacokinetics of multiple doses of aclidinium bromide administered twice daily in healthy volunteers

Safety and pharmacokinetics of multiple doses of aclidinium bromide administered twice daily in healthy volunteers

10.1016/j.pupt.2012.02.002

Crossref journal-article

Elsevier BV

Pulmonary Pharmacology & Therapeutics (78)

Bibliography

Lasseter, K., Dilzer, S., Jansat, J. M., Garcia Gil, E., Caracta, C. F., & Ortiz, S. (2012). Safety and pharmacokinetics of multiple doses of aclidinium bromide administered twice daily in healthy volunteers. Pulmonary Pharmacology & Therapeutics, 25(2), 193â199.

Authors 6

K. Lasseter (first)
S. Dilzer (additional)
J.M. Jansat (additional)
E. Garcia Gil (additional)
C.F. Caracta (additional)
S. Ortiz (additional)

References 18 Referenced 22

Centers for Disease Control and Prevention. Division of vital statistics. deaths: preliminary data for 2008. [Internet]. 2010 Dec [cited 2011 February 3]. Available from: http://www.cdc.gov/nchs/data/nvsr/nvsr59/nvsr59_02.pdf.
World Health Organization (WHO). The global burden of disease: 2004 update. [Internet]. 2008 [cited 2011 January 14]. Available from: http://www.who.int/healthinfo/global_burden_disease/GBD_report_2004update_full.pdf.
{'issue': 'Suppl. 12A', 'key': '10.1016/j.pupt.2012.02.002_bib3', 'first-page': '24S', 'article-title': 'The role of anticholinergics in chronic obstructive pulmonary disease', 'volume': '117', 'author': 'Barnes', 'year': '2004', 'journal-title': 'Am J Med'} / Am J Med / The role of anticholinergics in chronic obstructive pulmonary disease by Barnes (2004)
10.1164/rccm.200703-456SO / Am J Respir Crit Care Med / Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary by Rabe (2007)
10.1016/j.ejps.2010.01.004 / Eur J Pharm Sci / Aclidinium bromide, a new, long-acting, inhaled muscarinic antagonist: in vitro plasma inactivation and pharmacological activity of its main metabolites by Sentellas (2010)
10.1124/dmd.109.031724 / Drug Metab Dispos / Identification of the human enzymes responsible for the enzymatic hydrolysis of aclidinium bromide by Alberti (2010)
10.5414/CPP47460 / Int J Clin Pharmacol Ther / Safety and pharmacokinetics of single doses of aclidinium bromide, a novel long-acting, inhaled antimuscarinic, in healthy subjects by Jansat (2009)
10.1177/0091270011406281 / J Clin Pharmacol / Safety and tolerability of aclidinium administered intravenously and absolute bioavailability of inhaled aclidinium in healthy male subjects by Ortiz (2011)
10.1177/0091270009336353 / J Clin Pharmacol / Safety and pharmacokinetics of multiple doses of aclidinium bromide, a novel long-acting muscarinic antagonist for the treatment of chronic obstructive pulmonary disease, in healthy participants by Jansat (2009)
10.1177/0091270010374471 / J Clin Pharmacol / Aclidinium bromide, a long-acting antimuscarinic, does not affect QT interval in healthy subjects by Lasseter (2010)
Jones PW, Rennard SI, Agusti A, Chanez P, Magnussen H, Fabbri L, et al. Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease. Respir Res [Internet]. 2011 April 26 [cited 2011 April 27];12:55. Available from: http://respiratory-research.com/content/12/1/55. (10.1186/1465-9921-12-55)
10.1183/09031936.00099306 / Eur Respir J / Outcomes for COPD pharmacological trials: from lung function to biomarkers by Cazzola (2008)
10.1124/jpet.109.151639 / J Pharmacol Exp Ther / Characterization of aclidinium bromide, a novel inhaled muscarinic antagonist, with long duration of action and a favorable pharmacological profile by Gavalda (2009)
{'key': '10.1016/j.pupt.2012.02.002_bib14', 'article-title': 'Efficacy of aclidinium bromide 400 μg BID compared with placebo and tiotropium in patients with moderate-to-severe COPD', 'author': 'Fuhr', 'year': '2011', 'journal-title': 'Chest'} / Chest / Efficacy of aclidinium bromide 400 μg BID compared with placebo and tiotropium in patients with moderate-to-severe COPD by Fuhr (2011)
10.1183/09031936.02.00269802 / Eur Respir J / A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease by Casaburi (2002)
{'key': '10.1016/j.pupt.2012.02.002_bib16', 'series-title': 'Spiriva [package insert]', 'year': '2011'} / Spiriva [package insert] (2011)
10.3109/15412555.2012.661492 / COPD / Efficacy and safety of a 12-week treatment with twice-daily aclidinium bromide in COPD patients (ACCORD COPD I) by Kerwin (2012)
{'key': '10.1016/j.pupt.2012.02.002_bib18', 'first-page': 'A6350', 'article-title': 'Aclidinium bromide in patients with chronic obstructive pulmonary disease: efficacy and safety results from ATTAIN', 'volume': '183', 'author': 'Jones', 'year': '2011', 'journal-title': 'Am J Respir Crit Care Med'} / Am J Respir Crit Care Med / Aclidinium bromide in patients with chronic obstructive pulmonary disease: efficacy and safety results from ATTAIN by Jones (2011)

Dates

Type	When
Created	13 years, 6 months ago (Feb. 15, 2012, 12:45 p.m.)
Deposited	6 years, 2 months ago (June 23, 2019, 3:36 p.m.)
Indexed	11 months, 2 weeks ago (Sept. 8, 2024, 8:18 a.m.)
Issued	13 years, 4 months ago (April 1, 2012)
Published	13 years, 4 months ago (April 1, 2012)
Published Print	13 years, 4 months ago (April 1, 2012)

Funders 0

None

BibTeX

@article{Lasseter_2012, title={Safety and pharmacokinetics of multiple doses of aclidinium bromide administered twice daily in healthy volunteers}, volume={25}, ISSN={1094-5539}, url={http://dx.doi.org/10.1016/j.pupt.2012.02.002}, DOI={10.1016/j.pupt.2012.02.002}, number={2}, journal={Pulmonary Pharmacology & Therapeutics}, publisher={Elsevier BV}, author={Lasseter, K. and Dilzer, S. and Jansat, J.M. and Garcia Gil, E. and Caracta, C.F. and Ortiz, S.}, year={2012}, month=apr, pages={193–199} }

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