Crossref
journal-article
Elsevier BV
Neuron (78)
References
54
Referenced
249
10.1074/jbc.M601421200
/ J. Biol. Chem. / Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2 by Andrews-Zwilling (2006)10.1038/22768
/ Nature / Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles by Augustin (1999)10.1042/bj3370363
/ Biochem. J. / Differential expression of two novel Munc13 proteins in rat brain by Augustin (1999)10.1038/nsmb1001
/ Nat. Struct. Mol. Biol. / A minimal domain responsible for Munc13 activity by Basu (2005)10.1074/jbc.272.4.2520
/ J. Biol. Chem. / Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin by Betz (1997)10.1016/S0896-6273(01)00272-0
/ Neuron / Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming by Betz (2001)10.1074/jbc.270.42.25273
/ J. Biol. Chem. / Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins by Brose (1995)10.1016/j.neuron.2004.05.014
/ Neuron / Multiple roles for the active zone protein RIM1alpha in late stages of neurotransmitter release by Calakos (2004)10.1038/41574
/ Nature / Rab3A is essential for mossy fibre long-term potentiation in the hippocampus by Castillo (1997)10.1038/415327a
/ Nature / RIM1α is required for presynaptic long-term potentiation by Castillo (2002)10.1016/j.neuron.2007.05.020
/ Neuron / Endocannabinoid-mediated long-term plasticity requires cAMP/PKA signaling and RIM1α by Chevaleyre (2007)10.1074/jbc.M100929200
/ J. Biol. Chem. / Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin by Coppola (2001)10.1038/sj.emboj.7600753
/ EMBO J. / A Munc13/RIM/Rab3 tripartite complex: From priming to plasticity? by Dulubova (2005)10.1073/pnas.0806938105
/ Proc. Natl. Acad. Sci. USA / cAMP/PKA signaling and RIM1α mediate presynaptic LTP in the lateral amygdala by Fourcaudot (2008)10.1016/j.neulet.2008.08.026
/ Neurosci. Lett. / Direct interactions between C. elegans RAB-3 and Rim provide a mechanism to target vesicles to the presynaptic density by Gracheva (2008)10.1021/bi702345m
/ Biochemistry / Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes by Guan (2008)10.1016/j.neuron.2010.12.014
/ Neuron / RIM determines Ca2+ channel density and vesicle docking at the presynaptic active zone by Han (2011)10.1016/S0896-6273(02)00667-0
/ Neuron / RIM binding proteins (RBPs) couple Rab3-interacting molecules (RIMs) to voltage-gated Ca(2+) channels by Hibino (2002)10.1016/j.cell.2004.06.029
/ Cell / Calmodulin and Munc13 form a Ca2+ sensor/effector complex that controls short-term synaptic plasticity.). Calmodulin and Munc13 form a Ca2+ sensor/effector complex that controls short-term synaptic plasticity by Junge (2004)10.1523/JNEUROSCI.3235-08.2008
/ J. Neurosci. / RIM1α and RIM1β are synthesized from distinct promoters of the RIM1 gene to mediate differential but overlapping synaptic functions by Kaeser (2008)10.1016/j.neuron.2009.09.019
/ Neuron / ELKS2alpha/CAST deletion selectively increases neurotransmitter release at inhibitory synapses by Kaeser (2009)10.1016/j.cell.2010.12.029
/ Cell / RIM proteins tether Ca2+-channels to presynaptic active zones via a direct PDZ-domain interaction by Kaeser (2011){'year': '1969', 'author': 'Katz', 'series-title': 'The Release of Neural Transmitter Substances', 'key': '10.1016/j.neuron.2011.01.005_bib23'}
/ The Release of Neural Transmitter Substances by Katz (1969)10.1038/nn1904
/ Nat. Neurosci. / RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels by Kiyonaka (2007)10.1074/jbc.M307561200
/ J. Biol. Chem. / Interaction of the ERC family of RIM-binding proteins with the liprin-α family of multidomain proteins by Ko (2003)10.1042/bj3490247
/ Biochem. J. / Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoform by Koch (2000)10.1038/nn732
/ Nat. Neurosci. / A post-docking role for active zone protein Rim by Koushika (2001)10.1371/journal.pbio.0040192
/ PLoS Biol. / Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch by Lu (2006)10.1016/j.cub.2005.10.049
/ Curr. Biol. / UNC-13 interaction with syntaxin is required for synaptic transmission by Madison (2005)10.1016/j.jneumeth.2006.10.009
/ J. Neurosci. Methods / Monitoring synaptic transmission in primary neuronal cultures using local extracellular stimulation by Maximov (2007)10.1126/science.1166505
/ Science / Complexin controls the force transfer from SNARE complexes to membranes in fusion by Maximov (2009)10.1016/j.cell.2007.07.037
/ Cell / Dynamic scaffolding in a G protein-coupled signaling system by Mishra (2007)10.1515/bc.2010.064
/ Biol. Chem. / RIM proteins and their role in synapse function by Mittelstaedt (2010)10.1523/JNEUROSCI.5231-04.2005
/ J. Neurosci. / Reluctant vesicles contribute to the total readily releasable pool in glutamatergic hippocampal neurons by Moulder (2005)10.1083/jcb.200202083
/ J. Cell Biol. / Cast: A novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1 by Ohtsuka (2002)10.1038/nsmb.1843
/ Nat. Struct. Mol. Biol. / Signal integration through blending, bolstering and bifurcating of intracellular information by Pawson (2010)10.1016/S0896-6273(00)80146-4
/ Neuron / Definition of the readily releasable pool of vesicles at hippocampal synapses by Rosenmund (1996)10.1016/S0896-6273(02)00568-8
/ Neuron / Differential control of vesicle priming and short-term plasticity by Munc13 isoforms by Rosenmund (2002)10.1038/415321a
/ Nature / RIM1α forms a protein scaffold for regulating neurotransmitter release at the active zone by Schoch (2002)10.1038/sj.emboj.7601425
/ EMBO J. / Redundant functions of RIM1α and RIM2α in Ca(2+)-triggered neurotransmitter release by Schoch (2006)10.1038/nsmb.1758
/ Nat. Struct. Mol. Biol. / Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis.).Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis by Shin (2010)10.1111/j.1460-9568.2009.06811.x
/ Eur. J. Neurosci. / A common molecular basis for membrane docking and functional priming of synaptic vesicles by Siksou (2009)10.1016/S0896-6273(03)00643-3
/ Neuron / Neurotransmitter release at central synapses by Stevens (2003)10.1016/j.cub.2005.10.055
/ Curr. Biol. / Identification of the minimal protein domain required for priming activity of Munc13-1 by Stevens (2005)10.1146/annurev.neuro.26.041002.131412
/ Annu. Rev. Neurosci. / The synaptic vesicle cycle by Südhof (2004)10.1073/pnas.122623799
/ Proc. Natl. Acad. Sci. USA / Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming by Varoqueaux (2002)10.1016/S0888-7543(02)00024-1
/ Genomics / Genomic definition of RIM proteins: Evolutionary amplification of a family of synaptic regulatory proteins(small star, filled) by Wang (2003)10.1038/41580
/ Nature / Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion by Wang (1997)10.1074/jbc.M909008199
/ J. Biol. Chem. / The RIM/NIM family of neuronal C2 domain proteins. Interactions with Rab3 and a new class of Src homology 3 domain proteins by Wang (2000)10.1073/pnas.182532999
/ Proc. Natl. Acad. Sci. USA / A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones by Wang (2002)10.1523/JNEUROSCI.2350-06.2006
/ J. Neurosci. / UNC-13 and UNC-10/rim localize synaptic vesicles to specific membrane domains by Weimer (2006)10.1016/j.neuron.2007.06.013
/ Neuron / Regulation of membrane fusion in synaptic excitation-secretion coupling: Speed and accuracy matter by Wojcik (2007)10.1016/S0896-6273(01)80039-8
/ Neuron / The reduced release probability of releasable vesicles during recovery from short-term synaptic depression by Wu (1999)10.1523/JNEUROSCI.21-17-06666.2001
/ J. Neurosci. / Three-dimensional comparison of ultrastructural characteristics at depressing and facilitating synapses onto cerebellar Purkinje cells by Xu-Friedman (2001)
Dates
Type | When |
---|---|
Created | 14 years, 7 months ago (Jan. 27, 2011, 4:25 a.m.) |
Deposited | 1 year, 4 months ago (April 22, 2024, 3:27 p.m.) |
Indexed | 3 hours, 57 minutes ago (Aug. 28, 2025, 8:50 a.m.) |
Issued | 14 years, 7 months ago (Jan. 1, 2011) |
Published | 14 years, 7 months ago (Jan. 1, 2011) |
Published Print | 14 years, 7 months ago (Jan. 1, 2011) |
Funders
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National Institutes of Health
10.13039/100000002
Region: Americas
gov (National government)
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- Institutos Nacionales de la Salud
- US National Institutes of Health
- NIH
National Institute of Neurological Disorders and Stroke
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- National Institute of Neurological Disorders & Stroke
- NIH/National Institute of Neurological Disorders and Stroke
- NIH National Institute of Neurological Disorders and Stroke
- Instituto Nacional de Trastornos Neurológicos y Accidentes Cerebrovasculares
- The National Institute of Neurological Disorders and Stroke
- National Institute of Neurological Disorders and Blindness
- National Institute of Neurological and Communicative Disorders and Stroke
- NINDS
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- 33564
- DA029044
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
10.13039/501100001711
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- Schweizerischer Nationalfonds
- Swiss National Science Foundation
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- Fondo Nazionale Svizzero per la Ricerca Scientifica
- Fonds National Suisse
- Fondo Nazionale Svizzero
- Schweizerische Nationalfonds
- SNF
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@article{Deng_2011, title={RIM Proteins Activate Vesicle Priming by Reversing Autoinhibitory Homodimerization of Munc13}, volume={69}, ISSN={0896-6273}, url={http://dx.doi.org/10.1016/j.neuron.2011.01.005}, DOI={10.1016/j.neuron.2011.01.005}, number={2}, journal={Neuron}, publisher={Elsevier BV}, author={Deng, Lunbin and Kaeser, Pascal S. and Xu, Wei and Südhof, Thomas C.}, year={2011}, month=jan, pages={317–331} }