DOI: 10.1016/j.nbd.2006.04.001. Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

10.1016/j.nbd.2006.04.001

Crossref journal-article

Elsevier BV

Neurobiology of Disease (78)

Bibliography

Greggio, E., Jain, S., Kingsbury, A., Bandopadhyay, R., Lewis, P., Kaganovich, A., van der Brug, M. P., Beilina, A., Blackinton, J., Thomas, K. J., Ahmad, R., Miller, D. W., Kesavapany, S., Singleton, A., Lees, A., Harvey, R. J., Harvey, K., & Cookson, M. R. (2006). Kinase activity is required for the toxic effects of mutant LRRK2/dardarin. Neurobiology of Disease, 23(2), 329â341.

Authors 18

Elisa Greggio (first)
Shushant Jain (additional)
Ann Kingsbury (additional)
Rina Bandopadhyay (additional)
Patrick Lewis (additional)
Alice Kaganovich (additional)
Marcel P. van der Brug (additional)
Alexandra Beilina (additional)
Jeff Blackinton (additional)
Kelly Jean Thomas (additional)
Rili Ahmad (additional)
David W. Miller (additional)
Sashi Kesavapany (additional)
Andrew Singleton (additional)
Andrew Lees (additional)
Robert J. Harvey (additional)
Kirsten Harvey (additional)
Mark R. Cookson (additional)

References 28 Referenced 643

10.1016/S0140-6736(05)74810-8 / Lancet / LRRK2 mutations and Parkinsonism by Albrecht (2005)
10.1038/nature02998 / Nature / Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death by Arrasate (2004)
10.1073/pnas.0500617102 / Proc. Natl. Acad. Sci. U. S. A. / Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability by Beilina (2005)
10.1016/j.bbamcr.2003.08.008 / Biochim. Biophys. Acta / Roc, a Ras/GTPase domain in complex proteins by Bosgraaf (2003)
10.1111/j.1471-4159.2005.03099.x / J. Neurochem. / Presenilin function and gamma-secretase activity by Brunkan (2005)
10.1146/annurev.biochem.74.082803.133400 / Annu. Rev. Biochem. / The biochemistry of Parkinson's disease by Cookson (2005)
10.1097/01.wco.0000186841.43505.e6 / Curr. Opin. Neurol. / How genetics research in Parkinson's disease is enhancing understanding of the common idiopathic forms of the disease by Cookson (2005)
10.1242/jcs.00619 / J. Cell Sci. / Intracellular clusterin causes juxtanuclear aggregate formation and mitochondrial alteration by Debure (2003)
10.1002/ana.10113 / Ann. Neurol. / A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2–q13.1 by Funayama (2002)
10.1002/ana.20484 / Ann. Neurol. / An LRRK2 mutation as a cause for the parkinsonism in the original PARK8 family by Funayama (2005)
10.1002/ana.20791 / Ann. Neurol. / Biochemical and pathological characterization of Lrrk2 by Giasson (2006)
10.1093/hmg/ddi439 / Hum. Mol. Genet. / The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity by Gloeckner (2006)
10.1002/ana.20401 / Ann. Neurol. / Clinical and positron emission tomography of Parkinson's disease caused by LRRK2 by Hernandez (2005)
10.1016/j.cellsig.2005.08.015 / Cell Signalling / LRRK1 protein kinase activity is stimulated upon binding of GTP to its Roc domain by Korr (2006)
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Melrose, H., Lincoln, S., Tyndall, G., Dickson, D., Farrer, M., in press. Anatomical localization of leucine-rich repeat kinase 2 in mouse brain. Neuroscience. (Electronic publication ahead of print 2006 Feb. 25). (10.1016/j.neuroscience.2006.01.017)
10.1074/jbc.M304272200 / J. Biol. Chem. / L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin–proteasome system by Miller (2003)
10.1016/j.molcel.2004.08.024 / Mol. Cell / Regulation of protein kinases; controlling activity through activation segment conformation by Nolen (2004)
10.1016/j.neuron.2004.10.023 / Neuron / Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease by Paisan-Ruiz (2004)
10.1136/jmg.2005.036889 / J. Med. Genet. / Testing association between LRRK2 and Parkinson's disease and investigating linkage disequilibrium by Paisan-Ruiz (2006)
10.1016/j.neuron.2004.11.008 / Neuron / Protein kinases linked to the pathogenesis of Parkinson's disease by Shen (2004)
10.1111/j.1460-9568.2006.04616.x / Eur. J. Neurosci. / LRRK2 is expressed in areas affected by Parkinson's disease in the adult mouse brain by Simon-Sanchez (2006)
10.1073/pnas.0508052102 / Proc. Natl. Acad. Sci. U. S. A. / Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration by Smith (2005)
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10.1016/S0140-6736(05)74809-1 / Lancet / LRRK2 mutations and Parkinsonism by Toft (2005)
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10.1016/j.neuron.2004.11.005 / Neuron / Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology by Zimprich (2004)

Dates

Type	When
Created	19 years, 2 months ago (June 6, 2006, 11:34 p.m.)
Deposited	1 year, 6 months ago (Feb. 10, 2024, 1:24 p.m.)
Indexed	1 month ago (July 30, 2025, 9:54 a.m.)
Issued	19 years ago (Aug. 1, 2006)
Published	19 years ago (Aug. 1, 2006)
Published Print	19 years ago (Aug. 1, 2006)

Funders 0

None

BibTeX

@article{Greggio_2006, title={Kinase activity is required for the toxic effects of mutant LRRK2/dardarin}, volume={23}, ISSN={0969-9961}, url={http://dx.doi.org/10.1016/j.nbd.2006.04.001}, DOI={10.1016/j.nbd.2006.04.001}, number={2}, journal={Neurobiology of Disease}, publisher={Elsevier BV}, author={Greggio, Elisa and Jain, Shushant and Kingsbury, Ann and Bandopadhyay, Rina and Lewis, Patrick and Kaganovich, Alice and van der Brug, Marcel P. and Beilina, Alexandra and Blackinton, Jeff and Thomas, Kelly Jean and Ahmad, Rili and Miller, David W. and Kesavapany, Sashi and Singleton, Andrew and Lees, Andrew and Harvey, Robert J. and Harvey, Kirsten and Cookson, Mark R.}, year={2006}, month=aug, pages={329–341} }

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