Crossref
journal-article
Elsevier BV
Molecular Cell (78)
References
79
Referenced
233
10.1371/journal.pone.0013559
/ PLoS ONE / Structural studies of the tandem Tudor domains of fragile X mental retardation related proteins FXR1 and FXR2 by Adams-Cioaba (2010)10.1083/jcb.150.3.447
/ J. Cell Biol. / Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle by Agrawal (2000)10.1097/00005072-199908000-00009
/ J. Neuropathol. Exp. Neurol. / Expression of FMR1, FXR1, and FXR2 genes in human prenatal tissues by Agulhon (1999)10.1038/nature11737
/ Nature / FMRP targets distinct mRNA sequence elements to regulate protein expression by Ascano (2012)10.1126/science.7692601
/ Science / FMR1 protein: conserved RNP family domains and selective RNA binding by Ashley (1993)10.1126/science.1212642
/ Science / The structure of the eukaryotic ribosome at 3.0 Å resolution by Ben-Shem (2011)10.1093/hmg/ddq007
/ Hum. Mol. Genet. / Arginines of the RGG box regulate FMRP association with polyribosomes and mRNA by Blackwell (2010)10.1074/jbc.273.25.15521
/ J. Biol. Chem. / Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein by Brown (1998)10.1016/S0092-8674(01)00568-2
/ Cell / Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome by Brown (2001)10.1093/hmg/ddg350
/ Hum. Mol. Genet. / Phosphorylation influences the translation state of FMRP-associated polyribosomes by Ceman (2003)10.1016/S0306-4522(03)00406-8
/ Neuroscience / The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences by Chen (2003)10.1242/dmm.004598
/ Dis. Model. Mech. / Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P by Coffee (2010)10.1093/hmg/ddr527
/ Hum. Mol. Genet. / In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation by Coffee (2012)10.1073/pnas.94.10.5401
/ Proc. Natl. Acad. Sci. USA / Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits by Comery (1997)10.1093/hmg/6.9.1465
/ Hum. Mol. Genet. / The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes by Corbin (1997)10.1016/S0092-8674(01)00566-9
/ Cell / Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function by Darnell (2001)10.1101/gad.1276805
/ Genes Dev. / Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes by Darnell (2005)10.1016/j.cell.2011.06.013
/ Cell / FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism by Darnell (2011)10.1038/ng0193-31
/ Nat. Genet. / A point mutation in the FMR-1 gene associated with fragile X mental retardation by De Boulle (1993){'key': '10.1016/j.molcel.2014.03.023_bib20', 'first-page': '877', 'article-title': 'Methylation of the arginine-glycine-rich region in the fragile X mental retardation protein FMRP differentially affects RNA binding', 'volume': '7', 'author': 'Denman', 'year': '2002', 'journal-title': 'Cell. Mol. Biol. Lett.'}
/ Cell. Mol. Biol. Lett. / Methylation of the arginine-glycine-rich region in the fragile X mental retardation protein FMRP differentially affects RNA binding by Denman (2002)10.1038/ng0893-335
/ Nat. Genet. / The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation by Devys (1993)10.1242/jcs.02882
/ J. Cell Sci. / Methylation regulates the intracellular protein-protein and protein-RNA interactions of FMRP by Dolzhanskaya (2006)10.1016/S1097-2765(00)80012-X
/ Mol. Cell / FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association by Feng (1997)10.1523/JNEUROSCI.17-05-01539.1997
/ J. Neurosci. / Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes by Feng (1997)10.1006/jsbi.1996.0030
/ J. Struct. Biol. / SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields by Frank (1996)10.1016/S0076-6879(07)29002-0
/ Methods Enzymol. / Studying translational control in Drosophila cell-free systems by Gebauer (2007)10.1038/nprot.2007.452
/ Nat. Protoc. / Preparation of macromolecular complexes for cryo-electron microscopy by Grassucci (2007)10.1073/pnas.141145998
/ Proc. Natl. Acad. Sci. USA / Synaptic regulation of protein synthesis and the fragile X protein by Greenough (2001)10.1136/jmg.2008.059055
/ J. Med. Genet. / The fragile X prevalence paradox by Hagerman (2008)10.1261/rna.7154104
/ RNA / Internal ribosome entry site drives cap-independent translation of reaper and heat shock protein 70 mRNAs in Drosophila embryos by Hernández (2004)10.1038/ng0193-36
/ Nat. Genet. / Tissue specific expression of FMR-1 provides evidence for a functional role in fragile X syndrome by Hinds (1993)10.1002/ajmg.1320410306
/ Am. J. Med. Genet. / Analysis of neocortex in three males with the fragile X syndrome by Hinton (1991)10.1101/gad.1022002
/ Genes Dev. / A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins by Ishizuka (2002)10.1016/j.sbi.2012.07.013
/ Curr. Opin. Struct. Biol. / Crystal structure of the 80S yeast ribosome by Jenner (2012)10.1038/ncb1104-1048
/ Nat. Cell Biol. / RNA and microRNAs in fragile X mental retardation by Jin (2004)10.1038/nn1174
/ Nat. Neurosci. / Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway by Jin (2004)10.1055/s-2001-15401
/ Semin. Reprod. Med. / The female and the fragile X reviewed by Kenneson (2001)10.1038/ng0196-91
/ Nat. Genet. / The fragile X mental retardation protein is associated with ribosomes by Khandjian (1996)10.1093/nar/gkl253
/ Nucleic Acids Res. / QGRS Mapper: a web-based server for predicting G-quadruplexes in nucleotide sequences by Kikin (2006)10.1093/hmg/10.4.329
/ Hum. Mol. Genet. / Evidence that fragile X mental retardation protein is a negative regulator of translation by Laggerbauer (2001)10.1242/dev.00792
/ Development / Control of dendritic development by the Drosophila fragile X-related gene involves the small GTPase Rac1 by Lee (2003)10.1093/nar/29.11.2276
/ Nucleic Acids Res. / The fragile X mental retardation protein inhibits translation via interacting with mRNA by Li (2001)10.1073/pnas.0404995101
/ Proc. Natl. Acad. Sci. USA / The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development by Lu (2004)10.1093/hmg/11.24.3007
/ Hum. Mol. Genet. / Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression by Mazroui (2002)10.1093/hmg/ddg335
/ Hum. Mol. Genet. / Fragile X Mental Retardation protein determinants required for its association with polyribosomal mRNPs by Mazroui (2003)10.1016/S0896-6273(03)00034-5
/ Neuron / RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice by Miyashiro (2003)10.1016/j.molcel.2011.05.006
/ Mol. Cell / Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling by Muddashetty (2011)10.1038/nsb0997-712
/ Nat. Struct. Biol. / The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome by Musco (1997)10.1523/JNEUROSCI.5057-11.2012
/ J. Neurosci. / Dephosphorylation-induced ubiquitination and degradation of FMRP in dendrites: a role in immediate early mGluR-stimulated translation by Nalavadi (2012)10.1523/JNEUROSCI.21-14-05139.2001
/ J. Neurosci. / Abnormal development of dendritic spines in FMR1 knock-out mice by Nimchinsky (2001)10.1146/annurev.neuro.25.112701.142909
/ Annu. Rev. Neurosci. / A decade of molecular studies of fragile X syndrome by O’Donnell (2002)10.1146/annurev.genom.8.080706.092249
/ Annu. Rev. Genomics Hum. Genet. / The pathophysiology of fragile x syndrome by Penagarikano (2007)10.1016/0304-3991(94)90038-8
/ Ultramicroscopy / The ribosome at improved resolution: new techniques for merging and orientation refinement in 3D cryo-electron microscopy of biological particles by Penczek (1994)10.1002/jcc.20084
/ J. Comput. Chem. / UCSF Chimera—a visualization system for exploratory research and analysis by Pettersen (2004)10.1038/nsmb.2064
/ Nat. Struct. Mol. Biol. / Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction by Phan (2011)10.1016/0092-8674(91)90125-I
/ Cell / Absence of expression of the FMR-1 gene in fragile X syndrome by Pieretti (1991)10.1111/j.1742-4658.2004.04527.x
/ FEBS J. / New insights into Fragile X syndrome. Relating genotype to phenotype at the molecular level by Pozdnyakova (2005)10.1016/j.str.2005.09.018
/ Structure / The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction by Ramos (2006)10.1007/BF00687814
/ Acta Neuropathol. / Adult fragile X syndrome. Clinico-neuropathologic findings by Rudelli (1985)10.1093/emboj/20.17.4803
/ EMBO J. / The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif by Schaeffer (2001)10.1038/nprot.2008.156
/ Nat. Protoc. / SPIDER image processing for single-particle reconstruction of biological macromolecules from electron micrographs by Shaikh (2008)10.1016/0092-8674(93)90420-U
/ Cell / The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein by Siomi (1993)10.1016/0092-8674(94)90232-1
/ Cell / Essential role for KH domains in RNA binding: impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome by Siomi (1994)10.1128/MCB.16.7.3825
/ Mol. Cell. Biol. / Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them by Siomi (1996)10.1128/MCB.22.24.8438-8447.2002
/ Mol. Cell. Biol. / Casein kinase II phosphorylates the fragile X mental retardation protein and modulates its biological properties by Siomi (2002)10.1523/JNEUROSCI.2306-04.2004
/ J. Neurosci. / Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells by Stefani (2004)10.1093/hmg/1.6.397
/ Hum. Mol. Genet. / DNA methylation represses FMR-1 transcription in fragile X syndrome by Sutcliffe (1992)10.1093/hmg/5.6.809
/ Hum. Mol. Genet. / FMRP is associated to the ribosomes via RNA by Tamanini (1996)10.1093/emboj/cdf326
/ EMBO J. / Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process by Valle (2002)10.1016/j.str.2007.06.022
/ Structure / Fragile X mental retardation syndrome: structure of the KH1-KH2 domains of fragile X mental retardation protein by Valverde (2007)10.1016/0092-8674(91)90397-H
/ Cell / Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome by Verkerk (1991)10.1093/nar/26.2.655
/ Nucleic Acids Res. / Three-dimensional structure of the yeast ribosome by Verschoor (1998)10.1128/MCB.20.22.8536-8547.2000
/ Mol. Cell. Biol. / Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein by Wan (2000)10.1016/S0092-8674(03)00079-5
/ Cell / The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses by Zalfa (2003)10.1371/journal.pgen.1000758
/ PLoS Genet. / A mouse model of the human Fragile X syndrome I304N mutation by Zang (2009)10.1186/1471-2105-9-40
/ BMC Bioinformatics / I-TASSER server for protein 3D structure prediction by Zhang (2008)10.1002/j.1460-2075.1995.tb00220.x
/ EMBO J. / The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2 by Zhang (1995)10.1016/S0092-8674(01)00589-X
/ Cell / Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function by Zhang (2001)10.1016/j.ydbio.2004.02.010
/ Dev. Biol. / The Drosophila fragile X-related gene regulates axoneme differentiation during spermatogenesis by Zhang (2004)
Dates
Type | When |
---|---|
Created | 11 years, 4 months ago (April 17, 2014, 12:14 p.m.) |
Deposited | 6 years ago (Aug. 9, 2019, 12:55 p.m.) |
Indexed | 1 day, 1 hour ago (Aug. 27, 2025, 11:39 a.m.) |
Issued | 11 years, 3 months ago (May 1, 2014) |
Published | 11 years, 3 months ago (May 1, 2014) |
Published Print | 11 years, 3 months ago (May 1, 2014) |
@article{Chen_2014, title={Fragile X Mental Retardation Protein Regulates Translation by Binding Directly to the Ribosome}, volume={54}, ISSN={1097-2765}, url={http://dx.doi.org/10.1016/j.molcel.2014.03.023}, DOI={10.1016/j.molcel.2014.03.023}, number={3}, journal={Molecular Cell}, publisher={Elsevier BV}, author={Chen, Eileen and Sharma, Manjuli R. and Shi, Xinying and Agrawal, Rajendra K. and Joseph, Simpson}, year={2014}, month=may, pages={407–417} }