DOI: 10.1016/j.molcel.2008.09.019. DAPK-ZIPK-L13a Axis Constitutes a Negative-Feedback Module Regulating Inflammatory Gene Expression

DAPK-ZIPK-L13a Axis Constitutes a Negative-Feedback Module Regulating Inflammatory Gene Expression

10.1016/j.molcel.2008.09.019

Crossref journal-article

Elsevier BV

Molecular Cell (78)

Bibliography

Mukhopadhyay, R., Ray, P. S., Arif, A., Brady, A. K., Kinter, M., & Fox, P. L. (2008). DAPK-ZIPK-L13a Axis Constitutes a Negative-Feedback Module Regulating Inflammatory Gene Expression. Molecular Cell, 32(3), 371â382.

Authors 6

Rupak Mukhopadhyay (first)
Partho Sarothi Ray (additional)
Abul Arif (additional)
Anna K. Brady (additional)
Michael Kinter (additional)
Paul L. Fox (additional)

References 51 Referenced 132

10.1128/MCB.25.17.7605-7615.2005 / Mol. Cell. Biol. / Differential phosphorylation controls Maskin association with eukaryotic translation initiation factor 4E and localization on the mitotic apparatus by Barnard (2005)
10.1146/annurev.biochem.75.103004.142615 / Annu. Rev. Biochem. / The death-associated protein kinases: structure, function, and beyond by Bialik (2006)
10.1016/j.jmb.2003.10.081 / J. Mol. Biol. / Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1 by Burch (2004)
10.1038/sj.emboj.7600510 / EMBO J. / Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK by Chen (2005)
10.1038/nature01322 / Nature / Inflammation and cancer by Coussens (2002)
10.1101/gad.9.1.15 / Genes Dev. / Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the γ interferon-induced cell death by Deiss (1995)
10.1016/S0092-8674(02)00642-6 / Cell / Gene-specific regulation by general translation factors by Dever (2002)
10.1074/jbc.M403676200 / J. Biol. Chem. / Identification and characterization of zipper-interacting protein kinase as the unique vascular smooth muscle myosin phosphatase-associated kinase by Endo (2004)
10.1210/edrv.18.1.0287 / Endocr. Rev. / The biology of vascular endothelial growth factor by Ferrara (1997)
10.1128/MCB.00784-07 / Mol. Cell. Biol. / A critical role for transcription factor C/EBP-β in regulating the expression of death-associated protein kinase-1 by Gade (2008)
10.1038/nrm1488 / Nat. Rev. Mol. Cell Biol. / Molecular mechanisms of translational control by Gebauer (2004)
10.1074/jbc.M412538200 / J. Biol. Chem. / Regulation of zipper-interacting protein kinase activity in vitro and in vivo by multisite phosphorylation by Graves (2005)
10.1093/nar/gkg548 / Nucleic Acids Res. / PatSearch: A program for the detection of patterns and structural motifs in nucleotide sequences by Grillo (2003)
10.1016/j.cellsig.2005.05.008 / Cell. Signal. / ZIP kinase, a key regulator of myosin protein phosphatase 1 by Haystead (2005)
10.1038/36599 / Nature / DAP kinase links the control of apoptosis to metastasis by Inbal (1997)
10.1073/pnas.86.20.7706 / Proc. Natl. Acad. Sci. USA / Improved predictions of secondary structures for RNA by Jaeger (1989)
10.1016/j.molcel.2008.01.010 / Mol. Cell / WHEP domains direct noncanonical function of glutamyl-prolyl tRNA synthetase in translational control of gene expression by Jia (2008)
10.1016/j.molcel.2006.11.028 / Mol. Cell / L13a blocks 48S assembly: Role of a general initiation factor in mRNA-specific translational control by Kapasi (2007)
10.1128/MCB.18.3.1642 / Mol. Cell. Biol. / ZIP kinase, a novel serine/threonine kinase which mediates apoptosis by Kawai (1998)
10.1038/nrg2111 / Nat. Rev. Genet. / RNA regulons: coordination of post-transcriptional events by Keene (2007)
10.1016/S1097-2765(02)00559-2 / Mol. Cell / Eukaryotic mRNPs may represent posttranscriptional operons by Keene (2002)
10.1126/science.273.5282.1717 / Science / Regulation of interferon-γ-activated STAT1 by the ubiquitin-proteasome pathway by Kim (1996)
10.1038/sj.onc.1204302 / Oncogene / Promoter methylation of DAP-kinase: association with advanced stage in non-small cell lung cancer by Kim (2001)
10.1038/sj.onc.1202204 / Oncogene / Cloning and characterization of Dlk, a novel serine/threonine kinase that is tightly associated with chromatin and phosphorylates core histones by Kögel (1998)
10.1038/sj.onc.1203169 / Oncogene / C-terminal truncation of Dlk/ZIP kinase leads to abrogation of nuclear transport and high apoptotic activity by Kögel (1999)
10.1006/cyto.2002.0895 / Cytokine / Transcriptional and post-transcriptional control of gene expression in inflammation by Kracht (2002)
10.1593/neo.06802 / Neoplasia / Early involvement of death-associated protein kinase promoter hypermethylation in the carcinogenesis of Barrett's esophageal adenocarcinoma and its association with clinical progression by Kuester (2007)
10.1073/pnas.0403535101 / Proc. Natl. Acad. Sci. USA / Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family by Li (2004)
10.1093/hmg/ddl178 / Hum. Mol. Genet. / DAPK1 variants are associated with Alzheimer's disease and allele-specific expression by Li (2006)
10.1158/0008-5472.CAN-06-1278 / Cancer Res. / Macrophages regulate the angiogenic switch in a mouse model of breast cancer by Lin (2006)
10.1016/j.tcm.2004.10.004 / Trends Cardiovasc. Med. / Signaling to translational control pathways: diversity in gene regulation in inflammatory and vascular cells by Lindemann (2005)
10.1038/nri2035 / Nat. Rev. Immunol. / MAPK phosphatases—regulating the immune response by Liu (2007)
10.1073/pnas.041331498 / Proc. Natl. Acad. Sci. USA / Identification of the endogenous smooth muscle myosin phosphatase-associated kinase by MacDonald (2001)
10.1182/blood.V99.3.736 / Blood / Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice by Masuoka (2002)
10.1016/S0092-8674(03)00773-6 / Cell / Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control by Mazumder (2003)
10.1016/S0968-0004(03)00002-1 / Trends Biochem. Sci. / Translational control by the 3′-UTR: the ends specify the means by Mazumder (2003)
10.1083/jcb.140.3.627 / J. Cell Biol. / Apoptotic membrane blebbing is regulated by myosin light chain phosphorylation by Mills (1998)
10.1126/science.298.5594.824 / Science / Network motifs: simple building blocks of complex networks by Milo (2002)
10.1038/sj.onc.1205055 / Oncogene / HeLa ZIP kinase induces diphosphorylation of myosin II regulatory light chain and reorganization of actin filaments in nonmuscle cells by Murata-Hori (2001)
10.1128/MCB.22.13.4535-4543.2002 / Mol. Cell. Biol. / c-Src-mediated phosphorylation of hnRNP K drives translational activation of specifically silenced mRNAs by Ostareck-Lederer (2002)
10.1038/sj.emboj.7600193 / EMBO J. / Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases by Raught (2004)
10.1016/j.cell.2007.03.043 / Cell / Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia by Raval (2007)
10.1038/sj.emboj.7601774 / EMBO J. / A post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity by Ray (2007)
10.1128/MCB.23.5.1509-1519.2003 / Mol. Cell. Biol. / Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3′ untranslated region by Sampath (2003)
10.1016/j.cell.2004.09.030 / Cell / Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation by Sampath (2004)
10.1093/intimm/dxh331 / Int. Immunol. / Physical and functional interactions between STAT3 and ZIP kinase by Sato (2005)
10.1128/MCB.24.19.8611-8626.2004 / Mol. Cell. Biol. / Death-associated protein kinase phosphorylates ZIP kinase, forming a unique kinase hierarchy to activate its cell death functions by Shani (2004)
10.1016/j.molcel.2007.11.018 / Mol. Cell / New modes of translational control in development, behavior, and disease by Sonenberg (2007)
10.1128/MCB.16.11.6486 / Mol. Cell. Biol. / A structural basis for substrate specificities of protein Ser/Thr kinases: Primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1 by Songyang (1996)
10.1038/43206 / Nature / A family of cytokine-inducible inhibitors of signalling by Starr (1997)
10.1038/nrm2203 / Nat. Rev. Mol. Cell Biol. / Mechanisms of specificity in protein phosphorylation by Ubersax (2007)

Dates

Type	When
Created	16 years, 9 months ago (Nov. 11, 2008, 3:15 a.m.)
Deposited	6 years, 8 months ago (Dec. 24, 2018, 8:53 a.m.)
Indexed	3 weeks, 3 days ago (Aug. 12, 2025, 6:15 p.m.)
Issued	16 years, 10 months ago (Nov. 1, 2008)
Published	16 years, 10 months ago (Nov. 1, 2008)
Published Print	16 years, 10 months ago (Nov. 1, 2008)

Funders 0

None

BibTeX

@article{Mukhopadhyay_2008, title={DAPK-ZIPK-L13a Axis Constitutes a Negative-Feedback Module Regulating Inflammatory Gene Expression}, volume={32}, ISSN={1097-2765}, url={http://dx.doi.org/10.1016/j.molcel.2008.09.019}, DOI={10.1016/j.molcel.2008.09.019}, number={3}, journal={Molecular Cell}, publisher={Elsevier BV}, author={Mukhopadhyay, Rupak and Ray, Partho Sarothi and Arif, Abul and Brady, Anna K. and Kinter, Michael and Fox, Paul L.}, year={2008}, month=nov, pages={371–382} }

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      "volume": "337",
      "author": "Burch",
      "year": "2004",
      "journal-title": "J. Mol. Biol."
    },
    {
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      "first-page": "294",
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      "article-title": "Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK",
      "volume": "24",
      "author": "Chen",
      "year": "2005",
      "journal-title": "EMBO J."
    },
    {
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      "first-page": "860",
      "DOI": "10.1038/nature01322",
      "article-title": "Inflammation and cancer",
      "volume": "420",
      "author": "Coussens",
      "year": "2002",
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      "first-page": "15",
      "DOI": "10.1101/gad.9.1.15",
      "article-title": "Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the \u03b3 interferon-induced cell death",
      "volume": "9",
      "author": "Deiss",
      "year": "1995",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "545",
      "DOI": "10.1016/S0092-8674(02)00642-6",
      "article-title": "Gene-specific regulation by general translation factors",
      "volume": "108",
      "author": "Dever",
      "year": "2002",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib8",
      "doi-asserted-by": "crossref",
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      "DOI": "10.1074/jbc.M403676200",
      "article-title": "Identification and characterization of zipper-interacting protein kinase as the unique vascular smooth muscle myosin phosphatase-associated kinase",
      "volume": "279",
      "author": "Endo",
      "year": "2004",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "4",
      "DOI": "10.1210/edrv.18.1.0287",
      "article-title": "The biology of vascular endothelial growth factor",
      "volume": "18",
      "author": "Ferrara",
      "year": "1997",
      "journal-title": "Endocr. Rev."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "2528",
      "DOI": "10.1128/MCB.00784-07",
      "article-title": "A critical role for transcription factor C/EBP-\u03b2 in regulating the expression of death-associated protein kinase-1",
      "volume": "28",
      "author": "Gade",
      "year": "2008",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib11",
      "doi-asserted-by": "crossref",
      "first-page": "827",
      "DOI": "10.1038/nrm1488",
      "article-title": "Molecular mechanisms of translational control",
      "volume": "5",
      "author": "Gebauer",
      "year": "2004",
      "journal-title": "Nat. Rev. Mol. Cell Biol."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "9363",
      "DOI": "10.1074/jbc.M412538200",
      "article-title": "Regulation of zipper-interacting protein kinase activity in\u00a0vitro and in\u00a0vivo by multisite phosphorylation",
      "volume": "280",
      "author": "Graves",
      "year": "2005",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "3608",
      "DOI": "10.1093/nar/gkg548",
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      "volume": "31",
      "author": "Grillo",
      "year": "2003",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib14",
      "doi-asserted-by": "crossref",
      "first-page": "1313",
      "DOI": "10.1016/j.cellsig.2005.05.008",
      "article-title": "ZIP kinase, a key regulator of myosin protein phosphatase 1",
      "volume": "17",
      "author": "Haystead",
      "year": "2005",
      "journal-title": "Cell. Signal."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "180",
      "DOI": "10.1038/36599",
      "article-title": "DAP kinase links the control of apoptosis to metastasis",
      "volume": "390",
      "author": "Inbal",
      "year": "1997",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib16",
      "doi-asserted-by": "crossref",
      "first-page": "7706",
      "DOI": "10.1073/pnas.86.20.7706",
      "article-title": "Improved predictions of secondary structures for RNA",
      "volume": "86",
      "author": "Jaeger",
      "year": "1989",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib17",
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      "article-title": "WHEP domains direct noncanonical function of glutamyl-prolyl tRNA synthetase in translational control of gene expression",
      "volume": "29",
      "author": "Jia",
      "year": "2008",
      "journal-title": "Mol. Cell"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "113",
      "DOI": "10.1016/j.molcel.2006.11.028",
      "article-title": "L13a blocks 48S assembly: Role of a general initiation factor in mRNA-specific translational control",
      "volume": "25",
      "author": "Kapasi",
      "year": "2007",
      "journal-title": "Mol. Cell"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "1642",
      "DOI": "10.1128/MCB.18.3.1642",
      "article-title": "ZIP kinase, a novel serine/threonine kinase which mediates apoptosis",
      "volume": "18",
      "author": "Kawai",
      "year": "1998",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "533",
      "DOI": "10.1038/nrg2111",
      "article-title": "RNA regulons: coordination of post-transcriptional events",
      "volume": "8",
      "author": "Keene",
      "year": "2007",
      "journal-title": "Nat. Rev. Genet."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "1161",
      "DOI": "10.1016/S1097-2765(02)00559-2",
      "article-title": "Eukaryotic mRNPs may represent posttranscriptional operons",
      "volume": "9",
      "author": "Keene",
      "year": "2002",
      "journal-title": "Mol. Cell"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib22",
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      "first-page": "1717",
      "DOI": "10.1126/science.273.5282.1717",
      "article-title": "Regulation of interferon-\u03b3-activated STAT1 by the ubiquitin-proteasome pathway",
      "volume": "273",
      "author": "Kim",
      "year": "1996",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "1765",
      "DOI": "10.1038/sj.onc.1204302",
      "article-title": "Promoter methylation of DAP-kinase: association with advanced stage in non-small cell lung cancer",
      "volume": "20",
      "author": "Kim",
      "year": "2001",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "2645",
      "DOI": "10.1038/sj.onc.1202204",
      "article-title": "Cloning and characterization of Dlk, a novel serine/threonine kinase that is tightly associated with chromatin and phosphorylates core histones",
      "volume": "17",
      "author": "K\u00f6gel",
      "year": "1998",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "7212",
      "DOI": "10.1038/sj.onc.1203169",
      "article-title": "C-terminal truncation of Dlk/ZIP kinase leads to abrogation of nuclear transport and high apoptotic activity",
      "volume": "18",
      "author": "K\u00f6gel",
      "year": "1999",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "91",
      "DOI": "10.1006/cyto.2002.0895",
      "article-title": "Transcriptional and post-transcriptional control of gene expression in inflammation",
      "volume": "20",
      "author": "Kracht",
      "year": "2002",
      "journal-title": "Cytokine"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "236",
      "DOI": "10.1593/neo.06802",
      "article-title": "Early involvement of death-associated protein kinase promoter hypermethylation in the carcinogenesis of Barrett's esophageal adenocarcinoma and its association with clinical progression",
      "volume": "9",
      "author": "Kuester",
      "year": "2007",
      "journal-title": "Neoplasia"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "15688",
      "DOI": "10.1073/pnas.0403535101",
      "article-title": "Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family",
      "volume": "101",
      "author": "Li",
      "year": "2004",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "2560",
      "DOI": "10.1093/hmg/ddl178",
      "article-title": "DAPK1 variants are associated with Alzheimer's disease and allele-specific expression",
      "volume": "15",
      "author": "Li",
      "year": "2006",
      "journal-title": "Hum. Mol. Genet."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "11238",
      "DOI": "10.1158/0008-5472.CAN-06-1278",
      "article-title": "Macrophages regulate the angiogenic switch in a mouse model of breast cancer",
      "volume": "66",
      "author": "Lin",
      "year": "2006",
      "journal-title": "Cancer Res."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "9",
      "DOI": "10.1016/j.tcm.2004.10.004",
      "article-title": "Signaling to translational control pathways: diversity in gene regulation in inflammatory and vascular cells",
      "volume": "15",
      "author": "Lindemann",
      "year": "2005",
      "journal-title": "Trends Cardiovasc. Med."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "202",
      "DOI": "10.1038/nri2035",
      "article-title": "MAPK phosphatases\u2014regulating the immune response",
      "volume": "7",
      "author": "Liu",
      "year": "2007",
      "journal-title": "Nat. Rev. Immunol."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "2419",
      "DOI": "10.1073/pnas.041331498",
      "article-title": "Identification of the endogenous smooth muscle myosin phosphatase-associated kinase",
      "volume": "98",
      "author": "MacDonald",
      "year": "2001",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "736",
      "DOI": "10.1182/blood.V99.3.736",
      "article-title": "Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice",
      "volume": "99",
      "author": "Masuoka",
      "year": "2002",
      "journal-title": "Blood"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "187",
      "DOI": "10.1016/S0092-8674(03)00773-6",
      "article-title": "Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control",
      "volume": "115",
      "author": "Mazumder",
      "year": "2003",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "91",
      "DOI": "10.1016/S0968-0004(03)00002-1",
      "article-title": "Translational control by the 3\u2032-UTR: the ends specify the means",
      "volume": "28",
      "author": "Mazumder",
      "year": "2003",
      "journal-title": "Trends Biochem. Sci."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib37",
      "doi-asserted-by": "crossref",
      "first-page": "627",
      "DOI": "10.1083/jcb.140.3.627",
      "article-title": "Apoptotic membrane blebbing is regulated by myosin light chain phosphorylation",
      "volume": "140",
      "author": "Mills",
      "year": "1998",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib38",
      "doi-asserted-by": "crossref",
      "first-page": "824",
      "DOI": "10.1126/science.298.5594.824",
      "article-title": "Network motifs: simple building blocks of complex networks",
      "volume": "298",
      "author": "Milo",
      "year": "2002",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib39",
      "doi-asserted-by": "crossref",
      "first-page": "8175",
      "DOI": "10.1038/sj.onc.1205055",
      "article-title": "HeLa ZIP kinase induces diphosphorylation of myosin II regulatory light chain and reorganization of actin filaments in nonmuscle cells",
      "volume": "20",
      "author": "Murata-Hori",
      "year": "2001",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib40",
      "doi-asserted-by": "crossref",
      "first-page": "4535",
      "DOI": "10.1128/MCB.22.13.4535-4543.2002",
      "article-title": "c-Src-mediated phosphorylation of hnRNP K drives translational activation of specifically silenced mRNAs",
      "volume": "22",
      "author": "Ostareck-Lederer",
      "year": "2002",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib41",
      "doi-asserted-by": "crossref",
      "first-page": "1761",
      "DOI": "10.1038/sj.emboj.7600193",
      "article-title": "Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases",
      "volume": "23",
      "author": "Raught",
      "year": "2004",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib42",
      "doi-asserted-by": "crossref",
      "first-page": "879",
      "DOI": "10.1016/j.cell.2007.03.043",
      "article-title": "Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia",
      "volume": "129",
      "author": "Raval",
      "year": "2007",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib43",
      "doi-asserted-by": "crossref",
      "first-page": "3360",
      "DOI": "10.1038/sj.emboj.7601774",
      "article-title": "A post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity",
      "volume": "26",
      "author": "Ray",
      "year": "2007",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib44",
      "doi-asserted-by": "crossref",
      "first-page": "1509",
      "DOI": "10.1128/MCB.23.5.1509-1519.2003",
      "article-title": "Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3\u2032 untranslated region",
      "volume": "23",
      "author": "Sampath",
      "year": "2003",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib45",
      "doi-asserted-by": "crossref",
      "first-page": "195",
      "DOI": "10.1016/j.cell.2004.09.030",
      "article-title": "Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation",
      "volume": "119",
      "author": "Sampath",
      "year": "2004",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib46",
      "doi-asserted-by": "crossref",
      "first-page": "1543",
      "DOI": "10.1093/intimm/dxh331",
      "article-title": "Physical and functional interactions between STAT3 and ZIP kinase",
      "volume": "17",
      "author": "Sato",
      "year": "2005",
      "journal-title": "Int. Immunol."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib47",
      "doi-asserted-by": "crossref",
      "first-page": "8611",
      "DOI": "10.1128/MCB.24.19.8611-8626.2004",
      "article-title": "Death-associated protein kinase phosphorylates ZIP kinase, forming a unique kinase hierarchy to activate its cell death functions",
      "volume": "24",
      "author": "Shani",
      "year": "2004",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib48",
      "doi-asserted-by": "crossref",
      "first-page": "721",
      "DOI": "10.1016/j.molcel.2007.11.018",
      "article-title": "New modes of translational control in development, behavior, and disease",
      "volume": "28",
      "author": "Sonenberg",
      "year": "2007",
      "journal-title": "Mol. Cell"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib49",
      "doi-asserted-by": "crossref",
      "first-page": "6486",
      "DOI": "10.1128/MCB.16.11.6486",
      "article-title": "A structural basis for substrate specificities of protein Ser/Thr kinases: Primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1",
      "volume": "16",
      "author": "Songyang",
      "year": "1996",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib50",
      "doi-asserted-by": "crossref",
      "first-page": "917",
      "DOI": "10.1038/43206",
      "article-title": "A family of cytokine-inducible inhibitors of signalling",
      "volume": "387",
      "author": "Starr",
      "year": "1997",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.molcel.2008.09.019_bib51",
      "doi-asserted-by": "crossref",
      "first-page": "530",
      "DOI": "10.1038/nrm2203",
      "article-title": "Mechanisms of specificity in protein phosphorylation",
      "volume": "8",
      "author": "Ubersax",
      "year": "2007",
      "journal-title": "Nat. Rev. Mol. Cell Biol."
    }
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