Crossref journal-article
Elsevier BV
Journal of Molecular Biology (78)
Bibliography

Beskow, A., Grimberg, K. B., Bott, L. C., Salomons, F. A., Dantuma, N. P., & Young, P. (2009). A Conserved Unfoldase Activity for the p97 AAA-ATPase in Proteasomal Degradation. Journal of Molecular Biology, 394(4), 732–746.

Authors 6
  1. Anne Beskow (first)
  2. Kristian Björk Grimberg (additional)
  3. Laura C. Bott (additional)
  4. Florian A. Salomons (additional)
  5. Nico P. Dantuma (additional)
  6. Patrick Young (additional)
References 63 Referenced 109
  1. 10.1016/S1097-2765(01)00347-1 / Mol. Cell / Ubiquitin enters the new millennium by Pickart (2001)
  2. 10.1152/physrev.00027.2001 / Physiol. Rev. / The ubiquitin–proteasome proteolytic pathway: destruction for the sake of construction by Glickman (2002)
  3. 10.1091/mbc.e07-10-1040 / Mol. Biol. Cell / Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome by Koulich (2008)
  4. 10.1038/80992 / Nat. Struct. Biol. / A gated channel into the proteasome core particle by Groll (2000)
  5. 10.1016/j.molcel.2008.03.004 / Mol. Cell / Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases by Rabl (2008)
  6. 10.1074/jbc.270.14.8172 / J. Biol. Chem. / Methotrexate inhibits proteolysis of dihydrofolate reductase by the N-end rule pathway by Johnston (1995)
  7. 10.1021/ja072027p / J. Am. Chem. Soc. / Identification of a peptoid inhibitor of the proteasome 19S regulatory particle by Lim (2007)
  8. 10.1038/nsmb.1427 / Nat. Struct. Mol. Biol. / The central unit within the 19S regulatory particle of the proteasome by Rosenzweig (2008)
  9. 10.1016/S1097-2765(01)00407-5 / Mol. Cell / Proteins are unfolded on the surface of the ATPase ring before transport into the proteasome by Navon (2001)
  10. 10.1002/j.1460-2075.1990.tb08300.x / EMBO J. / An abundant and ubiquitous homo-oligomeric ring-shaped ATPase particle related to the putative vesicle fusion proteins Sec18p and NSF by Peters (1990)
  11. 10.1016/j.molcel.2006.03.036 / Mol. Cell / Central pore residues mediate the p97/VCP activity required for ERAD by DeLaBarre (2006)
  12. 10.1016/j.jmb.2005.01.060 / J. Mol. Biol. / Nucleotide dependent motion and mechanism of action of p97/VCP by DeLaBarre (2005)
  13. 10.1016/j.str.2008.02.010 / Structure / Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change by Davies (2008)
  14. 10.1016/S1074-7613(00)80145-4 / Immunity / Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis by Shirogane (1999)
  15. 10.1038/ncb1201-1086 / Nat. Cell Biol. / Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly by Hetzer (2001)
  16. 10.1016/S0092-8674(00)81128-9 / Cell / Syntaxin 5 is a common component of the NSF- and p97-mediated reassembly pathways of Golgi cisternae from mitotic Golgi fragments in vitro by Rabouille (1998)
  17. 10.1091/mbc.11.8.2529 / Mol. Biol. Cell / Role of p97 and syntaxin 5 in the assembly of transitional endoplasmic reticulum by Roy (2000)
  18. 10.1074/jbc.M805517200 / J. Biol. Chem. / Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP associated disease by Ju (2008)
  19. {'key': '10.1016/j.jmb.2009.09.050_bib19', 'first-page': '95', 'article-title': 'The role of p97/Cdc48p in endoplasmic reticulum-associated degradation: from the immune system to yeast', 'volume': '300', 'author': 'Bar-Nun', 'year': '2005', 'journal-title': 'Curr. Top. Microbiol. Immunol.'} / Curr. Top. Microbiol. Immunol. / The role of p97/Cdc48p in endoplasmic reticulum-associated degradation: from the immune system to yeast by Bar-Nun (2005)
  20. 10.1016/j.cell.2004.11.013 / Cell / A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting by Richly (2005)
  21. 10.1091/mbc.e06-05-0432 / Mol. Biol. Cell / Valosin-containing protein (p97) is a regulator of endoplasmic reticulum stress and of the degradation of N-end rule and ubiquitin-fusion degradation pathway substrates in mammalian cells by Wojcik (2006)
  22. 10.1038/ncb1554 / Nat. Cell Biol. / The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy by Janiesch (2007)
  23. 10.1038/nature06388 / Nature / Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin by Ramadan (2007)
  24. 10.1093/emboj/19.10.2181 / EMBO J. / A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways by Meyer (2000)
  25. 10.1038/ncb0805-742 / Nat. Cell Biol. / Delivery of ubiquitinated substrates to protein-unfolding machines by Elsasser (2005)
  26. 10.1074/jbc.273.6.3562 / J. Biol. Chem. / Involvement of valosin-containing protein, an ATPase Co-purified with IkappaBalpha and 26 S proteasome, in ubiquitin–proteasome-mediated degradation of IkappaBalpha by Dai (1998)
  27. 10.1016/j.cell.2008.06.048 / Cell / UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover by Alexandru (2008)
  28. 10.1021/bi802198q / Biochemistry / Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins by Besche (2009)
  29. 10.1038/35087056 / Nat. Cell Biol. / Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin–proteasome degradation by Dai (2001)
  30. 10.1016/S0092-8674(03)00815-8 / Cell / The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis by Cao (2003)
  31. 10.1083/jcb.200307025 / J. Cell Biol. / Cdc48p is required for the cell cycle commitment point at Start via degradation of the G1-CDK inhibitor Far1p by Fu (2003)
  32. 10.1128/MCB.25.11.4662-4675.2005 / Mol. Cell. Biol. / Identification and characterization of a Drosophila proteasome regulatory network by Lundgren (2005)
  33. 10.1093/emboj/19.1.94 / EMBO J. / Recognition of the polyubiquitin proteolytic signal by Thrower (2000)
  34. 10.1074/jbc.M207783200 / J. Biol. Chem. / Functional ATPase activity of p97/valosin-containing protein (VCP) is required for the quality control of endoplasmic reticulum in neuronally differentiated mammalian PC12 cells by Kobayashi (2002)
  35. 10.1074/jbc.M208422200 / J. Biol. Chem. / ATPase activity of p97-valosin-containing protein (VCP). D2 mediates the major enzyme activity, and D1 contributes to the heat-induced activity by Song (2003)
  36. 10.1016/S0006-291X(02)02840-1 / Biochem. Biophys. Res. Commun. / Hexamerization of p97-VCP is promoted by ATP binding to the D1 domain and required for ATPase and biological activities by Wang (2003)
  37. 10.1073/pnas.95.11.5857 / Proc. Natl Acad. Sci. USA / SMART, a simple modular architecture research tool: identification of signaling domains by Schultz (1998)
  38. 10.1083/jcb.200302169 / J. Cell Biol. / Function of the p97–Ufd1–Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains by Ye (2003)
  39. 10.1074/jbc.M402954200 / J. Biol. Chem. / Localization to the proteasome is sufficient for degradation by Janse (2004)
  40. 10.1038/nsmb814 / Nat. Struct. Mol. Biol. / An unstructured initiation site is required for efficient proteasome-mediated degradation by Prakash (2004)
  41. 10.1002/prot.20730 / Proteins / SAM-T04: what is new in protein-structure prediction for CASP6 by Karplus (2005)
  42. 10.1016/j.jmb.2005.04.031 / J. Mol. Biol. / Extended and flexible domain solution structure of the extracellular matrix protein anosmin-1 by X-ray scattering, analytical ultracentrifugation and constrained modelling by Hu (2005)
  43. 10.1038/sj.emboj.7600165 / EMBO J. / Structure of a kinesin microtubule depolymerization machine by Shipley (2004)
  44. 10.1038/sj.emboj.7601476 / EMBO J. / Proteasome substrate degradation requires association plus extended peptide by Takeuchi (2007)
  45. 10.1096/fj.08-115055 / FASEB J. / Minimal length requirement for proteasomal degradation of ubiquitin-dependent substrates by Verhoef (2009)
  46. 10.1074/jbc.270.29.17442 / J. Biol. Chem. / A proteolytic pathway that recognizes ubiquitin as a degradation signal by Johnson (1995)
  47. 10.1128/MCB.19.5.3664 / Mol. Cell. Biol. / Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain by Orian (1999)
  48. 10.1016/j.tibs.2004.09.011 / Trends Biochem. Sci. / Protein unfolding in the cell by Prakash (2004)
  49. 10.1038/nm1066 / Nat. Med. / Protein aggregation and neurodegenerative disease by Ross (2004)
  50. 10.1016/S0140-6736(97)08360-8 / Lancet / Are neuronal intranuclear inclusions the common neuropathology of triplet-repeat disorders with polyglutamine-repeat expansions? by Davies (1998)
  51. 10.1016/S1097-2765(04)00151-0 / Mol. Cell / Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins by Venkatraman (2004)
  52. 10.1038/sj.emboj.7600426 / EMBO J. / Inefficient degradation of truncated polyglutamine proteins by the proteasome by Holmberg (2004)
  53. 10.1002/jnr.22052 / J. Neurosci. Res. / Biochemical analysis of oligomerization of expanded polyalanine repeat proteins by Nojima (2009)
  54. 10.1016/j.gde.2005.04.003 / Curr. Opin. Genet. Dev. / The other trinucleotide repeat: polyalanine expansion disorders by Albrecht (2005)
  55. 10.1093/emboj/21.4.615 / EMBO J. / Role of the ubiquitin-selective CDC48(Ufd1/Npl4) chaperone (segregase) in ERAD of OLE1 and other substrates by Braun (2002)
  56. 10.1016/j.tibs.2006.11.005 / Trends Biochem. Sci. / Cdc48 (p97): a “molecular gearbox” in the ubiquitin pathway? by Jentsch (2007)
  57. 10.1073/pnas.0810611105 / Proc. Natl Acad. Sci. USA / Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes by Kim (2008)
  58. 10.1074/jbc.M806269200 / J. Biol. Chem. / Single neuron ubiquitin–proteasome dynamics accompanying inclusion body formation in Huntington disease by Mitra (2009)
  59. 10.1126/science.1079293 / Science / Endoproteolytic activity of the proteasome by Liu (2003)
  60. 10.1038/nsmb1122 / Nat. Struct. Mol. Biol. / Proteasome-mediated protein processing by bidirectional degradation initiated from an internal site by Piwko (2006)
  61. 10.1038/75406 / Nat. Biotechnol. / Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells by Dantuma (2000)
  62. 10.1110/ps.0366103 / Protein Sci. / Fast protein folding on downhill energy landscape by Cavalli (2003)
  63. 10.1083/jcb.200202032 / J. Cell Biol. / Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle by Rogers (2002)
Dates
Type When
Created 15 years, 10 months ago (Sept. 25, 2009, 11:47 a.m.)
Deposited 3 years, 2 months ago (June 16, 2022, 1:39 a.m.)
Indexed 1 month, 1 week ago (July 8, 2025, 6:44 a.m.)
Issued 15 years, 8 months ago (Dec. 1, 2009)
Published 15 years, 8 months ago (Dec. 1, 2009)
Published Print 15 years, 8 months ago (Dec. 1, 2009)
Funders 6
  1. Swedish Research Council, the Swedish Cancer Society
  2. Nordic Center of Excellence Neurodegeneration
  3. EU Center of Excellence Rubicon
  4. the Marie Curie Research Training Network
    Awards1
    1. MRTN-CT-2004-512585
  5. Karolinska Institute 10.13039/501100004047 Karolinska Institutet

    Region: Europe

    gov (Local government)

    Labels2
    1. Karolinska Institute
    2. KI
  6. Swedish Research Council 10.13039/501100004359 Vetenskapsrådet

    Region: Europe

    gov (National government)

    Labels2
    1. Swedish Research Council
    2. VR

@article{Beskow_2009, title={A Conserved Unfoldase Activity for the p97 AAA-ATPase in Proteasomal Degradation}, volume={394}, ISSN={0022-2836}, url={http://dx.doi.org/10.1016/j.jmb.2009.09.050}, DOI={10.1016/j.jmb.2009.09.050}, number={4}, journal={Journal of Molecular Biology}, publisher={Elsevier BV}, author={Beskow, Anne and Grimberg, Kristian Björk and Bott, Laura C. and Salomons, Florian A. and Dantuma, Nico P. and Young, Patrick}, year={2009}, month=dec, pages={732–746} }