DOI: 10.1016/j.ijpharm.2006.08.039. Effect of transferrin receptor-targeted liposomal doxorubicin in P-glycoprotein-mediated drug resistant tumor cells

Effect of transferrin receptor-targeted liposomal doxorubicin in P-glycoprotein-mediated drug resistant tumor cells

10.1016/j.ijpharm.2006.08.039

Crossref journal-article

Elsevier BV

International Journal of Pharmaceutics (78)

Bibliography

Kobayashi, T., Ishida, T., Okada, Y., Ise, S., Harashima, H., & Kiwada, H. (2007). Effect of transferrin receptor-targeted liposomal doxorubicin in P-glycoprotein-mediated drug resistant tumor cells. International Journal of Pharmaceutics, 329(1â2), 94â102.

Authors 6

Tomotaka Kobayashi (first)
Tatsuhiro Ishida (additional)
Yurie Okada (additional)
Saori Ise (additional)
Hideyoshi Harashima (additional)
Hiroshi Kiwada (additional)

References 55 Referenced 136

{'key': '10.1016/j.ijpharm.2006.08.039_bib1', 'first-page': '539', 'article-title': 'Effect of liposome size and drug release properties on pharmacokinetics of encapsulated drug in rats', 'volume': '226', 'author': 'Allen', 'year': '1983', 'journal-title': 'J. Pharmacol. Exp. Ther.'} / J. Pharmacol. Exp. Ther. / Effect of liposome size and drug release properties on pharmacokinetics of encapsulated drug in rats by Allen (1983)
10.1016/0005-2736(91)90246-5 / Biochim. Biophys. Acta / Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo by Allen (1991)
10.1016/0165-6147(94)90314-X / Trends Pharmacol. Sci. / Long-circulating (sterically stabilized) liposomes for targeted drug delivery by Allen (1994)
10.1158/1078-0432.CCR-04-2517 / Clin. Cancer Res. / Anti-CD19-targeted liposomal doxorubicin improves the therapeutic efficacy in murine B-cell lymphoma and ameliorates the toxicity of liposomes with varying drug release rates by Allen (2005)
10.1016/S0021-9258(18)70226-3 / J. Biol. Chem. / Phosphorus assay in column chromatography by Bartlett (1959)
{'key': '10.1016/j.ijpharm.2006.08.039_bib6', 'first-page': '3', 'article-title': 'Mechanisms of drug resistance in hematologic malignancies', 'volume': '34', 'author': 'Dalton', 'year': '1997', 'journal-title': 'Semin. Hematol.'} / Semin. Hematol. / Mechanisms of drug resistance in hematologic malignancies by Dalton (1997)
{'key': '10.1016/j.ijpharm.2006.08.039_bib7', 'first-page': '23', 'article-title': 'Drug resistance in multiple myeloma: approaches to circumvention', 'volume': '26', 'author': 'Dalton', 'year': '1999', 'journal-title': 'Semin. Oncol.'} / Semin. Oncol. / Drug resistance in multiple myeloma: approaches to circumvention by Dalton (1999)
10.3109/10428199709059682 / Leuk. Lymphoma / P-glycoprotein expression in de novo acute myeloid leukemia by Del Poeta (1997)
10.1093/jnci/djh314 / J. Natl. Cancer Inst. / Transferrin-conjugated liposome targeting of photosensitizer AlPcS4 to rat bladder carcinoma cells by Derycke (2004)
10.1111/j.1749-6632.1993.tb17204.x / Ann. NY Acad. Sci. / Breast carcinoma and the role of iron metabolism. A cytochemical, tissue culture, and ultrastructural study by Elliott (1993)
{'key': '10.1016/j.ijpharm.2006.08.039_bib11', 'first-page': '2066', 'article-title': 'Fluorescence imaging studies for the disposition of daunorubicin liposomes (DaunoXome) within tumor tissue', 'volume': '56', 'author': 'Forssen', 'year': '1996', 'journal-title': 'Cancer Res.'} / Cancer Res. / Fluorescence imaging studies for the disposition of daunorubicin liposomes (DaunoXome) within tumor tissue by Forssen (1996)
{'key': '10.1016/j.ijpharm.2006.08.039_bib12', 'first-page': '891', 'article-title': 'Selective tumor localization and improved therapeutic index of anthracyclines encapsulated in long-circulating liposomes', 'volume': '52', 'author': 'Gabizon', 'year': '1992', 'journal-title': 'Cancer Res.'} / Cancer Res. / Selective tumor localization and improved therapeutic index of anthracyclines encapsulated in long-circulating liposomes by Gabizon (1992)
10.1002/ijc.10548 / Int. J. Cancer / Targeting of the photocytotoxic compound AlPcS4 to Hela cells by transferrin conjugated PEG-liposomes by Gijsens (2002)
10.3109/10428199609054866 / Leuk. Lymphoma / Multifactorial drug-resistance phenomenon in acute leukemias: impact of P170-MDR1, LRP56 protein, glutathione-transferases and metallothionein systems on clinical outcome by Goasguen (1996)
10.1038/bjc.1996.193 / Brit. J. Cancer / Efficacy and safety of Stealth liposomal doxorubicin in AIDS-related Kaposi's sarcoma. The international SL-DOX study group by Goebel (1996)
{'key': '10.1016/j.ijpharm.2006.08.039_bib16', 'first-page': '1949', 'article-title': 'Nuclear delivery of doxorubicin via Folate-targeted liposomes with bypass of multidrug-resistance efflux pump', 'volume': '6', 'author': 'Goren', 'year': '2000', 'journal-title': 'Clin. Cancer Res.'} / Clin. Cancer Res. / Nuclear delivery of doxorubicin via Folate-targeted liposomes with bypass of multidrug-resistance efflux pump by Goren (2000)
10.1146/annurev.bi.62.070193.002125 / Annu. Rev. Biochem. / Biochemistry of multidrug resistance mediated by the multidrug transporter by Gottesman (1993)
10.1016/S0021-9258(19)57324-0 / J. Biol. Chem. / Purification of the 170 to 180-kilodalton membrane glycoprotein associated with multidrug resistance. 170 to 180-kilodalton membrane glycoprotein is an ATPase by Hamada (1988)
10.1016/0005-2736(93)90105-9 / Biochim. Biophys. Acta / Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases by Haran (1993)
10.1016/0009-3084(75)90037-7 / Chem. Phys. Lipids / Permeability and integrity properties of lecithin-sphingomyelin liposomes by Hertz (1975)
10.1152/physrev.1987.67.2.520 / Physiol. Rev. / The physiology of transferrin and transferrin receptors by Huebers (1987)
10.1002/ijc.10242 / Int. J. Cancer / Intracellular targeting therapy of cisplatin-encapsulated transferrin-polyethylene glycol liposome on peritoneal dissemination of gastric cancer by Iinuma (2002)
10.1023/A:1010960900254 / Pharm. Res. / Liposomes bearing polyethyleneglycol-coupled transferrin with intracellular targeting property to the solid tumors in vivo by Ishida (2001)
10.1016/S0005-2736(01)00409-6 / Biochim. Biophys. Acta / Targeted delivery and triggered release of liposomal doxorubicin enhances cytotoxicity against human B lymphoma cells by Ishida (2001)
10.1016/j.jconrel.2003.12.011 / J. Control. Release / Effect of the physicochemical properties of initially injected liposomes on the clearance of subsequently injected PEGylated liposomes in mice by Ishida (2004)
10.1016/0014-5793(96)00521-2 / FEBS Lett. / Liposomes with detachable polymer coating: destabilization and fusion of dioleoylphosphatidylethanolamine vesicles triggered by cleavage of surface-grafted poly(ethylene glycol) by Kirpotin (1996)
{'key': '10.1016/j.ijpharm.2006.08.039_bib27', 'first-page': '3320', 'article-title': 'In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma', 'volume': '58', 'author': 'Lopes de Menezes', 'year': '1998', 'journal-title': 'Cancer Res.'} / Cancer Res. / In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma by Lopes de Menezes (1998)
10.1016/S1368-7646(03)00082-7 / Drug Resist. Updat. / Liposome-based approaches to overcome anticancer drug resistance by Mamot (2003)
{'key': '10.1016/j.ijpharm.2006.08.039_bib29', 'first-page': '825', 'article-title': 'Daunorubicin uptake by leukemic cells: correlations with treatment outcome and MDR1 expression', 'volume': '7', 'author': 'Marie', 'year': '1993', 'journal-title': 'Leukemia'} / Leukemia / Daunorubicin uptake by leukemic cells: correlations with treatment outcome and MDR1 expression by Marie (1993)
10.1002/jps.2600791107 / J. Pharm. Sci. / Characterization of in vivo immunoliposome targeting to pulmonary endothelium by Maruyama (1990)
10.1016/S0168-3659(01)00460-6 / J. Control. Release / Possibility of the reversal of multidrug resistance and the avoidance of side effects by liposomes modified with MRK-16, a monoclonal antibody to P-glycoprotein by Matsuo (2001)
10.1038/bjc.1995.98 / Brit. J. Cancer / Pharmacology of liposomal vincristine in mice bearing L1210 ascitic and B16/BL6 solid tumours by Mayer (1995)
10.1016/0022-1759(83)90303-4 / J. Immunol. Meth. / Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays by Mosmann (1983)
10.1248/bpb.17.935 / Biol. Pharm. Bull. / Effects of fluidity and vesicle size on antitumor activity and myelosuppressive activity of liposomes loaded with daunorubicin by Nagayasu (1994)
10.1007/BF00685532 / Cancer Chemother. Pharmacol. / Sensitization of multidrug-resistant colon cancer cells to doxorubicin encapsulated in liposomes by Oudard (1991)
10.1002/(SICI)1097-0215(19990412)81:2<268::AID-IJC17>3.0.CO;2-1 / Int. J. Cancer / GD2-mediated melanoma cell targeting and cytotoxicity of liposome-entrapped fenretinide by Pagnan (1999)
{'key': '10.1016/j.ijpharm.2006.08.039_bib37', 'first-page': '219', 'article-title': 'Therapeutic efficacy of a new topoisomerase I and II inhibitor TAS-103, against both P-glycoprotein-expressing and -nonexpressing drug-resistant human small-cell lung cancer', 'volume': '11', 'author': 'Parajuli', 'year': '1999', 'journal-title': 'Oncol. Res.'} / Oncol. Res. / Therapeutic efficacy of a new topoisomerase I and II inhibitor TAS-103, against both P-glycoprotein-expressing and -nonexpressing drug-resistant human small-cell lung cancer by Parajuli (1999)
{'key': '10.1016/j.ijpharm.2006.08.039_bib38', 'first-page': '1172', 'article-title': 'Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery', 'volume': '8', 'author': 'Park', 'year': '2002', 'journal-title': 'Clin. Cancer Res.'} / Clin. Cancer Res. / Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery by Park (2002)
10.1124/pr.54.4.561 / Pharmacol. Rev. / Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway by Qian (2002)
10.1093/jnci/84.24.1909 / J. Natl. Cancer Inst. / Liposome-mediated modulation of multidrug resistance in human HL-60 leukemia cells by Rahman (1992)
10.1016/S0006-2952(97)00326-2 / Biochem. Pharmacol. / Flip-flop of doxorubicin across erythrocyte and lipid membranes by Regev (1997)
10.1074/jbc.M101786200 / J. Biol. Chem. / Determination of the upper size limit for uptake and processing of ligands by the asialoglycoprotein receptor on hepatocytes in vitro and in vivo by Rensen (2001)
10.1038/316817a0 / Nature / Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines by Riordan (1985)
10.1007/s00280-001-0405-3 / Cancer Chemother. Pharmacol. / Lack of activity of stealth liposomal doxorubicin in the treatment of patients with anthracycline-resistant breast cancer by Rivera (2002)
{'key': '10.1016/j.ijpharm.2006.08.039_bib45', 'first-page': '7190', 'article-title': 'Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs', 'volume': '62', 'author': 'Sapra', 'year': '2002', 'journal-title': 'Cancer Res.'} / Cancer Res. / Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs by Sapra (2002)
{'key': '10.1016/j.ijpharm.2006.08.039_bib46', 'first-page': '1545', 'article-title': 'Membrane transport proteins associated with drug resistance expressed in human melanoma', 'volume': '147', 'author': 'Schadendorf', 'year': '1995', 'journal-title': 'Am. J. Pathol.'} / Am. J. Pathol. / Membrane transport proteins associated with drug resistance expressed in human melanoma by Schadendorf (1995)
10.1007/s002800050849 / Cancer Chemother. Pharmacol. / Circumvention of multidrug resistance by a quinoline derivative, MS-209, in multidrug-resistant human small-cell lung cancer cells and its synergistic interaction with cyclosporin A or verapamil by Shrivastava (1998)
10.2174/138161280506230110111312 / Curr. Pharm. Des. / Transferrin as a targeting ligand for liposomes and anticancer drugs by Singh (1999)
{'key': '10.1016/j.ijpharm.2006.08.039_bib49', 'first-page': '3221', 'article-title': 'Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines', 'volume': '53', 'author': 'Slovak', 'year': '1993', 'journal-title': 'Cancer Res.'} / Cancer Res. / Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines by Slovak (1993)
10.1016/0006-2952(91)90531-9 / Biochem. Pharmacol. / P-glycoprotein drug efflux pump involved in the mechanisms of intrinsic drug resistance in various colon cancer cell lines. Evidence for a saturation of active daunorubicin transport by Spoelstra (1991)
10.1016/0006-291X(92)91310-M / Biochem. Biophys Res. Commun. / Effect of liposomes on P-glycoprotein function in multidrug resistant cells by Thierry (1992)
10.1096/fasebj.7.6.8097173 / FASEB J. / Modulation of doxorubicin resistance in multidrug-resistant cells by liposomes by Thierry (1993)
10.1073/pnas.84.9.3004 / Proc. Natl. Acad. Sci. U.S.A. / Expression of a full-length cDNA for the human “MDR1” gene confers resistance to colchicine, doxorubicin, and vinblastine by Ueda (1987)
{'key': '10.1016/j.ijpharm.2006.08.039_bib54', 'first-page': '3241', 'article-title': 'Increased accumulation of drugs in multidrug-resistant cells induced by liposomes', 'volume': '52', 'author': 'Warren', 'year': '1992', 'journal-title': 'Cancer Res.'} / Cancer Res. / Increased accumulation of drugs in multidrug-resistant cells induced by liposomes by Warren (1992)
10.1089/10430349950016357 / Hum. Gene. Ther. / Transferrin-liposome-mediated systemic p53 gene therapy in combination with radiation results in regression of human head and neck cancer xenografts by Xu (1999)

Dates

Type	When
Created	18 years, 11 months ago (Sept. 2, 2006, 7:22 a.m.)
Deposited	1 year, 6 months ago (Feb. 6, 2024, 3:41 a.m.)
Indexed	6 months, 1 week ago (Feb. 20, 2025, 10:52 p.m.)
Issued	18 years, 7 months ago (Feb. 1, 2007)
Published	18 years, 7 months ago (Feb. 1, 2007)
Published Print	18 years, 7 months ago (Feb. 1, 2007)

Funders 2

Ministry of Education, Culture, Sports, Science and Technology 10.13039/501100001700
Region: Asia
gov (National government)
Labels3
1. Monbu-kagaku-shō
2. 文部科学省
3. MEXT
Ovarian Cancer Research Foundation 10.13039/100009845
Region: Oceania
gov (Trusts, charities, foundations (both public and private))
Labels4
1. Ovarian Cancer Research Foundation Inc.
2. OCRF Australia
3. The Ovarian Cancer Research Foundation
4. OCRF
Awards1
1. 14771310

BibTeX

@article{Kobayashi_2007, title={Effect of transferrin receptor-targeted liposomal doxorubicin in P-glycoprotein-mediated drug resistant tumor cells}, volume={329}, ISSN={0378-5173}, url={http://dx.doi.org/10.1016/j.ijpharm.2006.08.039}, DOI={10.1016/j.ijpharm.2006.08.039}, number={1–2}, journal={International Journal of Pharmaceutics}, publisher={Elsevier BV}, author={Kobayashi, Tomotaka and Ishida, Tatsuhiro and Okada, Yurie and Ise, Saori and Harashima, Hideyoshi and Kiwada, Hiroshi}, year={2007}, month=feb, pages={94–102} }

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    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "1454",
      "DOI": "10.1016/S0021-9258(19)57324-0",
      "article-title": "Purification of the 170 to 180-kilodalton membrane glycoprotein associated with multidrug resistance. 170 to 180-kilodalton membrane glycoprotein is an ATPase",
      "volume": "263",
      "author": "Hamada",
      "year": "1988",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "201",
      "DOI": "10.1016/0005-2736(93)90105-9",
      "article-title": "Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases",
      "volume": "1151",
      "author": "Haran",
      "year": "1993",
      "journal-title": "Biochim. Biophys. Acta"
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "138",
      "DOI": "10.1016/0009-3084(75)90037-7",
      "article-title": "Permeability and integrity properties of lecithin-sphingomyelin liposomes",
      "volume": "15",
      "author": "Hertz",
      "year": "1975",
      "journal-title": "Chem. Phys. Lipids"
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "520",
      "DOI": "10.1152/physrev.1987.67.2.520",
      "article-title": "The physiology of transferrin and transferrin receptors",
      "volume": "67",
      "author": "Huebers",
      "year": "1987",
      "journal-title": "Physiol. Rev."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "130",
      "DOI": "10.1002/ijc.10242",
      "article-title": "Intracellular targeting therapy of cisplatin-encapsulated transferrin-polyethylene glycol liposome on peritoneal dissemination of gastric cancer",
      "volume": "99",
      "author": "Iinuma",
      "year": "2002",
      "journal-title": "Int. J. Cancer"
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "1042",
      "DOI": "10.1023/A:1010960900254",
      "article-title": "Liposomes bearing polyethyleneglycol-coupled transferrin with intracellular targeting property to the solid tumors in vivo",
      "volume": "18",
      "author": "Ishida",
      "year": "2001",
      "journal-title": "Pharm. Res."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "144",
      "DOI": "10.1016/S0005-2736(01)00409-6",
      "article-title": "Targeted delivery and triggered release of liposomal doxorubicin enhances cytotoxicity against human B lymphoma cells",
      "volume": "1515",
      "author": "Ishida",
      "year": "2001",
      "journal-title": "Biochim. Biophys. Acta"
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "403",
      "DOI": "10.1016/j.jconrel.2003.12.011",
      "article-title": "Effect of the physicochemical properties of initially injected liposomes on the clearance of subsequently injected PEGylated liposomes in mice",
      "volume": "95",
      "author": "Ishida",
      "year": "2004",
      "journal-title": "J. Control. Release"
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "115",
      "DOI": "10.1016/0014-5793(96)00521-2",
      "article-title": "Liposomes with detachable polymer coating: destabilization and fusion of dioleoylphosphatidylethanolamine vesicles triggered by cleavage of surface-grafted poly(ethylene glycol)",
      "volume": "388",
      "author": "Kirpotin",
      "year": "1996",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib27",
      "first-page": "3320",
      "article-title": "In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma",
      "volume": "58",
      "author": "Lopes de Menezes",
      "year": "1998",
      "journal-title": "Cancer Res."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "271",
      "DOI": "10.1016/S1368-7646(03)00082-7",
      "article-title": "Liposome-based approaches to overcome anticancer drug resistance",
      "volume": "6",
      "author": "Mamot",
      "year": "2003",
      "journal-title": "Drug Resist. Updat."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib29",
      "first-page": "825",
      "article-title": "Daunorubicin uptake by leukemic cells: correlations with treatment outcome and MDR1 expression",
      "volume": "7",
      "author": "Marie",
      "year": "1993",
      "journal-title": "Leukemia"
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "978",
      "DOI": "10.1002/jps.2600791107",
      "article-title": "Characterization of in vivo immunoliposome targeting to pulmonary endothelium",
      "volume": "79",
      "author": "Maruyama",
      "year": "1990",
      "journal-title": "J. Pharm. Sci."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "77",
      "DOI": "10.1016/S0168-3659(01)00460-6",
      "article-title": "Possibility of the reversal of multidrug resistance and the avoidance of side effects by liposomes modified with MRK-16, a monoclonal antibody to P-glycoprotein",
      "volume": "77",
      "author": "Matsuo",
      "year": "2001",
      "journal-title": "J. Control. Release"
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "482",
      "DOI": "10.1038/bjc.1995.98",
      "article-title": "Pharmacology of liposomal vincristine in mice bearing L1210 ascitic and B16/BL6 solid tumours",
      "volume": "71",
      "author": "Mayer",
      "year": "1995",
      "journal-title": "Brit. J. Cancer"
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "55",
      "DOI": "10.1016/0022-1759(83)90303-4",
      "article-title": "Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays",
      "volume": "65",
      "author": "Mosmann",
      "year": "1983",
      "journal-title": "J. Immunol. Meth."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "935",
      "DOI": "10.1248/bpb.17.935",
      "article-title": "Effects of fluidity and vesicle size on antitumor activity and myelosuppressive activity of liposomes loaded with daunorubicin",
      "volume": "17",
      "author": "Nagayasu",
      "year": "1994",
      "journal-title": "Biol. Pharm. Bull."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "259",
      "DOI": "10.1007/BF00685532",
      "article-title": "Sensitization of multidrug-resistant colon cancer cells to doxorubicin encapsulated in liposomes",
      "volume": "28",
      "author": "Oudard",
      "year": "1991",
      "journal-title": "Cancer Chemother. Pharmacol."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "268",
      "DOI": "10.1002/(SICI)1097-0215(19990412)81:2<268::AID-IJC17>3.0.CO;2-1",
      "article-title": "GD2-mediated melanoma cell targeting and cytotoxicity of liposome-entrapped fenretinide",
      "volume": "81",
      "author": "Pagnan",
      "year": "1999",
      "journal-title": "Int. J. Cancer"
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib37",
      "first-page": "219",
      "article-title": "Therapeutic efficacy of a new topoisomerase I and II inhibitor TAS-103, against both P-glycoprotein-expressing and -nonexpressing drug-resistant human small-cell lung cancer",
      "volume": "11",
      "author": "Parajuli",
      "year": "1999",
      "journal-title": "Oncol. Res."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib38",
      "first-page": "1172",
      "article-title": "Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery",
      "volume": "8",
      "author": "Park",
      "year": "2002",
      "journal-title": "Clin. Cancer Res."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib39",
      "doi-asserted-by": "crossref",
      "first-page": "561",
      "DOI": "10.1124/pr.54.4.561",
      "article-title": "Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway",
      "volume": "54",
      "author": "Qian",
      "year": "2002",
      "journal-title": "Pharmacol. Rev."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib40",
      "doi-asserted-by": "crossref",
      "first-page": "1909",
      "DOI": "10.1093/jnci/84.24.1909",
      "article-title": "Liposome-mediated modulation of multidrug resistance in human HL-60 leukemia cells",
      "volume": "84",
      "author": "Rahman",
      "year": "1992",
      "journal-title": "J. Natl. Cancer Inst."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib41",
      "doi-asserted-by": "crossref",
      "first-page": "1151",
      "DOI": "10.1016/S0006-2952(97)00326-2",
      "article-title": "Flip-flop of doxorubicin across erythrocyte and lipid membranes",
      "volume": "54",
      "author": "Regev",
      "year": "1997",
      "journal-title": "Biochem. Pharmacol."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib42",
      "doi-asserted-by": "crossref",
      "first-page": "37577",
      "DOI": "10.1074/jbc.M101786200",
      "article-title": "Determination of the upper size limit for uptake and processing of ligands by the asialoglycoprotein receptor on hepatocytes in vitro and in vivo",
      "volume": "276",
      "author": "Rensen",
      "year": "2001",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib43",
      "doi-asserted-by": "crossref",
      "first-page": "817",
      "DOI": "10.1038/316817a0",
      "article-title": "Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines",
      "volume": "316",
      "author": "Riordan",
      "year": "1985",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib44",
      "doi-asserted-by": "crossref",
      "first-page": "299",
      "DOI": "10.1007/s00280-001-0405-3",
      "article-title": "Lack of activity of stealth liposomal doxorubicin in the treatment of patients with anthracycline-resistant breast cancer",
      "volume": "49",
      "author": "Rivera",
      "year": "2002",
      "journal-title": "Cancer Chemother. Pharmacol."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib45",
      "first-page": "7190",
      "article-title": "Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs",
      "volume": "62",
      "author": "Sapra",
      "year": "2002",
      "journal-title": "Cancer Res."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib46",
      "first-page": "1545",
      "article-title": "Membrane transport proteins associated with drug resistance expressed in human melanoma",
      "volume": "147",
      "author": "Schadendorf",
      "year": "1995",
      "journal-title": "Am. J. Pathol."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib47",
      "doi-asserted-by": "crossref",
      "first-page": "483",
      "DOI": "10.1007/s002800050849",
      "article-title": "Circumvention of multidrug resistance by a quinoline derivative, MS-209, in multidrug-resistant human small-cell lung cancer cells and its synergistic interaction with cyclosporin A or verapamil",
      "volume": "42",
      "author": "Shrivastava",
      "year": "1998",
      "journal-title": "Cancer Chemother. Pharmacol."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib48",
      "doi-asserted-by": "crossref",
      "first-page": "443",
      "DOI": "10.2174/138161280506230110111312",
      "article-title": "Transferrin as a targeting ligand for liposomes and anticancer drugs",
      "volume": "5",
      "author": "Singh",
      "year": "1999",
      "journal-title": "Curr. Pharm. Des."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib49",
      "first-page": "3221",
      "article-title": "Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines",
      "volume": "53",
      "author": "Slovak",
      "year": "1993",
      "journal-title": "Cancer Res."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib50",
      "doi-asserted-by": "crossref",
      "first-page": "349",
      "DOI": "10.1016/0006-2952(91)90531-9",
      "article-title": "P-glycoprotein drug efflux pump involved in the mechanisms of intrinsic drug resistance in various colon cancer cell lines. Evidence for a saturation of active daunorubicin transport",
      "volume": "41",
      "author": "Spoelstra",
      "year": "1991",
      "journal-title": "Biochem. Pharmacol."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib51",
      "doi-asserted-by": "crossref",
      "first-page": "1098",
      "DOI": "10.1016/0006-291X(92)91310-M",
      "article-title": "Effect of liposomes on P-glycoprotein function in multidrug resistant cells",
      "volume": "187",
      "author": "Thierry",
      "year": "1992",
      "journal-title": "Biochem. Biophys Res. Commun."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib52",
      "doi-asserted-by": "crossref",
      "first-page": "572",
      "DOI": "10.1096/fasebj.7.6.8097173",
      "article-title": "Modulation of doxorubicin resistance in multidrug-resistant cells by liposomes",
      "volume": "7",
      "author": "Thierry",
      "year": "1993",
      "journal-title": "FASEB J."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib53",
      "doi-asserted-by": "crossref",
      "first-page": "3004",
      "DOI": "10.1073/pnas.84.9.3004",
      "article-title": "Expression of a full-length cDNA for the human \u201cMDR1\u201d gene confers resistance to colchicine, doxorubicin, and vinblastine",
      "volume": "84",
      "author": "Ueda",
      "year": "1987",
      "journal-title": "Proc. Natl. Acad. Sci. U.S.A."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib54",
      "first-page": "3241",
      "article-title": "Increased accumulation of drugs in multidrug-resistant cells induced by liposomes",
      "volume": "52",
      "author": "Warren",
      "year": "1992",
      "journal-title": "Cancer Res."
    },
    {
      "key": "10.1016/j.ijpharm.2006.08.039_bib55",
      "doi-asserted-by": "crossref",
      "first-page": "2941",
      "DOI": "10.1089/10430349950016357",
      "article-title": "Transferrin-liposome-mediated systemic p53 gene therapy in combination with radiation results in regression of human head and neck cancer xenografts",
      "volume": "10",
      "author": "Xu",
      "year": "1999",
      "journal-title": "Hum. Gene. Ther."
    }
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