DOI: 10.1016/j.gde.2005.04.008. Cilia and disease

Cilia and disease

10.1016/j.gde.2005.04.008

Crossref journal-article

Elsevier BV

Current Opinion in Genetics & Development (78)

Bibliography

Eley, L., Yates, L. M., & Goodship, J. A. (2005). Cilia and disease. Current Opinion in Genetics & Development, 15(3), 308â314.

Authors 3

Lorraine Eley (first)
Laura M Yates (additional)
Judith A Goodship (additional)

References 48 Referenced 115

10.1083/jcb.91.3.125s / J Cell Biol / Cilia, flagella, and microtubules by Haimo (1981)
10.1083/jcb.53.2.494 / J Cell Biol / The ciliary necklace. A ciliary membrane specialization by Gilula (1972)
10.1002/jcb.20323 / J Cell Biochem / Intraflagellar transport and the flagellar tip complex by Sloboda (2004)
10.1038/nrm952 / Nat Rev Mol Cell Biol / Intraflagellar transport by Rosenbaum (2002)
10.1002/cm.10035 / Cell Motil Cytoskeleton / A healthy understanding of intraflagellar transport by Sloboda (2002)
10.1038/ng817 / Nat Genet / Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left–right asymmetry by Olbrich (2002)
10.1086/302683 / Am J Hum Genet / Loss-of-function mutations in a human gene related to Chlamydomonas reinhardtii dynein IC78 result in primary ciliary dyskinesia by Pennarun (1999)
10.1073/pnas.152337699 / Proc Natl Acad Sci USA / Mutations in the DNAH11 (axonemal heavy chain dynein type 11) gene cause one form of situs inversus totalis and most likely primary ciliary dyskinesia by Bartoloni (2002)
10.1093/hmg/ddh219 / Hum Mol Genet / Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation by Ibanez-Tallon (2004)
10.1111/j.1523-1755.2004.00844.x / Kidney Int / Polyductin, the PKHD1 gene product, comprises isoforms expressed in plasma membrane, primary cilium, and cytoplasm by Menezes (2004)
10.1038/ng1217 / Nat Genet / Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left–right axis determination by Otto (2003)
10.1097/01.ASN.0000113793.12558.1D / J Am Soc Nephrol / The autosomal recessive polycystic kidney disease protein is localized to primary cilia, with concentration in the basal body area by Wang (2004)
10.1097/01.ASN.0000029587.47950.25 / J Am Soc Nephrol / The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia by Yoder (2002)
10.1073/pnas.0400073101 / Proc Natl Acad Sci USA / PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells by Zhang (2004)
10.1093/hmg/ddg274 / Hum Mol Genet / Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia by Ward (2003)
10.1242/dev.01240 / Development / A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney by Sun (2004)
10.1016/j.cub.2004.10.011 / Curr Biol / Human cilia proteome contains homolog of zebrafish polycystic kidney disease gene qilin by Marshall (2004)
10.1007/s00232-001-0075-4 / J Membr Biol / Bending the MDCK cell primary cilium increases intracellular calcium by Praetorius (2001)
10.1007/s00232-002-1042-4 / J Membr Biol / Removal of the MDCK cell primary cilium abolishes flow sensing by Praetorius (2003)
10.1038/ng1076 / Nat Genet / Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells by Nauli (2003)
10.1172/JCI21753 / J Clin Invest / Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus by Chauvet (2004)
10.1007/978-1-4615-0067-4_20 / Adv Exp Med Biol / Photoreceptor intersegmental transport and retinal degeneration: a conserved pathway common to motile and sensory cilia by Besharse (2003)
10.1016/S0092-8674(00)00023-4 / Cell / Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors by Marszalek (2000)
{'key': '10.1016/j.gde.2005.04.008_bib24', 'first-page': '22', 'article-title': 'Identification and subcellular localization of the RP1 protein in human and mouse photoreceptors', 'volume': '43', 'author': 'Liu', 'year': '2002', 'journal-title': 'Invest Ophthalmol Vis Sci'} / Invest Ophthalmol Vis Sci / Identification and subcellular localization of the RP1 protein in human and mouse photoreceptors by Liu (2002)
10.1167/iovs.02-1206 / Invest Ophthalmol Vis Sci / RPGR isoforms in photoreceptor connecting cilia and the transitional zone of motile cilia by Hong (2003)
10.1002/(SICI)1097-0169(1997)37:3<240::AID-CM6>3.0.CO;2-A / Cell Motil Cytoskeleton / Myosin VIIa, the product of the Usher 1B syndrome gene, is concentrated in the connecting cilia of photoreceptor cells by Liu (1997)
10.1523/JNEUROSCI.19-15-06267.1999 / J Neurosci / Myosin VIIa participates in opsin transport through the photoreceptor cilium by Liu (1999)
10.1038/nature02030 / Nature / Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome by Ansley (2003)
10.1002/neu.10124 / J Neurobiol / Planar cell polarity in the inner ear: how do hair cells acquire their oriented structure? by Lewis (2002)
10.1016/S0378-5955(02)00334-9 / Hear Res / Stereocilia defects in waltzer (Cdh23), shaker1 (Myo7a) and double waltzer/shaker1 mutant mice by Holme (2002)
10.1038/ng1208 / Nat Genet / Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31 by Mburu (2003)
10.1007/BF01179815 / J Neurocytol / The kinocilium of auditory hair cells and evidence for its morphogenetic role during the regeneration of stereocilia and cuticular plates by Sobkowicz (1995)
10.1016/S0959-4388(99)80063-4 / Curr Opin Neurobiol / Calcium signalling and regulation in olfactory neurons by Menini (1999)
10.1038/ng1418 / Nat Genet / Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse by Kulaga (2004)
10.1016/S0092-8674(00)81705-5 / Cell / Randomization of left–right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein by Nonaka (1998)
10.1038/nature00849 / Nature / Determination of left-right patterning of the mouse embryo by artificial nodal flow by Nonaka (2002)
10.1016/S0092-8674(03)00511-7 / Cell / Two populations of node monocilia initiate left–right asymmetry in the mouse by McGrath (2003)
10.1073/pnas.0402001101 / Proc Natl Acad Sci USA / Fluid-dynamical basis of the embryonic development of left–right asymmetry in vertebrates by Cartwright (2004)
10.1016/S1097-2765(00)80197-5 / Mol Cell / Abnormal nodal flow precedes situs inversus in iv and inv mice by Okada (1999)
10.1242/dev.126.23.5495 / Development / Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left–right asymmetries by Supp (1999)
10.1242/dev.127.11.2347 / Development / The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left–right axis determination by Murcia (2000)
10.1073/pnas.96.9.5043 / Proc Natl Acad Sci USA / Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II by Marszalek (1999)
10.1083/jcb.145.4.825 / J Cell Biol / Left–right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A−/− mice analysis by Takeda (1999)
10.1128/MCB.24.10.4417-4427.2004 / Mol Cell Biol / The transcription factor RFX3 directs nodal cilium development and left–right asymmetry specification by Bonnafe (2004)
10.1242/dev.01389 / Development / Targeted deletion of the novel cytoplasmic dynein mD2LIC disrupts the embryonic organiser, formation of the body axes and specification of ventral cell fates by Rana (2004)
10.1038/nature02061 / Nature / Hedgehog signalling in the mouse requires intraflagellar transport proteins by Huangfu (2003)
10.1038/ng1520 / Nat Genet / Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Løken syndrome and interacts with RPGR and calmodulin by Otto (2005)
10.1164/rccm.200411-1583OC / Am J Respir Crit Care Med / Mis-localization of DNAH5 and DNAH9 in respiratory cells from primary ciliary dyskinesia patients by Fliegauf (2005)

Dates

Type	When
Created	20 years, 4 months ago (April 24, 2005, 7:16 a.m.)
Deposited	4 years, 1 month ago (July 9, 2021, 1:03 p.m.)
Indexed	2 days, 19 hours ago (Sept. 3, 2025, 6:17 a.m.)
Issued	20 years, 3 months ago (June 1, 2005)
Published	20 years, 3 months ago (June 1, 2005)
Published Print	20 years, 3 months ago (June 1, 2005)

Funders 0

None

BibTeX

@article{Eley_2005, title={Cilia and disease}, volume={15}, ISSN={0959-437X}, url={http://dx.doi.org/10.1016/j.gde.2005.04.008}, DOI={10.1016/j.gde.2005.04.008}, number={3}, journal={Current Opinion in Genetics & Development}, publisher={Elsevier BV}, author={Eley, Lorraine and Yates, Laura M and Goodship, Judith A}, year={2005}, month=jun, pages={308–314} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        9,
        3
      ]
    ],
    "date-time": "2025-09-03T10:17:17Z",
    "timestamp": 1756894637550
  },
  "reference-count": 48,
  "publisher": "Elsevier BV",
  "issue": "3",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2005,
            6,
            1
          ]
        ],
        "date-time": "2005-06-01T00:00:00Z",
        "timestamp": 1117584000000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2005,
        6
      ]
    ]
  },
  "DOI": "10.1016/j.gde.2005.04.008",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2005,
        4,
        24
      ]
    ],
    "date-time": "2005-04-24T11:16:06Z",
    "timestamp": 1114341366000
  },
  "page": "308-314",
  "source": "Crossref",
  "is-referenced-by-count": 115,
  "title": "Cilia and disease",
  "prefix": "10.1016",
  "volume": "15",
  "author": [
    {
      "given": "Lorraine",
      "family": "Eley",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Laura M",
      "family": "Yates",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Judith A",
      "family": "Goodship",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/j.gde.2005.04.008_bib1",
      "doi-asserted-by": "crossref",
      "first-page": "125s",
      "DOI": "10.1083/jcb.91.3.125s",
      "article-title": "Cilia, flagella, and microtubules",
      "volume": "91",
      "author": "Haimo",
      "year": "1981",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib2",
      "doi-asserted-by": "crossref",
      "first-page": "494",
      "DOI": "10.1083/jcb.53.2.494",
      "article-title": "The ciliary necklace. A ciliary membrane specialization",
      "volume": "53",
      "author": "Gilula",
      "year": "1972",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib3",
      "doi-asserted-by": "crossref",
      "first-page": "266",
      "DOI": "10.1002/jcb.20323",
      "article-title": "Intraflagellar transport and the flagellar tip complex",
      "volume": "94",
      "author": "Sloboda",
      "year": "2004",
      "journal-title": "J Cell Biochem"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib4",
      "doi-asserted-by": "crossref",
      "first-page": "813",
      "DOI": "10.1038/nrm952",
      "article-title": "Intraflagellar transport",
      "volume": "3",
      "author": "Rosenbaum",
      "year": "2002",
      "journal-title": "Nat Rev Mol Cell Biol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib5",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1002/cm.10035",
      "article-title": "A healthy understanding of intraflagellar transport",
      "volume": "52",
      "author": "Sloboda",
      "year": "2002",
      "journal-title": "Cell Motil Cytoskeleton"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib6",
      "doi-asserted-by": "crossref",
      "first-page": "143",
      "DOI": "10.1038/ng817",
      "article-title": "Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left\u2013right asymmetry",
      "volume": "30",
      "author": "Olbrich",
      "year": "2002",
      "journal-title": "Nat Genet"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "1508",
      "DOI": "10.1086/302683",
      "article-title": "Loss-of-function mutations in a human gene related to Chlamydomonas reinhardtii dynein IC78 result in primary ciliary dyskinesia",
      "volume": "65",
      "author": "Pennarun",
      "year": "1999",
      "journal-title": "Am J Hum Genet"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib8",
      "doi-asserted-by": "crossref",
      "first-page": "10282",
      "DOI": "10.1073/pnas.152337699",
      "article-title": "Mutations in the DNAH11 (axonemal heavy chain dynein type 11) gene cause one form of situs inversus totalis and most likely primary ciliary dyskinesia",
      "volume": "99",
      "author": "Bartoloni",
      "year": "2002",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "2133",
      "DOI": "10.1093/hmg/ddh219",
      "article-title": "Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation",
      "volume": "13",
      "author": "Ibanez-Tallon",
      "year": "2004",
      "journal-title": "Hum Mol Genet"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "1345",
      "DOI": "10.1111/j.1523-1755.2004.00844.x",
      "article-title": "Polyductin, the PKHD1 gene product, comprises isoforms expressed in plasma membrane, primary cilium, and cytoplasm",
      "volume": "66",
      "author": "Menezes",
      "year": "2004",
      "journal-title": "Kidney Int"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib11",
      "doi-asserted-by": "crossref",
      "first-page": "413",
      "DOI": "10.1038/ng1217",
      "article-title": "Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left\u2013right axis determination",
      "volume": "34",
      "author": "Otto",
      "year": "2003",
      "journal-title": "Nat Genet"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "592",
      "DOI": "10.1097/01.ASN.0000113793.12558.1D",
      "article-title": "The autosomal recessive polycystic kidney disease protein is localized to primary cilia, with concentration in the basal body area",
      "volume": "15",
      "author": "Wang",
      "year": "2004",
      "journal-title": "J Am Soc Nephrol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "2508",
      "DOI": "10.1097/01.ASN.0000029587.47950.25",
      "article-title": "The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia",
      "volume": "13",
      "author": "Yoder",
      "year": "2002",
      "journal-title": "J Am Soc Nephrol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib14",
      "doi-asserted-by": "crossref",
      "first-page": "2311",
      "DOI": "10.1073/pnas.0400073101",
      "article-title": "PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells",
      "volume": "101",
      "author": "Zhang",
      "year": "2004",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "2703",
      "DOI": "10.1093/hmg/ddg274",
      "article-title": "Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia",
      "volume": "12",
      "author": "Ward",
      "year": "2003",
      "journal-title": "Hum Mol Genet"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib16_1",
      "doi-asserted-by": "crossref",
      "first-page": "4085",
      "DOI": "10.1242/dev.01240",
      "article-title": "A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney",
      "volume": "131",
      "author": "Sun",
      "year": "2004",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib17",
      "doi-asserted-by": "crossref",
      "first-page": "R913",
      "DOI": "10.1016/j.cub.2004.10.011",
      "article-title": "Human cilia proteome contains homolog of zebrafish polycystic kidney disease gene qilin",
      "volume": "14",
      "author": "Marshall",
      "year": "2004",
      "journal-title": "Curr Biol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "71",
      "DOI": "10.1007/s00232-001-0075-4",
      "article-title": "Bending the MDCK cell primary cilium increases intracellular calcium",
      "volume": "184",
      "author": "Praetorius",
      "year": "2001",
      "journal-title": "J Membr Biol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "69",
      "DOI": "10.1007/s00232-002-1042-4",
      "article-title": "Removal of the MDCK cell primary cilium abolishes flow sensing",
      "volume": "191",
      "author": "Praetorius",
      "year": "2003",
      "journal-title": "J Membr Biol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "129",
      "DOI": "10.1038/ng1076",
      "article-title": "Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells",
      "volume": "33",
      "author": "Nauli",
      "year": "2003",
      "journal-title": "Nat Genet"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "1433",
      "DOI": "10.1172/JCI21753",
      "article-title": "Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus",
      "volume": "114",
      "author": "Chauvet",
      "year": "2004",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "157",
      "DOI": "10.1007/978-1-4615-0067-4_20",
      "article-title": "Photoreceptor intersegmental transport and retinal degeneration: a conserved pathway common to motile and sensory cilia",
      "volume": "533",
      "author": "Besharse",
      "year": "2003",
      "journal-title": "Adv Exp Med Biol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "175",
      "DOI": "10.1016/S0092-8674(00)00023-4",
      "article-title": "Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors",
      "volume": "102",
      "author": "Marszalek",
      "year": "2000",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib24",
      "first-page": "22",
      "article-title": "Identification and subcellular localization of the RP1 protein in human and mouse photoreceptors",
      "volume": "43",
      "author": "Liu",
      "year": "2002",
      "journal-title": "Invest Ophthalmol Vis Sci"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "2413",
      "DOI": "10.1167/iovs.02-1206",
      "article-title": "RPGR isoforms in photoreceptor connecting cilia and the transitional zone of motile cilia",
      "volume": "44",
      "author": "Hong",
      "year": "2003",
      "journal-title": "Invest Ophthalmol Vis Sci"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "240",
      "DOI": "10.1002/(SICI)1097-0169(1997)37:3<240::AID-CM6>3.0.CO;2-A",
      "article-title": "Myosin VIIa, the product of the Usher 1B syndrome gene, is concentrated in the connecting cilia of photoreceptor cells",
      "volume": "37",
      "author": "Liu",
      "year": "1997",
      "journal-title": "Cell Motil Cytoskeleton"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "6267",
      "DOI": "10.1523/JNEUROSCI.19-15-06267.1999",
      "article-title": "Myosin VIIa participates in opsin transport through the photoreceptor cilium",
      "volume": "19",
      "author": "Liu",
      "year": "1999",
      "journal-title": "J Neurosci"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib28_1",
      "doi-asserted-by": "crossref",
      "first-page": "628",
      "DOI": "10.1038/nature02030",
      "article-title": "Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome",
      "volume": "425",
      "author": "Ansley",
      "year": "2003",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "190",
      "DOI": "10.1002/neu.10124",
      "article-title": "Planar cell polarity in the inner ear: how do hair cells acquire their oriented structure?",
      "volume": "53",
      "author": "Lewis",
      "year": "2002",
      "journal-title": "J Neurobiol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "13",
      "DOI": "10.1016/S0378-5955(02)00334-9",
      "article-title": "Stereocilia defects in waltzer (Cdh23), shaker1 (Myo7a) and double waltzer/shaker1 mutant mice",
      "volume": "169",
      "author": "Holme",
      "year": "2002",
      "journal-title": "Hear Res"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "421",
      "DOI": "10.1038/ng1208",
      "article-title": "Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31",
      "volume": "34",
      "author": "Mburu",
      "year": "2003",
      "journal-title": "Nat Genet"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "633",
      "DOI": "10.1007/BF01179815",
      "article-title": "The kinocilium of auditory hair cells and evidence for its morphogenetic role during the regeneration of stereocilia and cuticular plates",
      "volume": "24",
      "author": "Sobkowicz",
      "year": "1995",
      "journal-title": "J Neurocytol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "419",
      "DOI": "10.1016/S0959-4388(99)80063-4",
      "article-title": "Calcium signalling and regulation in olfactory neurons",
      "volume": "9",
      "author": "Menini",
      "year": "1999",
      "journal-title": "Curr Opin Neurobiol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib34_1",
      "doi-asserted-by": "crossref",
      "first-page": "994",
      "DOI": "10.1038/ng1418",
      "article-title": "Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse",
      "volume": "36",
      "author": "Kulaga",
      "year": "2004",
      "journal-title": "Nat Genet"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "829",
      "DOI": "10.1016/S0092-8674(00)81705-5",
      "article-title": "Randomization of left\u2013right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein",
      "volume": "95",
      "author": "Nonaka",
      "year": "1998",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "96",
      "DOI": "10.1038/nature00849",
      "article-title": "Determination of left-right patterning of the mouse embryo by artificial nodal flow",
      "volume": "418",
      "author": "Nonaka",
      "year": "2002",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib37_1",
      "doi-asserted-by": "crossref",
      "first-page": "61",
      "DOI": "10.1016/S0092-8674(03)00511-7",
      "article-title": "Two populations of node monocilia initiate left\u2013right asymmetry in the mouse",
      "volume": "114",
      "author": "McGrath",
      "year": "2003",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib38",
      "doi-asserted-by": "crossref",
      "first-page": "7234",
      "DOI": "10.1073/pnas.0402001101",
      "article-title": "Fluid-dynamical basis of the embryonic development of left\u2013right asymmetry in vertebrates",
      "volume": "101",
      "author": "Cartwright",
      "year": "2004",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib39",
      "doi-asserted-by": "crossref",
      "first-page": "459",
      "DOI": "10.1016/S1097-2765(00)80197-5",
      "article-title": "Abnormal nodal flow precedes situs inversus in iv and inv mice",
      "volume": "4",
      "author": "Okada",
      "year": "1999",
      "journal-title": "Mol Cell"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib40",
      "doi-asserted-by": "crossref",
      "first-page": "5495",
      "DOI": "10.1242/dev.126.23.5495",
      "article-title": "Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left\u2013right asymmetries",
      "volume": "126",
      "author": "Supp",
      "year": "1999",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib41",
      "doi-asserted-by": "crossref",
      "first-page": "2347",
      "DOI": "10.1242/dev.127.11.2347",
      "article-title": "The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left\u2013right axis determination",
      "volume": "127",
      "author": "Murcia",
      "year": "2000",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib42",
      "doi-asserted-by": "crossref",
      "first-page": "5043",
      "DOI": "10.1073/pnas.96.9.5043",
      "article-title": "Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II",
      "volume": "96",
      "author": "Marszalek",
      "year": "1999",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib43",
      "doi-asserted-by": "crossref",
      "first-page": "825",
      "DOI": "10.1083/jcb.145.4.825",
      "article-title": "Left\u2013right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A\u2212/\u2212 mice analysis",
      "volume": "145",
      "author": "Takeda",
      "year": "1999",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib44",
      "doi-asserted-by": "crossref",
      "first-page": "4417",
      "DOI": "10.1128/MCB.24.10.4417-4427.2004",
      "article-title": "The transcription factor RFX3 directs nodal cilium development and left\u2013right asymmetry specification",
      "volume": "24",
      "author": "Bonnafe",
      "year": "2004",
      "journal-title": "Mol Cell Biol"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib45",
      "doi-asserted-by": "crossref",
      "first-page": "4999",
      "DOI": "10.1242/dev.01389",
      "article-title": "Targeted deletion of the novel cytoplasmic dynein mD2LIC disrupts the embryonic organiser, formation of the body axes and specification of ventral cell fates",
      "volume": "131",
      "author": "Rana",
      "year": "2004",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib46",
      "doi-asserted-by": "crossref",
      "first-page": "83",
      "DOI": "10.1038/nature02061",
      "article-title": "Hedgehog signalling in the mouse requires intraflagellar transport proteins",
      "volume": "426",
      "author": "Huangfu",
      "year": "2003",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib47",
      "doi-asserted-by": "crossref",
      "first-page": "282",
      "DOI": "10.1038/ng1520",
      "article-title": "Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-L\u00f8ken syndrome and interacts with RPGR and calmodulin",
      "volume": "37",
      "author": "Otto",
      "year": "2005",
      "journal-title": "Nat Genet"
    },
    {
      "key": "10.1016/j.gde.2005.04.008_bib48",
      "doi-asserted-by": "crossref",
      "DOI": "10.1164/rccm.200411-1583OC",
      "article-title": "Mis-localization of DNAH5 and DNAH9 in respiratory cells from primary ciliary dyskinesia patients",
      "author": "Fliegauf",
      "year": "2005",
      "journal-title": "Am J Respir Crit Care Med"
    }
  ],
  "container-title": "Current Opinion in Genetics &amp; Development",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0959437X05000602?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0959437X05000602?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2021,
        7,
        9
      ]
    ],
    "date-time": "2021-07-09T17:03:03Z",
    "timestamp": 1625850183000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0959437X05000602"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2005,
        6
      ]
    ]
  },
  "references-count": 48,
  "journal-issue": {
    "issue": "3",
    "published-print": {
      "date-parts": [
        [
          2005,
          6
        ]
      ]
    }
  },
  "alternative-id": [
    "S0959437X05000602"
  ],
  "URL": "http://dx.doi.org/10.1016/j.gde.2005.04.008",
  "relation": {},
  "ISSN": [
    "0959-437X"
  ],
  "subject": [],
  "container-title-short": "Current Opinion in Genetics &amp; Development",
  "published": {
    "date-parts": [
      [
        2005,
        6
      ]
    ]
  }
}