Abstract
Rat kidneys were sectioned by cryoultramicrotomy and dried at room temperature. The samples were covered with a thin silver layer and analyzed in an imaging TOF‐SIMS instrument equipped with a Ga+‐source. The cholesterol signal showed a high concentration in the nuclear areas of the epithelial cells and a lower concentration over areas representing the basal lamina of renal tubules. A more diffuse distribution of cholesterol was also found over areas representing the cytoplasm or plasma membrane of the epithelial cells.
References
18
Referenced
96
10.1016/0039-6028(94)90658-0
10.1016/0168-1176(94)04119-R
10.1021/ac971763g
10.1016/S1044-0305(99)00145-2
10.1093/jmicro/52.3.349
10.1093/jmicro/50.4.325
10.1016/S0169-4332(02)00708-0
10.1021/ac020125h
10.1021/ac0302105
10.1016/S0927-7765(03)00066-3
10.1021/ac035243z
10.1111/j.1365-2818.1986.tb02772.x
10.1046/j.1365-2818.2003.01244.x
10.1021/ac0207675
10.1016/0304-4157(83)90007-2
10.1177/002215549704500903
10.1007/BF00490254
10.1177/002215540205000105
Dates
Type | When |
---|---|
Created | 21 years, 3 months ago (May 11, 2004, 6:36 a.m.) |
Deposited | 1 year, 11 months ago (Sept. 16, 2023, 2:20 a.m.) |
Indexed | 1 year ago (Aug. 10, 2024, 11:14 a.m.) |
Issued | 21 years, 3 months ago (May 10, 2004) |
Published | 21 years, 3 months ago (May 10, 2004) |
Published Online | 21 years, 3 months ago (May 10, 2004) |
Published Print | 21 years, 3 months ago (May 21, 2004) |
@article{Nygren_2004, title={Bioimaging TOF‐SIMS: localization of cholesterol in rat kidney sections}, volume={566}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/j.febslet.2004.04.052}, DOI={10.1016/j.febslet.2004.04.052}, number={1–3}, journal={FEBS Letters}, publisher={Wiley}, author={Nygren, Håkan and Malmberg, Per and Kriegeskotte, Christian and Arlinghaus, Heinrich F.}, year={2004}, month=may, pages={291–293} }