DOI: 10.1016/j.ejmech.2011.09.006. Synthesis and characterization of novel bis(carboxylato)dichloridobis(ethylamine)platinum(IV) complexes with higher cytotoxicity than cisplatin

Synthesis and characterization of novel bis(carboxylato)dichloridobis(ethylamine)platinum(IV) complexes with higher cytotoxicity than cisplatin

10.1016/j.ejmech.2011.09.006

Crossref journal-article

Elsevier BV

European Journal of Medicinal Chemistry (78)

Bibliography

Varbanov, H., Valiahdi, S. M., Legin, A. A., Jakupec, M. A., Roller, A., Galanski, M. S., & Keppler, B. K. (2011). Synthesis and characterization of novel bis(carboxylato)dichloridobis(ethylamine)platinum(IV) complexes with higher cytotoxicity than cisplatin. European Journal of Medicinal Chemistry, 46(11), 5456â5464.

Authors 7

Hristo Varbanov (first)
Seied M. Valiahdi (additional)
Anton A. Legin (additional)
Michael A. Jakupec (additional)
Alexander Roller (additional)
Mathea S. Galanski (additional)
Bernhard K. Keppler (additional)

References 29 Referenced 72

10.1038/205698a0 / Nature / Inhibition of cell division in Escherichia coli by electrolysis products from a platinum electrode by Rosenberg (1965)
10.1039/c0dt00292e / Dalton Trans. / The status of platinum anticancer drugs in the clinic and in clinical trials by Wheate (2010)
10.1021/jm070280u / J. Med. Chem. / Basis for design and development of platinum(IV) anticancer complexes by Hall (2007)
10.2174/157489206777442287 / Recent Pat. Anticancer Drug Discov. / Recent developments in the field of anticancer platinum complexes by Galanski (2006)
10.2174/0929867054637626 / Curr. Med. Chem. / Update of the preclinical situation of anticancer platinum complexes: novel design strategies and innovative analytical approaches by Galanski (2005)
{'issue': '3', 'key': '10.1016/j.ejmech.2011.09.006_bib6', 'first-page': '709', 'article-title': 'Phase I and pharmacokinetic study of ormaplatin (tetraplatin, NSC 363812) administered on a day 1 and day 8 schedule', 'volume': '54', 'author': 'Schilder', 'year': '1994', 'journal-title': 'Cancer Res.'} / Cancer Res. / Phase I and pharmacokinetic study of ormaplatin (tetraplatin, NSC 363812) administered on a day 1 and day 8 schedule by Schilder (1994)
{'year': '2007', 'series-title': 'G.B. Inc, Orplanta. Satraplatin Capsules, in Advisory Committee Briefing Document', 'key': '10.1016/j.ejmech.2011.09.006_bib7'} / G.B. Inc, Orplanta. Satraplatin Capsules, in Advisory Committee Briefing Document (2007)
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http://www.clinicaltrials.gov, U.S National Library of Medicine, Bethesda, 1993.
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10.1016/S0020-1693(99)00613-1 / Inorg. Chim. Acta / Is reduction required for antitumor activity of platinum(IV) compounds? Characterisation of a platinum(IV)-nucleotide adduct [enPt(OCOCH3)3(5′-GMP)] by NMR spectroscopy and ESI-MS by Galanski (2000)
10.1071/CH9950793 / Aust. J. Chem. / The influence of the axial ligands of a series of platinum(IV) anti-cancer complexes on their reduction to platinum(II) and reaction with DNA by Ellis (1995)
10.1021/ic971047x / Inorg. Chem. / Reduction and anticancer activity of platinum(IV) complexes by Choi (1998)
{'key': '10.1016/j.ejmech.2011.09.006_bib14', 'first-page': '4539', 'article-title': 'In vitro biotransformations of tetrachloro(d, l-trans)-1,2-diaminocyclohexaneplatinum(IV) (tetraplatin) in rat plasma', 'volume': '50', 'author': 'Chaney', 'year': '1990', 'journal-title': 'Cancer Res.'} / Cancer Res. / In vitro biotransformations of tetrachloro(d, l-trans)-1,2-diaminocyclohexaneplatinum(IV) (tetraplatin) in rat plasma by Chaney (1990)
{'key': '10.1016/j.ejmech.2011.09.006_bib15', 'first-page': '3533', 'article-title': 'Identification of cis-dichloro-bis-isopropylamine platinum(II) as a major metabolite of iproplatin in humans', 'volume': '48', 'author': 'Pendyala', 'year': '1988', 'journal-title': 'Cancer Res.'} / Cancer Res. / Identification of cis-dichloro-bis-isopropylamine platinum(II) as a major metabolite of iproplatin in humans by Pendyala (1988)
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10.1021/jm070897b / J. Med. Chem. / Novel di- and tetracarboxylatoplatinum(IV) complexes. Synthesis, characterization, cytotoxic activity, and DNA platination by Reithofer (2007)
10.1016/j.jinorgbio.2008.07.006 / J. Inorg. Biochem. / Novel bis(carboxylato)dichlorido(ethane-1,2-diamine)platinum(IV) complexes with exceptionally high cytotoxicity by Reithofer (2008)
10.1002/cbdv.200890197 / Chem. Biodiv / Novel endothall containing platinum(IV) complexes – synthesis, characterization, and cytotoxic activity by Reithofer (2008)
10.1002/elps.200900522 / Electrophoresis / The first example of MEEKC-ICP-MS coupling and its application for the analysis of anticancer platinum complexes by Bytzek (2010)
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Dates

Type	When
Created	13 years, 11 months ago (Sept. 10, 2011, 5:37 a.m.)
Deposited	1 year, 6 months ago (Jan. 25, 2024, 5:30 a.m.)
Indexed	2 months, 4 weeks ago (May 26, 2025, 4:05 a.m.)
Issued	13 years, 9 months ago (Nov. 1, 2011)
Published	13 years, 9 months ago (Nov. 1, 2011)
Published Print	13 years, 9 months ago (Nov. 1, 2011)

Funders 4

Universität Wien 10.13039/501100003065
Region: Europe
pri (Universities (academic only))
Labels1
1. University of Vienna
Österreichische Forschungsförderungsgesellschaft 10.13039/501100004955
Region: Europe
gov (National government)
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1. Austrian Research Promotion Agency
2. Die Österreichische Forschungsförderungsgesellschaft
3. Österreichische Forschungsförderungsgesellschaft mbH
4. FFG – Austria
5. FFG
Austrian Science Fund 10.13039/501100002428
Region: Europe
gov (National government)
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1. Fonds zur Förderung der Wissenschaftlichen Forschung
2. FWF Der Wissenschaftsfonds
3. FWF Austrian Science Fund
4. Der Wissenschaftsfonds FWF
5. Österreichischer Wissenschaftsfonds
6. FWF
7. FFWF
8. FWF EN
Awards1
1. COST D39
Rat für Forschung und Technologieentwicklung 10.13039/501100010266
Region: Europe
gov (National government)
Labels3
1. Austrian Council
2. Austrian Council for Research and Technology Development
3. RFT

BibTeX

@article{Varbanov_2011, title={Synthesis and characterization of novel bis(carboxylato)dichloridobis(ethylamine)platinum(IV) complexes with higher cytotoxicity than cisplatin}, volume={46}, ISSN={0223-5234}, url={http://dx.doi.org/10.1016/j.ejmech.2011.09.006}, DOI={10.1016/j.ejmech.2011.09.006}, number={11}, journal={European Journal of Medicinal Chemistry}, publisher={Elsevier BV}, author={Varbanov, Hristo and Valiahdi, Seied M. and Legin, Anton A. and Jakupec, Michael A. and Roller, Alexander and Galanski, Mathea S. and Keppler, Bernhard K.}, year={2011}, month=nov, pages={5456–5464} }

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