DOI: 10.1016/j.cub.2005.05.050. The Drosophila Fragile X Mental Retardation Protein Controls Actin Dynamics by Directly Regulating Profilin in the Brain

The Drosophila Fragile X Mental Retardation Protein Controls Actin Dynamics by Directly Regulating Profilin in the Brain

10.1016/j.cub.2005.05.050

Crossref journal-article

Elsevier BV

Current Biology (78)

Bibliography

Reeve, S. P., Bassetto, L., Genova, G. K., Kleyner, Y., Leyssen, M., Jackson, F. R., & Hassan, B. A. (2005). The Drosophila Fragile X Mental Retardation Protein Controls Actin Dynamics by Directly Regulating Profilin in the Brain. Current Biology, 15(12), 1156â1163.

Authors 7

Simon P. Reeve (first)
Laura Bassetto (additional)
Ginka K. Genova (additional)
Yelena Kleyner (additional)
Maarten Leyssen (additional)
F. Rob Jackson (additional)
Bassem A. Hassan (additional)

References 25 Referenced 123

10.1097/00008480-200312000-00003 / Curr. Opin. Pediatr. / Understanding the biological underpinnings of fragile X syndrome by Chiurazzi (2003)
10.1159/000072845 / Cytogenet. Genome Res. / Understanding fragile X syndrome: Insights from animal models by Bakker (2003)
10.1128/MCB.20.22.8536-8547.2000 / Mol. Cell. Biol. / Characterisation of dFMR1, a Drosophila melanogaster homologue of the fragile X mental retardation protein by Wan (2000)
10.1016/S0092-8674(01)00566-9 / Cell / Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function by Darnell (2001)
10.1016/S0092-8674(01)00589-X / Cell / Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function by Zhang (2001)
10.1016/S0896-6273(02)00724-9 / Neuron / Drosophila lacking dfmr1 activity show defects in circadian output and fail to maintain courtship interest by Dockendorff (2002)
10.1242/dev.00792 / Development / Control of dendritic development by the Drosophila fragile X-related gene involves the small GTPase Rac1 by Lee (2003)
10.1016/S0960-9822(02)01036-9 / Curr. Biol. / A role for the Drosophila fragile X-related gene in circadian output by Inoue (2002)
10.1002/neu.480220503 / J. Neurobiol. / Characterisation and spatial distribution of the ELAV protein during Drosophila melanogaster development by Robinow (1991)
10.1016/S0896-6273(02)00731-6 / Neuron / Drosophila fragile X protein, DFXR, regulates neuronal morphology and function in the brain by Morales (2002)
10.1073/pnas.92.2.612 / Proc. Natl. Acad. Sci. USA / The period clock gene is expressed in central nervous system neurons which also produce a neuropeptide that reveals the projections of circadian pacemaker cells within the brain of Drosophila melanogaster by Helfrich-Förster (1995)
10.1093/hmg/9.8.1145 / Hum. Mol. Genet. / (Over)correction of FMR1 deficiency with YAC transgenics: Behavioural and physical features by Peier (2000)
10.1073/pnas.0304544101 / Proc. Natl. Acad. Sci. USA / Frontostriatal deficits in fragile X syndrome: Relation to FMR1 gene expression by Menon (2004)
10.1016/S0896-6273(00)81090-9 / Neuron / Profilin and the Abl tyrosine kinase are required for motor axon outgrowth in the Drosophila embryo by Wills (1999)
10.1016/S0092-8674(00)00068-4 / Cell / Ciboulot regulates actin assembly during Drosophila brain metamorphosis by Boquet (2000)
10.1242/dev.120.4.717 / Development / Profilin mutations disrupt multiple actin-dependent processes during Drosophila development by Verheyen (1994)
10.1016/S0896-6273(03)00354-4 / Neuron / CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein by Schenck (2003)
10.1038/416442a / Nature / Rac GTPases control axon growth, guidance and branching by Ng (2002)
10.1038/416438a / Nature / Rac function and regulation during Drosophila development by Hakeda-Suzuki (2002)
10.1073/pnas.97.7.3608 / Proc. Natl. Acad. Sci. USA / Differential regulation of circadian pacemaker output by separate clock genes in Drosophila by Park (2000)
10.1016/S0092-8674(00)81676-1 / Cell / A pdf neuropeptide gene mutation and ablation of Pdf neurons each cause severe abnormalities of behavioural circadian rhythms in Drosophila by Renn (1999)
10.1523/JNEUROSCI.1102-04.2004 / J. Neurosci. / Defective neuronal development in the mushroom bodies of Drosophila Fragile X mental retardation 1 mutants by Michel (2004)
10.1016/j.cub.2004.09.085 / Curr. Biol. / The Drosophila Fragile X gene negatively regulates neuronal elaboration and synaptic differentiation by Pan (2004)
10.1016/S0092-8674(01)00568-2 / Cell / Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in Fragile X syndrome by Brown (2001)
10.1152/physrev.00026.2002 / Physiol. Rev. / Actin binding proteins: Regulation of cytoskeletal microfilaments by dos Remedios (2003)

Dates

Type	When
Created	20 years, 2 months ago (June 21, 2005, 1:38 p.m.)
Deposited	1 year, 4 months ago (May 6, 2024, 12:20 p.m.)
Indexed	3 months ago (June 3, 2025, 12:28 p.m.)
Issued	20 years, 3 months ago (June 1, 2005)
Published	20 years, 3 months ago (June 1, 2005)
Published Print	20 years, 3 months ago (June 1, 2005)

Funders 0

None

BibTeX

@article{Reeve_2005, title={The Drosophila Fragile X Mental Retardation Protein Controls Actin Dynamics by Directly Regulating Profilin in the Brain}, volume={15}, ISSN={0960-9822}, url={http://dx.doi.org/10.1016/j.cub.2005.05.050}, DOI={10.1016/j.cub.2005.05.050}, number={12}, journal={Current Biology}, publisher={Elsevier BV}, author={Reeve, Simon P. and Bassetto, Laura and Genova, Ginka K. and Kleyner, Yelena and Leyssen, Maarten and Jackson, F. Rob and Hassan, Bassem A.}, year={2005}, month=jun, pages={1156–1163} }

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