DOI: 10.1016/j.cub.2004.07.051. Proteomic, Functional, and Domain-Based Analysis of In Vivo 14-3-3 Binding Proteins Involved in Cytoskeletal Regulation and Cellular Organization

Proteomic, Functional, and Domain-Based Analysis of In Vivo 14-3-3 Binding Proteins Involved in Cytoskeletal Regulation and Cellular Organization

10.1016/j.cub.2004.07.051

Crossref journal-article

Elsevier BV

Current Biology (78)

Bibliography

Jin, J., Smith, F. D., Stark, C., Wells, C. D., Fawcett, J. P., Kulkarni, S., Metalnikov, P., OâDonnell, P., Taylor, P., Taylor, L., Zougman, A., Woodgett, J. R., Langeberg, L. K., Scott, J. D., & Pawson, T. (2004). Proteomic, Functional, and Domain-Based Analysis of In Vivo 14-3-3 Binding Proteins Involved in Cytoskeletal Regulation and Cellular Organization. Current Biology, 14(16), 1436â1450.

Authors 15

Jing Jin (first)
F.Donelson Smith (additional)
Chris Stark (additional)
Clark D. Wells (additional)
James P. Fawcett (additional)
Sarang Kulkarni (additional)
Pavel Metalnikov (additional)
Paul O'Donnell (additional)
Paul Taylor (additional)
Lorne Taylor (additional)
Alexandre Zougman (additional)
James R. Woodgett (additional)
Lorene K. Langeberg (additional)
John D. Scott (additional)
Tony Pawson (additional)

References 55 Referenced 374

10.1016/S0092-8674(00)81688-8 / Cell / Signaling–2000 and beyond by Hunter (2000)
10.1126/science.1083653 / Science / Assembly of cell regulatory systems through protein interaction domains by Pawson (2003)
10.1016/S0092-8674(00)81067-3 / Cell / Interaction of 14–3–3 with signaling proteins is mediated by the recognition of phosphoserine by Muslin (1996)
10.1016/S0092-8674(00)80487-0 / Cell / The structural basis for 14–3–3:phosphopeptide binding specificity by Yaffe (1997)
10.1016/S0092-8674(01)00316-6 / Cell / Crystal structure of the 14–3–3ζ:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation by Obsil (2001)
10.1146/annurev.pharmtox.40.1.617 / Annu. Rev. Pharmacol. Toxicol. / 14–3–3 proteins by Fu (2000)
10.1016/S0014-5793(01)03288-4 / FEBS Lett. / How do 14–3–3 proteins work?–Gatekeeper phosphorylation and the molecular anvil hypothesis by Yaffe (2002)
10.1093/emboj/cdg363 / EMBO J. / 14–3–3s regulate fructose-2,6-bisphosphate levels by binding to PKB-phosphorylated cardiac fructose-2,6-bisphosphate kinase/phosphatase by Pozuelo Rubio (2003)
10.1016/S1534-5807(02)00320-9 / Dev. Cell / Drosophila 14–3–3/PAR-5 is an essential mediator of PAR-1 function in axis formation by Benton (2002)
10.1042/BJ20031332 / Biochem. J. / Dynamic interactions between 14–3–3s and phosphoproteins regulate diverse cellular processes by MacKintosh (2004)
10.1038/nrc1230 / Nat. Rev. Cancer / The 14–3–3 cancer connection by Hermeking (2003)
10.1016/S0092-8674(00)80405-5 / Cell / Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery by Datta (1997)
10.1016/S0092-8674(00)80595-4 / Cell / Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor by Brunet (1999)
10.1042/bj20031797 / Biochem. J. / 14–3–3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking by Rubio (2004)
Meek, S.E., Lane, W.S., and Piwnica-Worms, H. (2004). Comprehensive proteomic analysis of interphase and mitotic 14–3–3 binding proteins. J. Biol. Chem. Published online June 4. 10.1074/jbc.M403044200. (10.1074/jbc.M403044200)
10.1016/S0006-291X(02)02902-9 / Biochem. Biophys. Res. Commun. / Mammalian and yeast 14–3–3 isoforms form distinct patterns of dimers in vivo by Chaudhri (2003)
10.1021/bi991353h / Biochemistry / Isolation of high-affinity peptide antagonists of 14–3–3 proteins by phage display by Wang (1999)
10.1074/jbc.273.26.16305 / J. Biol. Chem. / 14–3–3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove by Petosa (1998)
10.1101/gr.180801 / Genome Res. / Creating the gene ontology resource by Gene Ontology Consortium (2001)
10.1093/nar/gkg584 / Nucleic Acids Res. / Scansite 2.0 by Obenauer (2003)
10.1073/pnas.95.25.14863 / Proc. Natl. Acad. Sci. USA / Cluster analysis and display of genome-wide expression patterns by Eisen (1998)
10.1016/S1097-2765(03)00246-6 / Mol. Cell / PB1 domain-mediated heterodimerization in NADPH oxidase and signaling complexes of atypical protein kinase C with Par6 and p62 by Wilson (2003)
10.1074/jbc.C300313200 / J. Biol. Chem. / PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway by Nakamura (2003)
10.1038/35019582 / Nat. Cell Biol. / A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity by Lin (2000)
10.1038/35019573 / Nat. Cell Biol. / The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42 by Joberty (2000)
10.1038/375554a0 / Nature / The 2.2 Å crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue by Nassar (1995)
10.1146/annurev.biochem.72.121801.161742 / Annu. Rev. Biochem. / Biology of the p21-activated kinases by Bokoch (2003)
10.1016/j.gde.2003.12.003 / Curr. Opin. Genet. Dev. / DNA damage tumor suppressor genes and genomic instability by Motoyama (2004)
10.1242/jcs.115.16.3275 / J. Cell Sci. / The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles by Mayor (2002)
10.1074/jbc.M910119199 / J. Biol. Chem. / The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase by Kisseleva (2000)
10.1006/geno.1999.5775 / Genomics / Human minibrain homologue (MNBH/DYRK1) by Guimera (1999)
10.1093/hmg/10.18.1915 / Hum. Mol. Genet. / Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome by Altafaj (2001)
10.1126/science.1062844 / Science / Human hypertension caused by mutations in WNK kinases by Wilson (2001)
10.1016/j.cub.2004.01.048 / Curr. Biol. / Par proteins by Macara (2004)
10.1016/S0092-8674(00)80844-2 / Cell / PARsing embryonic polarity by Kemphues (2000)
10.1016/S0092-8674(03)00938-3 / Cell / Drosophila PAR-1 and 14–3–3 inhibit Bazooka/PAR-3 to establish complementary cortical domains in polarized cells by Benton (2003)
10.1016/j.cub.2003.11.020 / Curr. Biol. / Phosphorylation-dependent binding of 14–3–3 to the polarity protein Par3 regulates cell polarity in mammalian epithelia by Hurd (2003)
10.1074/jbc.M312171200 / J. Biol. Chem. / Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network by Brajenovic (2004)
10.1038/nature01124 / Nature / Progenitor cell maintenance requires numb and numblike during mouse neurogenesis by Petersen (2002)
10.1093/hmg/4.3.373 / Hum. Mol. Genet. / Cloning of a human homologue of the Xenopus laevis APX gene from the ocular albinism type 1 critical region by Schiaffino (1995)
10.1074/jbc.M311946200 / J. Biol. Chem. / Characterization of Na+-permeable cation channels in LLC-PK1 renal epithelial cells by Raychowdhury (2004)
10.1038/nature00859 / Nature / Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck by Eden (2002)
10.1038/ncb1105 / Nat. Cell Biol. / Abi1 is essential for the formation and activation of a WAVE2 signalling complex by Innocenti (2004)
10.1016/S0960-9822(01)00506-1 / Curr. Biol. / Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex by Krugmann (2001)
10.1038/35047107 / Nature / IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling by Miki (2000)
10.1038/ncb886 / Nat. Cell Biol. / The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling by Soderling (2002)
10.1016/S0955-0674(03)00105-4 / Curr. Opin. Cell Biol. / Illuminating adhesion complexes in migrating cells by Webb (2003)
10.1128/JVI.72.2.1235-1243.1998 / J. Virol. / Virus-induced cell motility by Sanderson (1998)
10.1146/annurev.micro.57.030502.091037 / Annu. Rev. Microbiol. / Vaccinia virus motility by Smith (2003)
10.1146/annurev.pharmtox.42.083101.135801 / Annu. Rev. Pharmacol. Toxicol. / AKAP mediated signal transduction by Michel (2002)
10.1242/jcs.114.8.1431 / J. Cell Sci. / AKAP signaling complexes at the cytoskeleton by Diviani (2001)
10.1073/pnas.0330734100 / Proc. Natl. Acad. Sci. USA / Bioinformatic design of A-kinase anchoring protein-in silico by Alto (2003)
10.1074/jbc.M106629200 / J. Biol. Chem. / AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation by Diviani (2001)
{'key': '10.1016/j.cub.2004.07.051_BIB54', 'article-title': 'AKAP-Lbc nucleates a protein kinase D activation scaffold', 'volume': 'in press', 'author': 'Carnegie', 'year': '2004', 'journal-title': 'Mol. Cell'} / Mol. Cell / AKAP-Lbc nucleates a protein kinase D activation scaffold by Carnegie (2004)
10.1128/MCB.22.18.6582-6591.2002 / Mol. Cell. Biol. / Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells by Itoh (2002)

Dates

Type	When
Created	21 years ago (Aug. 27, 2004, 4:59 p.m.)
Deposited	1 year, 3 months ago (May 6, 2024, 12:01 p.m.)
Indexed	5 days, 13 hours ago (Aug. 23, 2025, 9:24 p.m.)
Issued	21 years ago (Aug. 1, 2004)
Published	21 years ago (Aug. 1, 2004)
Published Print	21 years ago (Aug. 1, 2004)

Funders 4

Howard Hughes Medical Institute 10.13039/100000011
Region: Americas
pri (Research institutes and centers)
Labels2
1. Howard Hughes Medical Institute Inc
2. HHMI
Genome Canada 10.13039/100008762
Region: Americas
pri (Other non-profit organizations)
Labels2
1. Génome Canada
2. GC
National Institutes of Health 10.13039/100000002
Region: Americas
gov (National government)
Labels3
1. Institutos Nacionales de la Salud
2. US National Institutes of Health
3. NIH
Awards1
1. DK44239
Canadian Institutes of Health Research 10.13039/501100000024
Region: Americas
gov (National government)
Labels6
1. Instituts de Recherche en Santé du Canada
2. Canadian Institutes of Health Research (CIHR)
3. CIHR_IRSC
4. Canadian Institutes of Health Research | Ottawa ON
5. CIHR
6. IRSC

BibTeX

@article{Jin_2004, title={Proteomic, Functional, and Domain-Based Analysis of In Vivo 14-3-3 Binding Proteins Involved in Cytoskeletal Regulation and Cellular Organization}, volume={14}, ISSN={0960-9822}, url={http://dx.doi.org/10.1016/j.cub.2004.07.051}, DOI={10.1016/j.cub.2004.07.051}, number={16}, journal={Current Biology}, publisher={Elsevier BV}, author={Jin, Jing and Smith, F.Donelson and Stark, Chris and Wells, Clark D. and Fawcett, James P. and Kulkarni, Sarang and Metalnikov, Pavel and O’Donnell, Paul and Taylor, Paul and Taylor, Lorne and Zougman, Alexandre and Woodgett, James R. and Langeberg, Lorene K. and Scott, John D. and Pawson, Tony}, year={2004}, month=aug, pages={1436–1450} }

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      "author": "Fu",
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      "volume": "513",
      "author": "Yaffe",
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      "author": "Pozuelo Rubio",
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      "DOI": "10.1016/S0092-8674(00)80405-5",
      "article-title": "Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery",
      "volume": "91",
      "author": "Datta",
      "year": "1997",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "857",
      "DOI": "10.1016/S0092-8674(00)80595-4",
      "article-title": "Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor",
      "volume": "96",
      "author": "Brunet",
      "year": "1999",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "395",
      "DOI": "10.1042/bj20031797",
      "article-title": "14\u20133\u20133-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking",
      "volume": "379",
      "author": "Rubio",
      "year": "2004",
      "journal-title": "Biochem. J."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB15",
      "doi-asserted-by": "crossref",
      "unstructured": "Meek, S.E., Lane, W.S., and Piwnica-Worms, H. (2004). Comprehensive proteomic analysis of interphase and mitotic 14\u20133\u20133 binding proteins. J. Biol. Chem. Published online June 4. 10.1074/jbc.M403044200.",
      "DOI": "10.1074/jbc.M403044200"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "679",
      "DOI": "10.1016/S0006-291X(02)02902-9",
      "article-title": "Mammalian and yeast 14\u20133\u20133 isoforms form distinct patterns of dimers in vivo",
      "volume": "300",
      "author": "Chaudhri",
      "year": "2003",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "12499",
      "DOI": "10.1021/bi991353h",
      "article-title": "Isolation of high-affinity peptide antagonists of 14\u20133\u20133 proteins by phage display",
      "volume": "38",
      "author": "Wang",
      "year": "1999",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "16305",
      "DOI": "10.1074/jbc.273.26.16305",
      "article-title": "14\u20133\u20133zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove",
      "volume": "273",
      "author": "Petosa",
      "year": "1998",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "1425",
      "DOI": "10.1101/gr.180801",
      "article-title": "Creating the gene ontology resource",
      "volume": "11",
      "author": "Gene Ontology Consortium",
      "year": "2001",
      "journal-title": "Genome Res."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "3635",
      "DOI": "10.1093/nar/gkg584",
      "article-title": "Scansite 2.0",
      "volume": "31",
      "author": "Obenauer",
      "year": "2003",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "14863",
      "DOI": "10.1073/pnas.95.25.14863",
      "article-title": "Cluster analysis and display of genome-wide expression patterns",
      "volume": "95",
      "author": "Eisen",
      "year": "1998",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "39",
      "DOI": "10.1016/S1097-2765(03)00246-6",
      "article-title": "PB1 domain-mediated heterodimerization in NADPH oxidase and signaling complexes of atypical protein kinase C with Par6 and p62",
      "volume": "12",
      "author": "Wilson",
      "year": "2003",
      "journal-title": "Mol. Cell"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "36989",
      "DOI": "10.1074/jbc.C300313200",
      "article-title": "PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway",
      "volume": "278",
      "author": "Nakamura",
      "year": "2003",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "540",
      "DOI": "10.1038/35019582",
      "article-title": "A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity",
      "volume": "2",
      "author": "Lin",
      "year": "2000",
      "journal-title": "Nat. Cell Biol."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "531",
      "DOI": "10.1038/35019573",
      "article-title": "The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42",
      "volume": "2",
      "author": "Joberty",
      "year": "2000",
      "journal-title": "Nat. Cell Biol."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "554",
      "DOI": "10.1038/375554a0",
      "article-title": "The 2.2 \u00c5 crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue",
      "volume": "375",
      "author": "Nassar",
      "year": "1995",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "743",
      "DOI": "10.1146/annurev.biochem.72.121801.161742",
      "article-title": "Biology of the p21-activated kinases",
      "volume": "72",
      "author": "Bokoch",
      "year": "2003",
      "journal-title": "Annu. Rev. Biochem."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "11",
      "DOI": "10.1016/j.gde.2003.12.003",
      "article-title": "DNA damage tumor suppressor genes and genomic instability",
      "volume": "14",
      "author": "Motoyama",
      "year": "2004",
      "journal-title": "Curr. Opin. Genet. Dev."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "3275",
      "DOI": "10.1242/jcs.115.16.3275",
      "article-title": "The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles",
      "volume": "115",
      "author": "Mayor",
      "year": "2002",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "20110",
      "DOI": "10.1074/jbc.M910119199",
      "article-title": "The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase",
      "volume": "275",
      "author": "Kisseleva",
      "year": "2000",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "407",
      "DOI": "10.1006/geno.1999.5775",
      "article-title": "Human minibrain homologue (MNBH/DYRK1)",
      "volume": "57",
      "author": "Guimera",
      "year": "1999",
      "journal-title": "Genomics"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "1915",
      "DOI": "10.1093/hmg/10.18.1915",
      "article-title": "Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome",
      "volume": "10",
      "author": "Altafaj",
      "year": "2001",
      "journal-title": "Hum. Mol. Genet."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "1107",
      "DOI": "10.1126/science.1062844",
      "article-title": "Human hypertension caused by mutations in WNK kinases",
      "volume": "293",
      "author": "Wilson",
      "year": "2001",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "R160",
      "DOI": "10.1016/j.cub.2004.01.048",
      "article-title": "Par proteins",
      "volume": "14",
      "author": "Macara",
      "year": "2004",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "345",
      "DOI": "10.1016/S0092-8674(00)80844-2",
      "article-title": "PARsing embryonic polarity",
      "volume": "101",
      "author": "Kemphues",
      "year": "2000",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "691",
      "DOI": "10.1016/S0092-8674(03)00938-3",
      "article-title": "Drosophila PAR-1 and 14\u20133\u20133 inhibit Bazooka/PAR-3 to establish complementary cortical domains in polarized cells",
      "volume": "115",
      "author": "Benton",
      "year": "2003",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "2082",
      "DOI": "10.1016/j.cub.2003.11.020",
      "article-title": "Phosphorylation-dependent binding of 14\u20133\u20133 to the polarity protein Par3 regulates cell polarity in mammalian epithelia",
      "volume": "13",
      "author": "Hurd",
      "year": "2003",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "12804",
      "DOI": "10.1074/jbc.M312171200",
      "article-title": "Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network",
      "volume": "279",
      "author": "Brajenovic",
      "year": "2004",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "929",
      "DOI": "10.1038/nature01124",
      "article-title": "Progenitor cell maintenance requires numb and numblike during mouse neurogenesis",
      "volume": "419",
      "author": "Petersen",
      "year": "2002",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "373",
      "DOI": "10.1093/hmg/4.3.373",
      "article-title": "Cloning of a human homologue of the Xenopus laevis APX gene from the ocular albinism type 1 critical region",
      "volume": "4",
      "author": "Schiaffino",
      "year": "1995",
      "journal-title": "Hum. Mol. Genet."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "20137",
      "DOI": "10.1074/jbc.M311946200",
      "article-title": "Characterization of Na+-permeable cation channels in LLC-PK1 renal epithelial cells",
      "volume": "279",
      "author": "Raychowdhury",
      "year": "2004",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "790",
      "DOI": "10.1038/nature00859",
      "article-title": "Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck",
      "volume": "418",
      "author": "Eden",
      "year": "2002",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "319",
      "DOI": "10.1038/ncb1105",
      "article-title": "Abi1 is essential for the formation and activation of a WAVE2 signalling complex",
      "volume": "6",
      "author": "Innocenti",
      "year": "2004",
      "journal-title": "Nat. Cell Biol."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "1645",
      "DOI": "10.1016/S0960-9822(01)00506-1",
      "article-title": "Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex",
      "volume": "11",
      "author": "Krugmann",
      "year": "2001",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "732",
      "DOI": "10.1038/35047107",
      "article-title": "IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling",
      "volume": "408",
      "author": "Miki",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "970",
      "DOI": "10.1038/ncb886",
      "article-title": "The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling",
      "volume": "4",
      "author": "Soderling",
      "year": "2002",
      "journal-title": "Nat. Cell Biol."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "614",
      "DOI": "10.1016/S0955-0674(03)00105-4",
      "article-title": "Illuminating adhesion complexes in migrating cells",
      "volume": "15",
      "author": "Webb",
      "year": "2003",
      "journal-title": "Curr. Opin. Cell Biol."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "1235",
      "DOI": "10.1128/JVI.72.2.1235-1243.1998",
      "article-title": "Virus-induced cell motility",
      "volume": "72",
      "author": "Sanderson",
      "year": "1998",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "323",
      "DOI": "10.1146/annurev.micro.57.030502.091037",
      "article-title": "Vaccinia virus motility",
      "volume": "57",
      "author": "Smith",
      "year": "2003",
      "journal-title": "Annu. Rev. Microbiol."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "235",
      "DOI": "10.1146/annurev.pharmtox.42.083101.135801",
      "article-title": "AKAP mediated signal transduction",
      "volume": "42",
      "author": "Michel",
      "year": "2002",
      "journal-title": "Annu. Rev. Pharmacol. Toxicol."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB51",
      "doi-asserted-by": "crossref",
      "first-page": "1431",
      "DOI": "10.1242/jcs.114.8.1431",
      "article-title": "AKAP signaling complexes at the cytoskeleton",
      "volume": "114",
      "author": "Diviani",
      "year": "2001",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB52",
      "doi-asserted-by": "crossref",
      "first-page": "4445",
      "DOI": "10.1073/pnas.0330734100",
      "article-title": "Bioinformatic design of A-kinase anchoring protein-in silico",
      "volume": "100",
      "author": "Alto",
      "year": "2003",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB53",
      "doi-asserted-by": "crossref",
      "first-page": "44247",
      "DOI": "10.1074/jbc.M106629200",
      "article-title": "AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation",
      "volume": "276",
      "author": "Diviani",
      "year": "2001",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB54",
      "article-title": "AKAP-Lbc nucleates a protein kinase D activation scaffold",
      "volume": "in press",
      "author": "Carnegie",
      "year": "2004",
      "journal-title": "Mol. Cell"
    },
    {
      "key": "10.1016/j.cub.2004.07.051_BIB55",
      "doi-asserted-by": "crossref",
      "first-page": "6582",
      "DOI": "10.1128/MCB.22.18.6582-6591.2002",
      "article-title": "Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells",
      "volume": "22",
      "author": "Itoh",
      "year": "2002",
      "journal-title": "Mol. Cell. Biol."
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