DOI: 10.1016/j.copbio.2004.10.005. Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs

Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs

10.1016/j.copbio.2004.10.005

Crossref journal-article

Elsevier BV

Current Opinion in Biotechnology (78)

Bibliography

Felnerova, D., Viret, J.-F., GlÃ¼ck, R., & Moser, C. (2004). Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs. Current Opinion in Biotechnology, 15(6), 518â529.

Authors 4

Diana Felnerova (first)
Jean-François Viret (additional)
Reinhard Glück (additional)
Christian Moser (additional)

References 88 Referenced 229

10.1038/2081295a0 / Nature / Cation permeability of phospholipid model membranes: effect of narcotics by Bangham (1965)
10.1038/252252a0 / Nature / Liposomes as immunological adjuvants by Allison (1974)
10.1172/JCI116141 / J Clin Invest / Immunopotentiating reconstituted influenza virus virosome vaccine delivery system for immunization against hepatitis A by Gluck (1992)
10.1586/14760584.2.2.189 / Expert Rev Vaccines / Virosomal adjuvanted antigen delivery systems by Moser (2003)
10.1016/S0264-410X(02)00540-6 / Vaccine / Liposomes and ISCOMs by Kersten (2003)
10.1016/S0168-3659(97)00261-7 / J Control Release / Development of liposomal anthracyclines: from basics to clinical applications by Gabizon (1998)
10.1016/S0163-7827(00)00011-4 / Prog Lipid Res / Current status of pH-sensitive liposomes in drug delivery by Drummond (2000)
10.1016/S0169-409X(01)00213-7 / Adv Drug Deliv Rev / Towards synthetic viruses by Zuber (2001)
10.2174/1381612043453009 / Curr Pharm Des / Current status of delivery systems to improve target efficacy of oligonucleotides by Shoji (2004)
10.2174/0929867033457421 / Curr Med Chem / Cationic liposomes as in vivo delivery vehicles by Templeton (2003)
10.1016/0009-3084(86)90066-6 / Chem Phys Lipids / Lipid polymorphism by Tilcock (1986)
{'key': '10.1016/j.copbio.2004.10.005_bib12', 'first-page': '123', 'article-title': 'Fate and behavior of liposomes in vivo: a review of controlling factors', 'volume': '3', 'author': 'Senior', 'year': '1987', 'journal-title': 'Crit Rev Ther Drug Carrier Syst'} / Crit Rev Ther Drug Carrier Syst / Fate and behavior of liposomes in vivo: a review of controlling factors by Senior (1987)
10.1016/0005-2736(92)90034-J / Biochim Biophys Acta / Some negatively charged phospholipid derivatives prolong the liposome circulation in vivo by Park (1992)
10.1016/0005-2736(92)90194-Q / Biochim Biophys Acta / Versatility in lipid compositions showing prolonged circulation with sterically stabilized liposomes by Woodle (1992)
10.1002/jgm.509 / J Gene Med / Physicochemical optimisation of plasmid delivery by cationic lipids by Tranchant (2004)
10.1021/ar9703241 / Acc Chem Res / Chemical approaches to triggerable lipid vesicles for drug and gene delivery by Guo (2003)
10.1021/bi00302a029 / Biochemistry / pH-induced destabilization of phosphatidylethanolamine-containing liposomes: role of bilayer contact by Ellens (1984)
10.1021/bc000110v / Bioconjug Chem / Steric stabilization of fusogenic liposomes by a low-pH sensitive PEG–diortho ester–lipid conjugate by Guo (2001)
10.1016/j.phrs.2003.09.003 / Pharmacol Res / Pharmaco attributes of dioleoylphosphatidylethanolamine/cholesterylhemisuccinate liposomes containing different types of cleavable lipopolymers by Zhang (2004)
10.1158/1078-0432.CCR-03-0035 / Clin Cancer Res / Novel temperature-sensitive liposomes with prolonged circulation time by Lindner (2004)
10.1016/S0169-409X(01)00233-2 / Adv Drug Deliv Rev / The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors by Needham (2001)
10.1081/LPR-120004777 / J Liposome Res / Targeted liposomes for delivery of protein-based drugs into the cytoplasm of tumor cells by Mastrobattista (2002)
10.1023/A:1020198908574 / Biosci Rep / Delivery of protein antigens to the immune system by fusion-active virosomes: a comparison with liposomes and ISCOMs by Bungener (2002)
10.1211/002235702928 / J Pharm Pharmacol / Enhancement of polyethylene glycol (PEG)-modified cationic liposome-mediated gene deliveries: effects on serum stability and transfection efficiency by Kim (2003)
10.1023/A:1020186505848 / Biosci Rep / Controlling the physical behavior and biological performance of liposome formulations through use of surface grafted poly(ethylene glycol) by Allen (2002)
10.1124/jpet.103.060228 / J Pharmacol Exp Ther / Neutral and anionic liposome-encapsulated hemoglobin: effect of postinserted poly(ethylene glycol) -distearoylphosphatidylethanolamine on distribution and circulation kinetics by Awasthi (2004)
10.1016/S0304-3835(03)00099-5 / Cancer Lett / Development of Fab’ fragments of anti-GD(2) immunoliposomes entrapping doxorubicin for experimental therapy of human neuroblastoma by Brignole (2003)
10.1016/S0163-7827(03)00032-8 / Prog Lipid Res / Ligand-targeted liposomal anticancer drugs by Sapra (2003)
10.1016/S0076-6879(03)72019-9 / Methods Enzymol / Tat peptide-mediated intracellular delivery of liposomes by Levchenko (2003)
10.1016/S0092-8674(00)81843-7 / Cell / Intercellular trafficking and protein delivery by a herpesvirus structural protein by Elliott (1997)
10.2174/1389203033487298 / Curr Protein Pept Sci / TAT-liposomes: a novel intracellular drug carrier by Torchilin (2003)
10.1186/1472-6750-2-9 / BMC Biotechnol / Protein encapsulation in liposomes: efficiency depends on interactions between protein and phospholipid bilayer by Colletier (2002)
10.1158/1078-0432.CCR-1131-03 / Clin Cancer Res / In vitro and in vivo characterization of doxorubicin and vincristine coencapsulated within liposomes through use of transition metal ion complexation and pH gradient loading by Abraham (2004)
{'key': '10.1016/j.copbio.2004.10.005_bib34', 'first-page': '439', 'article-title': 'Formulation kit for liposomal doxorubicin composed of lyophilized liposomes', 'volume': '23', 'author': 'Stevens', 'year': '2003', 'journal-title': 'Anticancer Res'} / Anticancer Res / Formulation kit for liposomal doxorubicin composed of lyophilized liposomes by Stevens (2003)
10.1016/S0076-6879(03)67003-5 / Methods Enzymol / Preparation and quantitation of small unilamellar liposomes and large unilamellar reverse-phase evaporation liposomes by Duzgunes (2003)
10.1073/pnas.1931005100 / Proc Natl Acad Sci USA / Engineering asymmetric vesicles by Pautot (2003)
10.1016/S0140-6736(75)92130-3 / Lancet / Formation of virosomes from influenza subunits and liposomes by Almeida (1975)
10.1016/S0264-410X(02)00541-8 / Vaccine / Immunostimulating reconstituted influenza virosomes by Zurbriggen (2003)
10.1111/j.1348-0421.2004.tb03502.x / Microbiol Immunol / Preparation of virosomes coated with the vesicular stomatitis virus glycoprotein as efficient gene transfer vehicles for animal cells by Shoji (2004)
10.1637/6082 / Avian Dis / Development of a virosome vaccine for Newcastle disease virus by Kapczynski (2003)
10.5483/BMBRep.2002.35.5.459 / J Biochem Mol Biol / Effect of lipid compositions on gene transfer into 293 cells using Sendai F/HN-virosomes by Kim (2002)
10.1016/S0264-410X(02)00567-4 / Vaccine / Novel approaches in the development of immunopotentiating reconstituted influenza virosomes as efficient antigen carrier systems by Gluck (2003)
{'key': '10.1016/j.copbio.2004.10.005_bib43', 'first-page': '437', 'article-title': 'Targeting her-2/neu with antirat Neu virosomes for cancer therapy', 'volume': '62', 'author': 'Waelti', 'year': '2002', 'journal-title': 'Cancer Res'} / Cancer Res / Targeting her-2/neu with antirat Neu virosomes for cancer therapy by Waelti (2002)
10.1016/S0264-410X(02)00542-X / Vaccine / Influenza virosomes: combining optimal presentation of hemagglutinin with immunopotentiating activity by Huckriede (2003)
10.1002/eji.1830251236 / Eur J Immunol / T helper cell-independent neutralizing B cell response against vesicular stomatitis virus: role of antigen patterns in B cell induction? by Bachmann (1995)
10.1016/j.vaccine.2003.08.019 / Vaccine / Influenza virosomes enhance class I restricted CTL induction through CD4+ T cell activation by Schumacher (2004)
10.1016/S0264-410X(02)00512-1 / Vaccine / Inflexal V a trivalent virosome subunit influenza vaccine: production by Mischler (2002)
10.1016/S0163-7827(99)00017-X / Prog Lipid Res / IRIV-adjuvanted hepatitis A vaccine: in vivo absorption and biophysical characterization by Zurbriggen (2000)
10.1172/JCI116141 / J Clin Invest / Immunopotentiating reconstituted influenza virus virosome vaccine delivery system for immunization against hepatitis A by Gluck (1992)
10.1128/IAI.71.8.4749-4758.2003 / Infect Immun / Induction of parasite growth-inhibitory antibodies by a virosomal formulation of a peptidomimetic of loop I from domain III of Plasmodium falciparum apical membrane antigen 1 by Mueller (2003)
10.1093/intimm/dxf026 / Int Immunol / In vitro studies of core peptide-bearing immunopotentiating reconstituted influenza virosomes as a non-live prototype vaccine against hepatitis C virus by Hunziker (2002)
10.1016/S0264-410X(02)00353-5 / Vaccine / Influenza virosomes are an efficient delivery system for respiratory syncytial virus-F antigen inducing humoral and cell-mediated immunity by Cusi (2002)
10.1016/S0959-8049(01)00241-6 / Eur J Cancer / Tumour-associated antigen (TAA)-specific cytotoxic T cell (CTL) response in vitro and in a mouse model, induced by TAA-plasmids delivered by influenza virosomes by Correale (2001)
10.1002/(SICI)1097-0215(19980831)77:5<728::AID-IJC11>3.0.CO;2-Y / Int J Cancer / Delivery to cancer cells of antisense L-myc oligonucleotides incorporated in fusogenic, cationic-lipid-reconstituted influenza-virus envelopes (cationic virosomes) by Waelti (1998)
10.1016/S0168-1702(00)00254-9 / Virus Res / Localization of a new neutralizing epitope on the mumps virus hemagglutinin–neuraminidase protein by Cusi (2001)
10.1038/sj.bjc.6601028 / Br J Cancer / In vivo study of the GC90/IRIV vaccine for immune response and autoimmunity into a novel humanised transgenic mouse by Scardino (2003)
{'key': '10.1016/j.copbio.2004.10.005_bib57', 'first-page': '253', 'article-title': 'Engineered liposomes for potential α-particle therapy of metastatic cancer', 'volume': '45', 'author': 'Sofou', 'year': '2004', 'journal-title': 'J Nucl Med'} / J Nucl Med / Engineered liposomes for potential α-particle therapy of metastatic cancer by Sofou (2004)
10.1081/LPR-120017485 / J Liposome Res / Anti-neovascular therapy by use of liposomes targeted to angiogenic vessels by Oku (2003)
10.1002/jbm.a.20235 / J Biomed Mater Res / Pentapeptide YIGSR-mediated HT-1080 fibrosarcoma cells targeting of adriamycin encapsulated in sterically stabilized liposomes by Lopez-Barcons (2004)
10.1038/sj.bjc.6601341 / Br J Cancer / Efficacy of immunoliposomes on cancer models in a cell-surface-antigen-density-dependent manner by Hosokawa (2003)
10.1158/1078-0432.CCR-03-0376 / Clin Cancer Res / Improved outcome when B-cell lymphoma is treated with combinations of immunoliposomal anticancer drugs targeted to both the CD19 and CD20 epitopes by Sapra (2004)
10.1177/002215540305100915 / J Histochem Cytochem / Intravenous liposomal prednisolone downregulates in situ TNF-α production by T-cells in experimental autoimmune encephalomyelitis by Schmidt (2003)
10.1182/blood-2001-11-0061 / Blood / Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model by Jordan (2003)
10.1023/A:1025057216492 / Pharm Res / Targeting and blocking B7 costimulatory molecules on antigen-presenting cells using CTLA4Ig-conjugated liposomes: in vitro characterization and in vivo factors affecting biodistribution by Park (2003)
10.1002/art.11140 / Arthritis Rheum / Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes by Metselaar (2003)
10.1067/mai.2003.104 / J Allergy Clin Immunol / Efficacy of liposomal budesonide in experimental asthma by Konduri (2003)
10.1046/j.1365-2133.2002.04800.x / Br J Dermatol / Liposomal tacrolimus lotion as a novel topical agent for treatment of immune-mediated skin disorders: experimental studies in a murine model by Erdogan (2002)
10.1081/DDC-120025872 / Drug Dev Ind Pharm / Continuous release of interleukin-2 from liposomal IL-2 (mixture of interleukin-2 and liposomes) after subcutaneous administration to mice by Kanaoka (2003)
10.1093/jac/48.3.333 / J Antimicrob Chemother / Liposome-encapsulated aminoglycosides in pre-clinical and clinical studies by Schiffelers (2001)
10.1080/1042819031000099733 / Leuk Lymphoma / Cellular pharmacology of P-ethoxy antisense oligonucleotides targeted to Bcl-2 in a follicular lymphoma cell line by Gutierrez-Puente (2003)
10.1016/S0168-3659(02)00484-4 / J Control Release / Remarkable induction of apoptosis in cancer cells by a novel cationic liposome complexed with a bcl-2 antisense oligonucleotide by Noguchi (2003)
10.1007/s00262-003-0416-5 / Cancer Immunol Immunother / Antitumor effects of combined therapy of recombinant heat shock protein 70 and hyperthermia using magnetic nanoparticles in an experimental subcutaneous murine melanoma by Ito (2004)
10.4161/cbt.3.2.622 / Cancer Biol Ther / Pharmacodynamic behavior of liposomal antisense oligonucleotides targeting Her-2/neu and vascular endothelial growth factor in an ascitic MDA435/LCC6 human breast cancer model by Waterhouse (2004)
10.1016/S0304-3835(03)00107-1 / Cancer Lett / Targeted delivery system for antisense oligonucleotides: a novel experimental strategy for neuroblastoma treatment by Brignole (2003)
10.1089/10430340460732472 / Hum Gene Ther / Human gene therapy for malignant gliomas (glioblastoma multiforme and anaplastic astrocytoma) by in vivo transduction with human interferon β gene using cationic liposomes by Yoshida (2004)
10.1016/S0966-3274(03)00002-9 / Transpl Immunol / Genetic modification of cold-preserved renal grafts using HSP70 or bcl-2 HVJ-liposome method by Kita (2003)
{'key': '10.1016/j.copbio.2004.10.005_bib77', 'first-page': '552', 'article-title': 'Antisense oligonucleotides to Syk kinase: a novel therapeutic approach for respiratory disorders', 'volume': '4', 'author': 'Ulanova', 'year': '2003', 'journal-title': 'Curr Opin Investig Drugs'} / Curr Opin Investig Drugs / Antisense oligonucleotides to Syk kinase: a novel therapeutic approach for respiratory disorders by Ulanova (2003)
10.1021/bc034134o / Bioconjug Chem / Liposomes with differential lipid components exert differential adjuvanticity in antigen-liposome conjugates via differential recognition by macrophages by Tanaka (2004)
10.1016/S0264-410X(03)00172-5 / Vaccine / Effective induction of CD8+ T-cell response using CpG oligodeoxynucleotides and HER-2/neu-derived peptide co-encapsulated in liposomes by Li (2003)
{'key': '10.1016/j.copbio.2004.10.005_bib80', 'first-page': '465', 'article-title': 'Organ-specific gene expression in the rhesus monkey eye following intravenous non-viral gene transfer', 'volume': '9', 'author': 'Zhang', 'year': '2003', 'journal-title': 'Mol Vis'} / Mol Vis / Organ-specific gene expression in the rhesus monkey eye following intravenous non-viral gene transfer by Zhang (2003)
10.1016/S0264-410X(03)00042-2 / Vaccine / The domain III fragment of Japanese encephalitis virus envelope protein: mouse immunogenicity and liposome adjuvanticity by Wu (2003)
10.1089/104454904322759911 / DNA Cell Biol / Evaluation of genetic immunization adjuvants to improve the effectiveness of a human immunodeficiency virus type 2 (HIV-2) envelope DNA vaccine by Locher (2004)
10.1046/j.1365-2222.2002.01514.x / Clin Exp Allergy / Liposome-entrapped D. pteronyssinus vaccination in mild asthma patients: effect of 1-year double-blind, placebo-controlled trial on inflammation, bronchial hyperresponsiveness and immediate and late bronchial responses to the allergen by Alvarez (2002)
10.1016/j.vaccine.2003.09.030 / Vaccine / A mixed Th1/Th2 response elicited by a liposomal formulation of Leishmania vaccine instructs Th1 responses and resistance to Leishmania donovani in susceptible BALB/c mice by Mazumdar (2004)
10.1016/S0264-410X(98)00361-2 / Vaccine / Immunogenicity of IRIV — versus alum-adjuvanted diphtheria and tetanus toxoid vaccines in influenza primed mice by Zurbriggen (1999)
10.1016/S0014-5793(01)03112-X / FEBS Lett / Targeting influenza virosomes to ovarian carcinoma cells by Mastrobattista (2001)
10.1080/02652040010019550 / J Microencapsul / Enhanced cytotoxicity of doxorubicin encapsulated in liposomes with reconstituted Sendai F-proteins by Cho (2001)
10.1089/aid.1992.8.1823 / AIDS Res Hum Retroviruses / Properties of HIV membrane reconstituted from its recombinant gp160 envelope glycoprotein by Cornet (1992)

Dates

Type	When
Created	20 years, 10 months ago (Nov. 3, 2004, 7:09 a.m.)
Deposited	6 years, 7 months ago (Feb. 2, 2019, 3:51 a.m.)
Indexed	5 days, 20 hours ago (Aug. 29, 2025, 6:26 a.m.)
Issued	20 years, 9 months ago (Dec. 1, 2004)
Published	20 years, 9 months ago (Dec. 1, 2004)
Published Print	20 years, 9 months ago (Dec. 1, 2004)

Funders 0

None

BibTeX

@article{Felnerova_2004, title={Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs}, volume={15}, ISSN={0958-1669}, url={http://dx.doi.org/10.1016/j.copbio.2004.10.005}, DOI={10.1016/j.copbio.2004.10.005}, number={6}, journal={Current Opinion in Biotechnology}, publisher={Elsevier BV}, author={Felnerova, Diana and Viret, Jean-François and Glück, Reinhard and Moser, Christian}, year={2004}, month=dec, pages={518–529} }

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      "key": "10.1016/j.copbio.2004.10.005_bib17",
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      "first-page": "1532",
      "DOI": "10.1021/bi00302a029",
      "article-title": "pH-induced destabilization of phosphatidylethanolamine-containing liposomes: role of bilayer contact",
      "volume": "23",
      "author": "Ellens",
      "year": "1984",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "291",
      "DOI": "10.1021/bc000110v",
      "article-title": "Steric stabilization of fusogenic liposomes by a low-pH sensitive PEG\u2013diortho ester\u2013lipid conjugate",
      "volume": "12",
      "author": "Guo",
      "year": "2001",
      "journal-title": "Bioconjug Chem"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "185",
      "DOI": "10.1016/j.phrs.2003.09.003",
      "article-title": "Pharmaco attributes of dioleoylphosphatidylethanolamine/cholesterylhemisuccinate liposomes containing different types of cleavable lipopolymers",
      "volume": "49",
      "author": "Zhang",
      "year": "2004",
      "journal-title": "Pharmacol Res"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "2168",
      "DOI": "10.1158/1078-0432.CCR-03-0035",
      "article-title": "Novel temperature-sensitive liposomes with prolonged circulation time",
      "volume": "10",
      "author": "Lindner",
      "year": "2004",
      "journal-title": "Clin Cancer Res"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "285",
      "DOI": "10.1016/S0169-409X(01)00233-2",
      "article-title": "The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors",
      "volume": "53",
      "author": "Needham",
      "year": "2001",
      "journal-title": "Adv Drug Deliv Rev"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "57",
      "DOI": "10.1081/LPR-120004777",
      "article-title": "Targeted liposomes for delivery of protein-based drugs into the cytoplasm of tumor cells",
      "volume": "12",
      "author": "Mastrobattista",
      "year": "2002",
      "journal-title": "J Liposome Res"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib23_1",
      "doi-asserted-by": "crossref",
      "first-page": "323",
      "DOI": "10.1023/A:1020198908574",
      "article-title": "Delivery of protein antigens to the immune system by fusion-active virosomes: a comparison with liposomes and ISCOMs",
      "volume": "22",
      "author": "Bungener",
      "year": "2002",
      "journal-title": "Biosci Rep"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "453",
      "DOI": "10.1211/002235702928",
      "article-title": "Enhancement of polyethylene glycol (PEG)-modified cationic liposome-mediated gene deliveries: effects on serum stability and transfection efficiency",
      "volume": "55",
      "author": "Kim",
      "year": "2003",
      "journal-title": "J Pharm Pharmacol"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "225",
      "DOI": "10.1023/A:1020186505848",
      "article-title": "Controlling the physical behavior and biological performance of liposome formulations through use of surface grafted poly(ethylene glycol)",
      "volume": "22",
      "author": "Allen",
      "year": "2002",
      "journal-title": "Biosci Rep"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "241",
      "DOI": "10.1124/jpet.103.060228",
      "article-title": "Neutral and anionic liposome-encapsulated hemoglobin: effect of postinserted poly(ethylene glycol) -distearoylphosphatidylethanolamine on distribution and circulation kinetics",
      "volume": "309",
      "author": "Awasthi",
      "year": "2004",
      "journal-title": "J Pharmacol Exp Ther"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "199",
      "DOI": "10.1016/S0304-3835(03)00099-5",
      "article-title": "Development of Fab\u2019 fragments of anti-GD(2) immunoliposomes entrapping doxorubicin for experimental therapy of human neuroblastoma",
      "volume": "197",
      "author": "Brignole",
      "year": "2003",
      "journal-title": "Cancer Lett"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib28_1",
      "doi-asserted-by": "crossref",
      "first-page": "439",
      "DOI": "10.1016/S0163-7827(03)00032-8",
      "article-title": "Ligand-targeted liposomal anticancer drugs",
      "volume": "42",
      "author": "Sapra",
      "year": "2003",
      "journal-title": "Prog Lipid Res"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "339",
      "DOI": "10.1016/S0076-6879(03)72019-9",
      "article-title": "Tat peptide-mediated intracellular delivery of liposomes",
      "volume": "372",
      "author": "Levchenko",
      "year": "2003",
      "journal-title": "Methods Enzymol"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "223",
      "DOI": "10.1016/S0092-8674(00)81843-7",
      "article-title": "Intercellular trafficking and protein delivery by a herpesvirus structural protein",
      "volume": "88",
      "author": "Elliott",
      "year": "1997",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "133",
      "DOI": "10.2174/1389203033487298",
      "article-title": "TAT-liposomes: a novel intracellular drug carrier",
      "volume": "4",
      "author": "Torchilin",
      "year": "2003",
      "journal-title": "Curr Protein Pept Sci"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "9",
      "DOI": "10.1186/1472-6750-2-9",
      "article-title": "Protein encapsulation in liposomes: efficiency depends on interactions between protein and phospholipid bilayer",
      "volume": "2",
      "author": "Colletier",
      "year": "2002",
      "journal-title": "BMC Biotechnol"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "728",
      "DOI": "10.1158/1078-0432.CCR-1131-03",
      "article-title": "In vitro and in vivo characterization of doxorubicin and vincristine coencapsulated within liposomes through use of transition metal ion complexation and pH gradient loading",
      "volume": "10",
      "author": "Abraham",
      "year": "2004",
      "journal-title": "Clin Cancer Res"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib34",
      "first-page": "439",
      "article-title": "Formulation kit for liposomal doxorubicin composed of lyophilized liposomes",
      "volume": "23",
      "author": "Stevens",
      "year": "2003",
      "journal-title": "Anticancer Res"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "23",
      "DOI": "10.1016/S0076-6879(03)67003-5",
      "article-title": "Preparation and quantitation of small unilamellar liposomes and large unilamellar reverse-phase evaporation liposomes",
      "volume": "367",
      "author": "Duzgunes",
      "year": "2003",
      "journal-title": "Methods Enzymol"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "10718",
      "DOI": "10.1073/pnas.1931005100",
      "article-title": "Engineering asymmetric vesicles",
      "volume": "100",
      "author": "Pautot",
      "year": "2003",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib37",
      "doi-asserted-by": "crossref",
      "first-page": "899",
      "DOI": "10.1016/S0140-6736(75)92130-3",
      "article-title": "Formation of virosomes from influenza subunits and liposomes",
      "volume": "2",
      "author": "Almeida",
      "year": "1975",
      "journal-title": "Lancet"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib38",
      "doi-asserted-by": "crossref",
      "first-page": "921",
      "DOI": "10.1016/S0264-410X(02)00541-8",
      "article-title": "Immunostimulating reconstituted influenza virosomes",
      "volume": "21",
      "author": "Zurbriggen",
      "year": "2003",
      "journal-title": "Vaccine"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib39",
      "doi-asserted-by": "crossref",
      "first-page": "163",
      "DOI": "10.1111/j.1348-0421.2004.tb03502.x",
      "article-title": "Preparation of virosomes coated with the vesicular stomatitis virus glycoprotein as efficient gene transfer vehicles for animal cells",
      "volume": "48",
      "author": "Shoji",
      "year": "2004",
      "journal-title": "Microbiol Immunol"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib40",
      "doi-asserted-by": "crossref",
      "first-page": "578",
      "DOI": "10.1637/6082",
      "article-title": "Development of a virosome vaccine for Newcastle disease virus",
      "volume": "47",
      "author": "Kapczynski",
      "year": "2003",
      "journal-title": "Avian Dis"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib41",
      "doi-asserted-by": "crossref",
      "first-page": "459",
      "DOI": "10.5483/BMBRep.2002.35.5.459",
      "article-title": "Effect of lipid compositions on gene transfer into 293 cells using Sendai F/HN-virosomes",
      "volume": "35",
      "author": "Kim",
      "year": "2002",
      "journal-title": "J Biochem Mol Biol"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib42",
      "doi-asserted-by": "crossref",
      "first-page": "611",
      "DOI": "10.1016/S0264-410X(02)00567-4",
      "article-title": "Novel approaches in the development of immunopotentiating reconstituted influenza virosomes as efficient antigen carrier systems",
      "volume": "21",
      "author": "Gluck",
      "year": "2003",
      "journal-title": "Vaccine"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib43",
      "first-page": "437",
      "article-title": "Targeting her-2/neu with antirat Neu virosomes for cancer therapy",
      "volume": "62",
      "author": "Waelti",
      "year": "2002",
      "journal-title": "Cancer Res"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib44",
      "doi-asserted-by": "crossref",
      "first-page": "925",
      "DOI": "10.1016/S0264-410X(02)00542-X",
      "article-title": "Influenza virosomes: combining optimal presentation of hemagglutinin with immunopotentiating activity",
      "volume": "21",
      "author": "Huckriede",
      "year": "2003",
      "journal-title": "Vaccine"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib45",
      "doi-asserted-by": "crossref",
      "first-page": "3445",
      "DOI": "10.1002/eji.1830251236",
      "article-title": "T helper cell-independent neutralizing B cell response against vesicular stomatitis virus: role of antigen patterns in B cell induction?",
      "volume": "25",
      "author": "Bachmann",
      "year": "1995",
      "journal-title": "Eur J Immunol"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib46",
      "doi-asserted-by": "crossref",
      "first-page": "714",
      "DOI": "10.1016/j.vaccine.2003.08.019",
      "article-title": "Influenza virosomes enhance class I restricted CTL induction through CD4+ T cell activation",
      "volume": "22",
      "author": "Schumacher",
      "year": "2004",
      "journal-title": "Vaccine"
    },
    {
      "issue": "Suppl 5",
      "key": "10.1016/j.copbio.2004.10.005_bib47",
      "doi-asserted-by": "crossref",
      "first-page": "B17",
      "DOI": "10.1016/S0264-410X(02)00512-1",
      "article-title": "Inflexal V a trivalent virosome subunit influenza vaccine: production",
      "volume": "20",
      "author": "Mischler",
      "year": "2002",
      "journal-title": "Vaccine"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib48",
      "doi-asserted-by": "crossref",
      "first-page": "3",
      "DOI": "10.1016/S0163-7827(99)00017-X",
      "article-title": "IRIV-adjuvanted hepatitis A vaccine: in vivo absorption and biophysical characterization",
      "volume": "39",
      "author": "Zurbriggen",
      "year": "2000",
      "journal-title": "Prog Lipid Res"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib49",
      "doi-asserted-by": "crossref",
      "first-page": "2491",
      "DOI": "10.1172/JCI116141",
      "article-title": "Immunopotentiating reconstituted influenza virus virosome vaccine delivery system for immunization against hepatitis A",
      "volume": "90",
      "author": "Gluck",
      "year": "1992",
      "journal-title": "J Clin Invest"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib50",
      "doi-asserted-by": "crossref",
      "first-page": "4749",
      "DOI": "10.1128/IAI.71.8.4749-4758.2003",
      "article-title": "Induction of parasite growth-inhibitory antibodies by a virosomal formulation of a peptidomimetic of loop I from domain III of Plasmodium falciparum apical membrane antigen 1",
      "volume": "71",
      "author": "Mueller",
      "year": "2003",
      "journal-title": "Infect Immun"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib51",
      "doi-asserted-by": "crossref",
      "first-page": "615",
      "DOI": "10.1093/intimm/dxf026",
      "article-title": "In vitro studies of core peptide-bearing immunopotentiating reconstituted influenza virosomes as a non-live prototype vaccine against hepatitis C virus",
      "volume": "14",
      "author": "Hunziker",
      "year": "2002",
      "journal-title": "Int Immunol"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib52",
      "doi-asserted-by": "crossref",
      "first-page": "3436",
      "DOI": "10.1016/S0264-410X(02)00353-5",
      "article-title": "Influenza virosomes are an efficient delivery system for respiratory syncytial virus-F antigen inducing humoral and cell-mediated immunity",
      "volume": "20",
      "author": "Cusi",
      "year": "2002",
      "journal-title": "Vaccine"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib53",
      "doi-asserted-by": "crossref",
      "first-page": "2097",
      "DOI": "10.1016/S0959-8049(01)00241-6",
      "article-title": "Tumour-associated antigen (TAA)-specific cytotoxic T cell (CTL) response in vitro and in a mouse model, induced by TAA-plasmids delivered by influenza virosomes",
      "volume": "37",
      "author": "Correale",
      "year": "2001",
      "journal-title": "Eur J Cancer"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib54",
      "doi-asserted-by": "crossref",
      "first-page": "728",
      "DOI": "10.1002/(SICI)1097-0215(19980831)77:5<728::AID-IJC11>3.0.CO;2-Y",
      "article-title": "Delivery to cancer cells of antisense L-myc oligonucleotides incorporated in fusogenic, cationic-lipid-reconstituted influenza-virus envelopes (cationic virosomes)",
      "volume": "77",
      "author": "Waelti",
      "year": "1998",
      "journal-title": "Int J Cancer"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib55",
      "doi-asserted-by": "crossref",
      "first-page": "133",
      "DOI": "10.1016/S0168-1702(00)00254-9",
      "article-title": "Localization of a new neutralizing epitope on the mumps virus hemagglutinin\u2013neuraminidase protein",
      "volume": "74",
      "author": "Cusi",
      "year": "2001",
      "journal-title": "Virus Res"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib56",
      "doi-asserted-by": "crossref",
      "first-page": "199",
      "DOI": "10.1038/sj.bjc.6601028",
      "article-title": "In vivo study of the GC90/IRIV vaccine for immune response and autoimmunity into a novel humanised transgenic mouse",
      "volume": "89",
      "author": "Scardino",
      "year": "2003",
      "journal-title": "Br J Cancer"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib57",
      "first-page": "253",
      "article-title": "Engineered liposomes for potential \u03b1-particle therapy of metastatic cancer",
      "volume": "45",
      "author": "Sofou",
      "year": "2004",
      "journal-title": "J Nucl Med"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib58",
      "doi-asserted-by": "crossref",
      "first-page": "25",
      "DOI": "10.1081/LPR-120017485",
      "article-title": "Anti-neovascular therapy by use of liposomes targeted to angiogenic vessels",
      "volume": "13",
      "author": "Oku",
      "year": "2003",
      "journal-title": "J Liposome Res"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib59",
      "doi-asserted-by": "crossref",
      "first-page": "155",
      "DOI": "10.1002/jbm.a.20235",
      "article-title": "Pentapeptide YIGSR-mediated HT-1080 fibrosarcoma cells targeting of adriamycin encapsulated in sterically stabilized liposomes",
      "volume": "69A",
      "author": "Lopez-Barcons",
      "year": "2004",
      "journal-title": "J Biomed Mater Res"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib60",
      "doi-asserted-by": "crossref",
      "first-page": "1545",
      "DOI": "10.1038/sj.bjc.6601341",
      "article-title": "Efficacy of immunoliposomes on cancer models in a cell-surface-antigen-density-dependent manner",
      "volume": "89",
      "author": "Hosokawa",
      "year": "2003",
      "journal-title": "Br J Cancer"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib61",
      "doi-asserted-by": "crossref",
      "first-page": "2530",
      "DOI": "10.1158/1078-0432.CCR-03-0376",
      "article-title": "Improved outcome when B-cell lymphoma is treated with combinations of immunoliposomal anticancer drugs targeted to both the CD19 and CD20 epitopes",
      "volume": "10",
      "author": "Sapra",
      "year": "2004",
      "journal-title": "Clin Cancer Res"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib62",
      "doi-asserted-by": "crossref",
      "first-page": "1241",
      "DOI": "10.1177/002215540305100915",
      "article-title": "Intravenous liposomal prednisolone downregulates in situ TNF-\u03b1 production by T-cells in experimental autoimmune encephalomyelitis",
      "volume": "51",
      "author": "Schmidt",
      "year": "2003",
      "journal-title": "J Histochem Cytochem"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib63",
      "doi-asserted-by": "crossref",
      "first-page": "594",
      "DOI": "10.1182/blood-2001-11-0061",
      "article-title": "Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model",
      "volume": "101",
      "author": "Jordan",
      "year": "2003",
      "journal-title": "Blood"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib64",
      "doi-asserted-by": "crossref",
      "first-page": "1239",
      "DOI": "10.1023/A:1025057216492",
      "article-title": "Targeting and blocking B7 costimulatory molecules on antigen-presenting cells using CTLA4Ig-conjugated liposomes: in vitro characterization and in vivo factors affecting biodistribution",
      "volume": "20",
      "author": "Park",
      "year": "2003",
      "journal-title": "Pharm Res"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib65",
      "doi-asserted-by": "crossref",
      "first-page": "2059",
      "DOI": "10.1002/art.11140",
      "article-title": "Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes",
      "volume": "48",
      "author": "Metselaar",
      "year": "2003",
      "journal-title": "Arthritis Rheum"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib66",
      "doi-asserted-by": "crossref",
      "first-page": "321",
      "DOI": "10.1067/mai.2003.104",
      "article-title": "Efficacy of liposomal budesonide in experimental asthma",
      "volume": "111",
      "author": "Konduri",
      "year": "2003",
      "journal-title": "J Allergy Clin Immunol"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib67",
      "doi-asserted-by": "crossref",
      "first-page": "964",
      "DOI": "10.1046/j.1365-2133.2002.04800.x",
      "article-title": "Liposomal tacrolimus lotion as a novel topical agent for treatment of immune-mediated skin disorders: experimental studies in a murine model",
      "volume": "146",
      "author": "Erdogan",
      "year": "2002",
      "journal-title": "Br J Dermatol"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib68",
      "doi-asserted-by": "crossref",
      "first-page": "1149",
      "DOI": "10.1081/DDC-120025872",
      "article-title": "Continuous release of interleukin-2 from liposomal IL-2 (mixture of interleukin-2 and liposomes) after subcutaneous administration to mice",
      "volume": "29",
      "author": "Kanaoka",
      "year": "2003",
      "journal-title": "Drug Dev Ind Pharm"
    },
    {
      "key": "10.1016/j.copbio.2004.10.005_bib69",
      "doi-asserted-by": "crossref",
      "first-page": "333",
      "DOI": "10.1093/jac/48.3.333",
      "article-title": "Liposome-encapsulated aminoglycosides in pre-clinical and clinical studies",
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      "author": "Noguchi",
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      "author": "Brignole",
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      "author": "Kita",
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      "author": "Ulanova",
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      "author": "Tanaka",
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      "author": "Wu",
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      "article-title": "Evaluation of genetic immunization adjuvants to improve the effectiveness of a human immunodeficiency virus type 2 (HIV-2) envelope DNA vaccine",
      "volume": "23",
      "author": "Locher",
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      "DOI": "10.1046/j.1365-2222.2002.01514.x",
      "article-title": "Liposome-entrapped D. pteronyssinus vaccination in mild asthma patients: effect of 1-year double-blind, placebo-controlled trial on inflammation, bronchial hyperresponsiveness and immediate and late bronchial responses to the allergen",
      "volume": "32",
      "author": "Alvarez",
      "year": "2002",
      "journal-title": "Clin Exp Allergy"
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      "DOI": "10.1016/j.vaccine.2003.09.030",
      "article-title": "A mixed Th1/Th2 response elicited by a liposomal formulation of Leishmania vaccine instructs Th1 responses and resistance to Leishmania donovani in susceptible BALB/c mice",
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      "volume": "17",
      "author": "Zurbriggen",
      "year": "1999",
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      "first-page": "71",
      "DOI": "10.1016/S0014-5793(01)03112-X",
      "article-title": "Targeting influenza virosomes to ovarian carcinoma cells",
      "volume": "509",
      "author": "Mastrobattista",
      "year": "2001",
      "journal-title": "FEBS Lett"
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      "DOI": "10.1080/02652040010019550",
      "article-title": "Enhanced cytotoxicity of doxorubicin encapsulated in liposomes with reconstituted Sendai F-proteins",
      "volume": "18",
      "author": "Cho",
      "year": "2001",
      "journal-title": "J Microencapsul"
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      "DOI": "10.1089/aid.1992.8.1823",
      "article-title": "Properties of HIV membrane reconstituted from its recombinant gp160 envelope glycoprotein",
      "volume": "8",
      "author": "Cornet",
      "year": "1992",
      "journal-title": "AIDS Res Hum Retroviruses"
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