DOI: 10.1016/j.conb.2006.01.003. RNA binding proteins and the regulation of neuronal synaptic plasticity

RNA binding proteins and the regulation of neuronal synaptic plasticity

10.1016/j.conb.2006.01.003

Crossref journal-article

Elsevier BV

Current Opinion in Neurobiology (78)

Bibliography

Ule, J., & Darnell, R. B. (2006). RNA binding proteins and the regulation of neuronal synaptic plasticity. Current Opinion in Neurobiology, 16(1), 102â110.

Authors 2

Jernej Ule (first)
Robert B Darnell (additional)

References 94 Referenced 143

10.1126/science.1067020 / Science / The molecular biology of memory storage: a dialogue between genes and synapses by Kandel (2001)
10.1038/nature03012 / Nature / Cortical rewiring and information storage by Chklovskii (2004)
10.1016/j.conb.2005.01.002 / Curr Opin Neurobiol / Transcriptional control of cognitive development by Hong (2005)
10.1038/nrn1557 / Nat Rev Neurosci / Biochemical mechanisms for translational regulation in synaptic plasticity by Klann (2004)
10.1186/1471-213X-5-14 / BMC Dev Biol / A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain by McKee (2005)
10.1523/JNEUROSCI.02-03-00284.1982 / J Neurosci / Preferential localization of polyribosomes under the base of dendritic spines in granule cells of the dentate gyrus by Steward (1982)
10.1126/science.273.5280.1402 / Science / A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticity by Kang (1996)
10.1073/pnas.122205699 / Proc Natl Acad Sci USA / Altered synaptic plasticity in a mouse model of fragile X mental retardation by Huber (2002)
10.1016/j.neuron.2005.07.005 / Neuron / Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in Fragile X Syndrome by Koekkoek (2005)
10.1101/lm.72704 / Learn Mem / Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene by Alarcon (2004)
10.1016/S0092-8674(03)01021-3 / Cell / A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia by Si (2003)
10.1016/S0896-6273(00)80630-3 / Neuron / CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapses by Wu (1998)
10.1016/j.cell.2005.07.033 / Cell / Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition by Huang (2005)
10.1016/0006-8993(88)90008-X / Brain Res / Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro by Frey (1988)
10.1038/319774a0 / Nature / Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5 by Morris (1986)
10.1016/S0896-6273(03)00676-7 / Neuron / Activity-dependent mRNA splicing controls ER export and synaptic delivery of NMDA receptors by Mu (2003)
10.1126/science.7569904 / Science / Regulated subcellular distribution of the NR1 subunit of the NMDA receptor by Ehlers (1995)
10.1038/364070a0 / Nature / Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain by Tingley (1993)
10.1038/35073593 / Nature / A CaMK IV responsive RNA element mediates depolarization-induced alternative splicing of ion channels by Xie (2001)
10.1126/science.280.5362.443 / Science / Control of alternative splicing of potassium channels by stress hormones by Xie (1998)
10.1016/j.neuron.2005.07.007 / Neuron / Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2 by Beffert (2005)
10.1126/science.8085156 / Science / Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors by Caceres (1994)
10.1146/annurev.biochem.72.121801.161720 / Annu Rev Biochem / Mechanisms of alternative pre-messenger RNA splicing by Black (2003)
10.1128/MCB.23.6.1874-1884.2003 / Mol Cell Biol / Roles for SR proteins and hnRNP A1 in the regulation of c-src exon N1 by Rooke (2003)
10.1016/j.molcel.2005.07.014 / Mol Cell / Polypyrimidine tract binding protein blocks the 5′ splice site-dependent assembly of U2AF and the prespliceosomal E complex by Sharma (2005)
10.1017/S1355838299981530 / RNA / Coordinate repression of a trio of neuron-specific splicing events by the splicing regulator PTB by Zhang (1999)
10.1128/MCB.23.13.4687-4700.2003 / Mol Cell Biol / Nova regulates GABA(A) receptor gamma2 alternative splicing via a distal downstream UCAU-rich intronic splicing enhancer by Dredge (2003)
10.1017/S1355838202027036 / RNA / Region-specific alternative splicing in the nervous system: implications for regulation by the RNA-binding protein NAPOR by Zhang (2002)
10.1038/ng1610 / Nat Genet / Nova regulates brain-specific splicing to shape the synapse by Ule (2005)
10.1371/journal.pbio.0030158 / PLoS Biol / A combinatorial code for splicing silencing: UAGG and GGGG motifs by Han (2005)
10.1006/excr.1995.1366 / Exp Cell Res / Cell type-specific expression of hnRNP proteins by Kamma (1995)
10.1016/0896-6273(93)90077-5 / Neuron / Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system by Buckanovich (1993)
10.1073/pnas.95.22.13254 / Proc Natl Acad Sci USA / The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia by Yang (1998)
10.1038/sj.emboj.7600630 / EMBO J / Nova autoregulation reveals dual functions in neuronal splicing by Dredge (2005)
10.1016/S0896-6273(00)80900-9 / Neuron / Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability by Jensen (2000)
10.1038/35011540 / Nature / From molecular to modular cell biology by Hartwell (1999)
10.1016/j.sbi.2004.05.004 / Curr Opin Struct Biol / Structure and evolution of transcriptional regulatory networks by Babu (2004)
10.1016/0092-8674(88)90384-4 / Cell / The control of alternative splicing at genes regulating sexual differentiation in D. melanogaster by Nagoshi (1988)
10.1016/0092-8674(91)90090-L / Cell / Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro by Hedley (1991)
10.1016/j.cell.2005.04.027 / Cell / fruitless splicing specifies male courtship behavior in Drosophila by Demir (2005)
10.1038/nature03859 / Nature / Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour by Manoli (2005)
10.1073/pnas.93.16.8175 / Proc Natl Acad Sci USA / Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress by Hentze (1996)
10.1038/ng1080 / Nat Genet / Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery by Hieronymus (2003)
10.1371/journal.pbio.0020079 / PLoS Biol / Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast by Gerber (2004)
10.1093/nar/27.6.1464 / Nucleic Acids Res / Identification of AUF-1 ligands reveals vast diversity of early response gene mRNAs by Bhattacharya (1999)
10.1073/pnas.97.26.14085 / Proc Natl Acad Sci USA / Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays by Tenenbaum (2000)
10.1016/S0092-8674(01)00566-9 / Cell / Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function by Darnell (2001)
10.1016/S0092-8674(01)00568-2 / Cell / Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome by Brown (2001)
10.1126/science.1090095 / Science / CLIP identifies Nova-regulated RNA networks in the brain by Ule (2003)
10.1016/j.cub.2005.03.010 / Curr Biol / Synaptogenesis: a balancing act between excitation and inhibition by Cline (2005)
10.1016/j.conb.2004.01.002 / Curr Opin Neurobiol / Retinal axon guidance: novel mechanisms for steering by van Horck (2004)
10.1016/S0896-6273(02)00978-9 / Neuron / Disruption of dendritic translation of CaMKIIalpha impairs stabilization of synaptic plasticity and memory consolidation by Miller (2002)
10.1073/pnas.93.23.13250 / Proc Natl Acad Sci USA / The 3′-untranslated region of CaMKII alpha is a cis-acting signal for the localization and translation of mRNA in dendrites by Mayford (1996)
10.1016/S0896-6273(00)80591-7 / Neuron / Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites by Steward (1998)
10.1016/S0896-6273(01)00275-6 / Neuron / Selective targeting of newly synthesized Arc mRNA to active synapses requires NMDA receptor activation by Steward (2001)
10.1073/pnas.042693699 / Proc Natl Acad Sci USA / The brain-derived neurotrophic factor enhances synthesis of Arc in synaptoneurosomes by Yin (2002)
10.1523/JNEUROSCI.20-11-03993.2000 / J Neurosci / Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory by Guzowski (2000)
10.1523/JNEUROSCI.23-32-10433.2003 / J Neurosci / Localization of a beta-actin messenger ribonucleoprotein complex with zipcode-binding protein modulates the density of dendritic filopodia and filopodial synapses by Eom (2003)
10.1083/jcb.200105133 / J Cell Biol / A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons by Gu (2002)
10.1016/j.neuron.2004.07.022 / Neuron / Kinesin transports RNA: isolation and characterization of an RNA-transporting granule by Kanai (2004)
10.1038/nature04115 / Nature / Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1 by Huttelmaier (2005)
10.1101/gad.1025202 / Genes Dev / Fragile X-related protein and VIG associate with the RNA interference machinery by Caudy (2002)
10.1101/gad.1022002 / Genes Dev / A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins by Ishizuka (2002)
10.1038/nn1174 / Nat Neurosci / Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway by Jin (2004)
10.1093/emboj/21.9.2139 / EMBO J / N-methyl-D-aspartate receptor signaling results in Aurora kinase-catalyzed CPEB phosphorylation and alpha CaMKII mRNA polyadenylation at synapses by Huang (2002)
10.1016/S0092-8674(04)00115-1 / Cell / Translational control by MAPK signaling in long-term synaptic plasticity and memory by Kelleher (2004)
10.1038/nature03897 / Nature / Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2 by Costa-Mattioli (2005)
10.1093/nar/29.11.2276 / Nucleic Acids Res / The fragile X mental retardation protein inhibits translation via interacting with mRNA by Li (2001)
10.1093/hmg/10.4.329 / Hum Mol Genet / Evidence that fragile X mental retardation protein is a negative regulator of translation by Laggerbauer (2001)
10.1038/ncb1104-1048 / Nat Cell Biol / RNA and microRNAs in fragile X mental retardation by Jin (2004)
10.1111/j.1601-183X.2005.00144.x / Genes Brain Behav / FMRP RNA targets: identification and validation by Darnell (2005)
10.1007/BF00687814 / Acta Neuropathol (Berl) / Adult fragile X syndrome. Clinico-neuropathologic findings by Rudelli (1985)
10.1073/pnas.94.10.5401 / Proc Natl Acad Sci USA / Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits by Comery (1997)
10.1016/j.cub.2004.09.085 / Curr Biol / The Drosophila fragile X gene negatively regulates neuronal elaboration and synaptic differentiation by Pan (2004)
10.1523/JNEUROSCI.21-14-05139.2001 / J Neurosci / Abnormal development of dendritic spines in FMR1 knock-out mice by Nimchinsky (2001)
10.1016/S0092-8674(01)00589-X / Cell / Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function by Zhang (2001)
10.1073/pnas.0404995101 / Proc Natl Acad Sci USA / The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development by Lu (2004)
10.1016/j.cub.2005.05.050 / Curr Biol / The Drosophila fragile X mental retardation protein controls actin dynamics by directly regulating profilin in the brain by Reeve (2005)
10.1101/gad.1276805 / Genes Dev / Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes by Darnell (2005)
10.1016/S1097-2765(00)80012-X / Mol Cell / FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association by Feng (1997)
10.1523/JNEUROSCI.0099-04.2004 / J Neurosci / Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses by Antar (2004)
10.1073/pnas.0407533101 / Proc Natl Acad Sci USA / Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses by Weiler (2004)
10.1016/j.neuron.2005.01.038 / Neuron / Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome by McBride (2005)
10.1523/JNEUROSCI.5051-04.2005 / J Neurosci / Bidirectional regulation of cytoplasmic polyadenylation element-binding protein phosphorylation by Ca2+/calmodulin-dependent protein kinase II and protein phosphatase 1 during hippocampal long-term potentiation by Atkins (2005)
10.1016/S0092-8674(03)01020-1 / Cell / A neuronal isoform of the aplysia CPEB has prion-like properties by Si (2003)
10.1073/pnas.1133424100 / Proc Natl Acad Sci USA / Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus by Theis (2003)
10.1261/rna.2870505 / Rna / Activity-dependent polyadenylation in neurons by Du (2005)
10.1101/gad.1053003 / Genes Dev / Facilitation of dendritic mRNA transport by CPEB by Huang (2003)
10.1016/j.cub.2005.01.058 / Curr Biol / The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology by Fujii (2005)
10.1016/j.devcel.2005.01.011 / Dev Cell / The Drosophila fragile X protein functions as a negative regulator in the orb autoregulatory pathway by Costa (2005)
10.1038/sj.emboj.7600341 / EMBO J / Visualization of RNA-protein interactions in living cells: FMRP and IMP1 interact on mRNAs by Rackham (2004)
10.1016/S0896-6273(02)00606-2 / Neuron / State-dependent heterogeneity in synaptic depression between pyramidal cell pairs by Montgomery (2002)
10.1016/j.tins.2004.10.006 / Trends Neurosci / Discrete synaptic states define a major mechanism of synapse plasticity by Montgomery (2004)
10.1016/j.ymeth.2005.07.018 / Methods / CLIP: a method for identifying protein-RNA interaction sites in living cells by Ule (2005)

Dates

Type	When
Created	19 years, 7 months ago (Jan. 19, 2006, 2:07 p.m.)
Deposited	6 years, 4 months ago (April 15, 2019, 10:06 a.m.)
Indexed	3 months, 1 week ago (May 27, 2025, 1:38 p.m.)
Issued	19 years, 7 months ago (Feb. 1, 2006)
Published	19 years, 7 months ago (Feb. 1, 2006)
Published Print	19 years, 7 months ago (Feb. 1, 2006)

Funders 0

None

BibTeX

@article{Ule_2006, title={RNA binding proteins and the regulation of neuronal synaptic plasticity}, volume={16}, ISSN={0959-4388}, url={http://dx.doi.org/10.1016/j.conb.2006.01.003}, DOI={10.1016/j.conb.2006.01.003}, number={1}, journal={Current Opinion in Neurobiology}, publisher={Elsevier BV}, author={Ule, Jernej and Darnell, Robert B}, year={2006}, month=feb, pages={102–110} }

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      "author": "Frey",
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      "author": "Morris",
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      "volume": "40",
      "author": "Mu",
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      "volume": "269",
      "author": "Ehlers",
      "year": "1995",
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      "year": "1993",
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      "author": "Xie",
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      "journal-title": "Nature"
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      "article-title": "Control of alternative splicing of potassium channels by stress hormones",
      "volume": "280",
      "author": "Xie",
      "year": "1998",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib21_1",
      "doi-asserted-by": "crossref",
      "first-page": "567",
      "DOI": "10.1016/j.neuron.2005.07.007",
      "article-title": "Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2",
      "volume": "47",
      "author": "Beffert",
      "year": "2005",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "1706",
      "DOI": "10.1126/science.8085156",
      "article-title": "Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors",
      "volume": "265",
      "author": "Caceres",
      "year": "1994",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "291",
      "DOI": "10.1146/annurev.biochem.72.121801.161720",
      "article-title": "Mechanisms of alternative pre-messenger RNA splicing",
      "volume": "72",
      "author": "Black",
      "year": "2003",
      "journal-title": "Annu Rev Biochem"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "1874",
      "DOI": "10.1128/MCB.23.6.1874-1884.2003",
      "article-title": "Roles for SR proteins and hnRNP A1 in the regulation of c-src exon N1",
      "volume": "23",
      "author": "Rooke",
      "year": "2003",
      "journal-title": "Mol Cell Biol"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "485",
      "DOI": "10.1016/j.molcel.2005.07.014",
      "article-title": "Polypyrimidine tract binding protein blocks the 5\u2032 splice site-dependent assembly of U2AF and the prespliceosomal E complex",
      "volume": "19",
      "author": "Sharma",
      "year": "2005",
      "journal-title": "Mol Cell"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "117",
      "DOI": "10.1017/S1355838299981530",
      "article-title": "Coordinate repression of a trio of neuron-specific splicing events by the splicing regulator PTB",
      "volume": "5",
      "author": "Zhang",
      "year": "1999",
      "journal-title": "RNA"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "4687",
      "DOI": "10.1128/MCB.23.13.4687-4700.2003",
      "article-title": "Nova regulates GABA(A) receptor gamma2 alternative splicing via a distal downstream UCAU-rich intronic splicing enhancer",
      "volume": "23",
      "author": "Dredge",
      "year": "2003",
      "journal-title": "Mol Cell Biol"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "671",
      "DOI": "10.1017/S1355838202027036",
      "article-title": "Region-specific alternative splicing in the nervous system: implications for regulation by the RNA-binding protein NAPOR",
      "volume": "8",
      "author": "Zhang",
      "year": "2002",
      "journal-title": "RNA"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib29_1",
      "doi-asserted-by": "crossref",
      "first-page": "844",
      "DOI": "10.1038/ng1610",
      "article-title": "Nova regulates brain-specific splicing to shape the synapse",
      "volume": "37",
      "author": "Ule",
      "year": "2005",
      "journal-title": "Nat Genet"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib30_1",
      "doi-asserted-by": "crossref",
      "first-page": "e158",
      "DOI": "10.1371/journal.pbio.0030158",
      "article-title": "A combinatorial code for splicing silencing: UAGG and GGGG motifs",
      "volume": "3",
      "author": "Han",
      "year": "2005",
      "journal-title": "PLoS Biol"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "187",
      "DOI": "10.1006/excr.1995.1366",
      "article-title": "Cell type-specific expression of hnRNP proteins",
      "volume": "221",
      "author": "Kamma",
      "year": "1995",
      "journal-title": "Exp Cell Res"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "657",
      "DOI": "10.1016/0896-6273(93)90077-5",
      "article-title": "Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system",
      "volume": "11",
      "author": "Buckanovich",
      "year": "1993",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "13254",
      "DOI": "10.1073/pnas.95.22.13254",
      "article-title": "The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia",
      "volume": "95",
      "author": "Yang",
      "year": "1998",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "1608",
      "DOI": "10.1038/sj.emboj.7600630",
      "article-title": "Nova autoregulation reveals dual functions in neuronal splicing",
      "volume": "24",
      "author": "Dredge",
      "year": "2005",
      "journal-title": "EMBO J"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "359",
      "DOI": "10.1016/S0896-6273(00)80900-9",
      "article-title": "Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability",
      "volume": "25",
      "author": "Jensen",
      "year": "2000",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "C47",
      "DOI": "10.1038/35011540",
      "article-title": "From molecular to modular cell biology",
      "volume": "402",
      "author": "Hartwell",
      "year": "1999",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib37",
      "doi-asserted-by": "crossref",
      "first-page": "283",
      "DOI": "10.1016/j.sbi.2004.05.004",
      "article-title": "Structure and evolution of transcriptional regulatory networks",
      "volume": "14",
      "author": "Babu",
      "year": "2004",
      "journal-title": "Curr Opin Struct Biol"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib38",
      "doi-asserted-by": "crossref",
      "first-page": "229",
      "DOI": "10.1016/0092-8674(88)90384-4",
      "article-title": "The control of alternative splicing at genes regulating sexual differentiation in D. melanogaster",
      "volume": "53",
      "author": "Nagoshi",
      "year": "1988",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib39",
      "doi-asserted-by": "crossref",
      "first-page": "579",
      "DOI": "10.1016/0092-8674(91)90090-L",
      "article-title": "Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro",
      "volume": "65",
      "author": "Hedley",
      "year": "1991",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib40",
      "doi-asserted-by": "crossref",
      "first-page": "785",
      "DOI": "10.1016/j.cell.2005.04.027",
      "article-title": "fruitless splicing specifies male courtship behavior in Drosophila",
      "volume": "121",
      "author": "Demir",
      "year": "2005",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib41",
      "doi-asserted-by": "crossref",
      "first-page": "395",
      "DOI": "10.1038/nature03859",
      "article-title": "Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour",
      "volume": "436",
      "author": "Manoli",
      "year": "2005",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib42",
      "doi-asserted-by": "crossref",
      "first-page": "8175",
      "DOI": "10.1073/pnas.93.16.8175",
      "article-title": "Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress",
      "volume": "93",
      "author": "Hentze",
      "year": "1996",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib43",
      "doi-asserted-by": "crossref",
      "first-page": "155",
      "DOI": "10.1038/ng1080",
      "article-title": "Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery",
      "volume": "33",
      "author": "Hieronymus",
      "year": "2003",
      "journal-title": "Nat Genet"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib44",
      "doi-asserted-by": "crossref",
      "first-page": "E79",
      "DOI": "10.1371/journal.pbio.0020079",
      "article-title": "Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast",
      "volume": "2",
      "author": "Gerber",
      "year": "2004",
      "journal-title": "PLoS Biol"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib45",
      "doi-asserted-by": "crossref",
      "first-page": "1464",
      "DOI": "10.1093/nar/27.6.1464",
      "article-title": "Identification of AUF-1 ligands reveals vast diversity of early response gene mRNAs",
      "volume": "27",
      "author": "Bhattacharya",
      "year": "1999",
      "journal-title": "Nucleic Acids Res"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib46",
      "doi-asserted-by": "crossref",
      "first-page": "14085",
      "DOI": "10.1073/pnas.97.26.14085",
      "article-title": "Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays",
      "volume": "97",
      "author": "Tenenbaum",
      "year": "2000",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib47",
      "doi-asserted-by": "crossref",
      "first-page": "489",
      "DOI": "10.1016/S0092-8674(01)00566-9",
      "article-title": "Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function",
      "volume": "107",
      "author": "Darnell",
      "year": "2001",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib48",
      "doi-asserted-by": "crossref",
      "first-page": "477",
      "DOI": "10.1016/S0092-8674(01)00568-2",
      "article-title": "Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome",
      "volume": "107",
      "author": "Brown",
      "year": "2001",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib49",
      "doi-asserted-by": "crossref",
      "first-page": "1212",
      "DOI": "10.1126/science.1090095",
      "article-title": "CLIP identifies Nova-regulated RNA networks in the brain",
      "volume": "302",
      "author": "Ule",
      "year": "2003",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib50",
      "doi-asserted-by": "crossref",
      "first-page": "R203",
      "DOI": "10.1016/j.cub.2005.03.010",
      "article-title": "Synaptogenesis: a balancing act between excitation and inhibition",
      "volume": "15",
      "author": "Cline",
      "year": "2005",
      "journal-title": "Curr Biol"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib51",
      "doi-asserted-by": "crossref",
      "first-page": "61",
      "DOI": "10.1016/j.conb.2004.01.002",
      "article-title": "Retinal axon guidance: novel mechanisms for steering",
      "volume": "14",
      "author": "van Horck",
      "year": "2004",
      "journal-title": "Curr Opin Neurobiol"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib52",
      "doi-asserted-by": "crossref",
      "first-page": "507",
      "DOI": "10.1016/S0896-6273(02)00978-9",
      "article-title": "Disruption of dendritic translation of CaMKIIalpha impairs stabilization of synaptic plasticity and memory consolidation",
      "volume": "36",
      "author": "Miller",
      "year": "2002",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib53",
      "doi-asserted-by": "crossref",
      "first-page": "13250",
      "DOI": "10.1073/pnas.93.23.13250",
      "article-title": "The 3\u2032-untranslated region of CaMKII alpha is a cis-acting signal for the localization and translation of mRNA in dendrites",
      "volume": "93",
      "author": "Mayford",
      "year": "1996",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib54",
      "doi-asserted-by": "crossref",
      "first-page": "741",
      "DOI": "10.1016/S0896-6273(00)80591-7",
      "article-title": "Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites",
      "volume": "21",
      "author": "Steward",
      "year": "1998",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib55",
      "doi-asserted-by": "crossref",
      "first-page": "227",
      "DOI": "10.1016/S0896-6273(01)00275-6",
      "article-title": "Selective targeting of newly synthesized Arc mRNA to active synapses requires NMDA receptor activation",
      "volume": "30",
      "author": "Steward",
      "year": "2001",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib56",
      "doi-asserted-by": "crossref",
      "first-page": "2368",
      "DOI": "10.1073/pnas.042693699",
      "article-title": "The brain-derived neurotrophic factor enhances synthesis of Arc in synaptoneurosomes",
      "volume": "99",
      "author": "Yin",
      "year": "2002",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib57",
      "doi-asserted-by": "crossref",
      "first-page": "3993",
      "DOI": "10.1523/JNEUROSCI.20-11-03993.2000",
      "article-title": "Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory",
      "volume": "20",
      "author": "Guzowski",
      "year": "2000",
      "journal-title": "J Neurosci"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib58",
      "doi-asserted-by": "crossref",
      "first-page": "10433",
      "DOI": "10.1523/JNEUROSCI.23-32-10433.2003",
      "article-title": "Localization of a beta-actin messenger ribonucleoprotein complex with zipcode-binding protein modulates the density of dendritic filopodia and filopodial synapses",
      "volume": "23",
      "author": "Eom",
      "year": "2003",
      "journal-title": "J Neurosci"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib59",
      "doi-asserted-by": "crossref",
      "first-page": "41",
      "DOI": "10.1083/jcb.200105133",
      "article-title": "A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons",
      "volume": "156",
      "author": "Gu",
      "year": "2002",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib60_1",
      "doi-asserted-by": "crossref",
      "first-page": "513",
      "DOI": "10.1016/j.neuron.2004.07.022",
      "article-title": "Kinesin transports RNA: isolation and characterization of an RNA-transporting granule",
      "volume": "43",
      "author": "Kanai",
      "year": "2004",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib61_1",
      "doi-asserted-by": "crossref",
      "first-page": "512",
      "DOI": "10.1038/nature04115",
      "article-title": "Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1",
      "volume": "438",
      "author": "Huttelmaier",
      "year": "2005",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib62",
      "doi-asserted-by": "crossref",
      "first-page": "2491",
      "DOI": "10.1101/gad.1025202",
      "article-title": "Fragile X-related protein and VIG associate with the RNA interference machinery",
      "volume": "16",
      "author": "Caudy",
      "year": "2002",
      "journal-title": "Genes Dev"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib63",
      "doi-asserted-by": "crossref",
      "first-page": "2497",
      "DOI": "10.1101/gad.1022002",
      "article-title": "A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins",
      "volume": "16",
      "author": "Ishizuka",
      "year": "2002",
      "journal-title": "Genes Dev"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib64_1",
      "doi-asserted-by": "crossref",
      "first-page": "113",
      "DOI": "10.1038/nn1174",
      "article-title": "Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway",
      "volume": "7",
      "author": "Jin",
      "year": "2004",
      "journal-title": "Nat Neurosci"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib65",
      "doi-asserted-by": "crossref",
      "first-page": "2139",
      "DOI": "10.1093/emboj/21.9.2139",
      "article-title": "N-methyl-D-aspartate receptor signaling results in Aurora kinase-catalyzed CPEB phosphorylation and alpha CaMKII mRNA polyadenylation at synapses",
      "volume": "21",
      "author": "Huang",
      "year": "2002",
      "journal-title": "EMBO J"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib66",
      "doi-asserted-by": "crossref",
      "first-page": "467",
      "DOI": "10.1016/S0092-8674(04)00115-1",
      "article-title": "Translational control by MAPK signaling in long-term synaptic plasticity and memory",
      "volume": "116",
      "author": "Kelleher",
      "year": "2004",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib67",
      "doi-asserted-by": "crossref",
      "first-page": "1166",
      "DOI": "10.1038/nature03897",
      "article-title": "Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2",
      "volume": "436",
      "author": "Costa-Mattioli",
      "year": "2005",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib68",
      "doi-asserted-by": "crossref",
      "first-page": "2276",
      "DOI": "10.1093/nar/29.11.2276",
      "article-title": "The fragile X mental retardation protein inhibits translation via interacting with mRNA",
      "volume": "29",
      "author": "Li",
      "year": "2001",
      "journal-title": "Nucleic Acids Res"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib69",
      "doi-asserted-by": "crossref",
      "first-page": "329",
      "DOI": "10.1093/hmg/10.4.329",
      "article-title": "Evidence that fragile X mental retardation protein is a negative regulator of translation",
      "volume": "10",
      "author": "Laggerbauer",
      "year": "2001",
      "journal-title": "Hum Mol Genet"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib70",
      "doi-asserted-by": "crossref",
      "first-page": "1048",
      "DOI": "10.1038/ncb1104-1048",
      "article-title": "RNA and microRNAs in fragile X mental retardation",
      "volume": "6",
      "author": "Jin",
      "year": "2004",
      "journal-title": "Nat Cell Biol"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib71",
      "doi-asserted-by": "crossref",
      "first-page": "341",
      "DOI": "10.1111/j.1601-183X.2005.00144.x",
      "article-title": "FMRP RNA targets: identification and validation",
      "volume": "4",
      "author": "Darnell",
      "year": "2005",
      "journal-title": "Genes Brain Behav"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib72",
      "doi-asserted-by": "crossref",
      "first-page": "289",
      "DOI": "10.1007/BF00687814",
      "article-title": "Adult fragile X syndrome. Clinico-neuropathologic findings",
      "volume": "67",
      "author": "Rudelli",
      "year": "1985",
      "journal-title": "Acta Neuropathol (Berl)"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib73",
      "doi-asserted-by": "crossref",
      "first-page": "5401",
      "DOI": "10.1073/pnas.94.10.5401",
      "article-title": "Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits",
      "volume": "94",
      "author": "Comery",
      "year": "1997",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/j.conb.2006.01.003_bib74",
      "doi-asserted-by": "crossref",
      "first-page": "1863",
      "DOI": "10.1016/j.cub.2004.09.085",
      "article-title": "The Drosophila fragile X gene negatively regulates neuronal elaboration and synaptic differentiation",
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      "author": "Darnell",
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      "author": "Feng",
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