DOI: 10.1016/j.cocis.2005.11.001. Mucin structure, aggregation, physiological functions and biomedical applications

Mucin structure, aggregation, physiological functions and biomedical applications

10.1016/j.cocis.2005.11.001

Crossref journal-article

Elsevier BV

Current Opinion in Colloid & Interface Science (78)

Bibliography

Bansil, R., & Turner, B. S. (2006). Mucin structure, aggregation, physiological functions and biomedical applications. Current Opinion in Colloid & Interface Science, 11(2â3), 164â170.

Authors 2

Rama Bansil (first)
Bradley S. Turner (additional)

References 60 Referenced 888

{'key': '10.1016/j.cocis.2005.11.001_bib1', 'series-title': 'Physiology of the gastroenterology tract', 'first-page': '617', 'article-title': 'Structure and function of gastrointestinal mucus', 'author': 'Allen', 'year': '1981'} / Physiology of the gastroenterology tract / Structure and function of gastrointestinal mucus by Allen (1981)
{'key': '10.1016/j.cocis.2005.11.001_bib2', 'series-title': 'Physiology of the gastrointestinal tract', 'article-title': 'Gastrointestinal mucus: synthesis, secretion, and function', 'author': 'Neutra', 'year': '1987'} / Physiology of the gastrointestinal tract / Gastrointestinal mucus: synthesis, secretion, and function by Neutra (1987)
10.1016/S0968-0004(01)02052-7 / Trends Biochem Sci / The MUC family: an obituary by Dekker (2002)
10.1042/bj20030096 / Biochem J / N-linked oligosaccharides play a role in disulphide-dependent dimerization of intestinal mucin Muc2 by Bell (2003)
10.1074/jbc.274.45.31751 / J Biol Chem / The structure and assembly of secreted mucins by Perez-Vilar (1999)
10.1016/S0167-4781(99)00099-8 / Biochim Biophys Acta / Cysteine-rich regions of pig gastric mucin contain von Willebrand factor and cystine knot domains at the carboxyl terminal by Turner (1999)
10.1042/0264-6021:3570203 / Biochem J / Role of the cystine-knot motif at the C-terminus of rat mucin protein Muc2 in dimer formation and secretion by Bell (2001)
10.1074/jbc.M313241200 / J Biol Chem / Identification of molecular intermediates in the assembly pathway of the MUC5AC mucin by Sheehan (2004)
10.1006/geno.1996.0637 / Genomics / Human mucin genes assigned to 11p15.5: identification and organization of a cluster of genes by Pigny (1996)
10.1093/oxfordjournals.molbev.a026400 / Mol Biol Evol / Evolution of the large secreted gel-forming mucins by Desseyn (2000)
10.1146/annurev.ph.57.030195.003223 / Annu Rev Physiol / Mucin biophysics by Bansil (1995)
10.1016/S0065-2318(08)60417-5 / Adv Carbohydr Chem Biochem / The macrostructure of mucus glycoproteins in solution by Harding (1989)
{'issue': '22', 'key': '10.1016/j.cocis.2005.11.001_bib13', 'first-page': '5386', 'article-title': 'Biophysical characterization of one-, two-, and three-tandem repeats of human mucin (muc-1) protein core', 'volume': '53', 'author': 'Fontenot', 'year': '1993', 'journal-title': 'Cancer Res'} / Cancer Res / Biophysical characterization of one-, two-, and three-tandem repeats of human mucin (muc-1) protein core by Fontenot (1993)
10.2174/1389557033487809 / Mini Rev Med Chem / Conformation of glycopeptides by Otvos (2003)
10.1016/0144-8617(95)00105-0 / Carbohydr Polym / Transmission electron microscopy studies on pig gastric mucin and its interactions with chitosan by Fiebrig (1995)
10.1016/S0006-3495(02)73934-9 / Biophys J / Heterogeneity and persistence length in human ocular mucins by Round (2002)
10.1088/0957-4484/15/11/001 / Nanotechnology / Reducing a polymer to its subunits as an aid to molecular mapping by Brayshaw (2004)
10.1042/0264-6021:3480557 / Biochem J / Atomic force microscopy of gastric mucin and chitosan mucoadhesive systems by Deacon (2000)
10.1016/S0006-3495(99)76910-9 / Biophys J / Atomic force microscopy of the submolecular architecture of hydrated ocular mucins by McMaster (1999)
10.1016/j.jsb.2003.10.029 / J Struct Biol / Glycopolymer charge density determines conformation in human ocular mucin gene products: an atomic force microscope study by Round (2004)
10.1021/bm0505843 / Biomacromolecules / Atomic force microscopy reveals aggregation of gastric mucin at low pH by Hong (2005)
10.1016/S0006-3495(99)77288-7 / Biophys J / pH-dependent conformational change of gastric mucin leads to sol–gel transition by Cao (1999)
10.1021/bm025767t / Biomacromolecules / The gel matrix of gastric mucus is maintained by a complex interplay of transient and nontransient associations by Taylor (2003)
10.1021/la050779w / Langmuir / Porcine Gastric Mucin (PGM) at the Water/Poly(dimethylsiloxane) (PDMS) Interface: influence of pH and ionic strength on its conformation, adsorption, and aqueous lubrication properties by Lee (2005)
10.1021/bm005532m / Biomacromolecules / Self-association of mucin by Bromberg (2000)
10.1016/0141-8130(95)01086-6 / Int J Biol Macromol / Gelation of fractionated canine submaxillary mucin in a chaotropic solvent by McCullagh (1996)
{'issue': '5 Pt 1', 'key': '10.1016/j.cocis.2005.11.001_bib27', 'first-page': 'G827', 'article-title': 'Profound increase in viscosity and aggregation of pig gastric mucin at low pH', 'volume': '261', 'author': 'Bhaskar', 'year': '1991', 'journal-title': 'Am J Physiol'} / Am J Physiol / Profound increase in viscosity and aggregation of pig gastric mucin at low pH by Bhaskar (1991)
10.1016/S0142-9612(96)00180-9 / Biomaterials / Comparative rheological investigation of crude gastric mucin and natural gastric mucus by Kočevar-Nared (1997)
Cao X. Aggregation and gelation of mucin and its interactions with lipid vesicles. Ph. D Dissertation, Boston University, Boston MA, 1997.
10.1021/ma00056a044 / Macromolecules / Liquid-crystalline order in mucus by Viney (1993)
10.1016/S0040-6031(98)00275-5 / Thermochim Acta / Water-mucin phases: conditions for mucus liquid crystallinity by Davies (1998)
10.1021/la025515d / Langmuir / Entanglement coupling in porcine stomach mucin by Waigh (2002)
10.1080/02648725.1999.10647971 / Biotechnol Genet Eng Rev / Biopolymer mucoadhesives by Harding (1999)
10.1021/bm000145y / Biomacromolecules / Exploring the molecular adhesion of ocular mucins by Berry (2001)
10.1006/jcis.2000.6724 / J Colloid Interface Sci / Mucin adsorption to hydrophobic surfaces by Shi (2000)
10.1016/S0006-355X(98)00006-7 / Biorheology / Effects of lipids on the structure and rheology of gels formed by canine submaxillary mucin by Rogunova (1997)
10.1080/07391102.2003.10506874 / J Biomol Struct Dyn / Structural modification and aggregation of mucin by chromium (III) complexes by Shrivastava (2003)
10.1016/S0006-3495(97)78224-9 / Biophys J / Diffusion behavior of lipid vesicles in entangled polymer solutions by Cao (1997)
10.1021/bm0341733 / Biomacromolecules / Interaction of mucin with cholesterol enriched vesicles: role of mucin structural domains by Afdhal (2004)
10.1016/S0006-3495(01)75844-4 / Biophys J / Diffusion of macromolecules and virus-like particles in human cervical mucus by Olmsted (2001)
10.1021/bm0493990 / Biomacromolecules / Viscoelastic properties and dynamics of porcine gastric mucin by Celli (2005)
10.1038/360458a0 / Nature / Viscous fingering of HCl through gastric mucin by Bhaskar (1992)
10.1016/S0305-0491(00)00190-5 / Comp Biochem Physiol B / Effects of rabbit gastrointestinal mucins and dextran on hydrochloride diffusion in vitro by Fujita (2000)
10.1053/gast.2000.19455 / Gastroenterology / Acid transport through channels in the mucous layer of rat stomach by Johansson (2000)
10.1042/bst0230836 / Biochem Soc Trans / Interactions between human respiratory mucins and pathogens by Scharfman (1995)
{'issue': '2', 'key': '10.1016/j.cocis.2005.11.001_bib46', 'first-page': '147', 'article-title': 'Role of mucus in gastric mucosal protection', 'volume': '42', 'author': 'Slomiany', 'year': '1991', 'journal-title': 'J Physiol Pharmacol'} / J Physiol Pharmacol / Role of mucus in gastric mucosal protection by Slomiany (1991)
10.2741/Jain / Front Biosci / Mucins in protozoan parasites by Jain (2001)
10.1183/09031936.03.00057003 / Eur Respir J / New concepts of the pathogenesis of cystic fibrosis lung disease by Boucher (2004)
{'issue': '4 Pt 1', 'key': '10.1016/j.cocis.2005.11.001_bib49', 'first-page': 'L413', 'article-title': 'Mucins: structure, function and role in pulmonary diseases', 'volume': '263', 'author': 'Rose', 'year': '1992', 'journal-title': 'Am J Physiol'} / Am J Physiol / Mucins: structure, function and role in pulmonary diseases by Rose (1992)
Smith B, LaMont J. The Pathogenesis of Gallstones. Hospital Practice; 1984. 19(12): 93–99, 103–104. (10.1080/21548331.1984.11702958)
10.1006/exer.2001.1045 / Exp Eye Res / Epithelial mucins of the ocular surface: structure, biosynthesis and function by Argüeso (2001)
10.1038/nrc1251 / Nat Rev Cancer / Mucins in cancer: protection and control of the cell surface by Hollingsworth (2004)
10.1016/S0939-6411(03)00061-4 / Eur J Pharm Biopharm / Thiolated polymers: evidence for the formation of disulphide bonds with mucus glycoproteins by Leitner (2003)
10.1053/j.gastro.2003.11.059 / Gastroenterology / Regulated alkali secretion acts in tandem with unstirred layers to regulate mouse gastric surface pH by Baumgartner (2004)
10.1016/S0169-409X(01)00115-6 / Adv Drug Deliv Rev / Drug transfer through mucus by Khanvilkar (2001)
10.1021/bp0342553 / Biotechnol Prog / Transport of polymeric nanoparticle gene carriers in gastric mucus by Dawson (2004)
{'year': '1996', 'series-title': 'Oral mucosal drug delivery', 'key': '10.1016/j.cocis.2005.11.001_bib57_1'} / Oral mucosal drug delivery (1996)
10.1080/10409239891204198 / Crit Rev Biochem Mol Biol / Concepts and priciples of O-linked glycosylation by Van den Steen (1998)
10.1164/ajrccm.160.supplement_1.12 / Am J Respir Crit Care Med / Control of mucin transcription by diverse injury-induced signaling pathways by Basbaum (1999)
10.1146/annurev.ph.52.030190.001105 / Annu Rev Physiol / Goblet cells secretion and mucogenesis by Verdugo (1990)

Dates

Type	When
Created	19 years, 7 months ago (Jan. 19, 2006, 9:07 a.m.)
Deposited	6 years, 4 months ago (April 15, 2019, 7:11 a.m.)
Indexed	1 day ago (Aug. 23, 2025, 9:41 p.m.)
Issued	19 years, 2 months ago (June 1, 2006)
Published	19 years, 2 months ago (June 1, 2006)
Published Print	19 years, 2 months ago (June 1, 2006)

Funders 0

None

BibTeX

@article{Bansil_2006, title={Mucin structure, aggregation, physiological functions and biomedical applications}, volume={11}, ISSN={1359-0294}, url={http://dx.doi.org/10.1016/j.cocis.2005.11.001}, DOI={10.1016/j.cocis.2005.11.001}, number={2–3}, journal={Current Opinion in Colloid & Interface Science}, publisher={Elsevier BV}, author={Bansil, Rama and Turner, Bradley S.}, year={2006}, month=jun, pages={164–170} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        24
      ]
    ],
    "date-time": "2025-08-24T01:41:47Z",
    "timestamp": 1755999707759
  },
  "reference-count": 60,
  "publisher": "Elsevier BV",
  "issue": "2-3",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2006,
            6,
            1
          ]
        ],
        "date-time": "2006-06-01T00:00:00Z",
        "timestamp": 1149120000000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2006,
        6
      ]
    ]
  },
  "DOI": "10.1016/j.cocis.2005.11.001",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2006,
        1,
        19
      ]
    ],
    "date-time": "2006-01-19T14:07:22Z",
    "timestamp": 1137679642000
  },
  "page": "164-170",
  "source": "Crossref",
  "is-referenced-by-count": 888,
  "title": "Mucin structure, aggregation, physiological functions and biomedical applications",
  "prefix": "10.1016",
  "volume": "11",
  "author": [
    {
      "given": "Rama",
      "family": "Bansil",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Bradley S.",
      "family": "Turner",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/j.cocis.2005.11.001_bib1",
      "series-title": "Physiology of the gastroenterology tract",
      "first-page": "617",
      "article-title": "Structure and function of gastrointestinal mucus",
      "author": "Allen",
      "year": "1981"
    },
    {
      "key": "10.1016/j.cocis.2005.11.001_bib2",
      "series-title": "Physiology of the gastrointestinal tract",
      "article-title": "Gastrointestinal mucus: synthesis, secretion, and function",
      "author": "Neutra",
      "year": "1987"
    },
    {
      "issue": "3",
      "key": "10.1016/j.cocis.2005.11.001_bib3_1",
      "doi-asserted-by": "crossref",
      "first-page": "126",
      "DOI": "10.1016/S0968-0004(01)02052-7",
      "article-title": "The MUC family: an obituary",
      "volume": "27",
      "author": "Dekker",
      "year": "2002",
      "journal-title": "Trends Biochem Sci"
    },
    {
      "issue": "Pt 3",
      "key": "10.1016/j.cocis.2005.11.001_bib4",
      "doi-asserted-by": "crossref",
      "first-page": "893",
      "DOI": "10.1042/bj20030096",
      "article-title": "N-linked oligosaccharides play a role in disulphide-dependent dimerization of intestinal mucin Muc2",
      "volume": "373",
      "author": "Bell",
      "year": "2003",
      "journal-title": "Biochem J"
    },
    {
      "issue": "45",
      "key": "10.1016/j.cocis.2005.11.001_bib5_1",
      "doi-asserted-by": "crossref",
      "first-page": "31751",
      "DOI": "10.1074/jbc.274.45.31751",
      "article-title": "The structure and assembly of secreted mucins",
      "volume": "274",
      "author": "Perez-Vilar",
      "year": "1999",
      "journal-title": "J Biol Chem"
    },
    {
      "issue": "1",
      "key": "10.1016/j.cocis.2005.11.001_bib6",
      "doi-asserted-by": "crossref",
      "first-page": "77",
      "DOI": "10.1016/S0167-4781(99)00099-8",
      "article-title": "Cysteine-rich regions of pig gastric mucin contain von Willebrand factor and cystine knot domains at the carboxyl terminal",
      "volume": "1447",
      "author": "Turner",
      "year": "1999",
      "journal-title": "Biochim Biophys Acta"
    },
    {
      "issue": "Pt1",
      "key": "10.1016/j.cocis.2005.11.001_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "203",
      "DOI": "10.1042/0264-6021:3570203",
      "article-title": "Role of the cystine-knot motif at the C-terminus of rat mucin protein Muc2 in dimer formation and secretion",
      "volume": "357",
      "author": "Bell",
      "year": "2001",
      "journal-title": "Biochem J"
    },
    {
      "issue": "15",
      "key": "10.1016/j.cocis.2005.11.001_bib8",
      "doi-asserted-by": "crossref",
      "first-page": "15698",
      "DOI": "10.1074/jbc.M313241200",
      "article-title": "Identification of molecular intermediates in the assembly pathway of the MUC5AC mucin",
      "volume": "279",
      "author": "Sheehan",
      "year": "2004",
      "journal-title": "J Biol Chem"
    },
    {
      "issue": "3",
      "key": "10.1016/j.cocis.2005.11.001_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "340",
      "DOI": "10.1006/geno.1996.0637",
      "article-title": "Human mucin genes assigned to 11p15.5: identification and organization of a cluster of genes",
      "volume": "38",
      "author": "Pigny",
      "year": "1996",
      "journal-title": "Genomics"
    },
    {
      "issue": "8",
      "key": "10.1016/j.cocis.2005.11.001_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "1175",
      "DOI": "10.1093/oxfordjournals.molbev.a026400",
      "article-title": "Evolution of the large secreted gel-forming mucins",
      "volume": "17",
      "author": "Desseyn",
      "year": "2000",
      "journal-title": "Mol Biol Evol"
    },
    {
      "key": "10.1016/j.cocis.2005.11.001_bib11_1",
      "doi-asserted-by": "crossref",
      "first-page": "635",
      "DOI": "10.1146/annurev.ph.57.030195.003223",
      "article-title": "Mucin biophysics",
      "volume": "57",
      "author": "Bansil",
      "year": "1995",
      "journal-title": "Annu Rev Physiol"
    },
    {
      "key": "10.1016/j.cocis.2005.11.001_bib12_1",
      "doi-asserted-by": "crossref",
      "first-page": "345",
      "DOI": "10.1016/S0065-2318(08)60417-5",
      "article-title": "The macrostructure of mucus glycoproteins in solution",
      "volume": "47",
      "author": "Harding",
      "year": "1989",
      "journal-title": "Adv Carbohydr Chem Biochem"
    },
    {
      "issue": "22",
      "key": "10.1016/j.cocis.2005.11.001_bib13",
      "first-page": "5386",
      "article-title": "Biophysical characterization of one-, two-, and three-tandem repeats of human mucin (muc-1) protein core",
      "volume": "53",
      "author": "Fontenot",
      "year": "1993",
      "journal-title": "Cancer Res"
    },
    {
      "issue": "7",
      "key": "10.1016/j.cocis.2005.11.001_bib14_1",
      "doi-asserted-by": "crossref",
      "first-page": "703",
      "DOI": "10.2174/1389557033487809",
      "article-title": "Conformation of glycopeptides",
      "volume": "3",
      "author": "Otvos",
      "year": "2003",
      "journal-title": "Mini Rev Med Chem"
    },
    {
      "issue": "3",
      "key": "10.1016/j.cocis.2005.11.001_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "239",
      "DOI": "10.1016/0144-8617(95)00105-0",
      "article-title": "Transmission electron microscopy studies on pig gastric mucin and its interactions with chitosan",
      "volume": "28",
      "author": "Fiebrig",
      "year": "1995",
      "journal-title": "Carbohydr Polym"
    },
    {
      "issue": "3",
      "key": "10.1016/j.cocis.2005.11.001_bib16_1",
      "doi-asserted-by": "crossref",
      "first-page": "1661",
      "DOI": "10.1016/S0006-3495(02)73934-9",
      "article-title": "Heterogeneity and persistence length in human ocular mucins",
      "volume": "83",
      "author": "Round",
      "year": "2002",
      "journal-title": "Biophys J"
    },
    {
      "issue": "11",
      "key": "10.1016/j.cocis.2005.11.001_bib17",
      "doi-asserted-by": "crossref",
      "first-page": "1391",
      "DOI": "10.1088/0957-4484/15/11/001",
      "article-title": "Reducing a polymer to its subunits as an aid to molecular mapping",
      "volume": "15",
      "author": "Brayshaw",
      "year": "2004",
      "journal-title": "Nanotechnology"
    },
    {
      "issue": "Pt 3",
      "key": "10.1016/j.cocis.2005.11.001_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "557",
      "DOI": "10.1042/0264-6021:3480557",
      "article-title": "Atomic force microscopy of gastric mucin and chitosan mucoadhesive systems",
      "volume": "348",
      "author": "Deacon",
      "year": "2000",
      "journal-title": "Biochem J"
    },
    {
      "issue": "1",
      "key": "10.1016/j.cocis.2005.11.001_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "533",
      "DOI": "10.1016/S0006-3495(99)76910-9",
      "article-title": "Atomic force microscopy of the submolecular architecture of hydrated ocular mucins",
      "volume": "77",
      "author": "McMaster",
      "year": "1999",
      "journal-title": "Biophys J"
    },
    {
      "issue": "3",
      "key": "10.1016/j.cocis.2005.11.001_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "246",
      "DOI": "10.1016/j.jsb.2003.10.029",
      "article-title": "Glycopolymer charge density determines conformation in human ocular mucin gene products: an atomic force microscope study",
      "volume": "145",
      "author": "Round",
      "year": "2004",
      "journal-title": "J Struct Biol"
    },
    {
      "issue": "6",
      "key": "10.1016/j.cocis.2005.11.001_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "3458",
      "DOI": "10.1021/bm0505843",
      "article-title": "Atomic force microscopy reveals aggregation of gastric mucin at low pH",
      "volume": "6",
      "author": "Hong",
      "year": "2005",
      "journal-title": "Biomacromolecules"
    },
    {
      "issue": "3",
      "key": "10.1016/j.cocis.2005.11.001_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "1250",
      "DOI": "10.1016/S0006-3495(99)77288-7",
      "article-title": "pH-dependent conformational change of gastric mucin leads to sol\u2013gel transition",
      "volume": "76",
      "author": "Cao",
      "year": "1999",
      "journal-title": "Biophys J"
    },
    {
      "issue": "4",
      "key": "10.1016/j.cocis.2005.11.001_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "922",
      "DOI": "10.1021/bm025767t",
      "article-title": "The gel matrix of gastric mucus is maintained by a complex interplay of transient and nontransient associations",
      "volume": "4",
      "author": "Taylor",
      "year": "2003",
      "journal-title": "Biomacromolecules"
    },
    {
      "issue": "18",
      "key": "10.1016/j.cocis.2005.11.001_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "8344",
      "DOI": "10.1021/la050779w",
      "article-title": "Porcine Gastric Mucin (PGM) at the Water/Poly(dimethylsiloxane) (PDMS) Interface: influence of pH and ionic strength on its conformation, adsorption, and aqueous lubrication properties",
      "volume": "21",
      "author": "Lee",
      "year": "2005",
      "journal-title": "Langmuir"
    },
    {
      "issue": "3",
      "key": "10.1016/j.cocis.2005.11.001_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "325",
      "DOI": "10.1021/bm005532m",
      "article-title": "Self-association of mucin",
      "volume": "1",
      "author": "Bromberg",
      "year": "2000",
      "journal-title": "Biomacromolecules"
    },
    {
      "issue": "4",
      "key": "10.1016/j.cocis.2005.11.001_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "247",
      "DOI": "10.1016/0141-8130(95)01086-6",
      "article-title": "Gelation of fractionated canine submaxillary mucin in a chaotropic solvent",
      "volume": "18",
      "author": "McCullagh",
      "year": "1996",
      "journal-title": "Int J Biol Macromol"
    },
    {
      "issue": "5 Pt 1",
      "key": "10.1016/j.cocis.2005.11.001_bib27",
      "first-page": "G827",
      "article-title": "Profound increase in viscosity and aggregation of pig gastric mucin at low pH",
      "volume": "261",
      "author": "Bhaskar",
      "year": "1991",
      "journal-title": "Am J Physiol"
    },
    {
      "issue": "9",
      "key": "10.1016/j.cocis.2005.11.001_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "677",
      "DOI": "10.1016/S0142-9612(96)00180-9",
      "article-title": "Comparative rheological investigation of crude gastric mucin and natural gastric mucus",
      "volume": "18",
      "author": "Ko\u010devar-Nared",
      "year": "1997",
      "journal-title": "Biomaterials"
    },
    {
      "key": "10.1016/j.cocis.2005.11.001_bib29",
      "unstructured": "Cao X. Aggregation and gelation of mucin and its interactions with lipid vesicles. Ph. D Dissertation, Boston University, Boston MA, 1997."
    },
    {
      "issue": "4",
      "key": "10.1016/j.cocis.2005.11.001_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "852",
      "DOI": "10.1021/ma00056a044",
      "article-title": "Liquid-crystalline order in mucus",
      "volume": "26",
      "author": "Viney",
      "year": "1993",
      "journal-title": "Macromolecules"
    },
    {
      "issue": "1",
      "key": "10.1016/j.cocis.2005.11.001_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "39",
      "DOI": "10.1016/S0040-6031(98)00275-5",
      "article-title": "Water-mucin phases: conditions for mucus liquid crystallinity",
      "volume": "315",
      "author": "Davies",
      "year": "1998",
      "journal-title": "Thermochim Acta"
    },
    {
      "issue": "19",
      "key": "10.1016/j.cocis.2005.11.001_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "7188",
      "DOI": "10.1021/la025515d",
      "article-title": "Entanglement coupling in porcine stomach mucin",
      "volume": "18",
      "author": "Waigh",
      "year": "2002",
      "journal-title": "Langmuir"
    },
    {
      "key": "10.1016/j.cocis.2005.11.001_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "41",
      "DOI": "10.1080/02648725.1999.10647971",
      "article-title": "Biopolymer mucoadhesives",
      "volume": "16",
      "author": "Harding",
      "year": "1999",
      "journal-title": "Biotechnol Genet Eng Rev"
    },
    {
      "issue": "2",
      "key": "10.1016/j.cocis.2005.11.001_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "498",
      "DOI": "10.1021/bm000145y",
      "article-title": "Exploring the molecular adhesion of ocular mucins",
      "volume": "2",
      "author": "Berry",
      "year": "2001",
      "journal-title": "Biomacromolecules"
    },
    {
      "issue": "2",
      "key": "10.1016/j.cocis.2005.11.001_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "372",
      "DOI": "10.1006/jcis.2000.6724",
      "article-title": "Mucin adsorption to hydrophobic surfaces",
      "volume": "224",
      "author": "Shi",
      "year": "2000",
      "journal-title": "J Colloid Interface Sci"
    },
    {
      "issue": "4\u20135",
      "key": "10.1016/j.cocis.2005.11.001_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "295",
      "DOI": "10.1016/S0006-355X(98)00006-7",
      "article-title": "Effects of lipids on the structure and rheology of gels formed by canine submaxillary mucin",
      "volume": "34",
      "author": "Rogunova",
      "year": "1997",
      "journal-title": "Biorheology"
    },
    {
      "issue": "4",
      "key": "10.1016/j.cocis.2005.11.001_bib37",
      "doi-asserted-by": "crossref",
      "first-page": "575",
      "DOI": "10.1080/07391102.2003.10506874",
      "article-title": "Structural modification and aggregation of mucin by chromium (III) complexes",
      "volume": "20",
      "author": "Shrivastava",
      "year": "2003",
      "journal-title": "J Biomol Struct Dyn"
    },
    {
      "issue": "4",
      "key": "10.1016/j.cocis.2005.11.001_bib38",
      "doi-asserted-by": "crossref",
      "first-page": "1932",
      "DOI": "10.1016/S0006-3495(97)78224-9",
      "article-title": "Diffusion behavior of lipid vesicles in entangled polymer solutions",
      "volume": "73",
      "author": "Cao",
      "year": "1997",
      "journal-title": "Biophys J"
    },
    {
      "issue": "2",
      "key": "10.1016/j.cocis.2005.11.001_bib39",
      "doi-asserted-by": "crossref",
      "first-page": "269",
      "DOI": "10.1021/bm0341733",
      "article-title": "Interaction of mucin with cholesterol enriched vesicles: role of mucin structural domains",
      "volume": "5",
      "author": "Afdhal",
      "year": "2004",
      "journal-title": "Biomacromolecules"
    },
    {
      "issue": "4",
      "key": "10.1016/j.cocis.2005.11.001_bib40",
      "doi-asserted-by": "crossref",
      "first-page": "1930",
      "DOI": "10.1016/S0006-3495(01)75844-4",
      "article-title": "Diffusion of macromolecules and virus-like particles in human cervical mucus",
      "volume": "81",
      "author": "Olmsted",
      "year": "2001",
      "journal-title": "Biophys J"
    },
    {
      "issue": "3",
      "key": "10.1016/j.cocis.2005.11.001_bib41",
      "doi-asserted-by": "crossref",
      "first-page": "1329",
      "DOI": "10.1021/bm0493990",
      "article-title": "Viscoelastic properties and dynamics of porcine gastric mucin",
      "volume": "6",
      "author": "Celli",
      "year": "2005",
      "journal-title": "Biomacromolecules"
    },
    {
      "issue": "6403",
      "key": "10.1016/j.cocis.2005.11.001_bib42",
      "doi-asserted-by": "crossref",
      "first-page": "458",
      "DOI": "10.1038/360458a0",
      "article-title": "Viscous fingering of HCl through gastric mucin",
      "volume": "360",
      "author": "Bhaskar",
      "year": "1992",
      "journal-title": "Nature"
    },
    {
      "issue": "3",
      "key": "10.1016/j.cocis.2005.11.001_bib43",
      "doi-asserted-by": "crossref",
      "first-page": "353",
      "DOI": "10.1016/S0305-0491(00)00190-5",
      "article-title": "Effects of rabbit gastrointestinal mucins and dextran on hydrochloride diffusion in vitro",
      "volume": "126",
      "author": "Fujita",
      "year": "2000",
      "journal-title": "Comp Biochem Physiol B"
    },
    {
      "key": "10.1016/j.cocis.2005.11.001_bib44",
      "doi-asserted-by": "crossref",
      "first-page": "1297",
      "DOI": "10.1053/gast.2000.19455",
      "article-title": "Acid transport through channels in the mucous layer of rat stomach",
      "volume": "119",
      "author": "Johansson",
      "year": "2000",
      "journal-title": "Gastroenterology"
    },
    {
      "issue": "4",
      "key": "10.1016/j.cocis.2005.11.001_bib45",
      "doi-asserted-by": "crossref",
      "first-page": "836",
      "DOI": "10.1042/bst0230836",
      "article-title": "Interactions between human respiratory mucins and pathogens",
      "volume": "23",
      "author": "Scharfman",
      "year": "1995",
      "journal-title": "Biochem Soc Trans"
    },
    {
      "issue": "2",
      "key": "10.1016/j.cocis.2005.11.001_bib46",
      "first-page": "147",
      "article-title": "Role of mucus in gastric mucosal protection",
      "volume": "42",
      "author": "Slomiany",
      "year": "1991",
      "journal-title": "J Physiol Pharmacol"
    },
    {
      "key": "10.1016/j.cocis.2005.11.001_bib47",
      "doi-asserted-by": "crossref",
      "first-page": "D1276",
      "DOI": "10.2741/Jain",
      "article-title": "Mucins in protozoan parasites",
      "volume": "6",
      "author": "Jain",
      "year": "2001",
      "journal-title": "Front Biosci"
    },
    {
      "issue": "1",
      "key": "10.1016/j.cocis.2005.11.001_bib48_1",
      "doi-asserted-by": "crossref",
      "first-page": "146",
      "DOI": "10.1183/09031936.03.00057003",
      "article-title": "New concepts of the pathogenesis of cystic fibrosis lung disease",
      "volume": "23",
      "author": "Boucher",
      "year": "2004",
      "journal-title": "Eur Respir J"
    },
    {
      "issue": "4 Pt 1",
      "key": "10.1016/j.cocis.2005.11.001_bib49",
      "first-page": "L413",
      "article-title": "Mucins: structure, function and role in pulmonary diseases",
      "volume": "263",
      "author": "Rose",
      "year": "1992",
      "journal-title": "Am J Physiol"
    },
    {
      "key": "10.1016/j.cocis.2005.11.001_bib50",
      "doi-asserted-by": "crossref",
      "unstructured": "Smith B, LaMont J. The Pathogenesis of Gallstones. Hospital Practice; 1984. 19(12): 93\u201399, 103\u2013104.",
      "DOI": "10.1080/21548331.1984.11702958"
    },
    {
      "issue": "3",
      "key": "10.1016/j.cocis.2005.11.001_bib51_1",
      "doi-asserted-by": "crossref",
      "first-page": "281",
      "DOI": "10.1006/exer.2001.1045",
      "article-title": "Epithelial mucins of the ocular surface: structure, biosynthesis and function",
      "volume": "73",
      "author": "Arg\u00fceso",
      "year": "2001",
      "journal-title": "Exp Eye Res"
    },
    {
      "issue": "1",
      "key": "10.1016/j.cocis.2005.11.001_bib52_1",
      "doi-asserted-by": "crossref",
      "first-page": "45",
      "DOI": "10.1038/nrc1251",
      "article-title": "Mucins in cancer: protection and control of the cell surface",
      "volume": "4",
      "author": "Hollingsworth",
      "year": "2004",
      "journal-title": "Nat Rev Cancer"
    },
    {
      "issue": "2",
      "key": "10.1016/j.cocis.2005.11.001_bib53",
      "doi-asserted-by": "crossref",
      "first-page": "207",
      "DOI": "10.1016/S0939-6411(03)00061-4",
      "article-title": "Thiolated polymers: evidence for the formation of disulphide bonds with mucus glycoproteins",
      "volume": "56",
      "author": "Leitner",
      "year": "2003",
      "journal-title": "Eur J Pharm Biopharm"
    },
    {
      "issue": "3",
      "key": "10.1016/j.cocis.2005.11.001_bib54",
      "doi-asserted-by": "crossref",
      "first-page": "774",
      "DOI": "10.1053/j.gastro.2003.11.059",
      "article-title": "Regulated alkali secretion acts in tandem with unstirred layers to regulate mouse gastric surface pH",
      "volume": "126",
      "author": "Baumgartner",
      "year": "2004",
      "journal-title": "Gastroenterology"
    },
    {
      "key": "10.1016/j.cocis.2005.11.001_bib55",
      "doi-asserted-by": "crossref",
      "first-page": "173",
      "DOI": "10.1016/S0169-409X(01)00115-6",
      "article-title": "Drug transfer through mucus",
      "volume": "48",
      "author": "Khanvilkar",
      "year": "2001",
      "journal-title": "Adv Drug Deliv Rev"
    },
    {
      "issue": "3",
      "key": "10.1016/j.cocis.2005.11.001_bib56",
      "doi-asserted-by": "crossref",
      "first-page": "851",
      "DOI": "10.1021/bp0342553",
      "article-title": "Transport of polymeric nanoparticle gene carriers in gastric mucus",
      "volume": "20",
      "author": "Dawson",
      "year": "2004",
      "journal-title": "Biotechnol Prog"
    },
    {
      "year": "1996",
      "series-title": "Oral mucosal drug delivery",
      "key": "10.1016/j.cocis.2005.11.001_bib57_1"
    },
    {
      "issue": "3",
      "key": "10.1016/j.cocis.2005.11.001_bib58",
      "doi-asserted-by": "crossref",
      "first-page": "151",
      "DOI": "10.1080/10409239891204198",
      "article-title": "Concepts and priciples of O-linked glycosylation",
      "volume": "33",
      "author": "Van den Steen",
      "year": "1998",
      "journal-title": "Crit Rev Biochem Mol Biol"
    },
    {
      "key": "10.1016/j.cocis.2005.11.001_bib59",
      "doi-asserted-by": "crossref",
      "first-page": "544",
      "DOI": "10.1164/ajrccm.160.supplement_1.12",
      "article-title": "Control of mucin transcription by diverse injury-induced signaling pathways",
      "volume": "160",
      "author": "Basbaum",
      "year": "1999",
      "journal-title": "Am J Respir Crit Care Med"
    },
    {
      "key": "10.1016/j.cocis.2005.11.001_bib60",
      "doi-asserted-by": "crossref",
      "first-page": "157",
      "DOI": "10.1146/annurev.ph.52.030190.001105",
      "article-title": "Goblet cells secretion and mucogenesis",
      "volume": "52",
      "author": "Verdugo",
      "year": "1990",
      "journal-title": "Annu Rev Physiol"
    }
  ],
  "container-title": "Current Opinion in Colloid &amp; Interface Science",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S1359029405001184?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S1359029405001184?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2019,
        4,
        15
      ]
    ],
    "date-time": "2019-04-15T11:11:23Z",
    "timestamp": 1555326683000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S1359029405001184"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2006,
        6
      ]
    ]
  },
  "references-count": 60,
  "journal-issue": {
    "issue": "2-3",
    "published-print": {
      "date-parts": [
        [
          2006,
          6
        ]
      ]
    }
  },
  "alternative-id": [
    "S1359029405001184"
  ],
  "URL": "http://dx.doi.org/10.1016/j.cocis.2005.11.001",
  "relation": {},
  "ISSN": [
    "1359-0294"
  ],
  "subject": [],
  "container-title-short": "Current Opinion in Colloid &amp; Interface Science",
  "published": {
    "date-parts": [
      [
        2006,
        6
      ]
    ]
  }
}