DOI: 10.1016/j.cell.2009.07.045. Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability

Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability

10.1016/j.cell.2009.07.045

Crossref journal-article

Elsevier BV

Cell (78)

Bibliography

VÃ¶gtle, F.-N., Wortelkamp, S., Zahedi, R. P., Becker, D., Leidhold, C., Gevaert, K., Kellermann, J., Voos, W., Sickmann, A., Pfanner, N., & Meisinger, C. (2009). Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability. Cell, 139(2), 428â439.

Authors 11

F.-Nora Vögtle (first)
Stefanie Wortelkamp (additional)
René P. Zahedi (additional)
Dorothea Becker (additional)
Claudia Leidhold (additional)
Kris Gevaert (additional)
Josef Kellermann (additional)
Wolfgang Voos (additional)
Albert Sickmann (additional)
Nikolaus Pfanner (additional)
Chris Meisinger (additional)

References 29 Referenced 471

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10.1074/jbc.270.45.27366 / J. Biol. Chem. / Prediction and identification of new natural substrates of the yeast mitochondrial intermediate peptidase by Branda (1995)
10.1111/j.1432-1033.1996.00779.x / Eur. J. Biochem. / Computational method to predict mitochondrially imported proteins and their targeting sequences by Claros (1996)
10.1126/science.1127895 / Science / Evolution of the molecular machines for protein import into mitochondria by Dolezal (2006)
10.1016/S0091-679X(01)65011-8 / Methods Cell Biol. / Analysis and prediction of mitochondrial targeting peptides by Emanuelsson (2001)
10.1038/nprot.2007.131 / Nat. Protocols / Locating proteins in the cell using TargetP, SignalP and related tools by Emanuelsson (2007)
10.1016/j.abb.2004.12.023 / Arch. Biochem. Biophys. / Aminopeptidase P isozyme expression in human tissues and peripheral blood mononuclear cell fractions by Ersahin (2005)
10.1016/S0022-2836(02)01000-8 / J. Mol. Biol. / A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1 by Esser (2002)
10.1016/S0167-4889(02)00265-3 / Biochim. Biophys. Acta / Mitochondrial processing peptidases by Gakh (2002)
10.1038/nbt810 / Nat. Biotechnol. / Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides by Gevaert (2003)
10.1107/S0907444904018724 / Acta Crystallogr. D Biol. Crystallogr. / Structure of Escherichia coli aminopeptidase P in complex with the inhibitor apstatin by Graham (2004)
10.1016/S0091-679X(06)80035-X / Methods Cell Biol. / Analysis and prediction of mitochondrial targeting signals by Habib (2007)
10.1515/BC.2006.107 / Biol. Chem. / Impact of the N-terminal amino acid on targeted protein degradation by Meinnel (2006)
10.1016/j.tcb.2007.02.001 / Trends Cell Biol. / The N-end rule pathway for regulated proteolysis: prokaryotic and eukaryotic strategies by Mogk (2007)
10.1146/annurev.biochem.76.052705.163409 / Annu. Rev. Biochem. / Translocation of proteins into mitochondria by Neupert (2007)
10.1016/j.cell.2005.08.003 / Cell / The m-AAA protease defective in hereditary spastic paraplegia controls ribosome assembly in mitochondria by Nolden (2005)
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10.1093/nar/gkm954 / Nucleic Acids Res. / MEROPS: the peptidase database by Rawlings (2008)
10.1021/pr050477f / J. Proteome Res. / Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics by Reinders (2006)
10.1002/(SICI)1097-0134(19980101)30:1<49::AID-PROT5>3.0.CO;2-F / Proteins / Feature-extraction from endopeptidase cleavage sites in mitochondrial targeting peptides by Schneider (1998)
10.1073/pnas.2135385100 / Proc. Natl. Acad. Sci. USA / The proteome of Saccharomyces cerevisiae mitochondria by Sickmann (2003)
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10.1038/sj.bjp.0704236 / Br. J. Pharmacol. / Apstatin, a selective inhibitor of aminopeptidase P, reduces myocardial infarct size by a kinin-dependent pathway by Wolfrum (2001)

Dates

Type	When
Created	15 years, 10 months ago (Oct. 16, 2009, 4:19 a.m.)
Deposited	2 years, 7 months ago (Jan. 28, 2023, 11:32 a.m.)
Indexed	1 week ago (Aug. 30, 2025, 12:43 p.m.)
Issued	15 years, 11 months ago (Oct. 1, 2009)
Published	15 years, 11 months ago (Oct. 1, 2009)
Published Print	15 years, 11 months ago (Oct. 1, 2009)

Funders 0

None

BibTeX

@article{V_gtle_2009, title={Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability}, volume={139}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/j.cell.2009.07.045}, DOI={10.1016/j.cell.2009.07.045}, number={2}, journal={Cell}, publisher={Elsevier BV}, author={Vögtle, F.-Nora and Wortelkamp, Stefanie and Zahedi, René P. and Becker, Dorothea and Leidhold, Claudia and Gevaert, Kris and Kellermann, Josef and Voos, Wolfgang and Sickmann, Albert and Pfanner, Nikolaus and Meisinger, Chris}, year={2009}, month=oct, pages={428–439} }

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