DOI: 10.1016/j.cell.2006.01.036. RNAi Components Are Required for Nuclear Clustering of Polycomb Group Response Elements

RNAi Components Are Required for Nuclear Clustering of Polycomb Group Response Elements

10.1016/j.cell.2006.01.036

Crossref journal-article

Elsevier BV

Cell (78)

Bibliography

Grimaud, C., Bantignies, F., Pal-Bhadra, M., Ghana, P., Bhadra, U., & Cavalli, G. (2006). RNAi Components Are Required for Nuclear Clustering of Polycomb Group Response Elements. Cell, 124(5), 957â971.

Authors 6

Charlotte Grimaud (first)
Frédéric Bantignies (additional)
Manika Pal-Bhadra (additional)
Pallavi Ghana (additional)
Utpal Bhadra (additional)
Giacomo Cavalli (additional)

References 55 Referenced 257

10.1046/j.1365-313x.2000.00908.x / Plant J. / Widely separated multiple transgene integration sites in wheat chromosomes are brought together at interphase by Abranches (2000)
10.1128/MCB.24.15.6742-6750.2004 / Mol. Cell. Biol. / Dissection of a natural RNA silencing process in the Drosophila melanogaster germ line by Aravin (2004)
10.1073/pnas.222671299 / Proc. Natl. Acad. Sci. USA / Characterization of the intergenic RNA profile at abdominal-A and Abdominal-B in the Drosophila bithorax complex by Bae (2002)
10.1101/gad.269503 / Genes Dev. / Inheritance of Polycomb-dependent chromosomal interactions in Drosophila by Bantignies (2003)
10.1083/jcb.141.2.469 / J. Cell Biol. / The distribution of polycomb-group proteins during cell division and development in Drosophila embryos: impact on models for silencing by Buchenau (1998)
10.1038/ng1602 / Nat. Genet. / Comprehensive analysis of heterochromatin- and RNAi-mediated epigenetic control of the fission yeast genome by Cam (2005)
10.1016/j.gde.2004.02.001 / Curr. Opin. Genet. Dev. / The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3 by Cao (2004)
10.1126/science.286.5441.955 / Science / Epigenetic inheritance of active chromatin after removal of the main transactivator by Cavalli (1999)
10.1002/j.1460-2075.1994.tb06545.x / EMBO J. / A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression by Chan (1994)
10.1242/dev.127.3.503 / Development / piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells by Cox (2000)
10.1007/3-540-27310-7_2 / Prog. Mol. Subcell. Biol. / Epigenetic inheritance of chromatin states mediated by Polycomb and trithorax group proteins in Drosophila by Dejardin (2005)
10.1038/nature03386 / Nature / Recruitment of Drosophila Polycomb group proteins to chromatin by DSP1 by Dejardin (2005)
10.1101/gad.7.8.1508 / Genes Dev. / polyhomeotic regulatory sequences induce developmental regulator-dependent variegation and targeted P-element insertions in Drosophila by Fauvarque (1993)
10.1242/dev.01950 / Development / Polycomb group protein complexes exchange rapidly in living Drosophila by Ficz (2005)
10.1038/ncb1155 / Nat. Cell Biol. / Dicer is essential for formation of the heterochromatin structure in vertebrate cells by Fukagawa (2004)
10.1016/j.ceb.2004.04.002 / Curr. Opin. Cell Biol. / Regulation of heterochromatin by histone methylation and small RNAs by Grewal (2004)
10.1126/science.1076466 / Science / Establishment and maintenance of a heterochromatin domain by Hall (2002)
10.1073/pnas.232688099 / Proc. Natl. Acad. Sci. USA / RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast by Hall (2003)
10.1126/science.286.5441.950 / Science / A species of small antisense RNA in posttranscriptional gene silencing in plants by Hamilton (1999)
10.1038/418244a / Nature / RNA interference by Hannon (2002)
10.1242/dev.128.14.2823 / Development / Aubergine encodes a Drosophila polar granule component required for pole cell formation and related to eIF2C by Harris (2001)
10.1126/science.1099035 / Science / RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins by Jia (2004)
10.1093/nar/gki323 / Nucleic Acids Res. / Argonaute protein PIWI controls mobilization of retrotransposons in the Drosophila male germline by Kalmykova (2005)
10.1101/gad.1248505 / Genes Dev. / Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing by Kanellopoulou (2005)
10.1016/S0065-2660(02)46015-4 / Adv. Genet. / Pairing-sensitive silencing, polycomb group response elements, and transposon homing in Drosophila by Kassis (2002)
{'key': '10.1016/j.cell.2006.01.036_bib26', 'first-page': '289', 'article-title': 'Combined immunostaining and FISH analysis of polytene chromosomes', 'volume': '247', 'author': 'Lavrov', 'year': '2004', 'journal-title': 'Methods Mol. Biol.'} / Methods Mol. Biol. / Combined immunostaining and FISH analysis of polytene chromosomes by Lavrov (2004)
10.1016/S0092-8674(04)00261-2 / Cell / Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways by Lee (2004)
10.1038/nature02875 / Nature / The role of RNA interference in heterochromatic silencing by Lippman (2004)
10.1073/pnas.92.18.8398 / Proc. Natl. Acad. Sci. USA / Complete sequence of the bithorax complex of Drosophila melanogaster by Martin (1995)
10.1038/nrg1500 / Nat. Rev. Genet. / RNAi-mediated pathways in the nucleus by Matzke (2005)
10.1242/dev.124.9.1809 / Development / In situ dissection of the Fab-7 region of the bithorax complex into a chromatin domain boundary and a Polycomb-response element by Mihaly (1997)
10.1101/gad.347005 / Genes Dev. / Synergistic recognition of an epigenetic DNA element by Pleiohomeotic and a Polycomb core complex by Mohd-Sarip (2005)
10.1093/genetics/153.3.1333 / Genetics / The mcp element from the Drosophila melanogaster bithorax complex mediates long-distance regulatory interactions by Muller (1999)
10.2307/3869076 / Plant Cell / Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans by Napoli (1990)
10.1038/ng1452 / Nat. Genet. / RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing by Noma (2004)
10.1101/gad.1210204 / Genes Dev. / Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways by Okamura (2004)
10.1093/emboj/17.17.5141 / EMBO J. / Binding of trithorax and Polycomb proteins to the bithorax complex: dynamic changes during early Drosophila embryogenesis by Orlando (1998)
10.1016/S0092-8674(00)80508-5 / Cell / Cosuppression in Drosophila: gene silencing of Alcohol dehydrogenase by white-Adh transgenes is Polycomb dependent by Pal-Bhadra (1997)
10.1016/S0092-8674(00)80060-4 / Cell / Cosuppression of nonhomologous transgenes in Drosophila involves mutually related endogenous sequences by Pal-Bhadra (1999)
10.1016/S1097-2765(02)00440-9 / Mol. Cell / RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila by Pal-Bhadra (2002)
10.1126/science.1092653 / Science / Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery by Pal-Bhadra (2004)
10.1016/0925-4773(93)90086-D / Mech. Dev. / The Polycomb gene is differentially regulated during oogenesis and embryogenesis of Drosophila melanogaster by Paro (1993)
10.1146/annurev.genet.38.072902.091907 / Annu. Rev. Genet. / Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins by Ringrose (2004)
10.1534/genetics.166.3.1313 / Genetics / Evidence for a piwi-dependent RNA silencing of the gypsy endogenous retrovirus by the Drosophila melanogaster flamenco gene by Sarot (2004)
10.1083/jcb.142.4.887 / J. Cell Biol. / The human polycomb group complex associates with pericentromeric heterochromatin to form a novel nuclear domain by Saurin (1998)
10.1101/gad.326205 / Genes Dev. / Intergenic transcription through a polycomb group response element counteracts silencing by Schmitt (2005)
10.1016/S0092-8674(00)80604-2 / Cell / Stabilization of chromatin structure by PRC1, a Polycomb complex by Shao (1999)
10.1101/gad.1228204 / Genes Dev. / YY1 DNA binding and PcG recruitment requires CtBP by Srinivasan (2004)
10.1073/pnas.0407641102 / Proc. Natl. Acad. Sci. USA / RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production by Sugiyama (2005)
10.1128/MCB.19.7.5189 / Mol. Cell. Biol. / Trithorax- and Polycomb-group response elements within an Ultrabithorax transcription maintenance unit consist of closely situated but separable sequences by Tillib (1999)
10.1016/S0092-8674(04)00218-1 / Cell / RISC assembly defects in the Drosophila RNAi mutant armitage by Tomari (2004)
10.1126/science.1093686 / Science / RNAi-mediated targeting of heterochromatin by the RITS complex by Verdel (2004)
10.1126/science.1074973 / Science / Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi by Volpe (2002)
10.1073/pnas.072190799 / Proc. Natl. Acad. Sci. USA / ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos by Williams (2002)
10.1002/j.1460-2075.1995.tb00253.x / EMBO J. / Drosophila Polycomb-group regulated chromatin inhibits the accessibility of a trans-activator to its target DNA by Zink (1995)

Dates

Type	When
Created	19 years, 5 months ago (March 10, 2006, 9:50 a.m.)
Deposited	2 years, 7 months ago (Jan. 28, 2023, 9:26 a.m.)
Indexed	1 month, 1 week ago (July 25, 2025, 6:28 a.m.)
Issued	19 years, 6 months ago (March 1, 2006)
Published	19 years, 6 months ago (March 1, 2006)
Published Print	19 years, 6 months ago (March 1, 2006)

Funders 0

None

BibTeX

@article{Grimaud_2006, title={RNAi Components Are Required for Nuclear Clustering of Polycomb Group Response Elements}, volume={124}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/j.cell.2006.01.036}, DOI={10.1016/j.cell.2006.01.036}, number={5}, journal={Cell}, publisher={Elsevier BV}, author={Grimaud, Charlotte and Bantignies, Frédéric and Pal-Bhadra, Manika and Ghana, Pallavi and Bhadra, Utpal and Cavalli, Giacomo}, year={2006}, month=mar, pages={957–971} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        7,
        25
      ]
    ],
    "date-time": "2025-07-25T10:28:38Z",
    "timestamp": 1753439318343
  },
  "reference-count": 55,
  "publisher": "Elsevier BV",
  "issue": "5",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2006,
            3,
            1
          ]
        ],
        "date-time": "2006-03-01T00:00:00Z",
        "timestamp": 1141171200000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    },
    {
      "start": {
        "date-parts": [
          [
            2013,
            7,
            17
          ]
        ],
        "date-time": "2013-07-17T00:00:00Z",
        "timestamp": 1374019200000
      },
      "content-version": "vor",
      "delay-in-days": 2695,
      "URL": "http://www.elsevier.com/open-access/userlicense/1.0/"
    },
    {
      "start": {
        "date-parts": [
          [
            2006,
            3,
            1
          ]
        ],
        "date-time": "2006-03-01T00:00:00Z",
        "timestamp": 1141171200000
      },
      "content-version": "stm-asf",
      "delay-in-days": 0,
      "URL": "https://doi.org/10.15223/policy-017"
    },
    {
      "start": {
        "date-parts": [
          [
            2006,
            3,
            1
          ]
        ],
        "date-time": "2006-03-01T00:00:00Z",
        "timestamp": 1141171200000
      },
      "content-version": "stm-asf",
      "delay-in-days": 0,
      "URL": "https://doi.org/10.15223/policy-037"
    },
    {
      "start": {
        "date-parts": [
          [
            2006,
            3,
            1
          ]
        ],
        "date-time": "2006-03-01T00:00:00Z",
        "timestamp": 1141171200000
      },
      "content-version": "stm-asf",
      "delay-in-days": 0,
      "URL": "https://doi.org/10.15223/policy-012"
    },
    {
      "start": {
        "date-parts": [
          [
            2006,
            3,
            1
          ]
        ],
        "date-time": "2006-03-01T00:00:00Z",
        "timestamp": 1141171200000
      },
      "content-version": "stm-asf",
      "delay-in-days": 0,
      "URL": "https://doi.org/10.15223/policy-029"
    },
    {
      "start": {
        "date-parts": [
          [
            2006,
            3,
            1
          ]
        ],
        "date-time": "2006-03-01T00:00:00Z",
        "timestamp": 1141171200000
      },
      "content-version": "stm-asf",
      "delay-in-days": 0,
      "URL": "https://doi.org/10.15223/policy-004"
    }
  ],
  "content-domain": {
    "domain": [
      "cell.com",
      "elsevier.com",
      "sciencedirect.com"
    ],
    "crossmark-restriction": true
  },
  "published-print": {
    "date-parts": [
      [
        2006,
        3
      ]
    ]
  },
  "DOI": "10.1016/j.cell.2006.01.036",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2006,
        3,
        10
      ]
    ],
    "date-time": "2006-03-10T14:50:21Z",
    "timestamp": 1142002221000
  },
  "page": "957-971",
  "update-policy": "http://dx.doi.org/10.1016/elsevier_cm_policy",
  "source": "Crossref",
  "is-referenced-by-count": 257,
  "title": "RNAi Components Are Required for Nuclear Clustering of Polycomb Group Response Elements",
  "prefix": "10.1016",
  "volume": "124",
  "author": [
    {
      "given": "Charlotte",
      "family": "Grimaud",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Fr\u00e9d\u00e9ric",
      "family": "Bantignies",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Manika",
      "family": "Pal-Bhadra",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Pallavi",
      "family": "Ghana",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Utpal",
      "family": "Bhadra",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Giacomo",
      "family": "Cavalli",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/j.cell.2006.01.036_bib1",
      "doi-asserted-by": "crossref",
      "first-page": "713",
      "DOI": "10.1046/j.1365-313x.2000.00908.x",
      "article-title": "Widely separated multiple transgene integration sites in wheat chromosomes are brought together at interphase",
      "volume": "24",
      "author": "Abranches",
      "year": "2000",
      "journal-title": "Plant J."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib2",
      "doi-asserted-by": "crossref",
      "first-page": "6742",
      "DOI": "10.1128/MCB.24.15.6742-6750.2004",
      "article-title": "Dissection of a natural RNA silencing process in the Drosophila melanogaster germ line",
      "volume": "24",
      "author": "Aravin",
      "year": "2004",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib3",
      "doi-asserted-by": "crossref",
      "first-page": "16847",
      "DOI": "10.1073/pnas.222671299",
      "article-title": "Characterization of the intergenic RNA profile at abdominal-A and Abdominal-B in the Drosophila bithorax complex",
      "volume": "99",
      "author": "Bae",
      "year": "2002",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib4",
      "doi-asserted-by": "crossref",
      "first-page": "2406",
      "DOI": "10.1101/gad.269503",
      "article-title": "Inheritance of Polycomb-dependent chromosomal interactions in Drosophila",
      "volume": "17",
      "author": "Bantignies",
      "year": "2003",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib5",
      "doi-asserted-by": "crossref",
      "first-page": "469",
      "DOI": "10.1083/jcb.141.2.469",
      "article-title": "The distribution of polycomb-group proteins during cell division and development in Drosophila embryos: impact on models for silencing",
      "volume": "141",
      "author": "Buchenau",
      "year": "1998",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib6",
      "doi-asserted-by": "crossref",
      "first-page": "809",
      "DOI": "10.1038/ng1602",
      "article-title": "Comprehensive analysis of heterochromatin- and RNAi-mediated epigenetic control of the fission yeast genome",
      "volume": "37",
      "author": "Cam",
      "year": "2005",
      "journal-title": "Nat. Genet."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "155",
      "DOI": "10.1016/j.gde.2004.02.001",
      "article-title": "The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3",
      "volume": "14",
      "author": "Cao",
      "year": "2004",
      "journal-title": "Curr. Opin. Genet. Dev."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib8",
      "doi-asserted-by": "crossref",
      "first-page": "955",
      "DOI": "10.1126/science.286.5441.955",
      "article-title": "Epigenetic inheritance of active chromatin after removal of the main transactivator",
      "volume": "286",
      "author": "Cavalli",
      "year": "1999",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "2553",
      "DOI": "10.1002/j.1460-2075.1994.tb06545.x",
      "article-title": "A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression",
      "volume": "13",
      "author": "Chan",
      "year": "1994",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "503",
      "DOI": "10.1242/dev.127.3.503",
      "article-title": "piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells",
      "volume": "127",
      "author": "Cox",
      "year": "2000",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib11",
      "doi-asserted-by": "crossref",
      "first-page": "31",
      "DOI": "10.1007/3-540-27310-7_2",
      "article-title": "Epigenetic inheritance of chromatin states mediated by Polycomb and trithorax group proteins in Drosophila",
      "volume": "38",
      "author": "Dejardin",
      "year": "2005",
      "journal-title": "Prog. Mol. Subcell. Biol."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "533",
      "DOI": "10.1038/nature03386",
      "article-title": "Recruitment of Drosophila Polycomb group proteins to chromatin by DSP1",
      "volume": "434",
      "author": "Dejardin",
      "year": "2005",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "1508",
      "DOI": "10.1101/gad.7.8.1508",
      "article-title": "polyhomeotic regulatory sequences induce developmental regulator-dependent variegation and targeted P-element insertions in Drosophila",
      "volume": "7",
      "author": "Fauvarque",
      "year": "1993",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib14",
      "doi-asserted-by": "crossref",
      "first-page": "3963",
      "DOI": "10.1242/dev.01950",
      "article-title": "Polycomb group protein complexes exchange rapidly in living Drosophila",
      "volume": "132",
      "author": "Ficz",
      "year": "2005",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "784",
      "DOI": "10.1038/ncb1155",
      "article-title": "Dicer is essential for formation of the heterochromatin structure in vertebrate cells",
      "volume": "6",
      "author": "Fukagawa",
      "year": "2004",
      "journal-title": "Nat. Cell Biol."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib16",
      "doi-asserted-by": "crossref",
      "first-page": "230",
      "DOI": "10.1016/j.ceb.2004.04.002",
      "article-title": "Regulation of heterochromatin by histone methylation and small RNAs",
      "volume": "16",
      "author": "Grewal",
      "year": "2004",
      "journal-title": "Curr. Opin. Cell Biol."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib17",
      "doi-asserted-by": "crossref",
      "first-page": "2232",
      "DOI": "10.1126/science.1076466",
      "article-title": "Establishment and maintenance of a heterochromatin domain",
      "volume": "297",
      "author": "Hall",
      "year": "2002",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "193",
      "DOI": "10.1073/pnas.232688099",
      "article-title": "RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast",
      "volume": "100",
      "author": "Hall",
      "year": "2003",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "950",
      "DOI": "10.1126/science.286.5441.950",
      "article-title": "A species of small antisense RNA in posttranscriptional gene silencing in plants",
      "volume": "286",
      "author": "Hamilton",
      "year": "1999",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "244",
      "DOI": "10.1038/418244a",
      "article-title": "RNA interference",
      "volume": "418",
      "author": "Hannon",
      "year": "2002",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "2823",
      "DOI": "10.1242/dev.128.14.2823",
      "article-title": "Aubergine encodes a Drosophila polar granule component required for pole cell formation and related to eIF2C",
      "volume": "128",
      "author": "Harris",
      "year": "2001",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "1971",
      "DOI": "10.1126/science.1099035",
      "article-title": "RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins",
      "volume": "304",
      "author": "Jia",
      "year": "2004",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "2052",
      "DOI": "10.1093/nar/gki323",
      "article-title": "Argonaute protein PIWI controls mobilization of retrotransposons in the Drosophila male germline",
      "volume": "33",
      "author": "Kalmykova",
      "year": "2005",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "489",
      "DOI": "10.1101/gad.1248505",
      "article-title": "Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing",
      "volume": "19",
      "author": "Kanellopoulou",
      "year": "2005",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "421",
      "DOI": "10.1016/S0065-2660(02)46015-4",
      "article-title": "Pairing-sensitive silencing, polycomb group response elements, and transposon homing in Drosophila",
      "volume": "46",
      "author": "Kassis",
      "year": "2002",
      "journal-title": "Adv. Genet."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib26",
      "first-page": "289",
      "article-title": "Combined immunostaining and FISH analysis of polytene chromosomes",
      "volume": "247",
      "author": "Lavrov",
      "year": "2004",
      "journal-title": "Methods Mol. Biol."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib27",
      "doi-asserted-by": "crossref",
      "first-page": "69",
      "DOI": "10.1016/S0092-8674(04)00261-2",
      "article-title": "Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways",
      "volume": "117",
      "author": "Lee",
      "year": "2004",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "364",
      "DOI": "10.1038/nature02875",
      "article-title": "The role of RNA interference in heterochromatic silencing",
      "volume": "431",
      "author": "Lippman",
      "year": "2004",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "8398",
      "DOI": "10.1073/pnas.92.18.8398",
      "article-title": "Complete sequence of the bithorax complex of Drosophila melanogaster",
      "volume": "92",
      "author": "Martin",
      "year": "1995",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "24",
      "DOI": "10.1038/nrg1500",
      "article-title": "RNAi-mediated pathways in the nucleus",
      "volume": "6",
      "author": "Matzke",
      "year": "2005",
      "journal-title": "Nat. Rev. Genet."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "1809",
      "DOI": "10.1242/dev.124.9.1809",
      "article-title": "In situ dissection of the Fab-7 region of the bithorax complex into a chromatin domain boundary and a Polycomb-response element",
      "volume": "124",
      "author": "Mihaly",
      "year": "1997",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "1755",
      "DOI": "10.1101/gad.347005",
      "article-title": "Synergistic recognition of an epigenetic DNA element by Pleiohomeotic and a Polycomb core complex",
      "volume": "19",
      "author": "Mohd-Sarip",
      "year": "2005",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "1333",
      "DOI": "10.1093/genetics/153.3.1333",
      "article-title": "The mcp element from the Drosophila melanogaster bithorax complex mediates long-distance regulatory interactions",
      "volume": "153",
      "author": "Muller",
      "year": "1999",
      "journal-title": "Genetics"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "279",
      "DOI": "10.2307/3869076",
      "article-title": "Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans",
      "volume": "2",
      "author": "Napoli",
      "year": "1990",
      "journal-title": "Plant Cell"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "1174",
      "DOI": "10.1038/ng1452",
      "article-title": "RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing",
      "volume": "36",
      "author": "Noma",
      "year": "2004",
      "journal-title": "Nat. Genet."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "1655",
      "DOI": "10.1101/gad.1210204",
      "article-title": "Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways",
      "volume": "18",
      "author": "Okamura",
      "year": "2004",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib37",
      "doi-asserted-by": "crossref",
      "first-page": "5141",
      "DOI": "10.1093/emboj/17.17.5141",
      "article-title": "Binding of trithorax and Polycomb proteins to the bithorax complex: dynamic changes during early Drosophila embryogenesis",
      "volume": "17",
      "author": "Orlando",
      "year": "1998",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib38",
      "doi-asserted-by": "crossref",
      "first-page": "479",
      "DOI": "10.1016/S0092-8674(00)80508-5",
      "article-title": "Cosuppression in Drosophila: gene silencing of Alcohol dehydrogenase by white-Adh transgenes is Polycomb dependent",
      "volume": "90",
      "author": "Pal-Bhadra",
      "year": "1997",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib39",
      "doi-asserted-by": "crossref",
      "first-page": "35",
      "DOI": "10.1016/S0092-8674(00)80060-4",
      "article-title": "Cosuppression of nonhomologous transgenes in Drosophila involves mutually related endogenous sequences",
      "volume": "99",
      "author": "Pal-Bhadra",
      "year": "1999",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib40",
      "doi-asserted-by": "crossref",
      "first-page": "315",
      "DOI": "10.1016/S1097-2765(02)00440-9",
      "article-title": "RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila",
      "volume": "9",
      "author": "Pal-Bhadra",
      "year": "2002",
      "journal-title": "Mol. Cell"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib41",
      "doi-asserted-by": "crossref",
      "first-page": "669",
      "DOI": "10.1126/science.1092653",
      "article-title": "Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery",
      "volume": "303",
      "author": "Pal-Bhadra",
      "year": "2004",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib42",
      "doi-asserted-by": "crossref",
      "first-page": "37",
      "DOI": "10.1016/0925-4773(93)90086-D",
      "article-title": "The Polycomb gene is differentially regulated during oogenesis and embryogenesis of Drosophila melanogaster",
      "volume": "40",
      "author": "Paro",
      "year": "1993",
      "journal-title": "Mech. Dev."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib43",
      "doi-asserted-by": "crossref",
      "first-page": "413",
      "DOI": "10.1146/annurev.genet.38.072902.091907",
      "article-title": "Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins",
      "volume": "38",
      "author": "Ringrose",
      "year": "2004",
      "journal-title": "Annu. Rev. Genet."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib44",
      "doi-asserted-by": "crossref",
      "first-page": "1313",
      "DOI": "10.1534/genetics.166.3.1313",
      "article-title": "Evidence for a piwi-dependent RNA silencing of the gypsy endogenous retrovirus by the Drosophila melanogaster flamenco gene",
      "volume": "166",
      "author": "Sarot",
      "year": "2004",
      "journal-title": "Genetics"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib45",
      "doi-asserted-by": "crossref",
      "first-page": "887",
      "DOI": "10.1083/jcb.142.4.887",
      "article-title": "The human polycomb group complex associates with pericentromeric heterochromatin to form a novel nuclear domain",
      "volume": "142",
      "author": "Saurin",
      "year": "1998",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib46",
      "doi-asserted-by": "crossref",
      "first-page": "697",
      "DOI": "10.1101/gad.326205",
      "article-title": "Intergenic transcription through a polycomb group response element counteracts silencing",
      "volume": "19",
      "author": "Schmitt",
      "year": "2005",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib47",
      "doi-asserted-by": "crossref",
      "first-page": "37",
      "DOI": "10.1016/S0092-8674(00)80604-2",
      "article-title": "Stabilization of chromatin structure by PRC1, a Polycomb complex",
      "volume": "98",
      "author": "Shao",
      "year": "1999",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib48",
      "doi-asserted-by": "crossref",
      "first-page": "2596",
      "DOI": "10.1101/gad.1228204",
      "article-title": "YY1 DNA binding and PcG recruitment requires CtBP",
      "volume": "18",
      "author": "Srinivasan",
      "year": "2004",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib49",
      "doi-asserted-by": "crossref",
      "first-page": "152",
      "DOI": "10.1073/pnas.0407641102",
      "article-title": "RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production",
      "volume": "102",
      "author": "Sugiyama",
      "year": "2005",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib50",
      "doi-asserted-by": "crossref",
      "first-page": "5189",
      "DOI": "10.1128/MCB.19.7.5189",
      "article-title": "Trithorax- and Polycomb-group response elements within an Ultrabithorax transcription maintenance unit consist of closely situated but separable sequences",
      "volume": "19",
      "author": "Tillib",
      "year": "1999",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib51",
      "doi-asserted-by": "crossref",
      "first-page": "831",
      "DOI": "10.1016/S0092-8674(04)00218-1",
      "article-title": "RISC assembly defects in the Drosophila RNAi mutant armitage",
      "volume": "116",
      "author": "Tomari",
      "year": "2004",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib52",
      "doi-asserted-by": "crossref",
      "first-page": "672",
      "DOI": "10.1126/science.1093686",
      "article-title": "RNAi-mediated targeting of heterochromatin by the RITS complex",
      "volume": "303",
      "author": "Verdel",
      "year": "2004",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib53",
      "doi-asserted-by": "crossref",
      "first-page": "1833",
      "DOI": "10.1126/science.1074973",
      "article-title": "Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi",
      "volume": "297",
      "author": "Volpe",
      "year": "2002",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib54",
      "doi-asserted-by": "crossref",
      "first-page": "6889",
      "DOI": "10.1073/pnas.072190799",
      "article-title": "ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos",
      "volume": "99",
      "author": "Williams",
      "year": "2002",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/j.cell.2006.01.036_bib55",
      "doi-asserted-by": "crossref",
      "first-page": "5660",
      "DOI": "10.1002/j.1460-2075.1995.tb00253.x",
      "article-title": "Drosophila Polycomb-group regulated chromatin inhibits the accessibility of a trans-activator to its target DNA",
      "volume": "14",
      "author": "Zink",
      "year": "1995",
      "journal-title": "EMBO J."
    }
  ],
  "container-title": "Cell",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0092867406001711?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0092867406001711?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        1,
        28
      ]
    ],
    "date-time": "2023-01-28T14:26:07Z",
    "timestamp": 1674915967000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0092867406001711"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2006,
        3
      ]
    ]
  },
  "references-count": 55,
  "journal-issue": {
    "issue": "5",
    "published-print": {
      "date-parts": [
        [
          2006,
          3
        ]
      ]
    }
  },
  "alternative-id": [
    "S0092867406001711"
  ],
  "URL": "http://dx.doi.org/10.1016/j.cell.2006.01.036",
  "relation": {
    "has-review": [
      {
        "id-type": "doi",
        "id": "10.3410/f.1006159.374008",
        "asserted-by": "object"
      }
    ]
  },
  "ISSN": [
    "0092-8674"
  ],
  "subject": [],
  "container-title-short": "Cell",
  "published": {
    "date-parts": [
      [
        2006,
        3
      ]
    ]
  },
  "assertion": [
    {
      "value": "Elsevier",
      "name": "publisher",
      "label": "This article is maintained by"
    },
    {
      "value": "RNAi Components Are Required for Nuclear Clustering of Polycomb Group Response Elements",
      "name": "articletitle",
      "label": "Article Title"
    },
    {
      "value": "Cell",
      "name": "journaltitle",
      "label": "Journal Title"
    },
    {
      "value": "https://doi.org/10.1016/j.cell.2006.01.036",
      "name": "articlelink",
      "label": "CrossRef DOI link to publisher maintained version"
    },
    {
      "value": "article",
      "name": "content_type",
      "label": "Content Type"
    },
    {
      "value": "Copyright \u00a9 2006 Elsevier Inc. All rights reserved.",
      "name": "copyright",
      "label": "Copyright"
    }
  ]
}