DOI: 10.1016/j.cell.2005.02.020. hDOT1L Links Histone Methylation to Leukemogenesis

hDOT1L Links Histone Methylation to Leukemogenesis

10.1016/j.cell.2005.02.020

Crossref journal-article

Elsevier BV

Cell (78)

Bibliography

Okada, Y., Feng, Q., Lin, Y., Jiang, Q., Li, Y., Coffield, V. M., Su, L., Xu, G., & Zhang, Y. (2005). hDOT1L Links Histone Methylation to Leukemogenesis. Cell, 121(2), 167â178.

Authors 9

Yuki Okada (first)
Qin Feng (additional)
Yihui Lin (additional)
Qi Jiang (additional)
Yaqiang Li (additional)
Vernon M. Coffield (additional)
Lishan Su (additional)
Guoliang Xu (additional)
Yi Zhang (additional)

References 35 Referenced 704

10.1038/sj.onc.1204639 / Oncogene / Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins by Ayton (2001)
10.1101/gad.1111603 / Genes Dev. / Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9 by Ayton (2003)
10.1093/emboj/cdg542 / EMBO J. / EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer by Bracken (2003)
{'key': '10.1016/j.cell.2005.02.020_bib4', 'first-page': '301', 'article-title': 'Homeobox genes in leukemogenesis', 'volume': '71', 'author': 'Buske', 'year': '2000', 'journal-title': 'Int. J. Hematol.'} / Int. J. Hematol. / Homeobox genes in leukemogenesis by Buske (2000)
10.1038/sj.leu.2401933 / Leukemia / The amino terminus targets the mixed lineage leukemia (MLL) protein to the nucleolus, nuclear matrix and mitotic chromosomal scaffolds by Caslini (2000)
10.1182/blood.V86.6.2073.bloodjournal8662073 / Blood / The t(10;11) translocation in acute myeloid leukemia (M5) consistently fuses the leucine zipper motif of AF10 onto the HRX gene by Chaplin (1995)
10.1038/nbt889 / Nat. Biotechnol. / A genetic approach to inactivating chemokine receptors using a modified viral protein by Coffield (2003)
10.1101/gad.1195504 / Genes Dev. / Extending the repertoire of the mixed-lineage leukemia gene MLL in leukemogenesis by Daser (2004)
10.1046/j.1365-2141.1999.01439.x / Br. J. Haematol. / Mll rearrangements in haematological malignancies: lessons from clinical and biological studies by Dimartino (1999)
10.1182/blood.V99.10.3780 / Blood / The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10 by DiMartino (2002)
10.1073/pnas.93.10.4804 / Proc. Natl. Acad. Sci. USA / The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family by Dreyling (1996)
10.1016/S0960-9822(02)00901-6 / Curr. Biol. / Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain by Feng (2002)
10.1126/science.286.5439.531 / Science / Molecular classification of cancer: class discovery and class prediction by gene expression monitoring by Golub (1999)
10.1016/S0092-8674(03)00816-X / Cell / Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression by Hsieh (2003)
10.1016/S1097-2765(04)00081-4 / Mol. Cell / Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus by Hughes (2004)
10.1073/pnas.1933744100 / Proc. Natl. Acad. Sci. USA / EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells by Kleer (2003)
10.1093/emboj/17.13.3714 / EMBO J. / Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b by Kroon (1998)
10.1242/jcs.00493 / J. Cell Sci. / An epigenetic road map for histone lysine methylation by Lachner (2003)
10.1016/S1097-2765(02)00741-4 / Mol. Cell / MLL targets SET domain methyltransferase activity to Hox gene promoters by Milne (2002)
10.1016/S0092-8674(03)00114-4 / Cell / Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase by Min (2003)
10.1101/gad.269603 / Genes Dev. / Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27 by Min (2003)
{'key': '10.1016/j.cell.2005.02.020_bib22', 'first-page': '2235', 'article-title': 'Identification of a new family of Pbx-related homeobox genes', 'volume': '13', 'author': 'Nakamura', 'year': '1996', 'journal-title': 'Oncogene'} / Oncogene / Identification of a new family of Pbx-related homeobox genes by Nakamura (1996)
10.1016/S1097-2765(02)00740-2 / Mol. Cell / ALL-1 Is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation by Nakamura (2002)
10.1101/gad.1001502 / Genes Dev. / Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association by Ng (2002)
10.1038/nature01080 / Nature / Active genes are tri-methylated at K4 of histone H3 by Santos-Rosa (2002)
10.1073/pnas.91.25.12223 / Proc. Natl. Acad. Sci. USA / Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells by Sauvageau (1994)
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10.1038/47412 / Nature / The language of covalent histone modifications by Strahl (2000)
10.1016/S0092-8674(02)00759-6 / Cell / Dot1p modulates silencing in yeast by methylation of the nucleosome core by van Leeuwen (2002)
10.1038/nature01075 / Nature / The polycomb group protein EZH2 is involved in progression of prostate cancer by Varambally (2002)
10.1182/blood-2002-04-1015 / Blood / Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties by Yokoyama (2002)
10.1128/MCB.24.13.5639-5649.2004 / Mol. Cell. Biol. / Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression by Yokoyama (2004)
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Dates

Type	When
Created	20 years, 4 months ago (April 22, 2005, 9:32 a.m.)
Deposited	5 years, 4 months ago (April 6, 2020, 9:45 p.m.)
Indexed	2 weeks, 6 days ago (Aug. 1, 2025, 11:59 p.m.)
Issued	20 years, 4 months ago (April 1, 2005)
Published	20 years, 4 months ago (April 1, 2005)
Published Print	20 years, 4 months ago (April 1, 2005)

Funders 0

None

BibTeX

@article{Okada_2005, title={hDOT1L Links Histone Methylation to Leukemogenesis}, volume={121}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/j.cell.2005.02.020}, DOI={10.1016/j.cell.2005.02.020}, number={2}, journal={Cell}, publisher={Elsevier BV}, author={Okada, Yuki and Feng, Qin and Lin, Yihui and Jiang, Qi and Li, Yaqiang and Coffield, Vernon M. and Su, Lishan and Xu, Guoliang and Zhang, Yi}, year={2005}, month=apr, pages={167–178} }

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