Crossref
journal-article
Elsevier BV
Cell (78)
References
53
Referenced
381
10.1038/ncb1202-e277
/ Nat. Cell Biol. / Checkpoint signalling by Abraham (2002)10.1038/nature01368
/ Nature / DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation by Bakkenist (2003)10.1073/pnas.95.24.14066
/ Proc. Natl. Acad. Sci. USA / DNA end-joining catalyzed by human cell-free extracts by Baumann (1998)10.1016/S0968-0004(00)01563-2
/ Trends Biochem. Sci. / Fat by Bosotti (2000)10.1016/j.molcel.2004.05.005
/ Mol. Cell / The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells by Brumbaugh (2004)10.1074/jbc.272.51.32547
/ J. Biol. Chem. / The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus by Brunn (1997)10.1126/science.281.5383.1677
/ Science / Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 by Canman (1998)10.1093/emboj/cdg630
/ EMBO J. / The Mre11 complex is required for ATM activation and the G2/M checkpoint by Carson (2003)10.1074/jbc.275.11.7803
/ J. Biol. Chem. / Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase by Chan (2000)10.1101/gad.1015202
/ Genes Dev. / Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks by Chan (2002)10.1093/emboj/17.1.159
/ EMBO J. / Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints by Cliby (1998)10.1126/science.1065521
/ Science / Atr and atrip by Cortez (2001)10.1093/emboj/cdf299
/ EMBO J. / Synapsis of DNA ends by DNA-dependent protein kinase by DeFazio (2002)10.1126/science.1063518
/ Science / Mammalian TOR by Dennis (2001){'key': '10.1016/j.cell.2004.06.023_BIB15', 'first-page': '243', 'article-title': 'Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase.Biochem', 'volume': '368', 'author': 'Douglas', 'year': '2002', 'journal-title': 'ET J.'}
/ ET J. / Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase.Biochem by Douglas (2002)10.1371/journal.pbio.0000033
/ PLoS Biol. / Biochemical characterization of DNA damage checkpoint complexes by Ellison (2003)10.1016/0092-8674(93)90057-W
/ Cell / The DNA-dependent protein kinase by Gottlieb (1993)10.1093/emboj/21.8.2038
/ EMBO J. / Specific interaction of IP6 with human Ku70/80, the DNA-binding subunit of DNA-PK by Hanakahi (2002)10.1016/S0092-8674(00)00061-1
/ Cell / Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair by Hanakahi (2000)10.1016/S0092-8674(02)00833-4
/ Cell / Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action by Hara (2002)10.1016/S0960-9822(00)00855-1
/ Curr. Biol. / Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint by Hekmat-Nejad (2000)10.1038/sj.onc.1207447
/ Oncogene / Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation by Horejsi (2004)10.1016/S0092-8674(02)00741-9
/ Cell / The conformational plasticity of protein kinases by Huse (2002)10.1016/S0092-8674(03)00929-2
/ Cell / TSC2 mediates cellular energy response to control cell growth and survival by Inoki (2003)10.1038/35043058
/ Nat. Rev. Mol. Cell Biol. / The many substrates and functions of ATM by Kastan (2000)10.1074/jbc.274.53.37538
/ J. Biol. Chem. / Substrate specificities and identification of putative substrates of ATM kinase family members by Kim (1999)10.1016/S0092-8674(02)00808-5
/ Cell / mTOR interacts with Raptor to form a nutrient-sensitive complex that signals to the cell growth machinery by Kim (2002)10.1016/S1097-2765(03)00114-X
/ Mol. Cell / GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between Raptor and mTOR by Kim (2003)10.1101/gad.1200304
/ Genes Dev. / Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway by Kitagawa (2004)10.1126/science.1091496
/ Science / Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex by Lee (2004)10.1073/pnas.0401847101
/ Proc. Natl. Acad. Sci. USA / Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation by Lin (2004){'key': '10.1016/j.cell.2004.06.023_BIB32', 'first-page': '990', 'article-title': 'DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology', 'volume': '61', 'author': 'Lukas', 'year': '2001', 'journal-title': 'Cancer Res.'}
/ Cancer Res. / DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology by Lukas (2001)10.1038/ncb945
/ Nat. Cell Biol. / Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage by Lukas (2003)10.1101/gad.1013502
/ Genes Dev. / A requirement for replication in activation of the ATR-dependent DNA damage checkpoint by Lupardus (2002)10.1074/jbc.C200030200
/ J. Biol. Chem. / Binding of inositol hexakisphosphate (IP6) to Ku but not to DNA-PKcs by Ma (2002)10.1126/science.1075762
/ Science / The protein kinase complement of the human genome by Manning (2002)10.1038/86920
/ Nat. Genet. / An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele by Maser (2001)10.1126/science.289.5487.2133
/ Science / Activation of the DNA replication checkpoint through RNA synthesis by primase by Michael (2000){'key': '10.1016/j.cell.2004.06.023_BIB39', 'first-page': '8586', 'article-title': '53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage', 'volume': '63', 'author': 'Mochan', 'year': '2003', 'journal-title': 'Cancer Res.'}
/ Cancer Res. / 53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage by Mochan (2003)10.1101/gad.1099003
/ Genes Dev. / ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism by Nakada (2003)10.1038/ng1129
/ Nat. Genet. / A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome by O'Driscoll (2003)10.1016/S0962-8924(02)02380-2
/ Trends Cell Biol. / Checking on the fork by Osborn (2002)10.1016/S0955-0674(00)00091-0
/ Curr. Opin. Cell Biol. / The Mre11 complex and ATM by Petrini (2002)10.1016/S0021-9258(19)37629-X
/ J. Biol. Chem. / Nonenzymatic phosphorylation of tyrosine and serine by ATP is catalyzed by manganese but not magnesium by Schieven (1988)10.4161/cc.3.7.972
/ Cell Cycle / ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage by Sorensen (2004)10.1016/S1097-2765(03)00455-6
/ Mol. Cell / Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice by Theunissen (2003)10.1128/MCB.24.3.1292-1300.2003
/ Mol. Cell. Biol. / Quaternary structure of ATR and effects of ATRIP and replication protein A on its DNA binding and kinase activities by Unsal-Kacmaz (2004)10.1093/emboj/cdg541
/ EMBO J. / Requirement of the MRN complex for ATM activation by DNA damage by Uziel (2003)10.1038/46319
/ Nature / Structural insights into phosphoinositide 3-kinase catalysis and signalling by Walker (1999)10.1038/35088000
/ Nature / Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair by Walker (2001)10.1128/MCB.23.7.2556-2563.2003
/ Mol. Cell. Biol. / p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice by Ward (2003)10.1101/gad.913001
/ Genes Dev. / Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay by Yamashita (2001)10.1126/science.1083430
/ Science / Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes by Zou (2003)
Dates
Type | When |
---|---|
Created | 21 years, 1 month ago (July 10, 2004, 10:55 a.m.) |
Deposited | 2 years, 7 months ago (Jan. 28, 2023, 10:06 a.m.) |
Indexed | 2 months, 2 weeks ago (June 14, 2025, 12:24 a.m.) |
Issued | 21 years, 1 month ago (July 1, 2004) |
Published | 21 years, 1 month ago (July 1, 2004) |
Published Print | 21 years, 1 month ago (July 1, 2004) |
@article{Bakkenist_2004, title={Initiating Cellular Stress Responses}, volume={118}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/j.cell.2004.06.023}, DOI={10.1016/j.cell.2004.06.023}, number={1}, journal={Cell}, publisher={Elsevier BV}, author={Bakkenist, Christopher J and Kastan, Michael B}, year={2004}, month=jul, pages={9–17} }