DOI: 10.1016/j.brainres.2009.03.024. HIV-1 Vpr deregulates calcium secretion in neural cells

HIV-1 Vpr deregulates calcium secretion in neural cells

10.1016/j.brainres.2009.03.024

Crossref journal-article

Elsevier BV

Brain Research (78)

Bibliography

Rom, I., Deshmane, S. L., Mukerjee, R., Khalili, K., Amini, S., & Sawaya, B. E. (2009). HIV-1 Vpr deregulates calcium secretion in neural cells. Brain Research, 1275, 81â86.

Authors 6

Inna Rom (first)
Satish L. Deshmane (additional)
Ruma Mukerjee (additional)
Kamel Khalili (additional)
Shohreh Amini (additional)
Bassel E. Sawaya (additional)

References 35 Referenced 36

10.1074/jbc.M403792200 / J. Biol. Chem. / Interplay between HIV-1 Vpr and Sp1 modulates p21WAF1 gene expression in human astrocytes by Amini (2004)
10.1128/MCB.25.18.8126-8138.2005 / Mol. Cell. Biol. / p73 interacts with HIV-1 Tat in astrocytic cells and prevents its acetylation on Lys28 by Amini (2005)
10.1038/351751a0 / Nature / Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum by Bezprozvanny (1991)
10.1111/j.1749-6632.2002.tb04762.x / Ann. N.Y. Acad. Sci. / Na/Ca exchanger and PMCA localization in neurons and astrocytes: functional implications by Blaustein (2002)
10.4161/cc.3.3.705 / Cell Cycle / Apoptosis and calcium: new roles for cytochrome c and inositol 1,4,5-trisphosphate by Boehning (2004)
10.1073/pnas.0409650102 / Proc. Natl. Acad. Sci. U. S. A. / A peptide inhibitor of cytochrome c/inositol 1,4,5-trisphosphate receptor binding blocks intrinsic and extrinsic cell death pathways by Boehning (2005)
10.1074/jbc.M602249200 / J. Biol. Chem. / Messenger-specific role for nicotinic acid adenine dinucleotide phosphate in neuronal differentiation by Brailoiu (2006)
10.1152/ajpcell.00139.2004 / Am. J. Physiol., Cell Physiol. / Calcium, ATP, and ROS: a mitochondrial love-hate triangle by Brookes (2004)
10.1016/j.neuroscience.2006.01.034 / Neuroscience / Differences in mitochondrial movement and morphology in young and mature primary cortical neurons in culture by Chang (2006)
10.1007/s11064-008-9694-9 / Neurochem. Res. / Metabotropic glutamate receptors in glial cells by D'Antoni (2008)
10.1146/annurev.pathol.1.110304.100218 / Annu. Rev. Pathol. / Calcium in cell injury and death by Dong (2006)
10.1006/mcne.2002.1196 / Mol. Cell. Neurosci. / Lithium ameliorates HIV-gp120-mediated neurotoxicity by Everall (2002)
10.1152/physrev.00013.2002 / Physiol. Rev. / Ryanodine receptor calcium release channels by Fill (2002)
10.2741/Garcia / Front. Biosci. / Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function by Garcia (1999)
10.2174/156652408783769571 / Curr. Mol. Med. / Ca(2+) signaling, mitochondria and cell death by Giorgi (2008)
10.1038/nri1527 / Nat. Rev., Immunol. / The neuropathogenesis of AIDS by González-Scarano (2005)
10.1084/jem.191.1.33 / J. Exp. Med. / The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore by Jacotot (2000)
10.1186/1742-4690-4-84 / Retrovirology / Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages by Jacquot (2007)
10.1016/0304-3940(94)11792-H / Neurosci. Lett. / Establishment of human microglial cell lines after transfection of primary cultures of embryonic microglial cells with the SV40 large T antigen by Janabi (1995)
10.1523/JNEUROSCI.5522-06.2007 / J. Neurosci. / HIV-1 Vpr causes neuronal apoptosis and in vivo neurodegeneration by Jones (2007)
10.2741/2860 / Front. Biosci. / HIV's double strike at the brain: neuronal toxicity and compromised neurogenesis by Kaul (2008)
10.1128/JVI.02094-07 / J. Virol. / Human immunodeficiency virus type 1 Vpr inhibits axonal outgrowth through induction of mitochondrial dysfunction by Kitayama (2008)
10.1074/jbc.M710298200 / J. Biol. Chem. / Assembly with the Cul4A-DDB1 DCAF1 ubiquitin ligase protects HIV-1 Vpr from proteasomal degradation by Le Rouzic (2008)
10.1523/JNEUROSCI.21-13-04572.2001 / J. Neurosci. / Kainate receptors expressed by a subpopulation of developing nociceptors rapidly switch from high to low Ca2+ permeability by Lee (2001)
10.1523/JNEUROSCI.4677-07.2008 / J. Neurosci. / The mitochondrial protease AFG3L2 is essential for axonal development by Maltecca (2008)
10.1038/ncb1203-1041 / Nat. Cell Biol. / Calcium orchestrates apoptosis by Mattson (2003)
{'key': '10.1016/j.brainres.2009.03.024_bib27', 'first-page': 'G1007', 'article-title': 'Acidosis induces hyperpermeability in Caco-2BBe cultured intestinal epithelial monolayers', 'volume': '272', 'author': 'Menconi', 'year': '1997', 'journal-title': 'Am. J. Physiol.'} / Am. J. Physiol. / Acidosis induces hyperpermeability in Caco-2BBe cultured intestinal epithelial monolayers by Menconi (1997)
10.1128/JVI.01928-06 / J. Virol. / Novel nuclear import of Vpr promoted by importin alpha is crucial for human immunodeficiency virus type 1 replication in macrophages by Nitahara-Kasahara (2007)
10.1242/jcs.03462 / J. Cell. Sci. / New molecular players in capacitative Ca2+ entry by Putney (2007)
10.1111/j.1747-0285.2006.00340.x / Chem. Biol. Drug Des. / Interaction between the HIV-1 protein Vpr and the adenine nucleotide translocator by Sabbah (2006)
10.1002/(SICI)1097-4547(20000301)59:5<671::AID-JNR10>3.0.CO;2-B / J. Neurosci. Res. / Fibroblast growth factor modulates HIV coreceptor CXCR4 expression by neural cells by Sanders (2000)
10.1007/s10495-005-2467-x / Apoptosis / p73 modulates HIV-1 Tat transcriptional and apoptotic activities in human astrocytes by Saunders (2005)
10.1074/jbc.M005197200 / J. Biol. Chem. / Cooperative interaction between HIV-1 regulatory proteins Tat and Vpr modulates transcription of the viral genome by Sawaya (2000)
10.1038/sj.onc.1210632 / Oncogene / Molecular mimicry in inducing DNA damage between HIV-1 Vpr and the anticancer agent, cisplatin by Siddiqui (2008)
10.1016/S0143416002001896 / Cell Calcium / The endoplasmic reticulum and neuronal calcium signalling by Verkhratsky (2002)

Dates

Type	When
Created	16 years, 5 months ago (March 26, 2009, 5:09 a.m.)
Deposited	6 years, 3 months ago (May 18, 2019, 11 p.m.)
Indexed	1 month ago (Aug. 2, 2025, 12:49 a.m.)
Issued	16 years, 3 months ago (June 1, 2009)
Published	16 years, 3 months ago (June 1, 2009)
Published Print	16 years, 3 months ago (June 1, 2009)

Funders 0

None

BibTeX

@article{Rom_2009, title={HIV-1 Vpr deregulates calcium secretion in neural cells}, volume={1275}, ISSN={0006-8993}, url={http://dx.doi.org/10.1016/j.brainres.2009.03.024}, DOI={10.1016/j.brainres.2009.03.024}, journal={Brain Research}, publisher={Elsevier BV}, author={Rom, Inna and Deshmane, Satish L. and Mukerjee, Ruma and Khalili, Kamel and Amini, Shohreh and Sawaya, Bassel E.}, year={2009}, month=jun, pages={81–86} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        2
      ]
    ],
    "date-time": "2025-08-02T04:49:15Z",
    "timestamp": 1754110155316
  },
  "reference-count": 35,
  "publisher": "Elsevier BV",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2009,
            6,
            1
          ]
        ],
        "date-time": "2009-06-01T00:00:00Z",
        "timestamp": 1243814400000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2009,
        6
      ]
    ]
  },
  "DOI": "10.1016/j.brainres.2009.03.024",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2009,
        3,
        26
      ]
    ],
    "date-time": "2009-03-26T09:09:22Z",
    "timestamp": 1238058562000
  },
  "page": "81-86",
  "source": "Crossref",
  "is-referenced-by-count": 36,
  "special_numbering": "C",
  "title": "HIV-1 Vpr deregulates calcium secretion in neural cells",
  "prefix": "10.1016",
  "volume": "1275",
  "author": [
    {
      "given": "Inna",
      "family": "Rom",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Satish L.",
      "family": "Deshmane",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Ruma",
      "family": "Mukerjee",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Kamel",
      "family": "Khalili",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Shohreh",
      "family": "Amini",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Bassel E.",
      "family": "Sawaya",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/j.brainres.2009.03.024_bib1",
      "doi-asserted-by": "crossref",
      "first-page": "46046",
      "DOI": "10.1074/jbc.M403792200",
      "article-title": "Interplay between HIV-1 Vpr and Sp1 modulates p21WAF1 gene expression in human astrocytes",
      "volume": "279",
      "author": "Amini",
      "year": "2004",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib2",
      "doi-asserted-by": "crossref",
      "first-page": "8126",
      "DOI": "10.1128/MCB.25.18.8126-8138.2005",
      "article-title": "p73 interacts with HIV-1 Tat in astrocytic cells and prevents its acetylation on Lys28",
      "volume": "25",
      "author": "Amini",
      "year": "2005",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib3",
      "doi-asserted-by": "crossref",
      "first-page": "751",
      "DOI": "10.1038/351751a0",
      "article-title": "Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum",
      "volume": "351",
      "author": "Bezprozvanny",
      "year": "1991",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib4",
      "doi-asserted-by": "crossref",
      "first-page": "356",
      "DOI": "10.1111/j.1749-6632.2002.tb04762.x",
      "article-title": "Na/Ca exchanger and PMCA localization in neurons and astrocytes: functional implications",
      "volume": "976",
      "author": "Blaustein",
      "year": "2002",
      "journal-title": "Ann. N.Y. Acad. Sci."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib5",
      "doi-asserted-by": "crossref",
      "first-page": "252",
      "DOI": "10.4161/cc.3.3.705",
      "article-title": "Apoptosis and calcium: new roles for cytochrome c and inositol 1,4,5-trisphosphate",
      "volume": "3",
      "author": "Boehning",
      "year": "2004",
      "journal-title": "Cell Cycle"
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib6",
      "doi-asserted-by": "crossref",
      "first-page": "1466",
      "DOI": "10.1073/pnas.0409650102",
      "article-title": "A peptide inhibitor of cytochrome c/inositol 1,4,5-trisphosphate receptor binding blocks intrinsic and extrinsic cell death pathways",
      "volume": "102",
      "author": "Boehning",
      "year": "2005",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "15923",
      "DOI": "10.1074/jbc.M602249200",
      "article-title": "Messenger-specific role for nicotinic acid adenine dinucleotide phosphate in neuronal differentiation",
      "volume": "281",
      "author": "Brailoiu",
      "year": "2006",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib8",
      "doi-asserted-by": "crossref",
      "first-page": "C817",
      "DOI": "10.1152/ajpcell.00139.2004",
      "article-title": "Calcium, ATP, and ROS: a mitochondrial love-hate triangle",
      "volume": "287",
      "author": "Brookes",
      "year": "2004",
      "journal-title": "Am. J. Physiol., Cell Physiol."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "727",
      "DOI": "10.1016/j.neuroscience.2006.01.034",
      "article-title": "Differences in mitochondrial movement and morphology in young and mature primary cortical neurons in culture",
      "volume": "141",
      "author": "Chang",
      "year": "2006",
      "journal-title": "Neuroscience"
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "2436",
      "DOI": "10.1007/s11064-008-9694-9",
      "article-title": "Metabotropic glutamate receptors in glial cells",
      "volume": "33",
      "author": "D'Antoni",
      "year": "2008",
      "journal-title": "Neurochem. Res."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib11",
      "doi-asserted-by": "crossref",
      "first-page": "405",
      "DOI": "10.1146/annurev.pathol.1.110304.100218",
      "article-title": "Calcium in cell injury and death",
      "volume": "1",
      "author": "Dong",
      "year": "2006",
      "journal-title": "Annu. Rev. Pathol."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "493",
      "DOI": "10.1006/mcne.2002.1196",
      "article-title": "Lithium ameliorates HIV-gp120-mediated neurotoxicity",
      "volume": "21",
      "author": "Everall",
      "year": "2002",
      "journal-title": "Mol. Cell. Neurosci."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "893",
      "DOI": "10.1152/physrev.00013.2002",
      "article-title": "Ryanodine receptor calcium release channels",
      "volume": "82",
      "author": "Fill",
      "year": "2002",
      "journal-title": "Physiol. Rev."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib14",
      "doi-asserted-by": "crossref",
      "first-page": "D869",
      "DOI": "10.2741/Garcia",
      "article-title": "Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function",
      "volume": "4",
      "author": "Garcia",
      "year": "1999",
      "journal-title": "Front. Biosci."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "119",
      "DOI": "10.2174/156652408783769571",
      "article-title": "Ca(2+) signaling, mitochondria and cell death",
      "volume": "8",
      "author": "Giorgi",
      "year": "2008",
      "journal-title": "Curr. Mol. Med."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib16",
      "doi-asserted-by": "crossref",
      "first-page": "69",
      "DOI": "10.1038/nri1527",
      "article-title": "The neuropathogenesis of AIDS",
      "volume": "5",
      "author": "Gonz\u00e1lez-Scarano",
      "year": "2005",
      "journal-title": "Nat. Rev., Immunol."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib17",
      "doi-asserted-by": "crossref",
      "first-page": "33",
      "DOI": "10.1084/jem.191.1.33",
      "article-title": "The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore",
      "volume": "191",
      "author": "Jacotot",
      "year": "2000",
      "journal-title": "J. Exp. Med."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib18",
      "doi-asserted-by": "crossref",
      "first-page": "84",
      "DOI": "10.1186/1742-4690-4-84",
      "article-title": "Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages",
      "volume": "4",
      "author": "Jacquot",
      "year": "2007",
      "journal-title": "Retrovirology"
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "105",
      "DOI": "10.1016/0304-3940(94)11792-H",
      "article-title": "Establishment of human microglial cell lines after transfection of primary cultures of embryonic microglial cells with the SV40 large T antigen",
      "volume": "195",
      "author": "Janabi",
      "year": "1995",
      "journal-title": "Neurosci. Lett."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "3703",
      "DOI": "10.1523/JNEUROSCI.5522-06.2007",
      "article-title": "HIV-1 Vpr causes neuronal apoptosis and in vivo neurodegeneration",
      "volume": "27",
      "author": "Jones",
      "year": "2007",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "2484",
      "DOI": "10.2741/2860",
      "article-title": "HIV's double strike at the brain: neuronal toxicity and compromised neurogenesis",
      "volume": "13",
      "author": "Kaul",
      "year": "2008",
      "journal-title": "Front. Biosci."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "2528",
      "DOI": "10.1128/JVI.02094-07",
      "article-title": "Human immunodeficiency virus type 1 Vpr inhibits axonal outgrowth through induction of mitochondrial dysfunction",
      "volume": "82",
      "author": "Kitayama",
      "year": "2008",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "21686",
      "DOI": "10.1074/jbc.M710298200",
      "article-title": "Assembly with the Cul4A-DDB1 DCAF1 ubiquitin ligase protects HIV-1 Vpr from proteasomal degradation",
      "volume": "283",
      "author": "Le Rouzic",
      "year": "2008",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib24",
      "doi-asserted-by": "crossref",
      "first-page": "4572",
      "DOI": "10.1523/JNEUROSCI.21-13-04572.2001",
      "article-title": "Kainate receptors expressed by a subpopulation of developing nociceptors rapidly switch from high to low Ca2+ permeability",
      "volume": "21",
      "author": "Lee",
      "year": "2001",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "2827",
      "DOI": "10.1523/JNEUROSCI.4677-07.2008",
      "article-title": "The mitochondrial protease AFG3L2 is essential for axonal development",
      "volume": "28",
      "author": "Maltecca",
      "year": "2008",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "1041",
      "DOI": "10.1038/ncb1203-1041",
      "article-title": "Calcium orchestrates apoptosis",
      "volume": "5",
      "author": "Mattson",
      "year": "2003",
      "journal-title": "Nat. Cell Biol."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib27",
      "first-page": "G1007",
      "article-title": "Acidosis induces hyperpermeability in Caco-2BBe cultured intestinal epithelial monolayers",
      "volume": "272",
      "author": "Menconi",
      "year": "1997",
      "journal-title": "Am. J. Physiol."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "5284",
      "DOI": "10.1128/JVI.01928-06",
      "article-title": "Novel nuclear import of Vpr promoted by importin alpha is crucial for human immunodeficiency virus type 1 replication in macrophages",
      "volume": "81",
      "author": "Nitahara-Kasahara",
      "year": "2007",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib29",
      "doi-asserted-by": "crossref",
      "first-page": "1959",
      "DOI": "10.1242/jcs.03462",
      "article-title": "New molecular players in capacitative Ca2+ entry",
      "volume": "120",
      "author": "Putney",
      "year": "2007",
      "journal-title": "J. Cell. Sci."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "145",
      "DOI": "10.1111/j.1747-0285.2006.00340.x",
      "article-title": "Interaction between the HIV-1 protein Vpr and the adenine nucleotide translocator",
      "volume": "67",
      "author": "Sabbah",
      "year": "2006",
      "journal-title": "Chem. Biol. Drug Des."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib31",
      "doi-asserted-by": "crossref",
      "first-page": "671",
      "DOI": "10.1002/(SICI)1097-4547(20000301)59:5<671::AID-JNR10>3.0.CO;2-B",
      "article-title": "Fibroblast growth factor modulates HIV coreceptor CXCR4 expression by neural cells",
      "volume": "59",
      "author": "Sanders",
      "year": "2000",
      "journal-title": "J. Neurosci. Res."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "1419",
      "DOI": "10.1007/s10495-005-2467-x",
      "article-title": "p73 modulates HIV-1 Tat transcriptional and apoptotic activities in human astrocytes",
      "volume": "10",
      "author": "Saunders",
      "year": "2005",
      "journal-title": "Apoptosis"
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "35209",
      "DOI": "10.1074/jbc.M005197200",
      "article-title": "Cooperative interaction between HIV-1 regulatory proteins Tat and Vpr modulates transcription of the viral genome",
      "volume": "275",
      "author": "Sawaya",
      "year": "2000",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "32",
      "DOI": "10.1038/sj.onc.1210632",
      "article-title": "Molecular mimicry in inducing DNA damage between HIV-1 Vpr and the anticancer agent, cisplatin",
      "volume": "27",
      "author": "Siddiqui",
      "year": "2008",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1016/j.brainres.2009.03.024_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "393",
      "DOI": "10.1016/S0143416002001896",
      "article-title": "The endoplasmic reticulum and neuronal calcium signalling",
      "volume": "32",
      "author": "Verkhratsky",
      "year": "2002",
      "journal-title": "Cell Calcium"
    }
  ],
  "container-title": "Brain Research",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0006899309005277?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0006899309005277?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2019,
        5,
        19
      ]
    ],
    "date-time": "2019-05-19T03:00:41Z",
    "timestamp": 1558234841000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0006899309005277"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2009,
        6
      ]
    ]
  },
  "references-count": 35,
  "alternative-id": [
    "S0006899309005277"
  ],
  "URL": "http://dx.doi.org/10.1016/j.brainres.2009.03.024",
  "relation": {},
  "ISSN": [
    "0006-8993"
  ],
  "subject": [],
  "container-title-short": "Brain Research",
  "published": {
    "date-parts": [
      [
        2009,
        6
      ]
    ]
  }
}