Bibliography
Miao, H.-Q., Hu, K., Jimenez, X., Navarro, E., Zhang, H., Lu, D., Ludwig, D. L., Balderes, P., & Zhu, Z. (2006). Potent neutralization of VEGF biological activities with a fully human antibody Fab fragment directed against VEGF receptor 2. Biochemical and Biophysical Research Communications, 345(1), 438â445.
References
48
Referenced
67
10.1038/nature04483
/ Nature / Angiogenesis as a therapeutic target by Ferrara (2005)10.1038/nature04478
/ Nature / Angiogenesis in life, disease and medicine by Carmeliet (2005)10.1016/S1350-9462(02)00043-5
/ Prog. Retin. Eye Res. / Vascular endothelial growth factors and angiogenesis in eye disease by Witmer (2003){'key': '10.1016/j.bbrc.2006.04.119_bib4', 'first-page': '209', 'article-title': 'The role of VEGF in the regulation of physiological and pathological angiogenesis', 'author': 'Ferrara', 'year': '2005', 'journal-title': 'Exs'}
/ Exs / The role of VEGF in the regulation of physiological and pathological angiogenesis by Ferrara (2005)10.1247/csf.26.25
/ Cell Struct. Funct. / Structure and function of VEGF/VEGF-receptor system involved in angiogenesis by Shibuya (2001)10.1006/scbi.1998.0091
/ Semin. Cancer Biol. / VEGFs, receptors and angiogenesis by Veikkola (1999)10.1038/362841a0
/ Nature / Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo by Kim (1993)10.1038/nrd1381
/ Nat. Rev. Drug Discov. / Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer by Ferrara (2004){'key': '10.1016/j.bbrc.2006.04.119_bib9', 'first-page': '5209', 'article-title': 'Anti-vascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors', 'volume': '59', 'author': 'Prewett', 'year': '1999', 'journal-title': 'Cancer Res.'}
/ Cancer Res. / Anti-vascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors by Prewett (1999)10.1038/sj.leu.2402831
/ Leukemia / Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity by Zhu (2003)10.1073/pnas.0509069102
/ Proc. Natl. Acad. Sci. USA / A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165 by Lee (2005){'key': '10.1016/j.bbrc.2006.04.119_bib12', 'first-page': '1324', 'article-title': 'Vascular endothelial growth factor-toxin conjugate specifically inhibits KDR/flk-1-positive endothelial cell proliferation in vitro and angiogenesis in vivo', 'volume': '56', 'author': 'Ramakrishnan', 'year': '1996', 'journal-title': 'Cancer Res.'}
/ Cancer Res. / Vascular endothelial growth factor-toxin conjugate specifically inhibits KDR/flk-1-positive endothelial cell proliferation in vitro and angiogenesis in vivo by Ramakrishnan (1996)10.1007/s11912-001-0014-7
/ Curr. Oncol. Rep. / Angiozyme: a novel angiogenesis inhibitor by Weng (2001){'key': '10.1016/j.bbrc.2006.04.119_bib14', 'first-page': '493', 'article-title': 'Technology evaluation: VEGF Trap (cancer), Regeneron/sanofi-aventis', 'volume': '7', 'author': 'Lau', 'year': '2005', 'journal-title': 'Curr. Opin. Mol. Ther.'}
/ Curr. Opin. Mol. Ther. / Technology evaluation: VEGF Trap (cancer), Regeneron/sanofi-aventis by Lau (2005)10.2174/0929867043455756
/ Curr. Med. Chem. / Development of vascular endothelial growth factor receptor (VEGFR) kinase inhibitors as anti-angiogenic agents in cancer therapy by Underiner (2004)10.1159/000088479
/ Oncology / VEGF as a therapeutic target in cancer by Ferrara (2005)10.2741/1629
/ Front. Biosci. / Development of angiogenesis inhibitors to vascular endothelial growth factor receptor 2. Current status and future perspective by Paz (2005)10.2174/1568009023333881
/ Curr. Cancer Drug Targets / Clinical development of angiogenesis inhibitors to vascular endothelial growth factor and its receptors as cancer therapeutics by Zhu (2002){'key': '10.1016/j.bbrc.2006.04.119_bib19', 'first-page': '3209', 'article-title': 'Inhibition of vascular endothelial growth factor-induced receptor activation with anti-kinase insert domain-containing receptor single-chain antibodies from a phage display library', 'volume': '58', 'author': 'Zhu', 'year': '1998', 'journal-title': 'Cancer Res.'}
/ Cancer Res. / Inhibition of vascular endothelial growth factor-induced receptor activation with anti-kinase insert domain-containing receptor single-chain antibodies from a phage display library by Zhu (1998)10.1016/S0304-3835(98)00324-3
/ Cancer Lett. / Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody by Zhu (1999){'key': '10.1016/j.bbrc.2006.04.119_bib21', 'first-page': '474', 'article-title': 'Localization of VEGF receptor-2 (KDR/Flk-1) and effects of blocking it in oxygen-induced retinopathy', 'volume': '43', 'author': 'McLeod', 'year': '2002', 'journal-title': 'Invest. Ophthalmol. Vis. Sci.'}
/ Invest. Ophthalmol. Vis. Sci. / Localization of VEGF receptor-2 (KDR/Flk-1) and effects of blocking it in oxygen-induced retinopathy by McLeod (2002)10.1002/ijc.1634
/ Int. J. Cancer / Selection of high affinity human neutralizing antibodies to VEGFR2 from a large antibody phage display library for anti-angiogenesis therapy by Lu (2002)10.1074/jbc.M307742200
/ J. Biol. Chem. / Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity by Lu (2003)10.1074/jbc.275.19.14321
/ J. Biol. Chem. / Identification of the residues in the extracellular region of KDR important for interaction with vascular endothelial growth factor and neutralizing anti-KDR antibodies by Lu (2000)10.1242/jcs.01138
/ J. Cell Sci. / Involvement of the VEGF receptor 3 in tubular morphogenesis demonstrated with a human anti-human VEGFR-3 monoclonal antibody that antagonizes receptor activation by VEGF-C by Persaud (2004)10.1023/A:1006094117427
/ Cancer Metastasis Rev. / Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy by Witte (1998)10.1016/S0021-9258(18)47116-5
/ J. Biol. Chem. / Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor by Waltenberger (1994)10.1074/jbc.270.12.6729
/ J. Biol. Chem. / Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation by Guo (1995)10.1074/jbc.273.46.30336
/ J. Biol. Chem. / Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation by Gerber (1998)10.1038/sj.onc.1201047
/ Oncogene / The 230kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-γ pathway and partially induces mitotic signals in NIH3T3 fibroblasts by Takahashi (1997)10.1042/bj3530503
/ Biochem. J. / Vascular endothelial growth factor-induced prostacyclin production is mediated by a protein kinase C (PKC)-dependent activation of extracellular signal-regulated protein kinases 1 and 2 involving PKC-δ and by mobilization of intracellular Ca2+ by Gliki (2001)10.1038/sj.onc.1202527
/ Oncogene / VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells by Takahashi (1999)10.1073/pnas.90.16.7533
/ Proc. Natl. Acad. Sci. USA / Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium by Quinn (1993){'key': '10.1016/j.bbrc.2006.04.119_bib34', 'first-page': 'H586', 'article-title': 'Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries', 'volume': '265', 'author': 'Ku', 'year': '1993', 'journal-title': 'Am. J. Physiol.'}
/ Am. J. Physiol. / Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries by Ku (1993){'key': '10.1016/j.bbrc.2006.04.119_bib35', 'first-page': 'H687', 'article-title': 'Vascular endothelial growth factor increases microvascular permeability via a Ca(2+)-dependent pathway', 'volume': '273', 'author': 'Bates', 'year': '1997', 'journal-title': 'Am. J. Physiol.'}
/ Am. J. Physiol. / Vascular endothelial growth factor increases microvascular permeability via a Ca(2+)-dependent pathway by Bates (1997)10.1152/ajpcell.2001.281.5.C1448
/ Am. J. Physiol. Cell Physiol. / Role of PLCgamma and Ca(2+) in VEGF- and FGF-induced choroidal endothelial cell proliferation by McLaughlin (2001)10.1152/ajpcell.1999.276.1.C176
/ Am. J. Physiol. / KDR activation is crucial for VEGF165-mediated Ca2+ mobilization in human umbilical vein endothelial cells by Cunningham (1999)10.1074/jbc.M103130200
/ J. Biol. Chem. / Tyrosine residues 951 and 1059 of vascular endothelial growth factor receptor-2 (KDR) are essential for vascular permeability factor/vascular endothelial growth factor-induced endothelium migration and proliferation, respectively by Zeng (2001)10.1016/S1359-6446(01)01759-7
/ Drug Discov. Today / Monoclonal antibody strategies to block angiogenesis by Hicklin (2001)10.1172/JCI200318740
/ J. Clin. Invest. / Vascular endothelial growth factor receptor 2-mediated angiogenesis is essential for gonadotropin-dependent follicle development by Zimmermann (2003)10.1210/endo.143.7.8896
/ Endocrinology / Administration of anti-vascular endothelial growth factor receptor 2 antibody in the early follicular phase delays follicular selection and development in the rhesus monkey by Zimmermann (2002)10.1053/j.seminoncol.2004.09.026
/ Semin. Oncol. / Targeting vascular endothelial growth factor and angiogenesis for the treatment of colorectal cancer by Collins (2005)10.1097/00004397-200404430-00005
/ Int. Ophthalmol. Clin. / Anti-vascular endothelial growth factor strategies for the treatment of choroidal neovascularization from age-related macular degeneration by Barouch (2004){'key': '10.1016/j.bbrc.2006.04.119_bib44', 'first-page': '366', 'article-title': 'Inhibition of retinal and choroidal neovascularization by a novel KDR kinase inhibitor', 'volume': '11', 'author': 'Kinose', 'year': '2005', 'journal-title': 'Mol. Vis.'}
/ Mol. Vis. / Inhibition of retinal and choroidal neovascularization by a novel KDR kinase inhibitor by Kinose (2005)10.1001/archopht.120.3.338
/ Arch. Ophthalmol. / Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment by Krzystolik (2002)10.1016/j.ophtha.2005.01.043
/ Ophthalmology / Maximum tolerated dose of a humanized anti-vascular endothelial growth factor antibody fragment for treating neovascular age-related macular degeneration by Rosenfeld (2005)10.1517/14656566.6.8.1421
/ Expert Opin. Pharmacother. / Pegaptanib: the first anti-angiogenic agent approved for neovascular macular degeneration by Doggrell (2005)10.1056/NEJMoa042760
/ N. Engl. J. Med. / Pegaptanib for neovascular age-related macular degeneration by Gragoudas (2004)
Dates
Type | When |
---|---|
Created | 19 years, 3 months ago (May 5, 2006, 1:51 a.m.) |
Deposited | 4 years, 1 month ago (July 26, 2021, 1:11 p.m.) |
Indexed | 11 months, 2 weeks ago (Sept. 16, 2024, 9:15 a.m.) |
Issued | 19 years, 3 months ago (June 1, 2006) |
Published | 19 years, 3 months ago (June 1, 2006) |
Published Print | 19 years, 3 months ago (June 1, 2006) |
@article{Miao_2006, title={Potent neutralization of VEGF biological activities with a fully human antibody Fab fragment directed against VEGF receptor 2}, volume={345}, ISSN={0006-291X}, url={http://dx.doi.org/10.1016/j.bbrc.2006.04.119}, DOI={10.1016/j.bbrc.2006.04.119}, number={1}, journal={Biochemical and Biophysical Research Communications}, publisher={Elsevier BV}, author={Miao, Hua-Quan and Hu, Kun and Jimenez, Xenia and Navarro, Elizabeth and Zhang, Haifan and Lu, Dan and Ludwig, Dale L. and Balderes, Paul and Zhu, Zhenping}, year={2006}, month=jun, pages={438–445} }