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journal-article
Elsevier BV
Biochemical and Biophysical Research Communications (78)
References
76
Referenced
134
10.1007/BF01535205
/ Somat. Cell Mol. Genet. / Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line by Cahilly-Snyder (1987)10.1016/0092-8674(92)90644-R
/ Cell / The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation by Momand (1992)10.1038/358080a0
/ Nature / Amplification of a gene encoding a p53-associated protein in human sarcomas by Oliner (1992)10.1038/387296a0
/ Nature / Mdm2 promotes the rapid degradation of p53 by Haupt (1997)10.1038/387299a0
/ Nature / Regulation of p53 stability by Mdm2 by Kubbutat (1997)10.1016/S0014-5793(97)01480-4
/ FEBS Lett. / Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53 by Honda (1997)10.1038/378203a0
/ Nature / Rescue of early embryonic lethality in mdm2-deficient mice by absence of p53 by Montes de Oca Luna (1995)10.1038/378206a0
/ Nature / Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53 by Jones (1995)10.1016/S0960-9822(02)01319-2
/ Curr. Biol. / Zebrafish as a model organism for the identification and characterization of drugs and genes affecting p53 signaling by Langheinrich (2002)10.1128/MCB.23.2.462-473.2003
/ Mol. Cell. Biol. / mdm2 is critical for inhibition of p53 during lymphopoiesis and the response to ionizing irradiation by Mendrysa (2003)10.1002/j.1460-2075.1996.tb00919.x
/ EMBO J. / MDMX: a novel p53-binding protein with some functional properties of MDM2 by Shvarts (1996)10.1006/geno.1997.4775
/ Genomics / Isolation and identification of the human homolog of a new p53-binding protein, Mdmx by Shvarts (1997)10.1074/jbc.274.53.38189
/ J. Biol. Chem. / Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein by Sharp (1999)10.1016/S0014-5793(99)00254-9
/ FEBS Lett. / MDM2 interacts with MDMX through their RING finger domains by Tanimura (1999)10.1007/BF03401678
/ Mol. Med. / A genetic approach to mapping the p53 binding site in the MDM2 protein by Freedman (1997)10.1074/jbc.M010685200
/ J. Biol. Chem. / MdmX binding to ARF affects Mdm2 protein stability and p53 transactivation by Jackson (2001)10.1128/MCB.20.7.2517-2528.2000
/ Mol. Cell. Biol. / Cooperative signals governing ARF–mdm2 interaction and nucleolar localization of the complex by Weber (2000)10.1038/35004057
/ Nat. Cell Biol. / Identification of a cryptic nucleolar-localization signal in MDM2 by Lohrum (2000)10.1016/S0014-5793(04)00168-1
/ FEBS Lett. / Inhibition of p53 degradation by Mdm2 acetylation by Wang (2004)10.1016/0378-1119(96)00151-5
/ Gene / Genomic organization of the mouse double minute 2 gene by Jones (1996)10.1006/geno.1996.0210
/ Genomics / The organization and expression of the mdm2 gene by Montes de Oca Luna (1996)10.1016/S0378-1119(01)00432-2
/ Gene / Organization, expression, and localization of the murine mdmx gene and pseudogene by Parant (2001)10.1101/gad.7.7a.1126
/ Genes Dev. / The p53–mdm-2 autoregulatory feedback loop by Wu (1993)10.1002/j.1460-2075.1993.tb05678.x
/ EMBO J. / mdm2 expression is induced by wild type p53 activity by Barak (1993){'key': '10.1016/j.bbrc.2005.03.151_bib25', 'first-page': '993', 'article-title': 'MDM2, an introduction', 'volume': '1', 'author': 'Iwakuma', 'year': '2003', 'journal-title': 'Mol. Cancer Res.'}
/ Mol. Cancer Res. / MDM2, an introduction by Iwakuma (2003){'key': '10.1016/j.bbrc.2005.03.151_bib26', 'first-page': '1839', 'article-title': 'Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53', 'volume': '61', 'author': 'Ramos', 'year': '2001', 'journal-title': 'Cancer Res.'}
/ Cancer Res. / Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53 by Ramos (2001)10.1074/jbc.274.12.8299
/ J. Biol. Chem. / A novel MDMX transcript expressed in a variety of transformed cell lines encodes a truncated protein with potent p53 repressive activity by Rallapalli (1999)10.1038/ng714
/ Nat. Genet. / Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53 by Parant (2001)10.1128/MCB.22.15.5527-5538.2002
/ Mol. Cell. Biol. / Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development by Migliorini (2002){'key': '10.1016/j.bbrc.2005.03.151_bib30', 'first-page': '3221', 'article-title': 'Mdmx is a negative regulator of p53 activity in vivo', 'volume': '62', 'author': 'Finch', 'year': '2002', 'journal-title': 'Cancer Res.'}
/ Cancer Res. / Mdmx is a negative regulator of p53 activity in vivo by Finch (2002)10.4161/cc.3.7.998
/ Cell Cycle / Mdmx and Mdm2: brothers in arms? by Marine (2004)10.1038/sj.onc.1208256
/ Oncogene / Dapk1, encoding an activator of a p19ARF-p53 mediated apoptotic checkpoint, is a transcription target of p53 by Martoriati (2005)10.1038/sj.onc.1202281
/ Oncogene / Comparative study of the p53–mdm2 and p53–DMX interfaces by Bottger (1999)10.1089/104454902320219077
/ DNA Cell Biol. / MDMX inhibits the p300/CBP-mediated acetylation of p53 by Sabbatini (2002)10.1128/MCB.24.13.5835-5843.2004
/ Mol. Cell. Biol. / Amplification of Mdmx (or Mdm4) directly contributes to tumour formation by inhibiting p53-tumour suppressor activity by Danovi (2004)10.1016/S0092-8674(01)00619-5
/ Cell / Why is p53 acetylated? by Prives (2001)10.1128/MCB.20.3.1001-1007.2000
/ Mol. Cell. Biol. / MdmX protects p53 from Mdm2-mediated degradation by Jackson (2000)10.1074/jbc.M003496200
/ J. Biol. Chem. / Hdmx stabilizes Mdm2 and p53 by Stad (2000)10.1093/embo-reports/kve227
/ EMBO Rep. / Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms by Stad (2001)10.1074/jbc.M108795200
/ J. Biol. Chem. / Hdmx recruitment into the nucleus by Hdm2 is essential for its ability to regulate p53 stability and transactivation by Migliorini (2002)10.1128/MCB.23.14.4929-4938.2003
/ Mol. Cell. Biol. / Critical role for a central part of Mdm2 in the ubiquitylation of p53 by Meulmeester (2003)10.1128/MCB.23.14.4939-4947.2003
/ Mol. Cell. Biol. / Critical contribution of the MDM2 acidic domain to p53 ubiquitination by Kawai (2003)10.1038/35023500
/ Nat. Cell Biol. / An intact HDM2 RING-finger domain is required for nuclear exclusion of p53 by Boyd (2000)10.1038/35023507
/ Nat. Cell Biol. / The MDM2 RING-finger domain is required to promote p53 nuclear export by Geyer (2000)10.1074/jbc.C200150200
/ J. Biol. Chem. / Mutual dependence of MDM2 and MDMX in their functional inactivation of p53 by Gu (2002)10.1073/pnas.2030930100
/ Proc. Natl. Acad. Sci. USA / HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53 by Linares (2003)10.1093/emboj/17.2.554
/ EMBO J. / Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein by Roth (1998)10.1128/MCB.22.21.7562-7571.2002
/ Mol. Cell. Biol. / DNA damage induces MDMX nuclear translocation by p53-dependent and -independent mechanisms by Li (2002)10.1074/jbc.M213034200
/ J. Biol. Chem. / Hdmx protein stability is regulated by the ubiquitin ligase activity of Mdm2 by de Graaf (2003)10.1128/MCB.23.15.5113-5121.2003
/ Mol. Cell. Biol. / MDM2 promotes ubiquitination and degradation of MDMX by Pan (2003)10.1074/jbc.M308295200
/ J. Biol. Chem. / DNA damage-induced MDMX degradation is mediated by MDM2 by Kawai (2003)10.1073/pnas.0408595102
/ Proc. Natl. Acad. Sci. USA / Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage by Pereg (2005)10.1074/jbc.274.12.8161
/ J. Biol. Chem. / Multiple murine double minute gene 2 (MDM2) proteins are induced by ultraviolet light by Saucedo (1999)10.1074/jbc.275.8.5733
/ J. Biol. Chem. / p76(MDM2) inhibits the ability of p90(MDM2) to destabilize p53 by Perry (2000)10.1038/sj.onc.1205137
/ Oncogene / MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts by Gentiletti (2002)10.1074/jbc.M311793200
/ J. Biol. Chem. / MDM4 (MDMX) overexpression enhances stabilization of stress-induced p53 and promotes apoptosis by Mancini (2004){'key': '10.1016/j.bbrc.2005.03.151_bib56', 'first-page': '6091', 'article-title': 'Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification', 'volume': '59', 'author': 'Riemenschneider', 'year': '1999', 'journal-title': 'Cancer Res.'}
/ Cancer Res. / Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification by Riemenschneider (1999)10.1002/ijc.11023
/ Int. J. Cancer / Refined mapping of 1q32 amplicons in malignant gliomas confirms MDM4 as the main amplification target by Riemenschneider (2003)10.1126/science.1092472
/ Science / In vivo activation of the p53 pathway by small-molecule antagonists of MDM2 by Vassilev (2004)10.1158/1541-7786.29.2.1
/ Mol. Cancer Res. / MDM2 and its splice variant messenger RNAs: expression in tumors and down-regulation using antisense oligonucleotides by Bartel (2004)10.1002/jcb.10535
/ J. Cell. Biochem. / Identification of a domain within MDMX-S that is responsible for its high affinity interaction with p53 and high-level expression in mammalian cells by Rallapalli (2003)10.1038/nature737
/ Nature / Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization by Li (2002)10.1016/S1097-2765(04)00157-1
/ Mol. Cell / A dynamic role of HAUSP in the p53–Mdm2 pathway by Li (2004)10.1038/nature02501
/ Nature / Tumour suppression: disruption of HAUSP gene stabilizes p53 by Cummins (2004){'key': '10.1016/j.bbrc.2005.03.151_bib64', 'first-page': '1027', 'article-title': 'p53-independent functions of MDM2', 'volume': '1', 'author': 'Ganguli', 'year': '2003', 'journal-title': 'Mol. Cancer Res.'}
/ Mol. Cancer Res. / p53-independent functions of MDM2 by Ganguli (2003)10.1016/S0960-9822(99)80367-4
/ Curr. Biol. / MDM2 and MDMX bind and stabilize the p53-related protein p73 by Ongkeko (1999)10.1016/S0014-5793(01)02124-X
/ FEBS Lett. / MDM2 and MDMX can interact differently with ARF and members of the p53 family by Wang (2001)10.1038/416560a
/ Nature / p63 and p73 are required for p53-dependent apoptosis in response to DNA damage by Flores (2002)10.1016/j.ccr.2004.06.005
/ Cancer Cell / p63 and p73 are not required for the development and p53-dependent apoptosis of T cells by Senoo (2004)10.1038/sj.onc.1204615
/ Oncogene / Hdmx and Mdm2 can repress transcription activation by p53 but not by p63 by Little (2001)10.1089/10445490152122433
/ DNA Cell Biol. / Regulation of p63 function by Mdm2 and MdmX by Kadakia (2001)10.1074/jbc.M010685200
/ J. Biol. Chem. / MdmX binding to ARF affects Mdm2 protein stability and p53 transactivation by Jackson (2001)10.1101/gad.11.6.714
/ Genes Dev. / Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53 by Lundgren (1997)10.1038/sj.onc.1202448
/ Oncogene / MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice by Alkhalaf (1999)10.1126/science.288.5471.1635
/ Science / The genetic program of hematopoietic stem cells by Phillips (2000)10.1073/pnas.95.26.15608
/ Proc. Natl. Acad. Sci. USA / Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis by Jones (1998)
Dates
Type | When |
---|---|
Created | 20 years, 4 months ago (April 8, 2005, 7:44 a.m.) |
Deposited | 1 year, 6 months ago (Jan. 24, 2024, 12:04 p.m.) |
Indexed | 1 month ago (July 22, 2025, 6:33 a.m.) |
Issued | 20 years, 2 months ago (June 1, 2005) |
Published | 20 years, 2 months ago (June 1, 2005) |
Published Print | 20 years, 2 months ago (June 1, 2005) |
@article{Marine_2005, title={Mdmx as an essential regulator of p53 activity}, volume={331}, ISSN={0006-291X}, url={http://dx.doi.org/10.1016/j.bbrc.2005.03.151}, DOI={10.1016/j.bbrc.2005.03.151}, number={3}, journal={Biochemical and Biophysical Research Communications}, publisher={Elsevier BV}, author={Marine, Jean-Christophe and Jochemsen, Aart G.}, year={2005}, month=jun, pages={750–760} }