Crossref journal-article
Elsevier BV
Biochemical and Biophysical Research Communications (78)
Bibliography

Marine, J.-C., & Jochemsen, A. G. (2005). Mdmx as an essential regulator of p53 activity. Biochemical and Biophysical Research Communications, 331(3), 750–760.

Authors 2
  1. Jean-Christophe Marine (first)
  2. Aart G. Jochemsen (additional)
References 76 Referenced 134
  1. 10.1007/BF01535205 / Somat. Cell Mol. Genet. / Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line by Cahilly-Snyder (1987)
  2. 10.1016/0092-8674(92)90644-R / Cell / The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation by Momand (1992)
  3. 10.1038/358080a0 / Nature / Amplification of a gene encoding a p53-associated protein in human sarcomas by Oliner (1992)
  4. 10.1038/387296a0 / Nature / Mdm2 promotes the rapid degradation of p53 by Haupt (1997)
  5. 10.1038/387299a0 / Nature / Regulation of p53 stability by Mdm2 by Kubbutat (1997)
  6. 10.1016/S0014-5793(97)01480-4 / FEBS Lett. / Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53 by Honda (1997)
  7. 10.1038/378203a0 / Nature / Rescue of early embryonic lethality in mdm2-deficient mice by absence of p53 by Montes de Oca Luna (1995)
  8. 10.1038/378206a0 / Nature / Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53 by Jones (1995)
  9. 10.1016/S0960-9822(02)01319-2 / Curr. Biol. / Zebrafish as a model organism for the identification and characterization of drugs and genes affecting p53 signaling by Langheinrich (2002)
  10. 10.1128/MCB.23.2.462-473.2003 / Mol. Cell. Biol. / mdm2 is critical for inhibition of p53 during lymphopoiesis and the response to ionizing irradiation by Mendrysa (2003)
  11. 10.1002/j.1460-2075.1996.tb00919.x / EMBO J. / MDMX: a novel p53-binding protein with some functional properties of MDM2 by Shvarts (1996)
  12. 10.1006/geno.1997.4775 / Genomics / Isolation and identification of the human homolog of a new p53-binding protein, Mdmx by Shvarts (1997)
  13. 10.1074/jbc.274.53.38189 / J. Biol. Chem. / Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein by Sharp (1999)
  14. 10.1016/S0014-5793(99)00254-9 / FEBS Lett. / MDM2 interacts with MDMX through their RING finger domains by Tanimura (1999)
  15. 10.1007/BF03401678 / Mol. Med. / A genetic approach to mapping the p53 binding site in the MDM2 protein by Freedman (1997)
  16. 10.1074/jbc.M010685200 / J. Biol. Chem. / MdmX binding to ARF affects Mdm2 protein stability and p53 transactivation by Jackson (2001)
  17. 10.1128/MCB.20.7.2517-2528.2000 / Mol. Cell. Biol. / Cooperative signals governing ARF–mdm2 interaction and nucleolar localization of the complex by Weber (2000)
  18. 10.1038/35004057 / Nat. Cell Biol. / Identification of a cryptic nucleolar-localization signal in MDM2 by Lohrum (2000)
  19. 10.1016/S0014-5793(04)00168-1 / FEBS Lett. / Inhibition of p53 degradation by Mdm2 acetylation by Wang (2004)
  20. 10.1016/0378-1119(96)00151-5 / Gene / Genomic organization of the mouse double minute 2 gene by Jones (1996)
  21. 10.1006/geno.1996.0210 / Genomics / The organization and expression of the mdm2 gene by Montes de Oca Luna (1996)
  22. 10.1016/S0378-1119(01)00432-2 / Gene / Organization, expression, and localization of the murine mdmx gene and pseudogene by Parant (2001)
  23. 10.1101/gad.7.7a.1126 / Genes Dev. / The p53–mdm-2 autoregulatory feedback loop by Wu (1993)
  24. 10.1002/j.1460-2075.1993.tb05678.x / EMBO J. / mdm2 expression is induced by wild type p53 activity by Barak (1993)
  25. {'key': '10.1016/j.bbrc.2005.03.151_bib25', 'first-page': '993', 'article-title': 'MDM2, an introduction', 'volume': '1', 'author': 'Iwakuma', 'year': '2003', 'journal-title': 'Mol. Cancer Res.'} / Mol. Cancer Res. / MDM2, an introduction by Iwakuma (2003)
  26. {'key': '10.1016/j.bbrc.2005.03.151_bib26', 'first-page': '1839', 'article-title': 'Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53', 'volume': '61', 'author': 'Ramos', 'year': '2001', 'journal-title': 'Cancer Res.'} / Cancer Res. / Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53 by Ramos (2001)
  27. 10.1074/jbc.274.12.8299 / J. Biol. Chem. / A novel MDMX transcript expressed in a variety of transformed cell lines encodes a truncated protein with potent p53 repressive activity by Rallapalli (1999)
  28. 10.1038/ng714 / Nat. Genet. / Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53 by Parant (2001)
  29. 10.1128/MCB.22.15.5527-5538.2002 / Mol. Cell. Biol. / Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development by Migliorini (2002)
  30. {'key': '10.1016/j.bbrc.2005.03.151_bib30', 'first-page': '3221', 'article-title': 'Mdmx is a negative regulator of p53 activity in vivo', 'volume': '62', 'author': 'Finch', 'year': '2002', 'journal-title': 'Cancer Res.'} / Cancer Res. / Mdmx is a negative regulator of p53 activity in vivo by Finch (2002)
  31. 10.4161/cc.3.7.998 / Cell Cycle / Mdmx and Mdm2: brothers in arms? by Marine (2004)
  32. 10.1038/sj.onc.1208256 / Oncogene / Dapk1, encoding an activator of a p19ARF-p53 mediated apoptotic checkpoint, is a transcription target of p53 by Martoriati (2005)
  33. 10.1038/sj.onc.1202281 / Oncogene / Comparative study of the p53–mdm2 and p53–DMX interfaces by Bottger (1999)
  34. 10.1089/104454902320219077 / DNA Cell Biol. / MDMX inhibits the p300/CBP-mediated acetylation of p53 by Sabbatini (2002)
  35. 10.1128/MCB.24.13.5835-5843.2004 / Mol. Cell. Biol. / Amplification of Mdmx (or Mdm4) directly contributes to tumour formation by inhibiting p53-tumour suppressor activity by Danovi (2004)
  36. 10.1016/S0092-8674(01)00619-5 / Cell / Why is p53 acetylated? by Prives (2001)
  37. 10.1128/MCB.20.3.1001-1007.2000 / Mol. Cell. Biol. / MdmX protects p53 from Mdm2-mediated degradation by Jackson (2000)
  38. 10.1074/jbc.M003496200 / J. Biol. Chem. / Hdmx stabilizes Mdm2 and p53 by Stad (2000)
  39. 10.1093/embo-reports/kve227 / EMBO Rep. / Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms by Stad (2001)
  40. 10.1074/jbc.M108795200 / J. Biol. Chem. / Hdmx recruitment into the nucleus by Hdm2 is essential for its ability to regulate p53 stability and transactivation by Migliorini (2002)
  41. 10.1128/MCB.23.14.4929-4938.2003 / Mol. Cell. Biol. / Critical role for a central part of Mdm2 in the ubiquitylation of p53 by Meulmeester (2003)
  42. 10.1128/MCB.23.14.4939-4947.2003 / Mol. Cell. Biol. / Critical contribution of the MDM2 acidic domain to p53 ubiquitination by Kawai (2003)
  43. 10.1038/35023500 / Nat. Cell Biol. / An intact HDM2 RING-finger domain is required for nuclear exclusion of p53 by Boyd (2000)
  44. 10.1038/35023507 / Nat. Cell Biol. / The MDM2 RING-finger domain is required to promote p53 nuclear export by Geyer (2000)
  45. 10.1074/jbc.C200150200 / J. Biol. Chem. / Mutual dependence of MDM2 and MDMX in their functional inactivation of p53 by Gu (2002)
  46. 10.1073/pnas.2030930100 / Proc. Natl. Acad. Sci. USA / HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53 by Linares (2003)
  47. 10.1093/emboj/17.2.554 / EMBO J. / Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein by Roth (1998)
  48. 10.1128/MCB.22.21.7562-7571.2002 / Mol. Cell. Biol. / DNA damage induces MDMX nuclear translocation by p53-dependent and -independent mechanisms by Li (2002)
  49. 10.1074/jbc.M213034200 / J. Biol. Chem. / Hdmx protein stability is regulated by the ubiquitin ligase activity of Mdm2 by de Graaf (2003)
  50. 10.1128/MCB.23.15.5113-5121.2003 / Mol. Cell. Biol. / MDM2 promotes ubiquitination and degradation of MDMX by Pan (2003)
  51. 10.1074/jbc.M308295200 / J. Biol. Chem. / DNA damage-induced MDMX degradation is mediated by MDM2 by Kawai (2003)
  52. 10.1073/pnas.0408595102 / Proc. Natl. Acad. Sci. USA / Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage by Pereg (2005)
  53. 10.1074/jbc.274.12.8161 / J. Biol. Chem. / Multiple murine double minute gene 2 (MDM2) proteins are induced by ultraviolet light by Saucedo (1999)
  54. 10.1074/jbc.275.8.5733 / J. Biol. Chem. / p76(MDM2) inhibits the ability of p90(MDM2) to destabilize p53 by Perry (2000)
  55. 10.1038/sj.onc.1205137 / Oncogene / MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts by Gentiletti (2002)
  56. 10.1074/jbc.M311793200 / J. Biol. Chem. / MDM4 (MDMX) overexpression enhances stabilization of stress-induced p53 and promotes apoptosis by Mancini (2004)
  57. {'key': '10.1016/j.bbrc.2005.03.151_bib56', 'first-page': '6091', 'article-title': 'Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification', 'volume': '59', 'author': 'Riemenschneider', 'year': '1999', 'journal-title': 'Cancer Res.'} / Cancer Res. / Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification by Riemenschneider (1999)
  58. 10.1002/ijc.11023 / Int. J. Cancer / Refined mapping of 1q32 amplicons in malignant gliomas confirms MDM4 as the main amplification target by Riemenschneider (2003)
  59. 10.1126/science.1092472 / Science / In vivo activation of the p53 pathway by small-molecule antagonists of MDM2 by Vassilev (2004)
  60. 10.1158/1541-7786.29.2.1 / Mol. Cancer Res. / MDM2 and its splice variant messenger RNAs: expression in tumors and down-regulation using antisense oligonucleotides by Bartel (2004)
  61. 10.1002/jcb.10535 / J. Cell. Biochem. / Identification of a domain within MDMX-S that is responsible for its high affinity interaction with p53 and high-level expression in mammalian cells by Rallapalli (2003)
  62. 10.1038/nature737 / Nature / Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization by Li (2002)
  63. 10.1016/S1097-2765(04)00157-1 / Mol. Cell / A dynamic role of HAUSP in the p53–Mdm2 pathway by Li (2004)
  64. 10.1038/nature02501 / Nature / Tumour suppression: disruption of HAUSP gene stabilizes p53 by Cummins (2004)
  65. {'key': '10.1016/j.bbrc.2005.03.151_bib64', 'first-page': '1027', 'article-title': 'p53-independent functions of MDM2', 'volume': '1', 'author': 'Ganguli', 'year': '2003', 'journal-title': 'Mol. Cancer Res.'} / Mol. Cancer Res. / p53-independent functions of MDM2 by Ganguli (2003)
  66. 10.1016/S0960-9822(99)80367-4 / Curr. Biol. / MDM2 and MDMX bind and stabilize the p53-related protein p73 by Ongkeko (1999)
  67. 10.1016/S0014-5793(01)02124-X / FEBS Lett. / MDM2 and MDMX can interact differently with ARF and members of the p53 family by Wang (2001)
  68. 10.1038/416560a / Nature / p63 and p73 are required for p53-dependent apoptosis in response to DNA damage by Flores (2002)
  69. 10.1016/j.ccr.2004.06.005 / Cancer Cell / p63 and p73 are not required for the development and p53-dependent apoptosis of T cells by Senoo (2004)
  70. 10.1038/sj.onc.1204615 / Oncogene / Hdmx and Mdm2 can repress transcription activation by p53 but not by p63 by Little (2001)
  71. 10.1089/10445490152122433 / DNA Cell Biol. / Regulation of p63 function by Mdm2 and MdmX by Kadakia (2001)
  72. 10.1074/jbc.M010685200 / J. Biol. Chem. / MdmX binding to ARF affects Mdm2 protein stability and p53 transactivation by Jackson (2001)
  73. 10.1101/gad.11.6.714 / Genes Dev. / Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53 by Lundgren (1997)
  74. 10.1038/sj.onc.1202448 / Oncogene / MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice by Alkhalaf (1999)
  75. 10.1126/science.288.5471.1635 / Science / The genetic program of hematopoietic stem cells by Phillips (2000)
  76. 10.1073/pnas.95.26.15608 / Proc. Natl. Acad. Sci. USA / Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis by Jones (1998)
Dates
Type When
Created 20 years, 4 months ago (April 8, 2005, 7:44 a.m.)
Deposited 1 year, 6 months ago (Jan. 24, 2024, 12:04 p.m.)
Indexed 1 month ago (July 22, 2025, 6:33 a.m.)
Issued 20 years, 2 months ago (June 1, 2005)
Published 20 years, 2 months ago (June 1, 2005)
Published Print 20 years, 2 months ago (June 1, 2005)
Funders 0

None

@article{Marine_2005, title={Mdmx as an essential regulator of p53 activity}, volume={331}, ISSN={0006-291X}, url={http://dx.doi.org/10.1016/j.bbrc.2005.03.151}, DOI={10.1016/j.bbrc.2005.03.151}, number={3}, journal={Biochemical and Biophysical Research Communications}, publisher={Elsevier BV}, author={Marine, Jean-Christophe and Jochemsen, Aart G.}, year={2005}, month=jun, pages={750–760} }