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journal-article
Elsevier BV
Advanced Drug Delivery Reviews (78)
References
88
Referenced
236
10.1208/aapsj070110
/ The AAPS J. / Aqueous and cosolvent solubility data for drug-like organic compounds by Rytting (2005){'key': '10.1016/j.addr.2007.05.008_bib2', 'series-title': 'AQUASOL DATAbASE of Aqueous Solubility', 'author': 'Yalkowsky', 'year': '1998'}
/ AQUASOL DATAbASE of Aqueous Solubility by Yalkowsky (1998)10.1021/js9901007
/ J. Pharm. Sci. / The correlation and prediction of the solubility of compounds in water using an amended solvation energy relationship by Abraham (1999){'key': '10.1016/j.addr.2007.05.008_bib4', 'series-title': 'Solubility and Solubilization in Aqueous Media', 'author': 'Yalkowsky', 'year': '1999'}
/ Solubility and Solubilization in Aqueous Media by Yalkowsky (1999){'key': '10.1016/j.addr.2007.05.008_bib5', 'series-title': 'Absorption and Drug Development', 'author': 'Avdeef', 'year': '2003'}
/ Absorption and Drug Development by Avdeef (2003){'key': '10.1016/j.addr.2007.05.008_bib6', 'series-title': 'Solutility behavior of organic compounds', 'author': 'Grant', 'year': '1990'}
/ Solutility behavior of organic compounds by Grant (1990){'key': '10.1016/j.addr.2007.05.008_bib7', 'series-title': 'Aqueous Solubility: Methods of Estimation for Organic Compounds', 'author': 'Yalkowsky', 'year': '1992'}
/ Aqueous Solubility: Methods of Estimation for Organic Compounds by Yalkowsky (1992){'key': '10.1016/j.addr.2007.05.008_bib8', 'series-title': 'Handbook of Pharmaceutical Salts: Properties, Selection, and Use', 'first-page': '19–39', 'article-title': 'Solubility and dissolution of weak acids, bases, and salts', 'author': 'Pudipeddi', 'year': '2002'}
/ Handbook of Pharmaceutical Salts: Properties, Selection, and Use / Solubility and dissolution of weak acids, bases, and salts by Pudipeddi (2002){'key': '10.1016/j.addr.2007.05.008_bib9', 'first-page': '117', 'article-title': 'Phase-solubility techniques', 'volume': '4', 'author': 'Higuchi', 'year': '1965', 'journal-title': 'Adv. Anal. Chem. Instrum.'}
/ Adv. Anal. Chem. Instrum. / Phase-solubility techniques by Higuchi (1965){'key': '10.1016/j.addr.2007.05.008_bib10', 'series-title': 'The Practice of Medicinal Chemistry', 'first-page': '739', 'article-title': 'Preparation of water-soluble compounds through salt formation', 'author': 'Anderson', 'year': '1996'}
/ The Practice of Medicinal Chemistry / Preparation of water-soluble compounds through salt formation by Anderson (1996){'key': '10.1016/j.addr.2007.05.008_bib11', 'series-title': 'Handbook of Pharmaceutical Salts: Properties, Selection, and Use', 'first-page': '135', 'article-title': 'Salt selection strategies', 'author': 'Serajuddin', 'year': '2002'}
/ Handbook of Pharmaceutical Salts: Properties, Selection, and Use / Salt selection strategies by Serajuddin (2002){'key': '10.1016/j.addr.2007.05.008_bib12', 'series-title': 'Polymorphism in pharmaceutical industry', 'first-page': '309', 'article-title': 'Salt selection', 'author': 'Stahl', 'year': '2006'}
/ Polymorphism in pharmaceutical industry / Salt selection by Stahl (2006)10.1021/js960238e
/ J. Pharm. Sci. / Spectral methods for the characterization of polymorphs and solvates by Brittain (1997)10.1002/jps.20302
/ J. Pharm. Sci. / Trends in solubility of polymorphs by Pudipeddi (2005)10.1021/js9601896
/ J. Pharm. Sci. / Characterization and significance of the amorphous state in pharmaceutical systems by Hancock (1997)10.1023/B:PHAM.0000016235.32639.23
/ Pharm. Res. / Solubilizing excipients in oral and injectable formulations by Strickley (2004){'key': '10.1016/j.addr.2007.05.008_bib17', 'series-title': 'Characterization of Compounds in Solution — Theory and Practice', 'author': 'Streng', 'year': '2001'}
/ Characterization of Compounds in Solution — Theory and Practice by Streng (2001)10.2174/1568026013395100
/ Curr. Top. Med. Chem. / Physicochemical profiling (solubility, permeability, and charge state) by Avdeef (2001){'key': '10.1016/j.addr.2007.05.008_bib19', 'first-page': '399', 'article-title': 'Dissolution–solubility: pH, buffer, salt, dual-solid, and aggregation effects', 'volume': 'Vol. 5', 'author': 'Avdeef', 'year': '2007'}
/ Dissolution–solubility: pH, buffer, salt, dual-solid, and aggregation effects by Avdeef (2007)10.1002/jps.2600681019
/ J. Pharm. Sci. / Solubility determination of barely aqueous-soluble organic solids by Higuchi (1979)10.1023/A:1016059008464
/ Pharm. Res. / Intrinsic solubility estimation and pH-solubility behavior of cosalane (NSC658586), an extremely hydrphobic diprotic acid by Venkatesh (1996)10.1016/0378-5173(93)90003-X
/ Int. J. Pharm. / Solubility of ionization behavior of the antifungal α-(2,4-difluorophenyl)-α -[(1-(2-(2-pyridyl)phenylethenyl)]-1H-1,2,4-triazole-1-ethanol bismesylate (XD405) by Maurin (1993)10.1111/j.2042-7158.1978.tb13192.x
/ J.Pharm. Pharmacol. / Aggregation of antidepressant drugs in aqueous solution by Attwood (1978)10.1002/jps.2600680218
/ J.Pharm. Sci. / Solubility of doxycycline in aqueous solution by Bogardus (1979)10.1016/0378-5173(95)04317-9
/ Int. J. Pharm. / Determination of solution aggregation using solubility, conductivity, calorimetry, and pH measurement by Streng (1996)10.1016/0378-5173(95)04220-2
/ Int. J. Pharm. / Investigation of drug self-association in aqueous solution using calorimetry, conductivity, and osmometry by Zhu (1996)10.1023/A:1018948030811
/ Pharm. Res. / Salt and mesophase formation in aqueous suspensions of lauric acid by Smith (1993)10.1016/0378-5173(95)04102-8
/ Int. J. Pharm. / Solubility and solubilization properties of non-steroidal antiinflammatory drugs by Fini (1995)10.1007/s11095-006-9169-0
/ Pharm. Res. / Solubility-excipient classification gradient maps by Avdeef (2007)10.1002/jps.2600621021
/ J. Pharm. Sci. / Physicochemical properties of prostaglandin F2∝ (tromethamine salt): solubility behaviour, surface properties, and ionization constants by Roseman (1973)10.1002/(SICI)1520-6017(200002)89:2<268::AID-JPS14>3.0.CO;2-F
/ J. Pharm. Sci. / Dissolution of ionizable water-insoluble drugs: the combined effect of pH and surfactant by Jinno (2000)-
A. Avdeef, High-throughput measurements of solubility profiles, in: B. Testa, H. van de Waterbeemd, G. Folkers, R. Guy (Eds.), Pharmacokinetic Optimization in Drug Research, Verlag Helvetica Chimica Acta, Zürich and Wiley — VCH, Weinheim, 2001, pp. 305–326.
(
10.1002/9783906390437.ch18
) 10.1007/PL00012496
/ Cell. Mol. Life Sci. / Physicochemical profiling in drug research: a brief state-of-the-art of experimental techniques by Avdeef (2003)10.1021/la962060h
/ Langmuir / Ligand crystals and colloids in water-amiodarone systems by Bouligand (1998)10.1002/jps.2600641117
/ J. Pharm. Sci. / Micelle formation and its relationship to solubility behavior of 2-butyl-3-benzofuranyl-4-(2-(diethylamino) ethoxy)-3,5-diiodophenylketone hydrochloride by Ravin (1975){'key': '10.1016/j.addr.2007.05.008_bib36', 'first-page': '165', 'article-title': 'pH-metric solubility 1. Solubility–pH profiles from Bjerrum plots. Gibbs buffer and pKa in the solid state', 'volume': '4', 'author': 'Avdeef', 'year': '1998', 'journal-title': 'Pharm. Pharmacol. Commun.'}
/ Pharm. Pharmacol. Commun. / pH-metric solubility 1. Solubility–pH profiles from Bjerrum plots. Gibbs buffer and pKa in the solid state by Avdeef (1998)10.1023/A:1018908032686
/ Pharm. Res. / Solubilization of thiazolobenzimidazole using a combination of pH adjustment and complexation with 2-hydroxy-β-cyclodextrin by Tinwalla (1993)10.1002/jps.2600830814
/ J. Pharm. Sci. / Solubilization of a tripeptide HIV protease inhibitor using a combination of ionization and complexation with chemically modified cyclodextrins by Johnson (1994)10.1023/A:1016047215907
/ Pharm. Res. / The interaction of charged and uncharged drugs with neutral (HP-β-CD) and anionically charged (SBE7-β-CD) β-cyclodextrins by Okimoto (1996)10.1021/js980041h
/ J. Pharm. Sci. / Increased shelf-life of fosphenytoin: solubilization of a degradant, phenytoin, through complexation with (SBE)7m-β-CD by Narisawa (1998)10.1016/j.ejps.2006.06.006
/ Eur. J. Pharm. Sci. / Solubilization and dissolution of insoluble weak acid, ketoprofen: effect of pH combined with surfactant by Sheng (2006)10.1248/cpb.27.2468
/ Chem. Pharm. Bull. / Interaction of drugs with bile components. I. Effects of bile salts on the dissolution of indomethacin and phenylbutazone by Miyazaki (1979)10.1023/A:1015877929381
/ Pharm. Res. / Solubilization and wetting effects of bile salts in the dissolution of steroids by Bakatselou (1991)10.1023/A:1016062224568
/ Pharm. Res. / Estimation of the increase in solubility of drugs as a function of bile salt concentration by Mithani (1996)10.1023/A:1018967401000
/ Pharm. Res. / The effects of bile salts and lipids on the physicochemical behavior of gemfibrozil by Luner (1994)10.1016/j.ejps.2006.05.004
/ Eur. J. Pharm. Sci. / Biorelevant dissolution media as a predictive tool for glyburide a class II drug by Wei (2006)10.1023/A:1007526826979
/ Pharm. Res. / pH-metric solubility. 2. Correlation between the acid-base titration and the saturation shake-flask solubility–pH methods by Avdeef (2000)10.1016/S0928-0987(01)00190-7
/ Eur. J. Pharm. Sci. / pH-metric solubility. 3. Dissolution titration template method for solubility determination by Avdeef (2001)10.1002/jps.20212
/ J. Pharm. Sci. / Comparison of a miniaturized shake-flask solubility method with automated potentiometric acid/base titrations and calculated solubilities by Glomme (2005){'key': '10.1016/j.addr.2007.05.008_bib50', 'series-title': 'Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies', 'first-page': '259', 'article-title': 'Predicting the intestinal solubility of poorly soluble molecules', 'author': 'Glomme', 'year': '2006'}
/ Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies / Predicting the intestinal solubility of poorly soluble molecules by Glomme (2006)10.1016/j.ejps.2004.04.006
/ Eur. J. Pharm. Sci. / Accuracy of calculated pH-dependent aqueous drug solubility by Bergström (2004)10.1002/jps.20814
/ J. Pharm. Sci. / Development of a partially automated solubility screening (PASS) assay for early drug development by Alsenz (2007)10.1002/jps.20628
/ J. Pharm. Sci. / High throughput solubility measurement with automated polarized light microscopy analysis by Sugano (2006)10.2174/1386207023330075
/ Comb. Chem. High Throughput Screen. / Evaluation of a method for high throughput solubility determination using a multi-wavelength UV plate reader by Chen (2002)10.1023/A:1025021603288
/ Pharm. Res. / A high-throughput combinatorial approach for the discovery of a Cremophor EL-free paclitaxel formulation by Chen (2003)10.1002/1520-6017(200104)90:4<521::AID-JPS1009>3.0.CO;2-B
/ J. Pharm. Sci. / Comparison of chromatographic and spectroscopic methods used to rank compounds for aqueous solubility by Pan (2001){'key': '10.1016/j.addr.2007.05.008_bib57', 'series-title': 'Validation of Solubility Measurements Using Ultra-Filtration Liquid Chromatography Mass Spectrometry (UF-LC/MS), Amer. Soc. Mass Spec. 48th Annual Conference', 'author': 'Hayward', 'year': '2000'}
/ Validation of Solubility Measurements Using Ultra-Filtration Liquid Chromatography Mass Spectrometry (UF-LC/MS), Amer. Soc. Mass Spec. 48th Annual Conference by Hayward (2000)10.1002/jps.1134
/ J. Pharm. Sci. / High throughput physicochemical profiling for drug discovery by Kerns (2001)10.1002/jps.2600731203
/ J. Pharm. Sci. / General treatment of pH-solubility profiles of weak acids and bases and the effect of different acids on the solubility of a weak base by Streng (1984){'key': '10.1016/j.addr.2007.05.008_bib60', 'series-title': 'Waiver of in vivo bioavailability and bioequivalence studies for immediate release solid oral dosage forms based on a biopharmaceutics classification system', 'author': 'Guidance for Industry', 'year': '2000'}
/ Waiver of in vivo bioavailability and bioequivalence studies for immediate release solid oral dosage forms based on a biopharmaceutics classification system by Guidance for Industry (2000)10.1002/jps.10107
/ J. Pharm. Sci. / Solubility of E2050 at various pH: a case in which the apparent solubility is affected by the amount of excess solid by Wang (2002)10.1007/s11095-005-6247-7
/ Pharm. Res. / Impact of the amount of excess solids on apparent solubility by Kawakami (2005){'key': '10.1016/j.addr.2007.05.008_bib63', 'series-title': 'The Determination of Ionization Constants', 'author': 'Albert', 'year': '1984'}
/ The Determination of Ionization Constants by Albert (1984)10.1021/ac50036a045
/ Anal. Chem. / Accurate measurements of the concentration of hydrogen ions with a glass electrode: calibrations using the prideaux and other universal buffer solutions and a computer-controlled automatic titrator by Avdeef (1978)10.1002/jps.2600820214
/ J. Pharm. Sci. / pH-metric logP. 2. Refinement of partition coefficients and ionization constants of multiprotic substances by Avdeef (1993)10.1007/s11095-006-9137-8
/ Pharm. Res. / PAMPA-excipient classification gradient maps by Bendels (2006)10.3109/03639048309039887
/ Drug Dev. Ind. Pharm. / Dissociation constants, solubilities and dissociation rates of some selected nonsteroidal antiinflammatories by Herzfeldt (1983)10.1002/ardp.19843170314
/ Arch. Pharm. / pH-solubility relationship and partition coefficients for some anti-inflammatory arylaliphatic acids by Chiarini (1984)10.1002/jps.2600670918
/ J. Pharm. Sci. / pH-solubility profiles of organic carboxylic acids and their salts by Chowhan (1978)10.1016/S0378-5173(98)00257-9
/ Int. J. Pharm. / Effects of surface active characteristics and solid state forms on the pH solubility profiles of drug-salt systems by Ledwidge (1998)10.1002/jps.2600660724
/ J. Pharm. Sci. / Solubility and ionization characteristics of phenytoin by Schwartz (1977)10.1016/0378-5173(80)90051-4
/ Int. J. Pharm. / Pro-drugs as drug delivery systems, VIII Bioreversible derivatization of hydantoin by N-hydroxymethylation by Bundgaard (1980)10.1002/jps.2600730905
/ J. Pharm. Sci. / pH-solubility profile of papaverine hydrochloride and its relationship to the dissolution rate of sustained-release pellets by Serajuddin (1984)10.1248/cpb.27.1441
/ Chem. Pharm. Bull. / Solubility characteristics of weak bases and their hydrochloride salts in hydrochloric acid solutions by Miyazaki (1979)10.1023/A:1011900527021
/ Pharm. Res. / Co-administration of a water-soluble polymer increases the usefulness of cyclodextrins in solid oral dosage forms by Savolainen (1998)10.1021/js9801889
/ J. Pharm. Sci. / Combined effect of complexation and pH on solubilization by Li (1998)10.1021/jf030332y
/ J. Agric. Food Chem. / Formation of natamycin-cyclodextrin inclusion complexes and their characterization by Koontz (2003)10.1016/j.ijpharm.2004.11.013
/ Int. J. Pharm. / Preformulation study of the inclusion complex warfarin-β-cyclodextrin by Zingone (2005)10.1016/j.bioorg.2004.04.004
/ Bioorg. Chem. / Evidence for the 2:1 molecular recognition and inclusion behavior between β- and γ-cyclodextrins and cinchonine by Wen (2004)10.1016/j.ejps.2005.04.020
/ Eur. J. Pharm. Sci. / Effect of RM-β-CD on sublingual bioavailability of Δ9-tetrahydrocannabinol in rabbits by Mannila (2005){'key': '10.1016/j.addr.2007.05.008_bib81', 'first-page': '377', 'article-title': 'Interaction of omeprazole with a methylated derivative of β-cyclodextrin: phase solubility, NMR spectroscopy and molecular simulation', 'volume': '24', 'author': 'Figueiras', 'year': '2006', 'journal-title': 'Pharm. Sci.'}
/ Pharm. Sci. / Interaction of omeprazole with a methylated derivative of β-cyclodextrin: phase solubility, NMR spectroscopy and molecular simulation by Figueiras (2006)10.1016/j.ejps.2006.10.008
/ Eur. J. Pharm. Sci. / Cyclodextrin/imatinib complexation: binding mode and charge dependent stabilities by Béni (2007)10.1002/jps.2600700604
/ J. Pharm. Sci. / Precaution on use of hydrochloride salts in pharmaceutical formulation by Miyazaki (1981)10.1002/jps.2600740803
/ J. Pharm. Sci. / Predictive relationships in the water solubility of salts of a nonsteroidal anti-inflammatory drug by Anderson (1985)10.1016/0378-5173(90)90167-3
/ Int. J. Pharm. / Aqueous solubility properties of a dibasic peptide-like compound by Garren (1990)10.1016/S0378-5173(00)00350-1
/ Int. J. Pharm. / Salt selection and characterization of LY333531 mesylate monohydrate by Engel (2000)10.1016/S0099-5428(08)60380-9
/ Anal. Profiles Drug Subst. / Terfenadine by Badwan (1990){'key': '10.1016/j.addr.2007.05.008_bib88', 'first-page': '32', 'article-title': 'Pharmaceutical preformulation: the physicochemical properties of drug substances', 'author': 'Wells', 'year': '1988'}
/ Pharmaceutical preformulation: the physicochemical properties of drug substances by Wells (1988)
Dates
Type | When |
---|---|
Created | 18 years, 3 months ago (May 30, 2007, 7:58 a.m.) |
Deposited | 6 years, 8 months ago (Jan. 6, 2019, 9:22 p.m.) |
Indexed | 31 minutes ago (Sept. 7, 2025, 8:12 p.m.) |
Issued | 18 years, 2 months ago (July 1, 2007) |
Published | 18 years, 2 months ago (July 1, 2007) |
Published Print | 18 years, 2 months ago (July 1, 2007) |
@article{Avdeef_2007, title={Solubility of sparingly-soluble ionizable drugs}, volume={59}, ISSN={0169-409X}, url={http://dx.doi.org/10.1016/j.addr.2007.05.008}, DOI={10.1016/j.addr.2007.05.008}, number={7}, journal={Advanced Drug Delivery Reviews}, publisher={Elsevier BV}, author={Avdeef, Alex}, year={2007}, month=jul, pages={568–590} }