Crossref
journal-article
Elsevier BV
Cancer Cell (78)
References
50
Referenced
927
{'key': '10.1016/S1535-6108(04)00083-2_BIB1', 'first-page': '76', 'article-title': 'A potential role for activated HER-2 in prostate cancer', 'volume': '27', 'author': 'Agus', 'year': '2000', 'journal-title': 'Semin. Oncol.'}
/ Semin. Oncol. / A potential role for activated HER-2 in prostate cancer by Agus (2000)10.1016/S1535-6108(02)00097-1
/ Cancer Cell / Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth by Agus (2002)10.1038/348693a0
/ Nature / The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily by Aroian (1990)10.1016/S0014-4827(02)00104-0
/ Exp. Cell Res. / ErbB-targeted therapeutic approaches in human cancer by Arteaga (2003)10.1016/S1097-2765(03)00350-2
/ Mol. Cell / An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors by Burgess (2003)10.1073/pnas.89.10.4285
/ Proc. Natl. Acad. Sci. USA / Humanization of an anti-p185HER2 antibody for human cancer therapy by Carter (1992)10.3233/BD-1999-11109
/ Breast Disease / Development of Herceptin by Carter (2000)10.1126/science.1074611
/ Science / Structure of the extracellular region of HER3 reveals an interdomain tether by Cho (2002)10.1038/nature01392
/ Nature / Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab by Cho (2003)10.1038/74704
/ Nat. Med. / Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets by Clynes (2000)10.1200/JCO.1999.17.9.2639
/ J. Clin. Oncol. / Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease by Cobleigh (1999)10.1006/jmbi.1993.1099
/ J. Mol. Biol. / X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling by Eigenbrot (1993)10.1016/S0014-4827(02)00102-7
/ Exp. Cell Res. / Neuregulins by Falls (2003){'key': '10.1016/S1535-6108(04)00083-2_BIB14', 'first-page': '1550', 'article-title': 'Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product', 'volume': '50', 'author': 'Fendly', 'year': '1990', 'journal-title': 'Cancer Res.'}
/ Cancer Res. / Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product by Fendly (1990)10.1093/emboj/19.17.4632
/ EMBO J. / Extracellular domains drive homo- but not hetero-dimerization of erbB receptors by Ferguson (2000)10.1016/S1097-2765(03)00047-9
/ Mol. Cell / EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization by Ferguson (2003)10.1016/S0014-4827(02)00095-2
/ Exp. Cell Res. / Mechanism of action of erbB tyrosine kinase inhibitors by Fry (2003)10.1016/S0092-8674(02)00940-6
/ Cell / Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha by Garrett (2002)10.1016/S1097-2765(03)00048-0
/ Mol. Cell / The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors by Garrett (2003)10.1093/emboj/16.7.1647
/ EMBO J. / ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling by Graus-Porta (1997)10.1021/bi9614141
/ Biochemistry / A model for the activation of the epidermal growth factor receptor kinase involvement of an asymmetric dimer? by Groenen (1997)10.1096/fasebj.9.8.7768349
/ FASEB J. / Protein kinases 6. The eukaryotic protein kinase superfamily by Hanks (1995)10.1016/S0014-4827(02)00099-X
/ Exp. Cell Res. / The ErbB receptors and their role in cancer progression by Holbro (2003)10.1016/S0021-9258(18)54400-8
/ J. Biol. Chem. / Cell transformation potential of a HER2 transmembrane domain deletion mutant retained in the endoplasmic reticulum by Hudziak (1991)10.1016/S0014-4827(02)00098-8
/ Exp. Cell Res. / Epidermal growth factor receptor by Jorissen (2003)10.1021/bi00139a003
/ Biochemistry / Antigen binding thermodynamics and antiproliferative effects of chimeric and humanized anti-p185HER2 antibody Fab fragments by Kelley (1992)10.1016/0092-8674(85)90208-9
/ Cell / The Drosophila EGF receptor gene homolog by Livneh (1985)10.1053/gast.2001.24844
/ Gastroenterology / Targeting cyclooxygenase 2 and HER-2/neu pathways inhibits colorectal carcinoma growth by Mann (2001){'key': '10.1016/S1535-6108(04)00083-2_BIB29', 'first-page': '5485', 'article-title': 'Inhibition of ligand-mediated HER2 activation in androgen-independent prostate cancer', 'volume': '62', 'author': 'Mendoza', 'year': '2002', 'journal-title': 'Cancer Res.'}
/ Cancer Res. / Inhibition of ligand-mediated HER2 activation in androgen-independent prostate cancer by Mendoza (2002){'key': '10.1016/S1535-6108(04)00083-2_BIB30', 'first-page': '4744', 'article-title': 'Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells', 'volume': '61', 'author': 'Molina', 'year': '2001', 'journal-title': 'Cancer Res.'}
/ Cancer Res. / Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells by Molina (2001)10.1073/pnas.93.13.6252
/ Proc. Natl. Acad. Sci. USA / Structural analysis of p185c-neu and epidermal growth factor receptor tyrosine kinases by Murali (1996)10.1107/S0907444996012255
/ Acta Crystallogr. D / Refinement of Macromolecular Structures by the Maximum-Likelihood Method by Murshudov (1997)10.1107/S0108767393007597
/ Acta Crystallogr. A / AMoRe by Navaza (1994)10.1016/S0092-8674(02)00963-7
/ Cell / Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains by Ogiso (2002)10.1093/emboj/19.13.3159
/ EMBO J. / The ErbB signaling network by Olayioye (2000)10.1093/protein/3.6.547
/ Protein Eng. / Mammalian cell transient expression of tissue factor for the production of antigen by Paborsky (1990)10.3233/BD-1999-11108
/ Breast Disease / HER2 as a predictor of therapeutic response in breast cancer by Paik (2000)10.1002/stem.160413
/ Stem Cells / The HER-2/neu oncogene in breast cancer by Ross (1998)10.1074/jbc.274.2.859
/ J. Biol. Chem. / A discrete three-amino acid segment (LVI) at the C-terminal end of kinase-impaired ErbB3 is required for transactivation of ErbB2 by Schaefer (1999)10.1016/S0092-8674(00)00114-8
/ Cell / Cell signaling by receptor tyrosine kinases by Schlessinger (2000)10.1126/science.3798106
/ Science / Human breast cancer by Slamon (1987)10.1056/NEJM200103153441101
/ N. Engl. J. Med. / Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2 by Slamon (2001)10.1074/jbc.M207135200
/ J. Biol. Chem. / Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor by Stamos (2002)10.1007/s002390010043
/ J. Mol. Evol. / Evolutionary analysis of the ErbB receptor and ligand families by Stein (2000)10.1016/S0022-2836(02)00264-4
/ J. Mol. Biol. / Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis by Vajdos (2002)10.1200/JCO.20.3.719
/ J. Clin. Oncol. / Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer by Vogel (2002)10.1038/314178a0
/ Nature / A Drosophila genomic sequence with homology to human epidermal growth factor receptor by Wadsworth (1985)10.1186/1471-2105-2-4
/ BMC Bioinformatics / The relationship between the L1 and L2 domains of the insulin and epidermal growth factor receptors and leucine-rich repeat modules by Ward (2001)10.4049/jimmunol.157.11.4986
/ J. Immunol. / Humanization of an anti-lymphocyte function-associated antigen (LFA)-1 monoclonal antibody and reengineering of the humanized antibody for binding to rhesus LFA-1 by Werther (1996)10.1038/35052073
/ Nat. Rev. Mol. Cell Biol. / Untangling the ErbB signalling network by Yarden (2001)
Dates
Type | When |
---|---|
Created | 21 years, 4 months ago (April 21, 2004, 6:28 a.m.) |
Deposited | 2 years, 4 months ago (April 28, 2023, 8:01 a.m.) |
Indexed | 1 day, 18 hours ago (Sept. 4, 2025, 9:53 a.m.) |
Issued | 21 years, 5 months ago (April 1, 2004) |
Published | 21 years, 5 months ago (April 1, 2004) |
Published Print | 21 years, 5 months ago (April 1, 2004) |
@article{Franklin_2004, title={Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex}, volume={5}, ISSN={1535-6108}, url={http://dx.doi.org/10.1016/s1535-6108(04)00083-2}, DOI={10.1016/s1535-6108(04)00083-2}, number={4}, journal={Cancer Cell}, publisher={Elsevier BV}, author={Franklin, Matthew C and Carey, Kendall D and Vajdos, Felix F and Leahy, Daniel J and de Vos, Abraham M and Sliwkowski, Mark X}, year={2004}, month=apr, pages={317–328} }