Crossref
journal-article
Elsevier BV
Drug Discovery Today (78)
References
46
Referenced
121
10.1128/AAC.35.9.1697
/ Antimicrob. Agents Chemother. / More extended spectrum β-lactamases by Jacoby (1991){'key': '10.1016/S1359-6446(01)01774-3_BIB2', 'first-page': '1', 'article-title': "DOE's microbial genomics program focuses on high-throughput draft sequencing", 'volume': '14', 'author': 'Amber', 'year': '2000', 'journal-title': 'The Scientist'}
/ The Scientist / DOE's microbial genomics program focuses on high-throughput draft sequencing by Amber (2000)10.1016/S1359-6446(98)01273-2
/ Drug Discov. Today / Antibiotic discovery: is it all in the genes? by Brown (1998){'key': '10.1016/S1359-6446(01)01774-3_BIB4', 'first-page': '177', 'article-title': 'The impact of genomics on novel antibacterial targets', 'volume': '3', 'author': 'Payne', 'year': '2000', 'journal-title': 'Curr. Op. Drug Discov. Develop.'}
/ Curr. Op. Drug Discov. Develop. / The impact of genomics on novel antibacterial targets by Payne (2000)10.1128/JB.182.15.4319-4327.2000
/ J. Bacteriol. / Identification, evolution and essentiality of the mevalonate pathway for isopretentyl diphosphate biosynthesis in Gram-positive cocci by Wilding (2000)10.1073/pnas.94.11.5588
/ Proc. Natl. Acad. Sci. U. S. A. / Animal fatty acid synthase: functional mapping and cloning and expression of the domain I constituent activities by Chirala (1997)10.1016/S0021-9258(19)50498-7
/ J. Biol. Chem. / Isolation and characterization of the β-ketoacyl-acyl carrier protein synthase III gene (FabH) from Escherichia coli K-12 by Tsay (1992)10.1016/S0021-9258(19)36787-0
/ J. Biol. Chem. / Purification and characterization of 3-ketoacyl-acyl carrier protein synthase III from spinach. A condensing enzyme utilizing acetyl-coenzyme A to initiate fatty acid synthesis by Clough (1992)10.1073/pnas.95.21.12352
/ Proc. Natl. Acad. Sci. U. S. A / Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum by Waller (1998)10.1021/bi00437a001
/ Biochemistry / Fatty acid synthase, a proficient multifunctional enzyme by Wakil (1989)10.1126/science.8284673
/ Science / InhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis by Banerjee (1994)10.1126/science.279.5347.98
/ Science / Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis by Rozwarski (1998)10.1126/science.280.5369.1607
/ Science / Inhibition of a Mycobacterium tuberculosis β-ketoacyl ACP synthase by isoniazid by Mdluli (1998)10.1128/MR.57.3.522-542.1993
/ Microbiol. Rev. / Regulation of fatty acid biosynthesis in Escherichia coli by Magnuson (1993)10.1074/jbc.M005611200
/ J. Biol. Chem. / The enoyl-[acyl-carrier-protein] reductases FabI and FabL from Bacillus subtilis by Heath (2000)- Debouck, C. et al., (1999) Staphylococcus aureus FabH. EP916730A2
- Huang, J. and McDevitt, D., (1998) Staphylococcus aureus FabG. US6110704
10.1074/jbc.275.7.4654
/ J. Biol. Chem. / Inhibition of the Staphylococcus aureus NADPH-dependent enoyl-acyl carrier protein reductase by triclosan and hexachlorophene by Heath (2000)- Gentry, D.R. et al., (1998) Staphylococcus aureus malonyl-CoA:ACP transacylase (Fab D). EP843016-A2
- Gentry, D.R. et al. (1998) Streptococcus pneumoniae FabH. WO9817779-A1
- Gentry, D.R. (1998) Streptococcus pneumoniae FabD. WO9822133-A1
10.1128/JB.181.17.5498-5504.1999
/ J. Bacteriol. / Characterization of a Pseudomonas aeruginosa fatty acid biosynthetic gene cluster; purification of acyl carrier protein (ACP) and malonyl-coenzyme A: ACP transacylase (Fab D) by Kutchma (1999)10.1128/JB.181.17.5489-5497.1999
/ J. Bacteriol. / Characterization of Pseudomonas aeruginosa enoyl-acyl carrier protein reductase (FabI): a target for the antimicrobial triclosan and its role in acylated homoserine lactone synthesis by Hoang (1999)10.1038/35022656
/ Nature / A triclosan-resistant bacterial enzyme by Heath (2000)10.1046/j.1365-2958.2000.01725.x
/ Mol. Microbiol. / A genomic analysis of two-component signal transduction in Streptococcus pneumoniae by Throup (2000){'key': '10.1016/S1359-6446(01)01774-3_BIB26', 'first-page': '377', 'article-title': 'Antibacterial borzaro derivatives', 'volume': '8', 'author': 'Gronowitz', 'year': '1971', 'journal-title': 'Acta Pharm. Suecica'}
/ Acta Pharm. Suecica / Antibacterial borzaro derivatives by Gronowitz (1971)10.1093/jac/20.1.37
/ J. Antimicrob. Chemother. / Effect of diazaborine derivative (Sa 84.474) on the virulence of Escherichia coli by Lam (1987)10.1128/jb.171.12.6555-6565.1989
/ J. Bacteriol. / EnvM genes of Salmonella typhimurium and Escherichia coli. by Turnowsky (1989)10.1126/science.274.5295.2107
/ Science / A mechanism of drug action revealed by structural studies of enoyl reductase by Baldock (1996)10.1016/S0076-6879(81)72041-X
/ Methods Enzymol. / Cerulenin by Omura (1981)10.7164/antibiotics.35.411
/ J. Antibiot. / Thiolactomycin, a new antibiotic IV. Biological properties and chemotherapeutic activity in mice by Miyakawa (1982)10.1038/28970
/ Nature / Triclosan targets lipid synthesis [letter] by McMurry (1998)10.1074/jbc.273.46.30316
/ J. Biol. Chem. / Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis by Heath (1998)10.1021/bi9907779
/ Biochemistry / Kinetic and structural characteristics of the inhibition of enoyl(acyl carrier protein) reductase by triclosan by Ward (1999)10.1006/abio.2000.4594
/ Anal. Biochem. / Development of a scintillation proximity assay for β-ketoacyl carrier protein Synthase III by He (2000)10.1021/ja983468z
/ J. Am. Chem. Soc. / Engineering a cell-free murein biosynthetic pathway: Combinatorial enzymology in drug discovery by Wong (1998)- Bergsma, D.J. et al., (2000) Human FAS. WO051430A1
10.1074/jbc.274.51.36465
/ J. Biol. Chem. / Crystal structure of β-ketoacyl-acyl carrier protein synthase III. A key condensing enzyme in bacterial fatty acid biosynthesis by Qiu (1999)10.1006/jmbi.2000.4457
/ J. Mol. Biol. / Refined structures of β-ketoacyl-acyl carrier protein synthase III by Qiu (2001)10.1110/ps.8.11.2529
/ Protein Sci. / Molecular basis of triclosan activity involves a flipping loop in the active site by Qiu (1999)10.1074/jbc.274.16.11110
/ J. Biol. Chem. / Mechanism of triclosan inhibition of bacterial fatty acid synthesis by Heath (1999)-
Levy, C.W. et al., Molecular basis of triclosan activity [letter]. Nature 398, 383–384
(
10.1038/18803
) 10.1074/jbc.274.10.6031
/ J. Biol. Chem. / Structure of the complex between the antibiotic cerulenin and its target, β-ketoacyl-acyl carrier protein synthase by Moche (1999)10.1016/S0378-1119(00)00325-5
/ Gene / Regulated gene expression in Staphylococcus aureus for identifying conditional lethal phenotypes and antibiotic mode of action by Zhang (2000)- Heerding, D. and Newlander, K.A., (2000) Antibacterial compounds. WO00071120
- Miller, W.H. et al. (2000) FabI Inhibitors. WO00063187
Dates
Type | When |
---|---|
Created | 23 years, 1 month ago (July 25, 2002, 1:07 p.m.) |
Deposited | 4 years, 3 months ago (May 8, 2021, 7:58 p.m.) |
Indexed | 2 months, 2 weeks ago (June 11, 2025, 9:46 a.m.) |
Issued | 24 years, 3 months ago (May 1, 2001) |
Published | 24 years, 3 months ago (May 1, 2001) |
Published Print | 24 years, 3 months ago (May 1, 2001) |
@article{Payne_2001, title={Bacterial fatty-acid biosynthesis: a genomics-driven target for antibacterial drug discovery}, volume={6}, ISSN={1359-6446}, url={http://dx.doi.org/10.1016/s1359-6446(01)01774-3}, DOI={10.1016/s1359-6446(01)01774-3}, number={10}, journal={Drug Discovery Today}, publisher={Elsevier BV}, author={Payne, David J and Warren, Patrick V and Holmes, David J and Ji, Yinduo and Lonsdale, John T}, year={2001}, month=may, pages={537–544} }